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QuilliChew extended-release chewable tablets for the treatment of ADHD in patients ages 6 years old and above

Childress, Ann; Ponce De Leon, Bernice; Owens, Mark
INTRODUCTION/BACKGROUND:(MPH-ERCT) is an ER methylphenidate designed to be chewed before swallowing. The technology and pharmacokinetics, along with efficacy and safety data, are presented. Expert opinion: Extensive safety and efficacy data exist for MPH. ER formulations can be distinguished by preparation (tablet, capsule, liquid) and onset and duration of effect, but efficacy is similar for all ER MPH products. Each formulation has attributes, such as ease of titration, portability, and taste, that make it more acceptable for certain patients. Because AMPH and MPH are so effective, current technology research is focused on improving safety, convenience, and onset and duration of effect.
PMID: 30404549
ISSN: 1744-7593
CID: 3543002

Maternal suicide: rates and trends

McGowan, Iain; Sinclair, Marlene; Owens, Mark
PMID: 17476836
ISSN: 1479-2915
CID: 103798

Efficacy and tolerability of divalproex extended release in psychiatric patients [Letter]

Jackson, Richard S; Venkataraman, Sanjeev; Atkins, Richard B; Owens, Mark
PMID: 17162629
ISSN: 1040-1237
CID: 103799

Military issues

Ritchie, Elspeth Cameron; Owens, Mark
This article reviews of some of the lessons in trauma psychiatry learned by the US military through wartime and other trauma experiences during the past century. Current practice in the military's employment of stress control teams is reviewed. The military's efforts to prevent and limit psychological casualties, to include the care of battle casualties and prisoners of war (POWs), are addressed.Recent experiences that have informed further, and are shaping the military's approach to managing the psychological aftermath of trauma (such as the Sept. 11, 2001, attack on the Pentagon and the current war with Iraq) are included. Guidelines developed after 9/11, and articulated in the 'Mass Violence and Early Intervention' conference are presented. Finally, current ideas on preparation for and intervention after weapons of mass destruction will be outlined
PMID: 15325487
ISSN: 0193-953X
CID: 103800

Allergic rhinitis in children with attention-deficit/hyperactivity disorder

Brawley, Ashley; Silverman, Bernard; Kearney, Shannon; Guanzon, Denise; Owens, Mark; Bennett, Harvey; Schneider, Arlene
BACKGROUND: Both allergic rhinitis and attention-deficit/hyperactivity disorder (ADHD) are common pediatric conditions associated with learning difficulties and sleep disturbances. There are conflicting research data regarding the association between ADHD and atopic disorders. OBJECTIVE: To determine the prevalence of allergic rhinitis in patients with physician-diagnosed ADHD. METHODS: Patients 5 to 18 years of age who presented with a Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition diagnosis of ADHD to an outpatient pediatric psychiatry clinic were screened for allergic rhinitis with focused history, physical examination, and skin prick testing to common aeroallergens. RESULTS: Thirty patients were interviewed, with 23 of these undergoing physical examination and skin prick testing. Eighty percent reported allergic rhinitis symptoms, whereas 61% had at least 1 positive prick skin test result. Forty-three percent showed typical physical signs of allergic rhinitis, 100% had a positive atopic family history, and 53% had other associated atopic disorders. CONCLUSIONS: Most children with ADHD displayed symptoms and skin prick test results consistent with allergic rhinitis. Nasal obstruction and other symptoms of allergic rhinitis could explain some of the cognitive patterns observed in ADHD, which might result from sleep disturbance known to occur with allergic rhinitis. Therefore, evaluation and treatment of allergic rhinitis could benefit patients with ADHD
PMID: 15237769
ISSN: 1081-1206
CID: 103801