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Breast abscess as initial manifestation of extensive DCIS: a rare presentation and literature review

Ranjbar, Suedeh; Marks, Douglas K; Natoli, Noel B; Sarmiento, Ruth; Flieder, Andrea; Rossmer, Irene E
PMID: 32914488
ISSN: 1524-4741
CID: 4590242

Collision metastases of two ipsilateral primary breast carcinomas to an axillary lymph node [Meeting Abstract]

Buyuk, Arzu; Turi, George K.; Flieder, Andrea
ISSN: 0893-3952
CID: 3276382

Mucosa-associated lymphoid tissue lymphoma of the stomach: long term outcome after local treatment

Fung CY; Grossbard ML; Linggood RM; Younger J; Flieder A; Harris NL; Graeme-Cook F
BACKGROUND: Although antibiotic therapy is emerging as effective initial treatment for patients with gastric lymphoma of mucosa-associated lymphoid tissue (MALT), there is a subset of patients for whom antibiotics are ineffective or inappropriate. Surgical resection can be curative, but total gastrectomy may be required for the eradication of all disease. To identify the optimal nonantibiotic therapy for early stage gastric MALT lymphoma, the authors retrospectively evaluated the Massachusetts General Hospital experience with gastric MALT lymphoma. METHODS: Disease patterns and treatment outcomes were retrospectively analyzed in data from 21 consecutive patients with gastric MALT lymphoma who were treated between 1978 and 1995 at the Massachusetts General Hospital. RESULTS: Sixteen patients were Stage IE, and 5 were in higher stages. Treatment consisted of resection with or without radiation or chemotherapy (14 patients), radiation alone (4 patients), or radiation plus chemotherapy (2 patients). Thirteen Stage IE patients received local therapy only. The 10-year actuarial relapse free survival rate for Stage IE patients was 93%, with 1 relapse among 15 treated patients. Because the patient who relapsed was treated successfully with chemotherapy, the 10-year cancer free survival was 100%. Overall survival for Stage IE patients was 93% at 5 years and 58% at 10 years, with no deaths from lymphoma. CONCLUSIONS: These data indicate that a high probability of long term remission can be achieved with only local treatment of patients with Stage I gastric MALT lymphoma. Preliminary results suggest that radiation therapy is well tolerated and effective and may well be the optimal nonantibiotic treatment for patients with localized gastric MALT lymphoma
PMID: 9921968
ISSN: 0008-543x
CID: 33130

Endocrine mucin-producing sweat gland carcinoma: a cutaneous neoplasm analogous to solid papillary carcinoma of breast [Case Report]

Flieder A; Koerner FC; Pilch BZ; Maluf HM
We describe two cases of a distinctive in situ and invasive cutaneous adnexal neoplasm occurring in the eyelid. Mucinous carcinoma represented the invasive portion of the tumor in one case, whereas the other infiltrated in small solid nests. The in situ component is identical to the recently described solid papillary carcinoma of the breast (endocrine ductal carcinoma in situ). Both tumors produced intra- and extracellular mucin, exhibited endocrine differentiation by immunohistochemistry and ultrastructural analysis, and were positive for estrogen and progesterone receptors
PMID: 9414195
ISSN: 0147-5185
CID: 33131