Try a new search

Format these results:

Searched for:

person:jas231

in-biosketch:true

Total Results:

109


Re-examining melanoma secondary prevention and the role of skin self-examination

Ingrassia, Jenne P; Adotama, Prince; Stein, Jennifer A; Polsky, David
PMID: 37385450
ISSN: 1097-6787
CID: 5540512

Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing

Kashani-Sabet, Mohammed; Leachman, Sancy A; Stein, Jennifer A; Arbiser, Jack L; Berry, Elizabeth G; Celebi, Julide T; Curiel-Lewandrowski, Clara; Ferris, Laura K; Grant-Kels, Jane M; Grossman, Douglas; Kulkarni, Rajan P; Marchetti, Michael A; Nelson, Kelly C; Polsky, David; Seiverling, Elizabeth V; Swetter, Susan M; Tsao, Hensin; Verdieck-Devlaeminck, Alexandra; Wei, Maria L; Bar, Anna; Bartlett, Edmund K; Bolognia, Jean L; Bowles, Tawnya L; Cha, Kelly B; Chu, Emily Y; Hartman, Rebecca I; Hawryluk, Elena B; Jampel, Risa M; Karapetyan, Lilit; Kheterpal, Meenal; Lawson, David H; Leming, Philip D; Liebman, Tracey N; Ming, Michael E; Sahni, Debjani; Savory, Stephanie A; Shaikh, Saba S; Sober, Arthur J; Sondak, Vernon K; Spaccarelli, Natalie; Usatine, Richard P; Venna, Suraj; Kirkwood, John M
IMPORTANCE:Therapy for advanced melanoma has transformed during the past decade, but early detection and prognostic assessment of cutaneous melanoma (CM) remain paramount goals. Best practices for screening and use of pigmented lesion evaluation tools and gene expression profile (GEP) testing in CM remain to be defined. OBJECTIVE:To provide consensus recommendations on optimal screening practices and prebiopsy diagnostic, postbiopsy diagnostic, and prognostic assessment of CM. EVIDENCE REVIEW:Case scenarios were interrogated using a modified Delphi consensus method. Melanoma panelists (n = 60) were invited to vote on hypothetical scenarios via an emailed survey (n = 42), which was followed by a consensus conference (n = 51) that reviewed the literature and the rationale for survey answers. Panelists participated in a follow-up survey for final recommendations on the scenarios (n = 45). FINDINGS:The panelists reached consensus (≥70% agreement) in supporting a risk-stratified approach to melanoma screening in clinical settings and public screening events, screening personnel recommendations (self/partner, primary care provider, general dermatologist, and pigmented lesion expert), screening intervals, and acceptable appointment wait times. Participants also reached consensus that visual and dermoscopic examination are sufficient for evaluation and follow-up of melanocytic skin lesions deemed innocuous. The panelists reached consensus on interpreting reflectance confocal microscopy and some but not all results from epidermal tape stripping, but they did not reach consensus on use of certain pigmented lesion evaluation tools, such as electrical impedance spectroscopy. Regarding GEP scores, the panelists reached consensus that a low-risk prognostic GEP score should not outweigh concerning histologic features when selecting patients to undergo sentinel lymph node biopsy but did not reach consensus on imaging recommendations in the setting of a high-risk prognostic GEP score and low-risk histology and/or negative nodal status. CONCLUSIONS AND RELEVANCE:For this consensus statement, panelists reached consensus on aspects of a risk-stratified approach to melanoma screening and follow-up as well as use of visual examination and dermoscopy. These findings support a practical approach to diagnosing and evaluating CM. Panelists did not reach consensus on a clearly defined role for GEP testing in clinical decision-making, citing the need for additional studies to establish the clinical use of existing GEP assays.
PMID: 36920356
ISSN: 2168-6084
CID: 5502422

Expert Consensus Statement on Proficiency Standards for Dermoscopy Education in Primary Care

