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Reply to Piperata, Bottio, Avesani, and Gerosa [Letter]

Williams, David M; Masuno, Kiriko; Kanchuger, Marc S; Hisamoto, Kazuhiro
PMID: 33586240
ISSN: 1540-8191
CID: 4786432

Innominate artery dissection due to selective cerebral antegrade perfusion [Case Report]

Williams, David M; Masuno, Kiriko; Kanchuger, Marc S; Hisamoto, Kazuhiro
We present the first case of successfully treated innominate artery dissection as a complication of selective cerebral antegrade perfusion during reoperative aortic valve and hemiarch replacements. Innominate artery dissection was suspected based on unilateral decreases in the right radial arterial pressure and right cerebral oximetry value. Intraoperative ultrasonography demonstrated minimal flow in the right internal carotid. A right aortoaxillary bypass graft was performed leading to immediate improvements in the right radial arterial pressure waveform and right cerebral oximetry. The patient was discharged neurologically intact on postoperative day six.
PMID: 33403684
ISSN: 1540-8191
CID: 4738882

Intraoperative Anaphylaxis to Chlorhexidine During LVAD and Transplant Surgery

Zhou, Eric; Parikh, Purvi S; Kanchuger, Marc S; Balsam, Leora B
PMID: 29859756
ISSN: 1532-8422
CID: 3144242

Variation in local institutional review board evaluations of a multicenter patient safety study

Thompson, David A; Kass, Nancy; Holzmueller, Christine; Marsteller, Jill A; Martinez, Elizabeth A; Gurses, Ayse P; Kanchuger, Marc; Schwann, Nanette; Gibson, Charles S; Bauer, Laura; Pronovost, Peter J
Several highly visible quality improvement (QI) projects led to controversy over their ethical oversight, attracting attention from institutional review boards (IRBs) and the Office for Human Research Protection. While QI research has increased dramatically, there is limited empirical evidence regarding how multiple IRBs review the same study. This paper describes the variations in local IRB reviews for the same a multicenter QI study. The study, entitled "Locating Errors through Networked Surveillance", used multiple data collection methods to identify patient safety risks in cardiovascular operating room services. This study involved 2-day site visits to 5 hospitals by the research team to observe cardiac surgery procedures and interview staff regarding clinical practice and hazards. Surveys were self-administered. The IRB process varied widely across the 5 hospitals. Reviews ranged from full committee review and approval with verbal consent required from patients and operating room staff, to an IRB determining the study exempt from review and participant consent. The time to IRB approval ranged from 6 weeks to 6 months. This variation suggests there is wide interpretation of the Federal regulations put in place to guide IRBs. The adoption of uniformity would not only reduce inefficiencies but also attenuate the perceived arbitrary nature of current IRB review processes that often inappropriately influence hypothesis-generation and study design.
PMID: 22060010
ISSN: 1062-2551
CID: 302892

Case report: separation from cardiopulmonary bypass with a rigid bronchoscope airway after hemoptysis and bronchial impaction with clot

Neuburger, Peter J; Galloway, Aubrey C; Zervos, Michael D; Kanchuger, Marc S
Hemoptysis after cardiopulmonary bypass (CPB) occasionally occurs, and has varying clinical significance based upon amount of bleeding. Hemoptysis resulting in a clot and airway obstruction is an extremely rare event found almost exclusively in the intensive care unit. We describe a unique case of hemoptysis resulting in bronchial impaction from a clot requiring an emergent return to CPB during valve replacement surgery. We used a rigid bronchoscope, without an endotracheal tube, to facilitate airway patency in a patient with diffuse airway bleeding after bronchial disimpaction to separate from CPB
PMID: 22034489
ISSN: 1526-7598
CID: 147685

Pro: all off-pump coronary artery bypass graft surgeries should include intraoperative transesophageal echocardiography assessment

Morganstern, Jill; Kanchuger, Marc
PMID: 18662644
ISSN: 1532-8422
CID: 91435

Intraoperative failure of pericardial mitral valve requiring emergent reoperation minutes after replacement [Case Report]

Thukral, Mamta; Kanchuger, Marc
PMID: 17289489
ISSN: 1053-0770
CID: 302902

Glycemic control for cardiovascular surgery patients: An integrated approach [Meeting Abstract]

Yu, PJ; Schwartz, CF; Kanchuger, MS; Kent, M; Keller, R; Lohan-Mullens, M; Brassil, M; Seltzer, TF; Radford, MJ
ISSN: 0009-7322
CID: 108085

Comparison of image quality between a narrow caliber transesophageal echocardiographic probe and the standard size probe during intraoperative evaluation

Reynolds, Harmony R; Spevack, Daniel M; Shah, Alan; Applebaum, Robert M; Kanchuger, Mark; Tunick, Paul A; Kronzon, Itzhak
BACKGROUND: Transesophageal echocardiography (TEE) has become an integral part of the evaluation and monitoring of patients during cardiac operation. Until recently, the smallest TEE probe with multiplane imaging measured 13 mm in diameter. This size is now standard for adult TEE probes. Recently, a new TEE probe has become available (MiniMulti TEE probe, Philips Medical Systems, Andover, Mass), which has a diameter of 8 mm. Although using a smaller probe is attractive, the quality of images it generates when used in adults has not yet been examined. OBJECTIVE: The purpose of this study was to compare TEE studies done with both probes. METHODS: After informed consent was obtained, full intraoperative TEE studies were performed in 20 patients with a small pediatric probe. The study was then repeated using a standard adult probe. The studies were read in random order by two experienced echocardiographers blinded to probe used. For each study, 18 anatomic cardiac structures and 5 Doppler patterns were subjectively graded as excellent (1), good (2), fair (3), or poor (4) in quality. The average score for each structure or Doppler profile was computed for each probe. RESULTS: The average score for all findings was lower (better) for the adult TEE probe (1.4 +/- 0.4 vs 1.7 +/- 0.4; P =.003). When each finding was compared separately, several cardiac structures (left ventricle [LV], pericardium, right ventricle [RV], interatrial septum, left atrium, left atrial appendage, mitral valve, aortic valve) had better scores with the adult probe, and the differences for the LV and RV were larger than those for the other findings (LV scores differed by 0.7, P =.0004; RV scores differed by 0.5, P =.01). There was no significant difference between probes when evaluating venous structures (coronary sinus, superior vena cava, pulmonary vein), the thoracic aorta, or the right atrium or tricuspid valve. In addition, Doppler patterns were not significantly different with the two probes. There were two findings that were missed with the small probe and seen with the adult probe (one aortic plaque and one left atrial appendage thrombus). CONCLUSIONS: In the adult, the larger probe provides better images, particularly of the RV and LV. In addition, important findings may be missed with the smaller probe. However, if the adult probe cannot be passed, the pediatric probe is a reasonable alternative
PMID: 15452470
ISSN: 0894-7317
CID: 45390

Comparison of a small (pediatric) transesophageal echocardiography probe with a standard (adult) probe [Meeting Abstract]

Reynolds, HR; Spevack, DM; Shah, A; Applebaum, RM; Kanchuger, M; Tunick, PA; Kronzon, I
ISSN: 0735-1097
CID: 42452