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SpotCheck: A Skin Cancer Diagnostic Accuracy Study Comparing Teledermoscopy with and without Electrical Impedance Spectroscopy to In-Person Dermatologist Evaluation of Patient-Identified Lesions Concerning them for Skin Cancer

Ingrassia, Jenne P; Bajaj, Shirin; Kolla, Avani; Li, Vivienne; Shah, Payal; Gulati, Nicholas; Criscito, Maressa C; Xing, Yiping; Lopez, Adriana; Tran, Duy C; Ramachandran, Vignesh; Kakpovbia, Efe; Meehan, Shane; Shao, Yongzhao; Lo Sicco, Kristen; Milam, Emily C; Bieber, Amy K; Levine, Amanda; Liebman, Tracey N; Stein, Jennifer A; Polsky, David
PMID: 39528165
ISSN: 1097-6787
CID: 5752722

Top DEI Topics to Incorporate Into Dermatology Residency Training: An Electronic Delphi Consensus Study

Encarnación-Cortés, Valerie S; Rodriguez, Ivan; Rinderknecht, Fatuma-Ayaan; Admassu, Natnaelle; Phillips, Gregory; Castillo-Valladares, Herbert; Tarbox, Michelle; Peebles, Jon Klinton; Stratman, Erik J; Altman, Emily M; Pimentel, Matthew A; Elbuluk, Nada; Parekh, Palak; Daveluy, Steven; James, William; Kim, Soo Jung; Rosmarin, David; Kakpovbia, Efe; Silverberg, Jonathan I; Bowers, Sacharitha; Vasquez, Rebecca; Worswick, Scott D; Ahmed, Ammar M
Current dermatology residency education may be deficient in curricular topics and training related to diversity, equity, and inclusion (DEI). Integrating more DEI topics within residency curricula may improve clinical care delivered to diverse populations and improve cultural humility among trainees. The objective of this electronic Delphi (e-Delphi) study was to reach a consensus on the most important DEI topics for inclusion in dermatology residency program curricula nationwide. Sixty-one DEI-related topics were proposed by an expert panel consisting of dermatologists from the Association of Professors of Dermatology DEI subcommittee and the American Academy of Dermatology Diversity Task Force. Two rounds of anonymous electronic surveys based on a 5-point Likert scale were administered using a modified e-Delphi design. Voluntary participants including residents and academic dermatologists were self-selected after an email was sent to the Association of Professors of Dermatology listserve.
PMID: 39413328
ISSN: 2326-6929
CID: 5711662

Enhancing adherence for total body skin examination in post-surgical veterans: an interventional study at an urban Veterans Affairs center [Letter]

Ramachandran, Vignesh; Kakpovbia, Efe; Juarez, Michelle C; Jairath, Neil; Nemcevic, Andjela; Akoh, Christine C; Ahearn, Ian M; Tattersall, Ian W; Lee, Nayoung; Latkowski, Jo-Ann M; Zampella, John G
PMCID:11285472
PMID: 39075619
ISSN: 2054-9369
CID: 5684832

Efficacy of topical treatments for mild-to-moderate acne: A systematic review and meta-analysis of randomized control trials

Kakpovbia, Efe E; Young, Trevor; Milam, Emily C; Qian, Yingzhi; Yassin, Sallie; Nicholson, Joey; Hu, Jiyuan; Troxel, Andrea B; Nagler, Arielle R
Acne is a common skin condition, but little data exist on the comparative efficacy of topical acne therapies. We conducted a systematic review and network meta-analysis to evaluate the efficacy of topical therapies for mild-to-moderate acne. Searches in PubMed/MEDLINE, Cochrane CENTRAL via Ovid, Embase via Ovid and Web of Science were conducted on 29 November 2021. Randomized controlled trials examining ≥12 weeks of topical treatments for acne vulgaris in subjects aged 12 and older were included. Main outcomes were absolute or percent change in acne lesion count and treatment success on the Investigator's Global Assessment scale. Thirty-five randomized clinical trials with 33,472 participants comparing nine different topical agents were included. Adapalene-benzoyl peroxide (BPO), clindamycin-BPO and clindamycin-tretinoin demonstrated the greatest reduction in non-inflammatory (ratio of means [RoM] 1.76; 95% CI [1.46; 2.12], RoM 1.70; 95% CI [1.44; 2.02] and RoM 1.87; 95% CI [1.53; 2.30], respectively), inflammatory (RoM 1.56; 95% CI [1.44; 1.70], RoM 1.49; 95% CI [1.39; 1.60] and RoM 1.48; 95% CI [1.36; 1.61], respectively) and total lesion count (ROM 1.67; 95% CI [1.47; 1.90], RoM 1.59; 95% CI [1.42; 1.79] and RoM 1.64; 95% CI [1.42; 1.89], respectively) compared to placebo. All single agents outperformed placebo except tazarotene, which did not significantly outperform placebo for inflammatory and non-inflammatory lesion count reduction. Most combination agents significantly outperformed their individual components in lesion count reduction and global assessment scores, except for clindamycin-tretinoin and clindamycin-BPO, which did not significantly outperform tretinoin (RoM 1.13; 95% CI [0.94; 1.36]) and BPO (RoM = 1.15, 95% CI [0.98; 1.36]), respectively, for non-inflammatory lesion reduction. There was no significant difference amongst most single agents when evaluating lesion count reduction. Combination agents are generally most effective for mild-to-moderate acne; however for non-inflammatory acne, the addition of clindamycin in topical regimens is unnecessary and should be avoided.
PMID: 38943431
ISSN: 1468-3083
CID: 5686752

