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Beyond Avoidance: Advanced Therapies for Contact Dermatitis

Yin, Lu; Ungar, Benjamin; Guttman-Yassky, Emma; Cohen, David E; Karagounis, Theodora K
Contact dermatitis (CD) is a common and burdensome condition divided into irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD). Treatment relies on accurate diagnosis and identification of the trigger, as definitive treatment is irritant/allergen avoidance. However, avoidance is not always possible, such as if the patient is reacting to a necessary medical device, if the trigger is integral to the patient's occupation, or if avoidance is practically untenable. In these cases, treatment is particularly challenging, especially as the literature on treatments in this clinical scenario is limited. Additionally, CD has a complex pathophysiology that varies according to trigger type, leading to variable treatment efficacy. This article reviews the current literature on treatments for CD with a focus on treatments when trigger avoidance is not feasible.
PMID: 38821440
ISSN: 2213-2201
CID: 5664052

Comparison of comorbidities and adverse events in dermatology and rheumatology patients prescribed tofacitinib: A retrospective analysis

Needle, Carli D; Klein, Elizabeth J; Gjonaj, Jessica; Nohria, Ambika; Karim, Maria; Liu, Lynn; Shah, Jinal; Betensky, Rebecca A; Garshick, Michael; Lo Sicco, Kristen; Karagounis, Theodora K
PMID: 38008410
ISSN: 1097-6787
CID: 5617552

A 30-Year-Old Man With Finger Pain and Swelling [Case Report]

Li-Geng, Tony; Sartori, Daniel J; Shoucri, Sherif; Meehan, Shane A; Karagounis, Theodora K
PMID: 37607354
ISSN: 1537-6591
CID: 5598412

Occupational Hand Dermatitis

Karagounis, Theodora K; Cohen, David E
PURPOSE OF REVIEW/OBJECTIVE:Occupational hand dermatitis is a common work-related disorder of the skin. Prevention and management of this disease is critical to improving workers' quality of life and for occupation-specific retention. RECENT FINDINGS/RESULTS:This is a critical review of the current literature on occupational hand dermatitis. Occupational dermatitis continues to have a high prevalence among workers although the overall incidence may be slowly decreasing. Irritant contact dermatitis due to wet work exposure is the most common cause of occupational hand dermatitis. Healthcare workers, hairdressers, and metal workers are at particularly high risk for this disease. While some prevention programs have been ineffective in mitigating occupational hand dermatitis, other more resource-intensive initiatives may have benefit. Continued research is needed on ways to manage wet work exposures and on scalable, effective prevention programs for occupational hand dermatitis. The spectrum of culprit contact allergens continues to evolve, and vigilance for potential occupation-specific allergens remains important.
PMID: 36749448
ISSN: 1534-6315
CID: 5426882

A Woman With Painful Digital Ulcers

Karagounis, Theodora; Belmont, H Michael; Caplan, Avrom S
PMID: 35344026
ISSN: 1538-3598
CID: 5200912

Chronic tongue pain and alopecia

Karagounis, Theodora; Yan, Di; Oza, Vikash; Kim, Randie
PMID: 34931369
ISSN: 1525-1470
CID: 5108762

Response to "Patient preference for cellulitis treatment: at-home care is preferred to hospital-based treatment" [Letter]

Shaw, Katharina S; Karagounis, Theodora K; Yin, Lu; Gibbon, Grace; Betensky, Rebecca A; Lo Sicco, Kristen I; Femia, Alisa N
PMID: 32777319
ISSN: 1097-6787
CID: 4556092

Viral Venereal Diseases of the Skin

Karagounis, Theodora K; Pomeranz, Miriam K
Viral venereal diseases remain difficult to treat. Human papilloma virus (HPV) and herpes simplex virus (HSV) are two common viral venereal diseases. HPV infections are characterized by anogenital warts and less commonly by premalignant or malignant lesions. HSV infections classically present as grouped vesicles on an erythematous base with associated burning or pain; however, immunosuppressed patients may have atypical presentations with nodular or ulcerative lesions. This review discusses the epidemiology, diagnosis, and management of anogenital HPV and HSV infections with an emphasis on treatment modalities for the practicing dermatologist. Diagnosis of these diseases typically relies on clinical assessment, although multiple diagnostic techniques can be utilized and are recommended when diagnosis is uncertain or evaluating an individual with increased risk of malignancy. Management of HPV and HSV infections involves appropriate counseling, screening, and multiple treatment techniques. Particularly for HPV infections, a practitioner may need to use a combination of techniques to achieve the desired outcome.
PMID: 34008162
ISSN: 1179-1888
CID: 4878702

Acrofacial purpura and necrotic ulcerations in COVID-19: a case series from New York City

Karagounis, Theodora K; Shaw, Katharina S; Caplan, Avrom; Lo Sicco, Kristen; Femia, Alisa N
PMID: 32966592
ISSN: 1365-4632
CID: 4615722

Exchanging Dermatoscopes for Stethoscopes: Has the COVID-19 Pandemic Highlighted Gaps in US Dermatology Residency Training?

Shaw, Katharina S; Karagounis, Theodora K; Yin, Lu; Svigos, Katerina; Gibbon, Grace T; Betensky, Rebecca A; Lo Sicco, Kristen I
PMID: 33026742
ISSN: 1545-9616
CID: 4626932