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Hogan, John I; Duerr, Ralf; Heguy, Adriana
PMID: 36346103
ISSN: 1537-6591
CID: 5357182

Remdesivir resistance in transplant recipients with persistent COVID-19

Hogan, John I; Duerr, Ralf; Dimartino, Dacia; Marier, Christian; Hochman, Sarah E; Mehta, Sapna; Wang, Guiqing; Heguy, Adriana
New mutations conferring resistance to SARS-CoV-2 therapeutics have important clinical implications. We describe the first cases of an independently acquired V792I RNA-dependent RNA polymerase mutation developing in renal transplant recipients after remdesivir exposure. Our work underscores the need for augmented efforts to identify concerning mutations and address their clinical implications.
PMID: 36156117
ISSN: 1537-6591
CID: 5333962