Disparities in Janus kinase inhibitor access for alopecia areata: a retrospective analysis

Klein, Elizabeth J; Taiwò, Dolly; Kakpovbia, Efe; Laughter, Melissa; Nohria, Ambika; Lo Sicco, Kristen I
PMCID:11164017
PMID: 38860233
ISSN: 2352-6475
CID: 5668912

Central centrifugal cicatricial alopecia in Black men: A case series highlighting key clinical features in this cohort [Case Report]

Lubov, Janet E; Okereke, Uchenna R; Clapp, Brittney; Toyohara, Jennifer; Taiwò, Dolly; Kakpovbia, Efe; Lo Sicco, Kristen; Adotama, Prince
PMID: 37600725
ISSN: 2352-5126
CID: 5598052

Impact of Laboratory Work Up and Supplementation on Alopecia Patients: A Single-Center Retrospective Chart Review

Kakpovbia, Efe; Ugonabo, Nkemjika; Chen, Alan; Adhikari, Samrachana; Ogbechie-Godec, Oluwatobi A; Sicco, Kristen Lo; Shapiro, Jerry
Evaluation of alopecia often includes laboratory testing for ferritin, thyroid stimulating hormone, vitamin D, and zinc as previous studies have found associations between non-scarring alopecia and vitamin deficiencies. These studies are limited by small sample sizes, and subsequent analyses showed conflicting results. This study aims to explore laboratory abnormalities in non-scarring alopecia and examine whether supplementation is associated with increased hair growth. A total of 131 patients completed at least two visits by a hair specialist at NYU’s Faculty Group Practice. They had quantitative hair measurements taken at each visit and laboratory tests performed at the first visit. There were 20 (15.3%) patients with abnormal lab results. The most common vitamin deficiency was ferritin (6.5%). Forty-two (32%) patients received supplementations that specifically addressed their vitamin or hormone deficiency. Multivariate regression analysis showed that supplementation did not significantly impact hair density or diameter (P=0.73; P=0.96, respectively). Baseline hair density and diameter were positively associated with change in hair density and diameter, respectively (standardized coefficient [β] 0.57, P<0.01; β 0.61, P<0.01). The number of prescribed oral medications was negatively associated with change in hair diameter (β -6.60, P=0.04). Limitations of this study include the single-center, retrospective design and the short followup interval. However, our findings suggest that vitamin supplementation may not lead to improved outcomes in non-scarring alopecia, thus limiting the utility of laboratory testing. Additional large-scale prospective studies are needed to improve our management of alopecia. J Drugs Dermatol. 2021;20(7):807-809. doi:10.36849/JDD.5886.
PMID: 34231996
ISSN: 1545-9616
CID: 5686742

Management of Traction Alopecia: Our Experience and a Brief Review of Current Literature Recommendations

Akintilo, Lisa; Yin, Lu; Svigos, Katerina; Kakpovbia, Efe; Shapiro, Jerry; Sicco, Kristen Lo
PMID: 33938696
ISSN: 1545-9616
CID: 5686732

Validating the optimal classification approach using International Classification of Diseases, 10th Revision codes to identify dermatology patients with acne [Letter]

Barbieri, John S; Weiner, David M; Kakpovbia, Efe; Nagler, Arielle R
PMCID:8008234
PMID: 32711090
ISSN: 1097-6787
CID: 5686722

Laboratory Testing in Telogen Effluvium

Kakpovbia, Efe; Ogbechie-Godec, Oluwatobi A; Shapiro, Jerry; Lo Sicco, Kristen I
Telogen effluvium (TE) – a common cause of non- scarring hair loss – is managed with varying clinical protocols given the paucity of evidence-based practices.
PMID: 33400415
ISSN: 1545-9616
CID: 4738752