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164


PER ORAL ENDOSCOPIC MYOTOMY (POEM) FOR ACHALASIA: LONG TERM OUTCOMES FROM A LARGE PROSPECTIVE SINGLE-CENTER US SERIES [Meeting Abstract]

Stavropoulos, Stavros N.; Modayil, Rani J.; Zhang, Xiaocen; Khodorskiy, Dmitriy O.; Taylor, Sharon I.; Kollarus, Maria M.; Brathwaite, Collin E.; Widmer, Jessica L.; Grendell, James H.
ISI:000435509900429
ISSN: 0016-5107
CID: 3514242

A LARGE SINGLE CENTER ENDOSCOPIC SUBMUCOSAL DISSECTION (ESD) EXPERIENCE IN A WESTERN SETTING [Meeting Abstract]

Stavropoulos, Stavros N.; Khodorskiy, Dmitriy O.; Ly, Erin K.; Modayil, Rani J.; Nithyanand, Sagarika; Bhumi, Sriya; DeMaria, Matthew J.; Zhang, Xiaocen; Widmer, Jessica L.; Grendell, James H.
ISI:000434248200393
ISSN: 0016-5107
CID: 3522492

PERORAL CHOLANGIOSCOPY WITH GASTROSCOPES: SEE MORE, DO MORE! [Meeting Abstract]

Widmer, Jessica L.; Modayil, Rani J.; Friedel, David; Allendorf, John; Grendell, James H.; Stavropoulos, Stavros N.
ISI:000434248200310
ISSN: 0016-5107
CID: 3522472

Per-oral endoscopic myotomy in patients with or without prior Heller's myotomy: comparing long-term outcomes in a large U.S. single-center cohort (with videos)

Zhang, Xiaocen; Modayil, Rani J; Friedel, David; Gurram, Krishna C; Brathwaite, Collin E; Taylor, Sharon I; Kollarus, Maria M; Modayil, Sony; Halwan, Bhawna; Grendell, James H; Stavropoulos, Stavros N
BACKGROUND AND AIMS/OBJECTIVE:Heller's myotomy (HM) is one of the most effective treatments for esophageal achalasia. However, failures do exist, and the success rate tends to decrease with time. The efficacy of rescue treatments for patients with failed HM is limited. A few small-scale studies have reported outcomes of per-oral endoscopic myotomy (POEM) in these patients. We conducted this study to systematically assess feasibility, safety, and efficacy of POEM on patients who have had HM. METHODS:Patients at least 3 months out from POEM were selected from our prospective database: 318 consecutive POEMs performed from October 2009 to October 2016. The efficacy and safety of POEM were compared between the 46 patients with prior HM and the remaining 272 patients. RESULTS:Patients with prior HM had longer disease history, more advanced disease, more type I and less type II achalasia, lower before-POEM Eckardt scores, and lower before-POEM lower esophageal sphincter (LES) pressure (all P < .01). Procedure parameters and follow-up results (clinical success rate, Eckardt score, LES pressure, GERD score, esophagitis, and pH testing) showed no significant difference between the 2 groups. For the 46 HM-POEM patients, no clinically significant perioperative adverse events occurred. Their overall clinical success rate (Eckardt score ≤3 and no other treatment needed) was 95.7% at a median follow-up of 28 months. CONCLUSION/CONCLUSIONS:POEM as a rescue treatment for patients with achalasia who failed HM is feasible, safe, and highly effective. It should be the treatment of choice in managing these challenging cases at centers with a high level of experience with POEM.
PMID: 29122601
ISSN: 1097-6779
CID: 3035592

Corneal abrasion following anaesthesia for non-ocular surgical procedures: A case-controlled study

Carniciu, Anais L; Fazzari, Melissa J; Tabibian, Pauline; Batta, Priti; Gentile, Ronald C; Grendell, James H; Braithwaite, Collin E; Barzideh, Nazanin
The aim of this study was to identify risk factors associated with perioperative corneal abrasion at a single hospital in Mineola, New York (United States). A chart review was conducted of patients with perioperative corneal abrasion following non-ocular surgery and age-matched controls between June 2011 and November 2013. An age-stratified logistic regression model evaluated the association between corneal abrasion and potentially predisposing variables. The adjusted odds of a corneal abrasion occurring were 4.6 times greater for patients having surgery for ≥ 3 hours (p=0.001) and 3.6 times greater for patients with pre-existing ocular disease (p=0.02). Gender, diabetes status, surgical procedure or position were not found to be associated with the occurrence of a corneal abrasion. Corneal abrasions were associated with longer procedures and history of pre-existing ocular disease. No significant association between body positioning or surgical site and perioperative corneal abrasion was found. The study concludes that a longer duration of surgical procedure and pre-existing ocular disease are risk factors for perioperative corneal abrasion.
PMID: 29328794
ISSN: 1750-4589
CID: 3453342

Endoscopic Tunnel-Assisted Muscle Biopsy to Diagnose Esophageal Metastasis of Urothelial Malignancy: A First of Its Kind! [Meeting Abstract]

Ali, Mohammad F.; Modayil, Rani; Donovan, Virginia; Grendell, James; Stavropoulos, Stavros
ISI:000439259004070
ISSN: 0002-9270
CID: 3522632

Prospective, Randomized Comparison of 3 Endoscopic Submucosal Dissection (ESD) Knives in an Acute Porcine Model [Meeting Abstract]

Stavropoulos, Stavros; Ghevariya, Vishal; Cho, Jaehoon; DeJesus, Dolorita; Katsogridakis, Ioannis; Gupta, Mala; Rodriguez, Katherine; Barkan, Alexander; Angelos, George; Iqbal, Shahzad; Grendell, James; Grendell, James H. H.
ISI:000439259002064
ISSN: 0002-9270
CID: 3522552

Use of Peroral Endoscopic Myotomy (POEM) in Pediatric Patients as a Primary or Rescue Therapy for Achalasia [Meeting Abstract]

Stavropoulos, Stavros N.; Sosulski, Amanda B.; Modayil, Rani J.; Gurram, Krishna C.; Brathwaite, Collin E.; Coren, Charles V.; Boinpally, Harika; Grendell, James H.
ISI:000403087400615
ISSN: 0016-5107
CID: 3514142

Per Oral Endoscopic Myotomy (POEM) for Achalasia: Long-Term Outcomes Beyond 2 Years From a Large Prospective Single-Center Us Series [Meeting Abstract]

Stavropoulos, Stavros N.; Modayil, Rani J.; Brathwaite, Collin E.; Sy, Alexander; Ali, Mohammad F.; Taylor, Sharon I.; Halwan, Bhawna; Gurram, Krishna C.; Kollarus, Maria M.; Grendell, James H.
ISI:000403087400046
ISSN: 0016-5107
CID: 3508472

Peroral Endoscopic Myotomy (Poem) in Patients With or Without Prior Heller Myotomy: Comparing Long-Term Outcomes in a Large Us Single Center Cohort [Meeting Abstract]

Stavropoulos, Stavros N.; Zhang, Xiaocen; Modayil, Rani J.; Gurram, Krishna C.; Brathwaite, Collin E.; Taylor, Sharon I.; Halwan, Bhawna; Kollarus, Maria M.; Grendell, James H.
ISI:000403087401544
ISSN: 0016-5107
CID: 3508482