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Fractional Ablative Laser-Assisted Delivery of Topical Poly-L-lactic Acid: A 2.5-Year Safety Review

Wang, Jordan V; Ugonabo, Nkemjika; Geronemus, Roy G
PMID: 34889214
ISSN: 1524-4725
CID: 5110452

Treating pediatric port-wine stains in aesthetics

Lederhandler, Margo H; Pomerantz, Hyemin; Orbuch, David; Geronemus, Roy G
A port-wine stain (PWS) is a vascular birthmark present in 0.3% to 0.5% of newborns. If untreated, this erythematous patch will grow proportionally with the child to thicken and darken with age. PWSs have implications for the child's quality of life for many years, with cosmetic, medical, and psychosocial disability. Controversy exists in many aspects surrounding laser treatment of these birthmarks in the pediatric population. We have reviewed the clinical features as well as the historic and current laser treatment of PWS. We have also examined the current hot topics of debate surrounding the treatment of PWS in the pediatric population. These controversies include the patient age of treatment initiation, the long-term psychologic impact, the use of general anesthesia, the application of eye shields, and alternative treatments for recalcitrant PWS. We have concluded with a discussion on the future directions of management and treatment.
PMID: 35190059
ISSN: 1879-1131
CID: 5167902

Efficacy and Safety of High-Intensity, High-Frequency, Parallel Ultrasound Beams for Fine Lines and Wrinkles

Wang, Jordan V; Ferzli, Georgina; Jeon, Hana; Geronemus, Roy G; Kauvar, Arielle
BACKGROUND:Ultrasound energy has been used for cutaneous rejuvenation, including treatment of fine lines and wrinkles. Ultrasound waves of high intensity can induce thermal injury in the dermis, which causes tissue coagulation and remodeling. OBJECTIVE:To examine the safety and utility of a novel ultrasound device that uses high-intensity, high-frequency, parallel ultrasound beams to improve fine lines and wrinkles of the face and neck. MATERIALS AND METHODS:A prospective, multicenter, clinical study investigated the utility of this novel ultrasound device to improve fine lines and wrinkles. Sixty subjects were enrolled for single treatment to the face and neck. RESULTS:Fifty-eight subjects completed the study. The mean age was 58 years, and 87.9% were women. Fitzpatrick skin Types I to VI were represented. Assessments compared 12-week follow-up with baseline. Two blinded reviewers agreed in identifying pretreatment and post-treatment photographs for 78% of subjects. There was significant improvement of 1 to 3 Fitzpatrick Wrinkle and Elastosis Scale units in 86% of subjects. For investigator global improvement scores, 88% of subjects had improvement. Overall, 72% of subjects noted improvement, and the majority were satisfied. There were no device-related adverse events. CONCLUSION:Treatment with a novel ultrasound device that uses high-intensity, high-frequency, parallel ultrasound beams safely improved the clinical appearance of fine lines and wrinkles of the face and neck.
PMID: 34417390
ISSN: 1524-4725
CID: 5082782

Safety and Utility of a Novel Nitrous Oxide Delivery System in Cosmetic Surgery: A National Survey of Physician Practices

Wang, Jordan V; Munavalli, Girish S; Pozner, Jason; Geronemus, Roy G
PMID: 34313636
ISSN: 1524-4725
CID: 4949222

Experiences and Perspectives of Patients With Striae: A Survey With Treatment Implications

Wang, Jordan V; Kream, Elizabeth J; Munavalli, Girish S; Geronemus, Roy G
PMID: 34313640
ISSN: 1524-4725
CID: 4949232

Combining Low-Power Fractional Diode Laser With Injectable Neurotoxin and Filler: Safety of Treatment Regimen Over 6 Years

Wang, Jordan V; Kushner, Carolyn; Anolik, Robert; Geronemus, Roy G
PMID: 34334618
ISSN: 1524-4725
CID: 5060922

Assessment of Treatment Tolerance and Parental Perspective of Outpatient Pulsed-Dye Laser Treatment for Port-Wine Birthmark without General Anesthesia in Infants and Toddlers

Feng, Hao; Materne, Grace; Ghalili, Sabrina; Lederhandler, Margo; Pomerantz, Hyemin; Christman, Mitalee; Bernstein, Leonard J; Geronemus, Roy G
PMID: 33010319
ISSN: 1097-6787
CID: 4626412

Combining cosmetic injectables with low-energy, low-density 1927 nm fractional thulium fiber laser: A 2.5-year examination on the safety of same-day treatments

Wang, Jordan V; Akintilo, Lisa; Geronemus, Roy G
Combining laser treatments with cosmetic injectables can offer synergistic benefit, increased convenience for both patients and physicians, and lessened overall patient downtime. Although paired treatments can be effective, there remain theoretical concerns that this may add new risks. Theoretical risks of combining laser treatment with neurotoxin injections include unintentional spread of the neurotoxin, which may result in eyelid ptosis and muscle weakness. Potential risks with soft-tissue fillers include unexpected loss of filler volume, necrosis, burn, and product migration. This retrospective chart review of single-session, same-day facial treatments using a low-energy, low-density 1927 nm fractional thulium fiber laser and cosmetic injectables found no adverse events related to this combination approach. This is important safety information that can offer reassurance to physicians using this clinical approach.
PMID: 33742533
ISSN: 1473-2165
CID: 4821982

Cost Savings of In-Office Pulsed Dye Laser Treatment of Port-Wine Birthmarks Without General Anesthesia

Wang, Jordan V; Albornoz, Christian A; Geronemus, Roy G
PMID: 33941728
ISSN: 1524-4725
CID: 4866092

Single-Session Treatment With Botulinum Toxin and 755-nm Picosecond Laser With Diffractive Lens Array: A 5-Year Safety Review

Wang, Jordan V; Albornoz, Christian A; Anolik, Robert; Geronemus, Roy G
PMID: 34115677
ISSN: 1524-4725
CID: 4900382