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Transpostion muscle flaps for infected infrainguinal vascular grafts : a case report and review of the literature

Imam, M; Kim, R; Ger, R
ISSN: 0161-1372
CID: 5347452

Association of Meckel's diverticulum and arteriovenous malformations of the ileum

Imam, M; Nadjari, H
ISSN: n/a
CID: 5347462

Modification of the expression of adenosine 3',5'-cyclic monophosphate-induced differentiated functions in neuroblastoma cells by beta-carotene and D-alpha-tocopheryl succinate

Prasad, K N; Kentroti, S; Edwards-Prasad, J; Vernadakis, A; Imam, M; Carvalho, E; Kumar, S
OBJECTIVE:The role of beta-carotene and vitamin E in modifying the effect of cell differentiating agent has not been studied. This study has investigated the effects of beta-carotene and d-alpha-tocopheryl succinate (alpha-TS) on adenosine 3',5'-cyclic monophosphate (cAMP) induced differentiated functions in murine neuroblastoma cells (NBP2) in culture. METHODS:Prostaglandin E1 (PGE1), a stimulator of adenylate cyclase, and 4-(3-butoxy-4-methoxy-benzyl)-2-imidazolidinone (R020-1724), an inhibitor of cyclic nucleotide phosphodiesterase, were used to induce differentiation in NB cells. RESULTS:Both beta-carotene and alpha-TS markedly enhanced the level of morphologic differentiation (neurite formation) induced by both PGE1 and R020-1724. However, beta-carotene and alpha-TS by themselves were ineffective. These vitamins increased tyrosine hydroxylase (TH) activity. However, beta-carotene did not significantly affect PGE1- and R020-1724-stimulated rise in TH activity. alpha-TS at a higher concentration inhibited PGE1- and R020-1724-stimulated increase in TH activity. None of the above treatments affected basal choline acetyltransferase (ChAT) activity. beta-carotene and alpha-TS caused a transient increase in cAMP level, and they also enhanced the effect of PGE1 and R020-1724 on cAMP level in a transient manner. CONCLUSION/CONCLUSIONS:These results suggest that beta-carotene and alpha-TS modify the effects of cAMP stimulating agents on differentiation of NB cells in culture.
PMID: 7915734
ISSN: 0731-5724
CID: 5347432

Intestinal obstruction by jejunal diverticular enteroliths

Kalambe, B; Imam, M; Parikh, S; Patankar, C; Sina, R
ISSN: 0524-0182
CID: 5347442