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Imaging Modalities in the Detection and Diagnosis of Metastatic Disease

Chapter by: Ali, S; Fenerty, Sarah; Jonnalagadda, P
in: Cancer Metastasis Through the Lymphovascular System by Leong, Stanley; et al [Eds]
pp. 283-293
ISBN: 978-3-030-93084-4
CID: 5454432

Repetitive Strain Injuries of the Upper Extremity: Imaging of Tendon Pathology and Compressive Neuropathies

Bhattacharya, Anup K; Awan, Omer A; Fenerty, Sarah; Taqi, Irfan; Jonnalagadda, Padmaja; Ling, Stephen; Ali, Sayed
Repetitive strain injuries (RSIs) encompass a broad clinicopathologic spectrum which includes discrete patterns of tissue injury involving tendons, bursae and nerves although an element of subjective symptomatology may be contributory. Upper extremity RSIs include De Quervain's tenosynovitis, intersection syndromes, epicondylitis, ulnar, and median neuritis as well as other compressive neuropathies. It is estimated that RSIs cost the US economy over $60 billion annually and while detailed clinical examination remains the diagnostic mainstay, imaging can aid in diagnosis, guide management and reduce costs.
PMID: 32826098
ISSN: 1535-6302
CID: 5449552

Bursal lipohematoma: a CT sign of full thickness rotator cuff tear in patients with proximal humerus fractures

Gupta, Yogesh Sean; Ling, Stephen; Awan, Omer; Jonnalagada, Padmaja; Fenerty, Sarah; Ali, Sayed
PURPOSE/OBJECTIVE:The main purpose of the study is to determine if the presence of a particular computed tomography (CT) imaging finding, a bursal lipohematoma, portends the presence of a concomitant rotator cuff tear (RCT) in patients with proximal humerus fractures by reviewing previous CTs. METHODS:Three hundred eighty-six CT scans were retrospectively reviewed by two board-certified radiologists to determine the presence of a proximal humerus fracture and to assess for the presence of a subacromial/subdeltoid or subcoracoid bursal hematoma. The medical record including operative documentation was then examined in the patients with proximal humerus fractures, with or without a concomitant bursal lipohematoma. RESULTS:Of the surgically managed patients, four had an intraoperative diagnosis of RCT. The preoperative CT scans of all of these patients demonstrated a bursal lipohematoma. Additionally, a non-surgically managed patient with a subacromial/subdeltoid bursal lipohematoma on CT scan was found to have a RCT on subsequent MRI. Of note, a rotator cuff tear was not documented in operative reports of patients with CT scans that were not found to contain a bursal lipohematoma. CONCLUSIONS:Bursal lipohematoma is a potentially useful preoperative CT sign of full thickness rotator cuff tear in patients with proximal humerus fractures, providing the clinician with more information in the optimization of the management approach.
PMID: 30613930
ISSN: 1438-1435
CID: 5449542

The 2015 Amtrak Philadelphia Train Derailment: After-Action Review of the Emergency Radiology Response at Temple University Health System

Bhattacharya, Anup K; Fenerty, Sarah; Awan, Omer A; Ling, Stephen; Jonnalagadda, Padmaja; Cohen, Gary; Hershey, Beverly; Ali, Sayed
PURPOSE/OBJECTIVE:The aim of this article is to assess a large tertiary care medical center's emergency radiology response after the 2015 Amtrak Philadelphia train derailment. METHODS AND MATERIALS/METHODS:A total of 55 patients with 308 total CTs and radiographs ordered within 12 hours of arrival to Temple University Health System (combining Temple University Hospital and Episcopal Hospital) emergency departments on May 12 to 13, 2015, were included in this study. A retrospective PACS and electronic medical record chart review of emergency department imaging turnaround times (TAT) during this event was completed and compared with emergency department radiology operations for the same 12-hour period throughout the preceding year. Wilcoxon's rank-sum test analysis was performed. RESULTS:A total of 308 CTs and radiographs were performed, and 91 radiologically evident injuries were observed in a total of 30 patients, with fractures (n = 51) as the most common type of injury. There were no significant differences in time from patient arrival to beginning of radiological examination (26 min; interquartile range [IQR], 11-58 min) compared with annual median (28 min; IQR, 10-131 min; P = .232). Examination completion TATs were significantly increased (35 min; IQR, 17-112 min) compared with annual median (10 min; IQR, 5-15 min; P < .001), and time required from viewing of the examination by the radiologist to the examination being marked as read was significantly decreased (17 min; IQR, 6-45 min) compared with annual median (248 min; IQR, 126-441 min; P < .001). CONCLUSIONS:The analysis highlights areas of efficiency in our response but also indicates areas for process improvement in future potential mass casualty events.
PMID: 30509460
ISSN: 1558-349x
CID: 5449532

Ulnar focal cortical indentation: a progressive, deforming variant of focal fibrocartilaginous dysplasia [Case Report]