Tran, Tiffaney; Cyr, Peggy R; Verdieck, Alex; Lu, Miranda D; Ahrns, Hadjh T; Berry, Elizabeth G; Bowen, William; Braun, Ralph P; Cusick-Lewis, Joshua M; Doan, Hung Q; Donohue, Valerie L; Erlich, Deborah R; Ferris, Laura K; Harkemanne, Evelyne; Hartman, Rebecca I; Holt, James; Jaimes, Natalia; Joslin, Timothy A; Kabaeva, Zhyldyz; Liebman, Tracey N; Ludzik, Joanna; Marghoob, Ashfaq A; Simpson, Isac; Stein, Jennifer A; Stulberg, Daniel L; Tromme, Isabelle; Turnquist, Matthew J; Usatine, Richard P; Walker, Alison M; Walker, Bryan L; West, Robert F; Wilson, Megan L; Witkowski, Alexander; Wu, Dominic J; Seiverling, Elizabeth V; Nelson, Kelly C
BACKGROUND:Primary care providers (PCPs) frequently address dermatologic concerns and perform skin examinations during clinical encounters. For PCPs who evaluate concerning skin lesions, dermoscopy (a noninvasive skin visualization technique) has been shown to increase the sensitivity for skin cancer diagnosis compared with unassisted clinical examinations. Because no formal consensus existed on the fundamental knowledge and skills that PCPs should have with respect to dermoscopy for skin cancer detection, the objective of this study was to develop an expert consensus statement on proficiency standards for PCPs learning or using dermoscopy. METHODS:A 2-phase modified Delphi method was used to develop 2 proficiency standards. In the study's first phase, a focus group of PCPs and dermatologists generated a list of dermoscopic diagnoses and associated features. In the second phase, a larger panel evaluated the proposed list and determined whether each diagnosis was reflective of a foundational or intermediate proficiency or neither. RESULTS:Of the 35 initial panelists, 5 PCPs were lost to follow-up or withdrew; 30 completed the fifth and last round. The final consensus-based list contained 39 dermoscopic diagnoses and associated features. CONCLUSIONS:This consensus statement will inform the development of PCP-targeted dermoscopy training initiatives designed to support early cancer detection.
PMID: 36759132
ISSN: 1558-7118
CID: 5467152

Instructional Strategies to Enhance Dermoscopic Image Interpretation Education: a Review of the Literature

Tran, Tiffaney; Ternov, Niels K; Weber, Jochen; Barata, Catarina; Berry, Elizabeth G; Doan, Hung Q; Marghoob, Ashfaq A; Seiverling, Elizabeth V; Sinclair, Shelly; Stein, Jennifer A; Stoos, Elizabeth R; Tolsgaard, Martin G; Wolfensperger, Maya; Braun, Ralph P; Nelson, Kelly C
INTRODUCTION/UNASSIGNED:In image interpretation education, many educators have shifted away from traditional methods that involve passive instruction and fragmented learning to interactive ones that promote active engagement and integrated knowledge. By training pattern recognition skills in an effective manner, these interactive approaches provide a promising direction for dermoscopy education. OBJECTIVES/UNASSIGNED:A narrative review of the literature was performed to probe emerging directions in medical image interpretation education that may support dermoscopy education. This article represents the second of a two-part review series. METHODS/UNASSIGNED:To promote innovation in dermoscopy education, the International Skin Imaging Collaborative (ISIC) assembled an Education Working Group that comprises international dermoscopy experts and educational scientists. Based on a preliminary literature review and their experiences as educators, the group developed and refined a list of innovative approaches through multiple rounds of discussion and feedback. For each approach, literature searches were performed for relevant articles. RESULTS/UNASSIGNED:Through a consensus-based approach, the group identified a number of theory-based approaches, as discussed in the first part of this series. The group also acknowledged the role of motivation, metacognition, and early failures in optimizing the learning process. Other promising teaching tools included gamification, social media, and perceptual and adaptive learning modules (PALMs). CONCLUSIONS/UNASSIGNED:Over the years, many dermoscopy educators may have intuitively adopted these instructional strategies in response to learner feedback, personal observations, and changes in the learning environment. For dermoscopy training, PALMs may be especially valuable in that they provide immediate feedback and adapt the training schedule to the individual's performance.
PMCID:9681169
PMID: 36534542
ISSN: 2160-9381
CID: 5394962

To the Editor: Patient and County-Level Factors Associated with Late Stage Merkel Cell Carcinoma at Diagnosis

Shah, Payal; Polsky, David; Shao, Yongzhao; Stein, Jennifer; Liebman, Tracey N
PMID: 35537549
ISSN: 1523-1747
CID: 5214322

Delays in melanoma presentation during the COVID-19 pandemic: A nationwide multi-institutional cohort study

Trepanowski, Nicole; Chang, Michael S; Zhou, Guohai; Ahmad, Maham; Berry, Elizabeth G; Bui, Katherine; Butler, William H; Chu, Emily Y; Curiel-Lewandrowski, Clara; Dellalana, Laura E; Ellis, Darrel L; Freeman, S Caleb; Gorrepati, Pavane L; Grossman, Douglas; Gyurdzhyan, Samvel; Kanetsky, Peter A; Ong King, Amber Loren; Kolla, Avani M; Lian, Christine G; Lin, Jennifer Y; Liu, Vincent; Lowenthal, Annie; McCoy, Kelly N; Munjal, Ananya; Myrdal, Caitlyn N; Perkins, Sara; Powers, Jennifer G; Rauck, Corinne; Smart, Tristan C; Stein, Jennifer A; Venna, Suraj; Walsh, Madalyn E; Wang, Jennifer Y; Leachman, Sancy A; Swetter, Susan M; Hartman, Rebecca I
PMCID:9212700
PMID: 35738513
ISSN: 1097-6787
CID: 5282122

