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Clinical and Optical Coherence Tomography Correlation of Vascular Conditions Treated With a Novel, Variable-Sequenced, Long-Pulsed, 532 and 1,064 nm Laser With Cryogen Spray Cooling

Wang, Jordan V; Bajaj, Shirin; Himeles, Jaclyn R; Geronemus, Roy G
BACKGROUND:Patients frequently seek laser treatment for vascular conditions. More recently, a novel 532 and 1,064 nm laser was developed to offer greater flexibility. OBJECTIVE:A prospective clinical trial evaluated the safety and efficacy of a novel, variable-sequenced, long-pulsed, 532 and 1,064 nm laser with cryogen spray cooling (DermaV, Lutronic, South Korea). MATERIALS AND METHODS/METHODS:Subjects with vascular conditions were enrolled for laser treatments. Clinical evaluations and optical coherence tomography (OCT) imaging were performed. RESULTS:Thirteen subjects were enrolled. The mean age was 51.3 years, and 92.3% were women. Fitzpatrick skin types I-IV were included. Treatment indications included broken blood vessels, rosacea, port-wine birthmark, and spider angioma. For physician investigator grading, all subjects were graded as improved at both 30-day and 90-day follow-up. Blinded photographic review by 3 independent, blinded physicians had a mean of 89.7% of cases selected correctly with at least 2 of 3 in agreement for 100.0% of cases. Optical coherence tomography imaging showed significant reductions in vessel density ( p = .018) and diameter ( p = .003) of the superficial vascular plexus. No serious adverse events occurred. CONCLUSION/CONCLUSIONS:A novel, variable-sequenced, long-pulsed, 532 and 1,064 nm laser with cryogen spray cooling can safely and effectively improve vascular conditions and lesions as determined by both clinical and OCT evaluation.
PMID: 38085090
ISSN: 1524-4725
CID: 5589172

Ideas and Innovations: Complete Resolution of Surgical Marking Tattoo Postminimal Access Cranial Suspension Facelift Using a High-power Picosecond Laser [Case Report]

Nemcevic, Andjela; Bajaj, Shirin; Geronemus, Roy
Traumatic tattoos can occur when foreign pigment particles are embedded within the dermis, sometimes resulting as traumatic events. Traditional treatment modalities, including surgical excision, cryosurgery, electrosurgery, dermabrasion, CO2 lasers, and argon lasers, have limitations such as nonselectivity for pigment and risks of scarring and discoloration. We present the case of a patient who developed a postoperative tattoo after a minimal access cranial suspension facelift procedure that subsequently completely resolved after treatment with the high-powered 1064-nm picosecond laser. The patient achieved complete resolution of the postoperative tattoo after five laser treatments without adverse events or recurrence of pigmentation on follow-up. High-powered 1064-nm picosecond laser can serve as a fast, safe, and effective modality that in our clinic has become the first-line treatment for traumatic tattoos, and in our patient led to high satisfaction.
PMID: 38515554
ISSN: 2169-7574
CID: 5640782

Potential Role of Tranexamine Acid and Nonablative Fractional Resurfacing in Managing Facial Hyperpigmentation

Hashemi, David A; Wang, Jordan V; Geronemus, Roy G
PMID: 38231520
ISSN: 2168-6084
CID: 5628812

Outcomes of Cutaneous Surgery for Nonmelanoma Skin Cancer in Patients with Different Fitzpatrick Skin Types: A Nationwide, Multicenter, Prospective Study

Nadir, Umer; Yi, Michael D; Koza, Eric; Shi, Victoria J; Dave, Loma; Hisham, Farhana Ikmal; Maisel-Campbell, Amanda; Lin, Katherine A; Ibrahim, Sarah A; Kang, Bianca Y; Anvery, Noor; Dirr, McKenzie A; Christensen, Rachel E; Riley, Julia M; Kundu, Roopal V; Aylward, Juliet L; Bari, Omar; Bhatti, Hamza; Bolotin, Diana; Cherpelis, Basil S; Cohen, Joel L; Condon, Sean; Farhang, Sheila; Firoz, Bahar; Garrett, Algin B; Geronemus, Roy G; Golda, Nicholas J; Humphreys, Tatyana R; Hurst, Eva A; Jacobson, Oren H; Jiang, S Brian; Karia, Pritesh S; Kimyai-Asadi, Arash; Kouba, David J; Council, M Laurin; Le, Marilyn; MacFarlane, Deborah F; Maher, Ian A; Miller, Stanley J; Moioli, Eduardo K; Morrow, Meghan; Neckman, Julia; Peterson, Samuel R; Poblete-Lopez, Christine; Prather, Chad L; Ranario, Jennifer S; Rubin, Ashley G; Swanson, Andrew M; Urban, Christopher; Xu, Y Gloria; Pearlman, Ross; Cahn, Brian A; ,; Yoo, Simon; Harikumar, Vishnu; Weil, Alexandra; Schaeffer, Matthew; Iyengar, Sanjana; Poon, Emily; Alam, Murad
PMID: 38296200
ISSN: 1097-6787
CID: 5627152

