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MIFEPRISTONE TREATMENT FOR MILD AUTONOMOUS CORTISOL SECRETION DUE TO ADRENAL ADENOMAS: A PILOT STUDY
Belokovskaya, Regina; Ravikumar, Aarti; Arumugam, Dushyanthy; Izadmehr, Sudeh; Goddard, Gillian M; Geer, Eliza B; Levine, Alice C
PMID: 31070948
ISSN: 1530-891x
CID: 4055142
Adrenal mild hypercortisolism
Goddard, Gillian M; Ravikumar, Aarti; Levine, Alice C
Adrenal incidentalomas have become detected more often as the use of abdominal imaging has increased. Up to one-third of these may be secreting low levels of cortisol, known as mild hypercortisolism or subclinical Cushing syndrome. These low levels of cortisol have been found to be associated with an increased in the metabolic syndrome, osteoporosis, cardiovascular events, and mortality. This article discusses in detail the epidemiology, diagnosis, clinical associations, and treatment options of mild hypercortisolism.
PMID: 26038206
ISSN: 1558-4410
CID: 3481232
Workup and Medical Management of Primary Aldosteronism during Pregnancy: A Case Report and Review of the Literature [Meeting Abstract]
Eschler, Deirdre Cocks; Ravikumar, Aarti; Goddard, Gillian M.; Krakoff, Lawrence; Levine, Alice C.
ISI:000209805106276
ISSN: 0163-769x
CID: 3482392
Pitfalls of Using ACTH Alone in the Localization of Cushing's Syndrome [Meeting Abstract]
Goddard, Gillian M.; Babic, Nikolina; Levine, Alice C.; Post, Kalmon D.; Geer, Eliza B.
ISI:000209805106055
ISSN: 0163-769x
CID: 3482382
Common infectious agents prevalence in antiphospholipid syndrome
Zinger, H; Sherer, Y; Goddard, G; Berkun, Y; Barzilai, O; Agmon-Levin, N; Ram, M; Blank, M; Tincani, A; Rozman, B; Cervera, R; Shoenfeld, Y
Antiphospholipid syndrome is characterized by thrombosis and pregnancy loss. Infections are generally associated with autoimmune diseases, but in the setting of antiphospholipid syndrome this link has been suggested as having a pathogenic role. In this study, 98 patients with antiphospholipid syndrome were screened for antibodies directed to several infectious agents. The main finding in this study is the significantly higher prevalence of IgM antibodies to toxoplasma and rubella. This novel finding suggests that these infections might be associated with antiphospholipid syndrome. As autoimmune diseases and, in particular, antiphospholipid syndrome are associated with infections, mainly the catastrophic type of the syndrome, this finding implies that a current infection with these agents, i.e. toxoplasma and rubella, might either be related to the pathogenesis of antiphospholipid syndrome or alternatively to its manifestations.
PMID: 19880561
ISSN: 1477-0962
CID: 6014022
Regulation of cytosolic malate dehydrogenase expression by extracellular DNA [Meeting Abstract]
Goddard, Gillian M.; Cook, Jason; Teixeira, Avelino; Hanss, Basil
ISI:000245708705053
ISSN: 0892-6638
CID: 3482402