A Health Equity Framework to Address Racial and Ethnic Disparities in Melanoma

Kolla, Avani M; Seixas, Azizi; Adotama, Prince; Foster, Victoria; Kwon, Simona; Li, Vivienne; Lee, Ann Y; Stein, Jennifer A; Polsky, David
PMID: 35970385
ISSN: 1097-6787
CID: 5299802

Theory-Based Approaches to Support Dermoscopic Image Interpretation Education: A Review of the Literature

Tran, Tiffaney; Ternov, Niels K.; Weber, Jochen; Barata, Catarina; Berry, Elizabeth G.; Doan, Hung Q.; Marghoob, Ashfaq A.; Seiverling, Elizabeth V.; Sinclair, Shelly; Stein, Jennifer A.; Stoos, Elizabeth R.; Tolsgaard, Martin G.; Wolfensperger, Maya; Braun, Ralph P.; Nelson, Kelly C.
Introduction: Efficient interpretation of dermoscopic images relies on pattern recognition, and the development of expert-level proficiency typically requires extensive training and years of practice. While traditional methods of transferring knowledge have proven effective, technological advances may significantly improve upon these strategies and better equip dermoscopy learners with the pattern recognition skills required for real-world practice. Objectives: A narrative review of the literature was performed to explore emerging directions in medical image interpretation education that may enhance dermoscopy education. This article represents the first of a two-part review series on this topic. Methods: To promote innovation in dermoscopy education, the International Skin Imaging Collaborative (ISIC) assembled a 12-member Education Working Group that comprises international dermoscopy experts and educational scientists. Based on a preliminary literature review and their experiences as educators, the group developed and refined a list of innovative approaches through multiple rounds of discussion and feedback. For each approach, literature searches were performed for relevant articles. Results: Through a consensus-based approach, the group identified a number of emerging directions in image interpretation education. The following theory-based approaches will be discussed in this first part: whole-task learning, microlearning, perceptual learning, and adaptive learning. Conclusions: Compared to traditional methods, these theory-based approaches may enhance dermoscopy education by making learning more engaging and interactive and reducing the amount of time required to develop expert-level pattern recognition skills. Further exploration is needed to determine how these approaches can be seamlessly and successfully integrated to optimize dermoscopy education.
SCOPUS:85143280413
ISSN: 2160-9381
CID: 5392832

Impact of Electrical Impedance Spectroscopy on Clinician Confidence and Diagnostic Accuracy in Evaluating Melanocytic Skin Lesions Suspicious for Melanoma: A Pilot Study

Kolla, Avani; Fried, Lauren; Shah, Payal; Liebman, Tracey; Stein, Jennifer; Polsky, David
Introduction: Nevisense is a non-invasive device that measures electrical impedance spectroscopy (EIS) of individual skin lesions to aid in the diagnosis of melanoma. While EIS has demonstrated high sensitivity in diagnosing melanoma, its impact on a clinician"™s diagnostic confi dence remains unknown. Objective: To conduct a pilot study to evaluate whether clinician diagnostic confidence, sensitivity, specificity and accuracy can be increased by adding EIS measurement scores to clinical and dermoscopic images of lesions clinically suspicious for melanoma. Methods: Three pigmented lesions specialists and three 4th year medical students completed an online survey to evaluate 34 melanocytic lesions suspicious for melanoma. For each lesion, participants provided their diagnosis, biopsy recommendation, and confidence in diagnosing a lesion as benign or malignant based on history and clinical and dermoscopic images, and again after receiving an EIS score. Results: Addition of EIS scores increased mean biopsy sensitivity for melanoma/severely dysplastic nevi from 70% to 84% (p =.014) and mean diagnostic accuracy from 74% to 86% (p =.005). Mean diagnostic confidence increased for all histopathologic categories for both students and dermatologists (all p <.05). Conclusions: In this pilot study, EIS increased novice and expert diagnosticians"™ confidence regarding dermoscopically equivocal melanocytic lesions. Further studies are needed to explore how EIS can help clinicians reassure patients regarding the management of clinically dysplastic melanocytic nevi.
SCOPUS:85136242839
ISSN: 2574-1624
CID: 5311802

Melanoma surveillance for high-risk patients via telemedicine: Examination of real-world data from an integrated store-and-forward total body photography and dermoscopy service

Tan, Andrea; Greenwald, Elizabeth; Bajaj, Shirin; Belen, Debbie; Sheridan, Taylor; Stein, Jennifer A; Liebman, Tracey N; Bowling, Adrian; Polsky, David
PMID: 33515626
ISSN: 1097-6787
CID: 4775632