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Dynamic Optical Coherence Tomography of Cutaneous Blood Vessels in Melasma and Vessel Response to Oral Tranexamic Acid [Case Report]

Pomerantz, Hyemin; Christman, Mitalee P; Bloom, Bradley S; Lederhandler, Margo; Feng, Hao; Holmes, Jon; Geronemus, Roy G
BACKGROUND AND OBJECTIVES/OBJECTIVE:Melasma may be related to aberrant blood vessels, but there has been no report on the utility of dynamic optical coherence tomography (D-OCT) in studying vessel characteristics in melasma. We studied the characteristics of cutaneous blood vessels in melasma and the effects of oral tranexamic acid (TXA) with D-OCT. STUDY DESIGN/MATERIALS AND METHODS/METHODS:Six patients with moderate to severe melasma had a D-OCT scanning of the areas on the face affected by melasma and not affected by it. Three of them had scans within 3 months after starting oral TXA and at a follow-up visit. Blood flow at different depths of the skin and vessel diameter were compared between the melasma and normal skin. For those taking oral TXA, we compared the percent change of blood flow and diameter between the melasma and normal skin. RESULTS:Dermal blood flow and vessel diameter were greater in the melasma skin than in the normal skin. Oral TXA reduced dermal blood flow in both the melasma and normal skin, but the reduction was more dramatic in the lesional melasma skin. CONCLUSIONS:D-OCT findings that (i) dermal blood vessels in melasma are increased in size and flow and (ii) oral TXA reduced the vessel size and flow, providing evidence supporting the relationship between melasma and cutaneous blood vessels. D-OCT may be utilized in measuring response to treatments targeting melasma. Lasers Surg. Med. © 2020 Wiley Periodicals LLC.
PMID: 33161588
ISSN: 1096-9101
CID: 4662962

Safety and Utility of a Novel Nitrous Oxide Delivery System in Cosmetic Surgery: A National Survey of Physician Practices

Wang, Jordan V; Munavalli, Girish S; Pozner, Jason; Geronemus, Roy G
PMID: 34313636
ISSN: 1524-4725
CID: 4949222

Experiences and Perspectives of Patients With Striae: A Survey With Treatment Implications

Wang, Jordan V; Kream, Elizabeth J; Munavalli, Girish S; Geronemus, Roy G
PMID: 34313640
ISSN: 1524-4725
CID: 4949232

Do-It-Yourself Cosmetic Injectables in Dermatology: High-Risk, No Reward

Wang, Jordan V; Saedi, Nazanin; Geronemus, Roy G
PMID: 33165063
ISSN: 1524-4725
CID: 4664782

Case Series of Corneal Eye Shield Application for Laser Treatment of Periocular Port-Wine Stains in Infancy

Lederhandler, Margo; Jeon, Hana; Pomerantz, Hyemin; Bernstein, Leonard J; Geronemus, Roy G
PMID: 32738422
ISSN: 1097-6787
CID: 4553442

Growing role for arnica in cosmetic dermatology: Lose the bruise

Sherban, Alexander; Wang, Jordan V; Geronemus, Roy G
This commentary examines the utility of arnica in cosmetic dermatology. For many years, arnica has been used to reduce the morbidity associated with various procedures, including surgeries and treatments with laser and other energy-based devices. Arnica is a traditional homeopathic remedy that can reduce post-procedural edema and bruising. Although it has been used clinically by many physicians and is widely and readily available to patients, the available data is limited and often conflicting. We reviewed the relevant information on arnica and offer our own insights into its use in order to shed more light on its peri-procedural utility.
PMID: 33930256
ISSN: 1473-2165
CID: 4853772

Successful treatment of facial port-wine birthmark in a premature infant [Case Report]

Fidai, Chelsea; Geronemus, Roy G
PMID: 34136622
ISSN: 2352-5126
CID: 4917562

Comparison of injectable filler locations in men and women: An age-matched case analysis

Wang, Jordan V; Valiga, Alexander; Albornoz, Christian A; Geronemus, Roy G
In recent years, the popularity of fillers has risen significantly. Traditionally, women have undergone the vast majority of cosmetic procedures, but men have steadily shown increasing interest. Recently, significant research has been dedicated to understanding the anatomic differences between male and female facial structures and their clinical aesthetic implications, especially for filler placement. In order to compare actual treatment data to evidence these discussions, we randomly selected 100 cases each of men and women, who were matched for age, and documented their filler placement locations. Facial heat maps were constructed to provide readers with visual evidence. Male cheeks were more inferiomedial, while female cheeks were more superolateral. Men had more jawline fillers, while women had more lip and perioral fillers. Our study builds upon gender-specific considerations. It is important for physicians to be knowledgeable regarding the unique approaches to fillers in men and women in order to deliver more effective, tailored, and high-quality care.
PMID: 34129719
ISSN: 1473-2165
CID: 4911622

Real-World Experience With Oral Tranexamic Acid and Lasers for Pigmentary Disorders: A 5-Year Safety Review

Wang, Jordan V; Valiga, Alexander; Geronemus, Roy G
PMID: 34115690
ISSN: 1524-4725
CID: 4900402

Single-Session Treatment With Botulinum Toxin and 755-nm Picosecond Laser With Diffractive Lens Array: A 5-Year Safety Review

Wang, Jordan V; Albornoz, Christian A; Anolik, Robert; Geronemus, Roy G
PMID: 34115677
ISSN: 1524-4725
CID: 4900382