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Defragmentation of low grade day 3 embryos resulted in sustained reduction in fragmentation, but did not improve compaction or blastulation rates

Keltz, Martin; Fritz, Rani; Gonzales, Eric; Ozensoy, Serhan; Skorupski, Josh; Stein, Daniel
In a prospective randomized fashion, this study evaluated embryo development in vitro after defragmentation versus assisted hatching alone of low grade day 3 embryos. Although a sustained decrease in day 5 fragmentation was observed in the defragmented group versus the assisted hatching only group, no difference in compaction rates or blastula formation rates were appreciated.
PMID: 20403590
ISSN: 1556-5653
CID: 3803552

Extended embryo culture and natural fertilization do not protect against chromosomal errors: Aneuploidy rates in spontaneous abortions (SAB) are similar for day 3 (D3) and day 5 (D5) embryo transfers and are unrelated to intracytoplasmic sperm injection (ICSI) [Meeting Abstract]

Keegan, DA; Krey, LC; Fritz, R; Noyes, N
ISI:000232114601111
ISSN: 0015-0282
CID: 59567