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Aesthetic Use of BoNT: Options and Outcomes

Gendler, Ellen; Nagler, Arielle
There are a multitude of uses for BoNT in the aesthetic realm. Efficacy has been shown in softening glabellar creases, crows feet, forehead rhytides, and in correcting facial asymmetries, including mild eyelid ptosis. Facial shape can be altered through injections of BoNT into masseter, and smiles can be altered with BoNT. Clinical examples of the above will be shown, as well as adverse outcomes with inaccurate injection techniques.
PMID: 26368007
ISSN: 1879-3150
CID: 1779152

Development and validation of a 6-point grading scale in patients undergoing correction of nasolabial folds with a collagen implant

Monheit, Gary D; Gendler, Ellen C; Poff, Bradley; Fleming, Laura; Bachtell, Nathan; Garcia, Emily; Burkholder, David
BACKGROUND: Various scoring techniques prone to subjective interpretation have been used to evaluate soft tissue augmentation of nasolabial folds (NLFs). OBJECTIVE: To design and validate a reliable wrinkle assessment scoring scale. MATERIALS AND METHODS: Six photographed wrinkles of varying severity were electronically copied onto the same facial image to become a 6-point grading scale (GGS). A pilot training program (13 investigators) determined reliability, and a 12-week multicenter survey study validated the GGS scoring method. RESULTS: Pilot study inter- and intrarater scoring reliability were high (weighted kappa scores of 0.85 and 0.86, respectively). Seventy-five percent of survey investigators and independent review panel (IRP) members considered a GGS score difference of 0.5 to be a minimally perceivable difference. Interrater weighted kappa scores were 0.91 for the IRP and 0.80 for investigators. Intrarater agreements after repeat testing were 0.91 and 0.89, respectively. The baseline "live" assessment GGS mean score was 3.34, and the baseline blinded photographic assessment GGS mean score was 2.00 for the IRP and 2.16 for the investigators. CONCLUSIONS: The GGS is a reproducible method of grading the severity of NLF wrinkles. Treatment effectiveness of a dermal filler can be reliably evaluated using the GGS by comparing "live" assessments with the standard GGS photographic panel.
PMID: 20969658
ISSN: 1524-4725
CID: 2128012

Hyaluronic acid skin derivatives

Chapter by: Anolik, R; Gendler, E
in: Augmentation Fillers by
pp. 17-28
ISBN: 9780511674853
CID: 2483392

Treatment of periorbital hyperpigmentation

Gendler, Ellen C
Periorbital hyperpigmentation is a generally benign, extremely common condition that is notoriously resistant to treatment. According to the author, the key to successful treatment is determining the primary cause and complying with maintenance and preventive regimens. A multimodal approach may be required, encompassing topical bleaching agents, chemical peels, laser therapy, and/or surgery.
PMID: 19338869
ISSN: 1527-330x
CID: 2128022

Hyaluronic acid for soft-tissue augmentation

Frank P; Gendler E
PMID: 11248862
ISSN: 0094-1298
CID: 21235

Aging skin

Chapter by: Frank P; Gendler E
in: Current dermatologic diagnosis & treatment by Freedberg IM; Sanchez MR [Eds]
Philadelphia : Lippincott Williams & Wilkins, 2001
pp. 10-11
ISBN: 0781735319
CID: 3662

A practical approach to the use of retinoids in aging skin

Gendler EC
PMID: 9703137
ISSN: 0190-9622
CID: 57152

Topical treatment of the aging face

Gendler EC
This article discusses the various over-the-counter and prescription products available to help improve sun-damaged skin, as well as superficial peeling agents. Practical suggestions for treating patients are given
PMID: 9348457
ISSN: 0733-8635
CID: 12199

Resurfacing with topical agents

Lewis AB; Gendler EC
Evaluation of the aging face reveals many changes such as lentigines, coarseness, senile purpura, and fine lines that can be blamed primarily on photoaging. There are many topical preparations that are now being used or are under investigation for facial rejuvenation. These include retinold creams, alpha-hydroxy acids, Ethocyn (Chantal Skin Care Corp, Los Angeles, CA), topical vitamins, and topical hormonal treatments. There has been substantial media attention devoted to these 'antiaging' cures but there is a lack of scientific evidence to support some of these claims. After review of these agents, a practical approach to the patient requesting younger-looking skin is presented
PMID: 8948531
ISSN: 1085-5629
CID: 16420

Alstroemeria. A new and potent allergen for florists [Case Report]

Adams RM; Daily AD; Brancaccio RR; Dhillon IP; Gendler EC
Alstroemeria (Peruvian or Inca lily) has found particular favor because of its beauty and durability. However, it may induce a dermatitis so severe that workers have to change jobs. The dermatitis is chronic, with fissuring at the tips of the fingers bilaterally. Itching is often a less prominent symptom. Preventative measures are of little benefit, and many floral shops are vanishing the plant
PMID: 2137401
ISSN: 0733-8635
CID: 16206