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Novel Assessment of the Impact of Irritability on Physiological and Psychological Frustration Responses in Adolescents

Ferrara, Erica; Lee, Hyunjung; Stadterman Guarecuco, Jill; Somekh, Melanie R.; Hirsch, Emily; Keesey, Rodolfo; Cham, Heining; Hoyt, Lindsay Till; Roy, Amy Krain
Objective: Irritability, typically defined as a proneness to anger, particularly in response to frustration, falls at the intersection of emotion and disruptive behavior. Despite well-defined translational models, there are few convergent findings regarding the pathophysiology of irritability. Most studies utilize computer-based tasks to examine neural responses to frustration, with little work examining stress-related responding to frustration in social contexts. The present study is the first to utilize the novel Frustration Social Stressor for Adolescents (FSS-A) to examine associations between adolescent irritability and psychological and physiological responses to frustration. Method: The FSS-A was completed by a predominantly male, racially, ethnically, and socioeconomically diverse sample of 64 12- to 17-year-olds, who were originally recruited as children with varying levels of irritability. Current irritability was assessed using the Multidimensional Assessment Profiles-Temper Loss scale (MAP-TL-Youth). Adolescents rated state anger and anxiety before and after the FSS-A, and usable salivary cortisol data were collected from 43 participants. Results: Higher MAP-TL-Youth scores were associated with greater increases in anger during the FSS-A, but not increases in anxiety, or alterations in cortisol. Pre-task state anger negatively predicted the slope of the rise in cortisol observed in anticipation of the FSS-A. Conclusions: Results provide support for unique associations between adolescent irritability and anger during, and in anticipation of, frustrating social interactions. Such findings lay a foundation for future work aimed at informing physiological models and intervention targets.
ISSN: 1537-4416
CID: 5629752

A preliminary examination of key strategies, challenges, and benefits of remote learning expressed by parents during the COVID-19 pandemic

Roy, Amy K; Breaux, Rosanna; Sciberras, Emma; Patel, Pooja; Ferrara, Erica; Shroff, Delshad M; Cash, Annah R; Dvorsky, Melissa R; Langberg, Joshua M; Quach, Jon; Melvin, Glenn; Jackson, Anna; Becker, Stephen P
Among the many impacts of the Coronavirus disease (COVID-19) pandemic, one of the most dramatic was the immediate closure of in-person schooling in March/April 2020 when parents were faced with much greater responsibility in supporting their children's learning. Despite this, few studies have examined parents' own perspectives of this experience. The aims of this preliminary study were to (a) identify challenges, benefits, and useful strategies related to remote learning and (b) examine differences in findings across two countries, between parents of youth with and without attention-deficit/hyperactivity disorder (ADHD), and between parents of children and adolescents. To address these aims, parent responses to open-ended questions on the Home Adjustment to COVID-19 Scale (HACS; Becker, Breaux, et al., 2020) were examined across three studies conducted in the United States and Australia (N = 606, children: 68.5% male, ages 6-17 years). The challenges most frequently expressed by parents included the child's difficulty staying on task (23.8% of parents), lack of motivation (18.3%), remote learning factors (17.8%), and lack of social interaction (14.4%). The most frequently expressed strategy related to using routines and schedules (58.2%) and the biggest benefit was more family time (20.3%). Findings were largely consistent across countries, ADHD status, and age, with a few notable group differences. Given that the most common challenges involved child- (e.g., difficulties with staying on task and motivation), parent- (e.g., balancing remote learning with work responsibilities), and school- (e.g., remote instruction difficulties) related factors, there is a need for improved support across these systems going forward. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
PMID: 35266770
ISSN: 2578-4226
CID: 5387112

fMRI and Other Neuroimaging Methods

Chapter by: Roy, Amy Krain; Ferrara, Erica; Keesey, Rodolfo; Davis, Kaley
in: Comprehensive Clinical Psychology, Second Edition by
[S.l.] : Elsevier, 2022
pp. 62-82
ISBN: 9780128186978
CID: 5460562

Coronary plaque ulceration documented at sequential angiography and confirmed by optical coherence tomography in a patient with recurrent acute coronary syndrome [Case Report]

Ferlini, Marco; Potenza, Antonella; Ferrara, Erica; Ferrario, Maurizio; Repetto, Alessandra; Marinoni, Barbara; Visconti, Luigi O; Bramucci, Ezio
: A 51-year-old man was hospitalized for recurrence of acute coronary syndrome after few months. Coronary angiography during first hospitalization showed no significant coronary stenosis, while the second time, right coronary artery presented an expansion at the proximal segment. Optical coherence tomography documented a long fibroatheroma with an ulceration and residual white thrombus.
PMID: 25111774
ISSN: 1558-2035
CID: 3409202