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Comparisons Between Patients at Suburban and Inner-City Facilities Treated With Prostate SBRT: Long-Term Parity in Outcomes Despite Measurable Differences in Demographic and Disease Profiles [Meeting Abstract]

Blacksburg, S. R.; Carpenter, T. J.; Marans, H.; Demircioglu, G.; Witten, M. R.; Repka, M. C.; Mendez, C.; Katz, A. E.; Haas, J. A.
ISI:000582521501385
ISSN: 0360-3016
CID: 4686232

Preliminary results of radiation therapy for prostate cancer in human immunodeficiency virus-positive patients

Ng, Tracy; Stein, Nicholas F; Kaminetsky, Jed; Berman, Steven; Marans, Hillel Y; McDermott, Bill; Berson, Anthony M
OBJECTIVES: The purpose of this study was to report on the clinical outcomes of patients treated at our institution for prostate cancer (PCa) who had been previously diagnosed as Human immunodeficiency virus (HIV) positive. METHODS: The authors conducted a retrospective study of 14 PCa/HIV patients who were being treated for PCa with external beam radiotherapy, brachytherapy, or a combination of the two. Each patient's prostate-specific antigen (PSA) level, CD4 count, and viral load were obtained before the initial radiation treatment and at the time of their most recent follow-up. In addition, 13 of 14 patients completed a quality of life survey with a social worker on staff and were examined by their radiation oncologist to assess the complications after treatment. RESULTS: Comparing pretreatment data with the data at last follow-up, only 1 patient's PSA level remained above 1.1 ng/mL. The average CD4 count remained stable, increasing from 523 to 577 cells/mm(3), with the lowest final count at 200 cells/mm(3). Viral load increased in only 2 of 14 patients. There were no unusual rectal, urinary, or sexual complications, and no infections related to treatment. CONCLUSIONS: Based on changes in viral load and CD4 count, radiotherapy does not appear to have a long-term negative effect on the immune system. Treatment complications are consistent with HIV-negative patients, giving no evidence that the subset of PCa/HIV patients should be treated differently from PCa patients without HIV when considering radiation therapy. More investigation will be necessary before reliable mortality and morbidity data can be assessed
PMID: 18407325
ISSN: 1527-9995
CID: 120718

Fluorine-18-fluorodeoxyglucose dual-head gamma camera coincidence imaging of recurrent colorectal carcinoma [Case Report]

Abdel-Dayem, H M; Radin, A I; Luo, J Q; Marans, H Y; Wong, S; Naddaf, S Y; El-Zeftawy, H M; Omar, W S; Mithilesh, K; Abujudeh, H; Atay, S
We report our experience with coincidence detection imaging of 18F-fluorodeoxyglucose (FDG) using a dual-head gamma camera. Scanning of the pelvis and abdomen of a patient with recurrent colorectal carcinoma showed recurrent disease in the pelvic floor and the base of the urinary bladder and metastatic disease in the retroperitoneal space of the pelvis. Although the tumor involving the bladder and pelvic floor was detected by CT and magnetic resonance imaging (MRI), metastatic spread to the retroperitoneal nodes on the left side was detected only by 18F-FDG imaging. Based on the ultrasound, CT, MRI and cystoscopy, a local recurrence of cancer was presumed in our patient. An exploratory laparotomy was performed to resect the tumor in its entirety. At the time of surgery, the retroperitoneal metastasis in the pelvis was confirmed. Had the findings of the coincidence detection imaging study been considered, the patient would have been spared the surgical procedure.
PMID: 9544675
ISSN: 0161-5505
CID: 200982

Prostatic abscess due to histoplasma capsulatum in the acquired immunodeficiency syndrome [Case Report]

Marans, H Y; Mandell, W; Kislak, J W; Starrett, B; Moussouris, H F
We report a case of prostate abscess due to Histoplasma capsulatum in a patient with the acquired immunodeficiency syndrome. The diagnosis and management are discussed, and the literature is reviewed.
PMID: 2033711
ISSN: 0022-5347
CID: 200972

Granulomatous hepatitis following intravesical bacillus Calmette-Guerin therapy for bladder carcinoma [Case Report]

Marans, H Y; Bekirov, H M
A granulomatous reaction in organs outside of the urinary tract following intravesical bacillus Calmette-Guerin administration is rare. We report a biopsy proved case of granulomatous hepatitis.
PMID: 3795348
ISSN: 0022-5347
CID: 200992