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Profound leukemia cutis in a patient with relapsed T-cell acute lymphoblastic leukemia [Case Report]

Nohria, Ambika; Criscito, Maressa C; Weston, Gillian K; Kim, Randie H; Lo Sicco, Kristen I; Femia, Alisa N; Hejazi, Emily Z; Milam, Emily C
PMID: 34815993
ISSN: 2352-5126
CID: 5063622

Cutaneous Lupus Erythematosus: An Update on Pathogenesis, Diagnosis and Treatment

Hejazi, Emily Z; Werth, Victoria P
Cutaneous lupus erythematosus (CLE) includes a broad range of dermatologic manifestations, which may or may not be associated with systemic disease. Recent studies in this area continue to shape our understanding of this disease and treatment options. Epidemiologic studies have found an incidence of CLE of 4.30 per 100,000, which approaches similar analysis for systemic lupus erythematosus (SLE). Although there have been extensive efforts to define SLE, the classification of CLE and its subgroups remains a challenge. Currently, diagnosis relies on clinical and laboratory findings as well as skin histology. The Cutaneous Lupus Area and Severity Index (CLASI) is a validated measure of disease activity and damage. CLE pathogenesis is multifactorial and includes genetic contributions as well as effects of ultraviolet (UV) light. Immune dysregulation and aberrant cell signaling pathways through cytokine cascades are also implicated. Patient education and avoidance of triggers are key to disease prevention. Antimalarials and topical steroids continue to be the standard of care; however, immunosuppressants, thalidomide analogs and monoclonal antibodies are possible systemic therapies for the treatment of recalcitrant disease.
PMID: 26872954
ISSN: 1175-0561
CID: 2045112

Pruritic, Pink Scaling Plaques on the Face and Trunk. Pemphigus erythematosus [Case Report]

Pritchett, Ellen N; Hejazi, Emily; Cusack, Carrie Ann
PMID: 26267852
ISSN: 2168-6084
CID: 4482442

An acute linear pruritic eruption following allergic contact dermatitis

Sommer, Lacy L; Hejazi, Emily Z; Heymann, Warren R
PMID: 25489384
ISSN: 1941-2789
CID: 4482432