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Corrigendum to "Distal biceps femoris avulsions: Associated injuries and neurological sequelae" [The Knee 27(6) (2020) 1874-1880]

Bloom, David A; Essilfie, Anthony A; Lott, Ariana; Alaia, Erin F; Hurley, Eoghan T; Grapperhaus, Steven; Campbell, Kirk A; Jazrawi, Laith M; Alaia, Michael J
PMID: 33472758
ISSN: 1873-5800
CID: 4760632

Distal biceps femoris avulsions: Associated injuries and neurological sequelae

Bloom, David A; Essilfie, Anthony A; Lott, Ariana; Alaia, Erin F; Hurley, Eoghan T; Grabberhaus, Steven; Campbell, Kirk A; Jazrawi, Laith M; Alaia, Michael J
BACKGROUND:The aim of this study was to describe associated injuries in cases of distal biceps femoris avulsions (DBFA) as well as the incidence of neurological injury and radiographic abnormalities of the common peroneal nerve (CPN). METHODS:A retrospective chart review was conducted of patients presenting to our office or trauma center with DBFA injuries. Demographic data was obtained as well as mechanism of injury. Assessment of concomitant injuries and presence of neurologic injury was completed via chart review and magnetic resonance imaging (MRI) review. The CPN was evaluated for signs of displacement or neuritis. RESULTS:Sixteen patients were identified (mean age-at-injury 28.6 years, 87.5% male) with DBFA. Three patients (18.8%) sustained their injuries secondary to high energy trauma while 13 (81.3%) had injuries secondary to lower energy trauma. Nine patients (56.3%) initially presented with CPN palsy. All patients presenting with CPN palsy of any kind were found to have a displaced CPN on MRI and no patient with a normal nerve course had a CPN palsy. CONCLUSIONS:This case series demonstrates a strong association between DBFA and CPN palsy as well as multi-ligamentous knee injury (MLKI). These injuries have a higher rate of CPN palsy than that typically reported for MLKI. Furthermore, these findings suggest that CPN displacement on MRI may be a clinically significant indicator of nerve injury. LOE: IV.
PMID: 33202291
ISSN: 1873-5800
CID: 4672632

Using Deep Learning to Accelerate Knee MRI at 3T: Results of an Interchangeability Study

Recht, Michael P; Zbontar, Jure; Sodickson, Daniel K; Knoll, Florian; Yakubova, Nafissa; Sriram, Anuroop; Murrell, Tullie; Defazio, Aaron; Rabbat, Michael; Rybak, Leon; Kline, Mitchell; Ciavarra, Gina; Alaia, Erin F; Samim, Mohammad; Walter, William R; Lin, Dana; Lui, Yvonne W; Muckley, Matthew; Huang, Zhengnan; Johnson, Patricia; Stern, Ruben; Zitnick, C Lawrence
OBJECTIVE:Deep Learning (DL) image reconstruction has the potential to disrupt the current state of MR imaging by significantly decreasing the time required for MR exams. Our goal was to use DL to accelerate MR imaging in order to allow a 5-minute comprehensive examination of the knee, without compromising image quality or diagnostic accuracy. METHODS:A DL model for image reconstruction using a variational network was optimized. The model was trained using dedicated multi-sequence training, in which a single reconstruction model was trained with data from multiple sequences with different contrast and orientations. Following training, data from 108 patients were retrospectively undersampled in a manner that would correspond with a net 3.49-fold acceleration of fully-sampled data acquisition and 1.88-fold acceleration compared to our standard two-fold accelerated parallel acquisition. An interchangeability study was performed, in which the ability of 6 readers to detect internal derangement of the knee was compared for the clinical and DL-accelerated images. RESULTS:The study demonstrated a high degree of interchangeability between standard and DL-accelerated images. In particular, results showed that interchanging the sequences would result in discordant clinical opinions no more than 4% of the time for any feature evaluated. Moreover, the accelerated sequence was judged by all six readers to have better quality than the clinical sequence. CONCLUSIONS:An optimized DL model allowed for acceleration of knee images which performed interchangeably with standard images for the detection of internal derangement of the knee. Importantly, readers preferred the quality of accelerated images to that of standard clinical images.
PMID: 32755163
ISSN: 1546-3141
CID: 4557132

Three-dimensional MRI Bone Models of the Glenohumeral Joint Using Deep Learning: Evaluation of Normal Anatomy and Glenoid Bone Loss

