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The vial can help: Standardizing vial design to reduce the risk of medication errors

Bitan, Yuval; O'Connor, Michael F; Nunnally, Mark E
PMID: 38251720
ISSN: 1537-1913
CID: 5624642

A Review and Discussion of Full-Time Equivalency and Appropriate Compensation Models for an Adult Intensivist in the United States Across Various Base Specialties

Nurok, Michael; Flynn, Brigid C; Pineton de Chambrun, Marc; Kazemian, Mina; Geiderman, Joel; Nunnally, Mark E
OBJECTIVES/OBJECTIVE:Physicians with training in anesthesiology, emergency medicine, internal medicine, neurology, and surgery may gain board certification in critical care medicine upon completion of fellowship training. These clinicians often only spend a portion of their work effort in the ICU. Other work efforts that benefit an ICU infrastructure, but do not provide billing opportunities, include education, research, and administrative duties. For employed or contracted physicians, there is no singular definition of what constitutes an intensive care full-time equivalent (FTE). Nevertheless, hospitals often consider FTEs in assessing hiring needs, salary, and eligibility for benefits. DATA SOURCES/METHODS:Review of existing literature, expert opinion. STUDY SELECTION/METHODS:Not applicable. DATA EXTRACTION/METHODS:Not applicable. DATA SYNTHESIS/RESULTS:Not applicable. CONCLUSIONS:Understanding how an FTE is calculated, and the fraction of an FTE to be assigned to a particular cost center, is therefore important for intensivists of different specialties, as many employment models assign salary and benefits to a base specialty department and not necessarily the ICU.
PMCID:10965199
PMID: 38533294
ISSN: 2639-8028
CID: 5644842

Surviving Sepsis Campaign Research Priorities 2023

De Backer, Daniel; Deutschman, Clifford S; Hellman, Judith; Myatra, Sheila Nainan; Ostermann, Marlies; Prescott, Hallie C; Talmor, Daniel; Antonelli, Massimo; Pontes Azevedo, Luciano Cesar; Bauer, Seth R; Kissoon, Niranjan; Loeches, Ignacio-Martin; Nunnally, Mark; Tissieres, Pierre; Vieillard-Baron, Antoine; Coopersmith, Craig M; ,
OBJECTIVES/OBJECTIVE:To identify research priorities in the management, epidemiology, outcome, and pathophysiology of sepsis and septic shock. DESIGN/METHODS:Shortly after publication of the most recent Surviving Sepsis Campaign Guidelines, the Surviving Sepsis Research Committee, a multiprofessional group of 16 international experts representing the European Society of Intensive Care Medicine and the Society of Critical Care Medicine, convened virtually and iteratively developed the article and recommendations, which represents an update from the 2018 Surviving Sepsis Campaign Research Priorities. METHODS:Each task force member submitted five research questions on any sepsis-related subject. Committee members then independently ranked their top three priorities from the list generated. The highest rated clinical and basic science questions were developed into the current article. RESULTS:A total of 81 questions were submitted. After merging similar questions, there were 34 clinical and ten basic science research questions submitted for voting. The five top clinical priorities were as follows: 1) what is the best strategy for screening and identification of patients with sepsis, and can predictive modeling assist in real-time recognition of sepsis? 2) what causes organ injury and dysfunction in sepsis, how should it be defined, and how can it be detected? 3) how should fluid resuscitation be individualized initially and beyond? 4) what is the best vasopressor approach for treating the different phases of septic shock? and 5) can a personalized/precision medicine approach identify optimal therapies to improve patient outcomes? The five top basic science priorities were as follows: 1) How can we improve animal models so that they more closely resemble sepsis in humans? 2) What outcome variables maximize correlations between human sepsis and animal models and are therefore most appropriate to use in both? 3) How does sepsis affect the brain, and how do sepsis-induced brain alterations contribute to organ dysfunction? How does sepsis affect interactions between neural, endocrine, and immune systems? 4) How does the microbiome affect sepsis pathobiology? 5) How do genetics and epigenetics influence the development of sepsis, the course of sepsis and the response to treatments for sepsis? CONCLUSIONS:Knowledge advances in multiple clinical domains have been incorporated in progressive iterations of the Surviving Sepsis Campaign guidelines, allowing for evidence-based recommendations for short- and long-term management of sepsis. However, the strength of existing evidence is modest with significant knowledge gaps and mortality from sepsis remains high. The priorities identified represent a roadmap for research in sepsis and septic shock.
PMID: 38240508
ISSN: 1530-0293
CID: 5624442

Is Expertise Evidence? Insights From A New Guideline

Nunnally, Mark E
PMID: 37971342
ISSN: 1530-0293
CID: 5610572

Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention from the European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery

Hinkelbein, Jochen; Andres, Janusz; Böttiger, Bernd W; Brazzi, Luca; De Robertis, Edoardo; Einav, Sharon; Gwinnutt, Carl; Kuvaki, Bahar; Krawczyk, Pawel; McEvoy, Matthew D; Mertens, Pieter; Moitra, Vivek K; Navarro-Martinez, Jose; Nunnally, Mark E; O'Connor, Michael; Rall, Marcus; Ruetzler, Kurt; Schmitz, Jan; Thies, Karl; Tilsed, Jonathan; Zago, Mauro; Afshari, Arash
INTRODUCTION/BACKGROUND:Cardiac arrest in the operating room is a rare but potentially life-threatening event with mortality rates of more than 50%. Contributing factors are often known, and the event is recognised rapidly as patients are usually under full monitoring. This guideline covers the perioperative period and is complementary to the European Resuscitation Council (ERC) guidelines. MATERIAL AND METHODS/METHODS:The European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery jointly nominated a panel of experts to develop guidelines for the recognition, treatment and prevention of cardiac arrest in the perioperative period. A literature search was conducted in MEDLINE, EMBASE, CINAHL and the Cochrane Central Register of Controlled Trials. All searches were restricted to publications from 1980 to 2019 inclusive and to the English, French, Italian and Spanish languages. The authors also contributed individual, independent literature searches. RESULTS:This guideline contains background information and recommendation for the treatment of cardiac arrest in the operating room environment, and addresses controversial topics such as open chest cardiac massage (OCCM), resuscitative endovascular balloon occlusion (REBOA) and resuscitative thoracotomy, pericardiocentesis, needle decompression and thoracostomy. CONCLUSION/CONCLUSIONS:Successful prevention and management of cardiac arrest during anaesthesia and surgery requires anticipation, early recognition and a clear treatment plan. The ready availability of expert staff and equipment must also be taken into consideration. Success not only depends on medical knowledge, technical skills and a well organised team using crew resource management but also on an institutional safety culture embedded in everyday practice through continuous education, training and multidisciplinary co-operation.
PMID: 37218626
ISSN: 1365-2346
CID: 5543692

Revising the Process and Structure of the Society of Critical Care Medicine Guidelines Toward a Living Guideline Model

Nunnally, Mark E; Dager, William E; Patel, Hariyali; Al-Hazzani, Waleed; Nadkarni, Vinay M; Kane-Gill, Sandra L
PMID: 37707376
ISSN: 1530-0293
CID: 5593812

Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention from the European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery

Hinkelbein, Jochen; Andres, Janusz; Böttiger, Bernd W; Brazzi, Luca; De Robertis, Edoardo; Einav, Sharon; Gwinnutt, Carl; Kuvaki, Bahar; Krawczyk, Pawel; McEvoy, Matthew D; Mertens, Pieter; Moitra, Vivek K; Navarro-Martinez, Jose; Nunnally, Mark E; O Connor, Michael; Rall, Marcus; Ruetzler, Kurt; Schmitz, Jan; Thies, Karl; Tilsed, Jonathan; Zago, Mauro; Afshari, Arash
INTRODUCTION/BACKGROUND:Cardiac arrest in the operating room is a rare but potentially life-threatening event with mortality rates of more than 50%. Contributing factors are often known, and the event is recognised rapidly as patients are usually under full monitoring. This guideline covers the perioperative period and is complementary to the European Resuscitation Council guidelines. MATERIAL AND METHODS/METHODS:The European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery jointly nominated a panel of experts to develop guidelines for the recognition, treatment, and prevention of cardiac arrest in the perioperative period. A literature search was conducted in MEDLINE, EMBASE, CINAHL and the Cochrane Central Register of Controlled Trials. All searches were restricted to publications from 1980 to 2019 inclusive and to the English, French, Italian and Spanish languages. The authors also contributed individual, independent literature searches. RESULTS:This guideline contains background information and recommendation for the treatment of cardiac arrest in the operating room environment, and addresses controversial topics such as open chest cardiac massage, resuscitative endovascular balloon occlusion and resuscitative thoracotomy, pericardiocentesis, needle decompression, and thoracostomy. CONCLUSIONS:Successful prevention and management of cardiac arrest during anaesthesia and surgery requires anticipation, early recognition, and a clear treatment plan. The ready availability of expert staff and equipment must also be taken into consideration. Success not only depends on medical knowledge, technical skills and a well-organised team using crew resource management, but also on an institutional safety culture embedded in everyday practice through continuous education, training, and multidisciplinary co-operation.
PMID: 37430174
ISSN: 1863-9941
CID: 5537502