How We Do It: Erbium-Doped Yttrium Aluminum Garnet Laser for the Treatment of Postsurgical Trapdoor Deformity

Himeles, Jaclyn Rosenthal; Bajaj, Shirin; Bernstein, Leonard J; Shelton, Ronald; Geronemus, Roy
PMID: 37962148
ISSN: 1524-4725
CID: 5611192

The big picture: Terminology in laser medicine [Letter]

Sodha, Pooja; Wang, Jordan V; Geronemus, Roy G; Friedman, Paul M
PMID: 38254328
ISSN: 1096-9101
CID: 5624752

Safety and Effectiveness of Fractional Ablative CO2 Laser-Assisted Delivery of Topical Poly-l-Lactic Acid for Rhytides and Scars

Steuer, Alexa B; Bajaj, Shirin; Wang, Jordan V; Geronemus, Roy G
PMID: 38288943
ISSN: 1524-4725
CID: 5627452

The big picture: Terminology in laser medicine

Sodha, Pooja; Wang, Jordan V.; Geronemus, Roy G.; Friedman, Paul M.
ISSN: 0196-8092
CID: 5629442

Laser Removal of Eyeliner and Eyebrow Tattoos: Chart Review, Experiences, and Learnings

Kream, Elizabeth; Jairath, Neil; Bajaj, Shirin; Orbuch, David; Wang, Jordan V; Geronemus, Roy G
BACKGROUND/UNASSIGNED:A retrospective chart review for the laser treatment of eyeliner and eyebrow tattoos and a discussion of treatment experiences can better inform physicians. METHODS/UNASSIGNED:A retrospective chart review was performed over five years with patients who had eyeliner and/or eyebrow tattoos and had laser removal. RESULTS/UNASSIGNED:Overall, 76 patients were treated. Mean age was 47 years, and 98.7 percent were women. Fitzpatrick Skin Types I-VI were represented. Of all cases, 55.3 percent included eyebrows, 43.4 percent eyelids, and 1.3 percent both. There was a mean of 2.8 treatments. Common colors included black (73.7%), black/red (7.9%), black/orange (5.3%), black/yellow (3.9%), and red (3.9%). Most cases were treated with 755nm picosecond laser or high peak-powered 532nm/1064nm picosecond laser. After initial treatment, 26.3 percent of cases involved unmasking of colors, such as red, orange, yellow, green, and blue, which were not previously visualized. There were no documented adverse events related to scarring, hypotrichosis, necrosis, and burns. CONCLUSION/UNASSIGNED:Laser removal of eyeliner and eyebrow tattoos can be safe and effective. There should be consideration for eye and hair protection, pain control, and pigment unmasking.
PMID: 38076654
ISSN: 1941-2789
CID: 5589552

Largest comparative analysis: Novel large spot size 595 nm, high-energy, pulsed dye laser reduces number of treatments for improvement of adult and pediatric port wine birthmarks [Case Report]

Sodha, Pooja; Wang, Jordan V; Aboul-Fettouh, Nader; Martin, Katherine; Geronemus, Roy G; Friedman, Paul M
OBJECTIVE:Port wine birthmarks (PWBs) are vascular malformations affecting 0.3%-0.5% of newborns with the tendency to persist into adulthood without adequate treatment of the heterogenous ectatic vessels. This study compares treatment outcomes and parameters of the prior generation pulsed dye laser (PPDL) and the larger spot novel generation pulsed dye laser (NPDL) to establish whether a larger spot size laser provides greater clearance with fewer treatments. METHODS:One hundred and sixty patients were treated with either the PPDL (80 patients) and NPDL (80 patients) with retrospective review of age, body site, laser treatment parameters, number of treatments, and improvement following laser therapy. RESULTS:with pulse durations of 0.45-6 ms. Fifty percent improvement was seen with 8.8 PPDL treatments compared to 4.3 NPDL treatments (p ≤ 0.01) with no significant difference in overall mean improvement between both devices at the chosen parameters. Multiple regression analysis showed that device type, not age or lesion location, was the only statistically significant independent variable to affect the endpoint of at least 50% improvement of the lesion. CONCLUSIONS:Use of the larger spot NPDL is associated with achieving 50% improvement with fewer treatments.
PMID: 37293831
ISSN: 1096-9101
CID: 5594052