Cantarelli Rodrigues, Tatiane; Deniz, Cem M; Alaia, Erin F; Gorelik, Natalia; Babb, James S; Dublin, Jared; Gyftopoulos, Soterios
Purpose/UNASSIGNED:To use convolutional neural networks (CNNs) for fully automated MRI segmentation of the glenohumeral joint and evaluate the accuracy of three-dimensional (3D) MRI models created with this method. Materials and Methods/UNASSIGNED:Shoulder MR images of 100 patients (average age, 44 years; range, 14-80 years; 60 men) were retrospectively collected from September 2013 to August 2018. CNNs were used to develop a fully automated segmentation model for proton density-weighted images. Shoulder MR images from an additional 50 patients (mean age, 33 years; range, 16-65 years; 35 men) were retrospectively collected from May 2014 to April 2019 to create 3D MRI glenohumeral models by transfer learning using Dixon-based sequences. Two musculoskeletal radiologists performed measurements on fully and semiautomated segmented 3D MRI models to assess glenohumeral anatomy, glenoid bone loss (GBL), and their impact on treatment selection. Performance of the CNNs was evaluated using Dice similarity coefficient (DSC), sensitivity, precision, and surface-based distance measurements. Measurements were compared using matched-pairs Wilcoxon signed rank test. Results/UNASSIGNED:value range, .097-.99). Conclusion/UNASSIGNED:© RSNA, 2020.
PMCID:7529433
PMID: 33033803
ISSN: 2638-6100
CID: 4627252

Radiographic features and complications following coracoclavicular ligament reconstruction

Kennedy, Brian P; Rosenberg, Zehava Sadka; Alaia, Michael J; Samim, Mohammad; Alaia, Erin F
OBJECTIVE:To report radiographic features and complications of coracoclavicular ligament reconstruction and the association of radiographic features with symptomatology. MATERIALS AND METHODS/METHODS:Retrospective picture archiving and communication system query (1/2012-8/2018) identified subjects with prior coracoclavicular ligament reconstruction. Post-operative radiographs were reviewed with attention to the following: (1) acromioclavicular alignment, (2) coracoclavicular width, (3) distal clavicular osteolysis, (4) osseous tunnel widening, and (5) hardware complication or fracture. Medical records were reviewed to determine purpose of imaging follow-up (symptomatic versus routine). Statistical analysis determined associations between binary features and outcomes, and inter-reader agreement. RESULT/RESULTS:Review of 55 charts identified 32 subjects (23 male, 9 females; age range 24-64; imaged 1-34 months following surgery) meeting inclusion criteria. Loss of acromioclavicular reduction was the most common imaging finding (n = 25, 78%), with 76% progressing to coracoclavicular interval widening. Distal clavicular osteolysis was seen in 21 cases (66%) and was significantly associated with loss of acromioclavicular joint reduction (p = 0.032). Tunnel widening occurred in 23 patients (82%) with more than one follow-up radiograph. Six (19%) had hardware complication or fracture. No radiographic feature or complication had significant correlation with symptomatology (p values 0.071-0.721). Inter-reader agreement was moderate to substantial for coracoclavicular interval widening and hardware complication, fair to substantial for tunnel widening, and fair to moderate for loss of acromioclavicular reduction and distal clavicular osteolysis. CONCLUSION/CONCLUSIONS:Loss of acromioclavicular joint reduction, coracoclavicular interval widening, distal clavicular osteolysis, and tunnel widening are common radiographic features after coracoclavicular ligament reconstruction; however, they do not necessarily correlate with symptomatology.
PMID: 31925463
ISSN: 1432-2161
CID: 4257832

Shoulder MR Imaging and MR Arthrography Techniques: New Advances

Alaia, Erin F; Subhas, Naveen
MR imaging is the standard diagnostic modality that provides a comprehensive and accurate assessment for both osseous and soft-tissue pathologic conditions of the shoulder. This article discusses standard MR imaging and arthrography protocols used routinely in clinical practice, as well as more innovative sequences and reconstruction techniques, facilitated by the increasing availability of high-field-strength magnets and multichannel phased array surface coils and incorporation of artificial intelligence. These exciting innovations allow for a more detailed and diagnostic imaging assessment, improvements in image quality, and more rapid image acquisition.
PMID: 32241655
ISSN: 1557-9786
CID: 4371562

CROHN'S DISEASE PHENOTYPE AND ACTIVITY ARE NOT ASSOCIATED WITH SACROILIITIS IN PATIENTS UNDERGOING MAGNETIC RESONANCE ENTEROGRAPHY [Meeting Abstract]

Levine, Irving; Malik, Fardina; Castillo, Gabriel; Jaros, Brian; Alaia, Erin; Ream, Justin; Scher, Jose; Hudesman, David; Axelrad, Jordan E.
ISI:000540349503073
ISSN: 0016-5085
CID: 5524192

Anteroposterior Radiograph of the Ankle with Cross-Sectional Imaging Correlation

Lin, Dana J; Alaia, Erin F; Rossi, Ignacio Martín; Zember, Jonathan; Rosenberg, Zehava Sadka
The focus of this article is to illustrate various pathologic entities and variants, heralding disease about the ankle, based on scrutiny of AP radiographs of the ankle, with correlative findings on cross-sectional imaging. Many of these entities can only be detected on the AP ankle radiograph and, if not recognized, may lead to delayed diagnosis and persistent morbidity to the patient. However, a vigilant radiologist, equipped with the knowledge of the characteristic appearance and typical locations of the imaging findings, should be able to make the crucial initial diagnosis and surmise additional findings to be confirmed on cross-sectional imaging.
PMID: 31575401
ISSN: 1557-9786
CID: 4115642

Magnetic resonance enterography as a screening tool to detect sacroiliitis in crohn's disease: Association with clinical and endoscopic Markers of Crohn's Disease Activity [Meeting Abstract]