Guidelines and principles for the care of the cardiothoracic transplant patient in the intensive care unit

Nurok, Michael; Nunnally, Mark E; O'Connor, Michael; Pierson, Richard N; Baran, David A; Harper, Michael D; Malinoski, Darren; El Banayosy, Aly; Orija, Abiodun; Hall, Shelley; Edelman, Jeffrey D; Sundt, Thoralf M; Levine, Deborah; Kobashigawa, Jon; Nelson, David
Heart and lung transplant recipients require care provided by clinicians from multiple different specialties, each contributing unique expertise and perspective. The period the patient spends in the intensive care unit is one of the most critical times in the perioperative trajectory. Various organizational models of intensive care exist, including those led by intensivists, surgeons, transplant cardiologists, and pulmonologists. Coordinating timely efficient intensive care is an essential and logistically difficult goal. The present work product of the American Society of Transplantation's Thoracic and Critical Care Community of Practice, Critical Care Task Force outlines operational guidelines and principles that may be applied in different organizational models to optimize the delivery of intensive care for the cardiothoracic organ recipient.
PMID: 36964943
ISSN: 1399-0012
CID: 5462962

Nationwide Clinical Practice Patterns of Anesthesiology Critical Care Physicians-A Survey to Members of the Society of Critical Care Anesthesiologists

Shaefi, Shahzad; Pannu, Ameeka; Mueller, Ariel L; Flynn, Brigid; Evans, Adam; Jabaley, Craig S; Mladinov, Domagoj; Wall, Michael; Siddiqui, Shahla; Douin, David J; Boone, M Dustin; Monteith, Erika; Abalama, Vivian; Nunnally, Mark E; Cobas, Miguel; Warner, Matthew A; Stevens, Robert D
BACKGROUND:Despite the growing contributions of critical care anesthesiologists to clinical practice, research, and administrative leadership of intensive care units (ICUs), relatively little is known about the subspecialty-specific clinical practice environment. An understanding of contemporary clinical practice is essential to recognize the opportunities and challenges facing critical care anesthesia, optimize staffing patterns, assess sustainability and satisfaction, and strategically plan for future activity, scope, and training. This study surveyed intensivists who are members of the Society of Critical Care Anesthesiologists (SOCCA) to evaluate practice patterns of critical care anesthesiologists, including compensation, types of ICUs covered, models of overnight ICU coverage, and relationships between these factors. We hypothesized that variability in compensation and practice patterns would be observed between individuals. METHODS:Board-certified critical care anesthesiologists practicing in the United States were identified using the SOCCA membership distribution list and invited to take a voluntary online survey between May and June 2021. Multiple-choice questions with both single- and multiple-select options were used for answers with categorical data, and adaptive questioning was used to clarify stem-based responses. Respondents were asked to describe practice patterns at their respective institutions and provide information about their demographics, salaries, effort in ICUs, as well as other activities. RESULTS:A total of 490 participants were invited to take this survey, and 157 (response rate 32%) surveys were completed and analyzed. The majority of respondents were White (73%), male (69%), and younger than 50 years of age (82%). The cardiothoracic/cardiovascular ICU was the most common practice setting, with 69.5% of respondents reporting time working in this unit. Significant variability was observed in ICU practice patterns. Respondents reported spending an equal proportion of their time in clinical practice in the operating rooms and ICUs (median, 40%; interquartile range [IQR], 20%-50%), whereas a smaller proportion-primarily those who completed their training before 2009-reported administrative or research activities. Female respondents reported salaries that were $36,739 less than male respondents; however, this difference was not statistically different, and after adjusting for age and practice type, these differences were less pronounced (-$27,479.79; 95% confidence interval [CI], -$57,232.61 to $2273.03; P = .07). CONCLUSIONS:These survey data provide a current snapshot of anesthesiology critical care clinical practice patterns in the United States. Our findings may inform decision-making around the initiation and expansion of critical care services and optimal staffing patterns, as well as provide a basis for further work that focuses on intensivist satisfaction and burnout.
PMID: 35950751
ISSN: 1526-7598
CID: 5287072

A survey of intensive care unit models in cardiothoracic transplantation at high-volume centers [Letter]

Nurok, Michael; Nunnally, Mark E; Gill, George; O'Connor, Michael; Harper, Michael; Edelman, Jeffrey; Orija, Abiodun; Banayosy, Aly El; Malinoski, Darren; Sundt, Thor; Baran, David A; Levine, Deborah; Hall, Shelley; Kobashigawa, Jon; Nelson, David
PMID: 36630254
ISSN: 1399-0012
CID: 5419052