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Bell's Palsy After Vaccination Against Covid-19: A Systematic Review and Meta-analysis

Gordon, Alex J; Varelas, Antonios; Eytan, Danielle F
OBJECTIVE:This systematic review and meta-analysis aimed to identify studies reporting the incidence of Bell's Palsy after vaccination against coronavirus disease 2019 (Covid-19) and assess whether this incidence is greater than among the general population. DATA SOURCES/METHODS:PubMed, Embase, CINAHL, and Web of Science. REVIEW METHODS/METHODS:A systematic review was performed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Databases were searched from inception to May 9, 2022, for studies reporting the incidence of Bell's Palsy among individuals vaccinated against Covid-19 and control populations. Meta-analyses of odds ratios (ORs) were performed to compare the incidence of Bell's Palsy in these groups. RESULTS:We identified 7 studies reporting the incidence of Bell's Palsy after vaccination and among the general population, including 20,234,931 total vaccinated patients. The length of postvaccination follow-up ranged from 7 to 43 days in these studies. The incidence of Bell's Palsy was not significantly greater among vaccinated individuals (OR: 1.06; 95% confidence interval [CI]: 0.65-1.71; p = .82). Stratifying by dose, the incidence of Bell's Palsy was not significantly greater after receiving either the first dose (OR: 0.84; 95% CI: 0.47-1.49; p = .54) or second dose (OR: 1.02; 95% CI: 0.58-1.79; p = .96). CONCLUSION/CONCLUSIONS:Among the available evidence, the incidence of Bell's Palsy after vaccination against Covid-19 is comparable to that of the general unvaccinated population. Patient counseling should provide reassurance that there is no known association between Bell's Palsy and Covid-19 vaccination.
PMID: 37272720
ISSN: 1097-6817
CID: 5564002

Nerve repair and cable grafting in acute facial nerve injury

Razavi, Christopher R.; Eytan, Danielle F.; Loyo, Myriam
Facial paralysis can lead to detrimental effects on patient quality of life and impair social engagement. Accordingly, it is vital that acute injuries be triaged and managed appropriately to ensure optimal functional outcome for the patent. Here we will discuss the potential etiologies of acute facial nerve injury, particularly those that are amenable to primary repair or reconstruction with cable grafting. We will highlight options for management, the associated operative technique, and the expected recovery of function in an evidence-based fashion.
ISSN: 1043-1810
CID: 5188132

Episodic Facial Paresis-An Isolated Presenting Symptom of Multiple Sclerosis

Varelas, Antonios N; Dickstein, Leah; Eytan, Danielle F
PMID: 36757719
ISSN: 2168-619x
CID: 5462192

Equipping your facial plastic clinic for office-based procedures

Saeedi, Arman; Eytan, Danielle F.
Office-based procedures can be a fulfilling part of the facial plastic practice with the right tools, personnel, and preparation. Equipping the clinic for office-based procedures has several unique considerations that ultimately impact its success. It is important to strategize preemptively regarding what treatments will be offered and the respective equipment that will allow the safe, cost-effective, and high-quality delivery of those treatments. Most procedures in the office-based setting are cosmetic in nature and there are often overlapping treatment modalities that target similar outcomes. Patient selection and counseling is a crucial step in preparing for office-based procedures in the effort to maximize patient satisfaction. Nearly all the most common facial plastic procedures can be delivered in the office-based based setting under local anesthesia and moderate sedation, depending on the expertise of the surgeon. To enable these and other categories of treatments, there are certain expensive pieces of technology that one might consider for their office-based practice and other fundamental supplies that are necessary for almost all practices. Though the initial investment in equipment can be costly, this article also discusses more affordable alternatives or third-party sales of devices and equipment. The field of facial plastic surgery is very dynamic and having both peer and mentorship networks is invaluable in navigating some of the financial decisions discussed herein. This article also briefly covers personnel, training, and accreditation considerations.
ISSN: 2095-8811
CID: 5568472

Complications in Rhinoplasty

Eytan, Danielle F; Wang, Tom D
Rhinoplasty is widely regarded as one of the more technically challenging surgeries, owing in part to the many possible short- and long-term complications that can arise. Although severe complications are uncommon, unforeseen complications can lead to esthetic and functional compromise, patient dissatisfaction, and need for revision surgery. The rhinoplasty surgeon must be prepared to counsel patients and identify and manage the range of complications that may result from this procedure. This article reviews some of the most frequently encountered complications related to rhinoplasty and their management approaches.
PMID: 34782135
ISSN: 1558-0504
CID: 5048992