Malik, F; Levine, I; Castillo, G; Jaros, B; Alaia, E; Ream, J; Axelrad, J E; Hudesman, D P; Scher, J
Background/Purpose : Prevalence of sacroiliitis (SI) in Crohn's disease (CD) varies widely (range 4% -39%), depending on criteria utilized to define the disease (e.g. inflammatory back pain, plain radiographs or MRI). Sacroiliitis may remain underdiagnosed in CD patients given lack of association with clinical symptoms of back pain and CD activity. However, patients with CD often undergo magnetic resonance enterography (MRE) to assess extent, severity of small bowel CD and radiographic healing, affording clinicians the opportunity to evaluate for the presence of active and/or chronic SI. We sought to identify the prevalence of sacroiliitis in CD patients utilizing MRE and determine its relationship with CD activity, especially with concurrent biologic therapy. Methods : All CD subjects undergoing MRE between years 2014-2018 at a large IBD referral center were identified. A musculoskeletal radiologist, blinded to clinical data, reviewed all MRE exams for the presence of acute bone marrow edema (BME) lesions and chronic lesions suggestive of acute and chronic SI, respectively. A second radiologist, also blinded, assessed MRE for mucosal CD activity using validated measures. Charts were reviewed for demographics, IBD characteristics, presence of back pain, clinical and endoscopic activity of CD, and Crohn's therapies within 3 months of MRE. Comparisons were made between CD subjects with and without SI using chi-square test. Univariate and multivariate logistic regression were used to determine risk factors of SI. Results : 258 subjects with CD underwent MRE during the study period with a mean age of 35 years old, 53% (n=138) were male, and mean duration of CD at the time of MRE was 9 years. Few reported back pain (8%) and 14% had previously seen a rheumatologist. Overall, 17% (n=45) of patients had MR evidence of sacroiliitis (Table 1). Female gender, presence of back pain, and later age of CD diagnosis were associated with signs of sacroiliitis (p=0.05, p< 0.001, p=0.04 respectively; Table 2). Stricturing phenotype was associated with a lower rate of SI (7% vs. 24%; p=0.018), but inflammatory or penetrating phenotypes were not. CD location, activity as noted by clinical scores, endoscopic disease activity, or radiographic disease activity on MRE, were not associated with sacroiliitis (Table 2). On multivariable analysis, back pain was associated with the presence of sacroiliitis on MRE (OR 3.0, 95% CI 1.1-5.6; p=0.04). Concurrent CD therapy with biologics did not lower the risk of sacroiliitis. Conclusion : Although often underdiagnosed, SI is a common comorbid condition in CD. While recent history of back pain was associated with the presence of sacroiliitis visualized on MRE, no correlations were found with other clinical and endoscopic markers of CD activity. Moreover, concurrent CD therapy, especially biologics, was not associated with a lower risk of sacroiliitis on MRE. With limited clinical clues and CD characteristics to suggest sacroiliitis, gastroenterologists can utilize MRE as a screening tool to detect SI and refer CD patients to rheumatologists. Presence of SI on MRE in CD patients with back pain may help identify a subset of individuals likely to benefit from switching to therapies with proven efficacy in axial SpA
EMBASE:633059004
ISSN: 2326-5205
CID: 4633642

Stener-Like Lesions of the Superficial Medial Collateral Ligament of the Knee: MRI Features

Alaia, Erin F; Rosenberg, Zehava Sadka; Alaia, Michael J
OBJECTIVE. The purpose of this article is to describe Stener-like lesions of the superficial medial collateral ligament (sMCL) of the knee, which, to our knowledge, have not yet been reported in the radiologic literature. This lesion, defined as a distal tear with interposition of osseous or soft-tissue structures between the ligament and its tibial attachment, often requires surgical intervention. MATERIALS AND METHODS. Knee MRI examinations of grade 3 sMCL tears were identified via a search of department imaging and orthopedic case files of medial collateral ligament (MCL) tears for the period of January 2010-April 2017 using the keywords "complete MCL tear" or "near complete MCL tear." Two musculoskeletal radiologists reviewed the MRI examinations. The location of the sMCL tear, presence of a Stener-like lesion, associated ligamentous injuries, and surgical findings were recorded. RESULTS. Review of 65 knee MRI examinations identified 20 cases of distal tibial grade 3 sMCL tear. Of the distal tears, 12 (60%) were Stener-like lesions and six (30%) were borderline lesions. Of these 18 cases, 14 (78%) were associated with multiligament knee injury and nine (50%) underwent MCL repair or reconstruction. Ten of the 12 (83%) Stener-like lesions were displaced superficial to the pes anserinus and two (17%) were entrapped, one in a reverse Segond fracture and one in the femorotibial compartment. CONCLUSION. Stener-like lesions represent a high percentage of tibia-sided sMCL avulsions, are found most often with pes anserinus interposition, and are frequently associated with multiligamentous injury, suggesting high-energy trauma. MRI diagnosis is important because interposition preventing anatomic healing and potential secondary valgus instability often prompt surgical intervention.
PMID: 31461317
ISSN: 1546-3141
CID: 4054482