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A call for transparent reporting to optimize the predictive value of preclinical research

Landis, Story C; Amara, Susan G; Asadullah, Khusru; Austin, Chris P; Blumenstein, Robi; Bradley, Eileen W; Crystal, Ronald G; Darnell, Robert B; Ferrante, Robert J; Fillit, Howard; Finkelstein, Robert; Fisher, Marc; Gendelman, Howard E; Golub, Robert M; Goudreau, John L; Gross, Robert A; Gubitz, Amelie K; Hesterlee, Sharon E; Howells, David W; Huguenard, John; Kelner, Katrina; Koroshetz, Walter; Krainc, Dimitri; Lazic, Stanley E; Levine, Michael S; Macleod, Malcolm R; McCall, John M; Moxley, Richard T; Narasimhan, Kalyani; Noble, Linda J; Perrin, Steve; Porter, John D; Steward, Oswald; Unger, Ellis; Utz, Ursula; Silberberg, Shai D
The US National Institute of Neurological Disorders and Stroke convened major stakeholders in June 2012 to discuss how to improve the methodological reporting of animal studies in grant applications and publications. The main workshop recommendation is that at a minimum studies should report on sample-size estimation, whether and how animals were randomized, whether investigators were blind to the treatment, and the handling of data. We recognize that achieving a meaningful improvement in the quality of reporting will require a concerted effort by investigators, reviewers, funding agencies and journal editors. Requiring better reporting of animal studies will raise awareness of the importance of rigorous study design to accelerate scientific progress.
PMID: 23060188
ISSN: 1476-4687
CID: 4502562

Zooming in on seizures [Comment]

Narasimhan, Kalyani
PMID: 22281714
ISSN: 1546-1726
CID: 4502552

Studying cortical depression in vivo [Comment]

Narasimhan, Kalyani
PMID: 17525759
ISSN: 1097-6256
CID: 4502542

Unraveling the mechanisms of Angelman Syndrome

Narasimhan, Kalyani
PMID: 17318219
ISSN: 1097-6256
CID: 4502532

New clues for axonal repair in ALS [Comment]

Narasimhan, Kalyani
PMID: 17066065
ISSN: 1097-6256
CID: 4502522

Quantifying motor neuron loss in ALS

Narasimhan, Kalyani
PMID: 16498424
ISSN: 1097-6256
CID: 4502512

Brain's guard cells show their agility [Comment]

Narasimhan, Kalyani
PMID: 15917834
ISSN: 1097-6256
CID: 4502502

SK channels: a new twist to synaptic plasticity [Comment]

Narasimhan, Kalyani
PMID: 15856059
ISSN: 1097-6256
CID: 4502492

Assaying axon sensitivity [Comment]

Narasimhan, Kalyani
PMID: 15162165
ISSN: 1097-6256
CID: 4502482

Pulling the Soxs off proliferation [Comment]

Narasimhan, Kalyani
PMID: 14583752
ISSN: 1097-6256
CID: 4502472