Sporotrichoid secondary syphilis [Letter]

Mazori, Daniel R; Kaplan, Laura E; Eytan, Danielle F; Heilman, Edward R
PMID: 33314047
ISSN: 1365-4632
CID: 4789942

Melanoma metastatic to the hyoid bone [Case Report]

Ryan, John F; Xie, Deborah X; Eytan, Danielle F; McCarthy, Edward F; Mandal, Rajarsi; Gourin, Christine G; Lipson, Evan J; Meyer, Christian F; Vosler, Peter S
Metastatic melanoma may be included in the differential diagnosis of hyoid masses in patients with a history of melanoma. Hyoid resection is well tolerated and of diagnostic and therapeutic benefit in patients with tumors metastatic to the hyoid bone.
PMID: 33489207
ISSN: 2050-0904
CID: 5005562

Reply to Survivors of cancer despite poor quality of care are heroes [Comment]

Bigelow, Elaine O; Blackford, Amanda L; Eytan, Danielle F; Eisele, David W; Fakhry, Carole
PMID: 32343837
ISSN: 1097-0142
CID: 5005542

Burden of comorbidities is higher among elderly survivors of oropharyngeal cancer compared with controls

Bigelow, Elaine O; Blackford, Amanda L; Eytan, Danielle F; Eisele, David W; Fakhry, Carole
BACKGROUND:The prevalence of survivors of oropharyngeal cancer (OPC) is increasing due to improved survival for individuals with human papillomavirus (HPV)-related disease. Although elderly survivors of OPC are known to have a high burden of comorbidities, to the authors' knowledge it is unknown how this compares with a similar cohort without a history of cancer. METHODS:The current retrospective, cross-sectional study included individuals with a first incident primary diagnosis of OPC from 2004 through 2011 from the Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked databases and matched controls. The baseline prevalence and subsequent incidence of comorbid conditions were identified. The association between comorbidity and overall survival was evaluated. RESULTS:A total of 2497 eligible patients with OPC were matched to 4994 noncancer controls. Baseline comorbidity was higher in cases (Charlson Comorbidity Index >0 for 48.5% of cases vs 35.8% of controls). At 5 years, cases were more likely than controls to develop comorbidities. Survivors of OPC were at high risk (≥20% cumulative prevalence by 5 years) of developing several comorbidities, including cardiovascular diseases, cerebrovascular disease, chronic obstructive pulmonary disease, and tobacco abuse, and were at moderately high risk (10%-19% cumulative prevalence) of developing other conditions including carotid artery occlusive stroke, alcohol abuse, depression, and anxiety. In both cases and controls, the presence of the majority of comorbidities either at the time of diagnosis or during the follow-up period was associated with worse survival. CONCLUSIONS:Patients with OPC have a higher comorbidity burden compared with matched controls, both at baseline and during survivorship, the majority of which are associated with decreased survival. Oncologic surveillance of survivors of OPC should include screening for highly prevalent conditions.
PMID: 31943172
ISSN: 1097-0142
CID: 5005532

Simultaneous Septal Perforation and Deviation Repair with a Chondromucosal Transposition Flap

Lu, G Nina; Eytan, Danielle F; Desai, Shaun C
Nasal septal perforations can cause issues of epistaxis, whistling, crusting, saddle deformity, and obstruction, which motivate patients to seek surgical repair. Numerous methods of septal perforation repair have been described, with surgical success rates ranging from 52% to 100%, but few studies address situations with concomitant septal deviation. In treating patients with septal perforation and deviation, both issues should be addressed for optimal outcomes. While routine septoplasty involves the removal of septal cartilage, septal perforation repair involves the addition of interposition grafts. The composite chondromucosal septal rotation flap harmoniously combines these seemingly conflicting goals as an effective and efficient technique for septal perforation repair. We present 3 patients successfully treated for their septal perforation and septal deviation concurrently with this technique.
PMID: 32500113
ISSN: 2473-974x
CID: 5005552