Goldbach, Alyssa R; Zlotolow, Dan A; Fenerty, Sarah D; Rapp, Jordan; Gershkovich, Grigory; Ali, Sayed
BACKGROUND:Focal fibrocartilaginous dysplasia is a rare growth disturbance of bone resulting in deformity. In the ulna, focal fibrocartilaginous dysplasia is particularly rare, and the characteristic fibroligamentous tether can result in progressive deformity with progressive dislocation of the radial head. The fibroligamentous tether is similar in appearance and function to the Vickers ligament seen in Madelung deformity. The imaging features of ulnar focal fibrocartilaginous dysplasia include a unilateral angular deformity in the ulna with a radiolucent cortical defect and surrounding sclerosis, with secondary radial bowing or radial head dislocation. Focal fibrocartilaginous dysplasia of the ulna has been described using the term ulnar focal cortical indentation. OBJECTIVE:To review the clinical and radiologic features of four cases of ulnar focal cortical indentation occurring in pediatric patients. MATERIALS AND METHODS:We retrospectively reviewed picture archiving and communication system and electronic medical record imaging findings with surgical correlation of ulnar focal cortical indentation at two large specialty pediatric hospitals. RESULTS:Ulnar focal cortical indentation lesions typically arise in the ulnar metaphysis and result in angular forearm deformities with progressive radial deformity including radial head dislocation. Early surgical intervention prevents progression of the deformity and retains range of motion. CONCLUSION:Ulnar focal cortical indentation, although rare, is likely a progressive form of focal fibrocartilaginous dysplasia resulting in significant deformity and disability. Early recognition of the characteristic imaging features is important for early surgical intervention to preserve range of motion and prevent radial head dislocation.
PMID: 30443667
ISSN: 1432-1998
CID: 5449522

Biliary tract emergencies: What the radiologist should know

Fenerty, Sarah D.; Kunchala, Sudhir; Morgan, Matthew A.
ISSN: 0160-9963
CID: 5449592

Imaging Patterns of Injuries After the 2015 Amtrak Philadelphia Train Derailment

Bhattacharya, Anup K; Fenerty, Sarah; Awan, Omer A; Hershey, Beverly; Cohen, Gary; Jonnalagadda, Padmaja; Ling, Stephen; Ali, Sayed
OBJECTIVE:The purpose of this article is to describe the injury patterns observed in the 2015 Philadelphia Amtrak train derailment. CONCLUSION/CONCLUSIONS:Fractures accounted for most observed injuries, but uncommon and potentially serious injuries included posterior sternoclavicular dislocation and mesenteric contusion. Imaging plays a critical role in the triage of patients during mass-casualty events, and familiarity with the injury patterns associated with high-velocity unrestrained blunt force trauma will aid diagnosis in any future similar occurrence.
PMID: 29489405
ISSN: 1546-3141
CID: 5449512

Florid cemento-osseous dysplasia: review of an uncommon fibro-osseous lesion of the jaw with important clinical implications

Fenerty, Sarah; Shaw, Wei; Verma, Rahul; Syed, Ali B; Kuklani, Riya; Yang, Jie; Ali, Sayed
Florid cemento-osseous dysplasia (FCOD) is a rare, benign, multifocal fibro-osseous dysplastic process affecting tooth-bearing areas of the jaw, characterized by replacement of normal trabecular bone with osseous tissue and dense acellular cementum in a fibrous stroma. It is one clinicopathologic variant in a spectrum of related non-neoplastic fibro-osseous lesions known as cemento-osseous dysplasias (CODs), thought to arise from elements of the periodontal ligament. Diagnosis primarily relies upon radiographic and clinical findings; unnecessary biopsy should be avoided, as inoculation with oral pathogens may precipitate chronic infection in these hypovascular lesions. Appropriate management of uncomplicated FCOD consists of periodic radiographic follow-up. Accordingly, it is important that both radiologists and clinicians performing endodontic interventions possess familiarity with this entity in order to prevent misdiagnosis and inappropriate intervention, which may result in a protracted clinical course. Lesions are usually asymptomatic in the absence of infection, typically discovered on routine dental radiographs or imaging performed for unrelated indications. Radiographically, the condition typically manifests as widespread non-expansile intraosseous masses of varying internal lucency and sclerosis that surround the root apices of vital teeth or edentulous areas in the posterior jaw. While all CODs share similar microscopic features, FCOD is distinguished by its multifocal distribution, involving two or more quadrants of the maxilla and mandible, often in a bilateral symmetric fashion. The vast majority of cases are sporadic, though few exhibit an autosomal dominant familial inheritance pattern. In this pictorial review, we discuss the radiologic characteristics of this entity, pertinent clinical and histologic features, differential diagnoses, and management options.
PMID: 28194495
ISSN: 1432-2161
CID: 5449502

Test yourself: painless hand mass. Bizarre parosteal osteochondromatous proliferation (Nora lesion) of the metacarpal [Editorial]

Fenerty, Sarah; Ling, Stephen; Wang, Congli; Awan, Omer; Ali, Sayed
PMID: 27900456
ISSN: 1432-2161
CID: 5449492

Cesarean scar ectopic pregnancy [Editorial]

Fenerty, Sarah; Gupta, Sonia; Anoakar, Jordan; Patel, Tejas
ISSN: 0160-9963
CID: 5449582