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Gynecologic injuries: Trauma to uterus, ovaries, and female genitalia

Chapter by: Petrone, Patrizio; Marini, Corrado P.; Tillou, Areti
in: Current Therapy of Trauma and Surgical Critical Care by
[S.l.] : Elsevier, 2023
pp. 431-438.e1
ISBN: 9780323697873
CID: 5615692

The First COVID-19 Pandemic Wave and the Effect on Health Care Trainees: A National Survey Study

Liu, Helen H; Petrone, Patrizio; Akerman, Meredith; Howell, Raelina S; Morel, Andrew H; Sohail, Amir H; Alsamarraie, Cindy; Brathwaite, Barbara; Kinzler, Wendy; Maurer, James; Brathwaite, Collin E M
BACKGROUND:This study observes the trends and patterns among trainees during the coronavirus disease 2019 (COVID-19) pandemic and their response to resident education and hospital/program support. METHODS:An anonymous online 31-question survey was distributed to medical students and postgraduate year residents. Topics included were demographics, clinical responsibilities, educational/curricula changes, and trainee wellness. Descriptive analysis was performed for each set of demographic groupings as well as 2 and 3 group comparisons. RESULTS:< .0001). CONCLUSION/CONCLUSIONS:We aim to provide continued educational support for our trainees' clinical development and well-being during the COVID-19 pandemic.
PMCID:9483660
PMID: 36121024
ISSN: 1555-9823
CID: 5333002

Coronavirus Disease 2019 and the Injured Patient: A Multicenter Review

Hakmi, Hazim; Islam, Shahidul; Petrone, Patrizio; Sajan, Abin; Baltazar, Gerard; Sohail, Amir H; Goulet, Nicole; Jacquez, Ricardo; Stright, Adam; Velcu, Laura; Divers, Jasmin; Joseph, D'Andrea K
INTRODUCTION/BACKGROUND:Coronavirus disease 2019 (COVID-19) has been shown to affect outcomes among surgical patients. We hypothesized that COVID-19 would be linked to higher mortality and longer length of stay of trauma patients regardless of the injury severity score (ISS). METHODS:We performed a retrospective analysis of trauma registries from two level 1 trauma centers (suburban and urban) from March 1, 2019, to June 30, 2019, and March 1, 2020, to June 30, 2020, comparing baseline characteristics and cumulative adverse events. Data collected included ISS, demographics, and comorbidities. The primary outcome was time from hospitalization to in-hospital death. Outcomes during the height of the first New York COVID-19 wave were also compared with the same time frame in the prior year. Kaplan-Meier method with log-rank test and Cox proportional hazard models were used to compare outcomes. RESULTS:There were 1180 trauma patients admitted during the study period from March 2020 to June 2020. Of these, 596 were never tested for COVID-19 and were excluded from the analysis. A total of 148 COVID+ patients and 436 COVID- patients composed the 2020 cohort for analysis. Compared with the 2019 cohort, the 2020 cohort was older with more associated comorbidities, more adverse events, but lower ISS. Higher rates of historical hypertension, diabetes, neurologic events, and coagulopathy were found among COVID+ patients compared with COVID- patients. D-dimer and ferritin were unreliable indicators of COVID-19 severity; however, C-reactive protein levels were higher in COVID+ relative to COVID- patients. Patients who were COVID+ had a lower median ISS compared with COVID- patients, and COVID+ patients had higher rates of mortality and longer length of stay. CONCLUSIONS:COVID+ trauma patients admitted to our two level 1 trauma centers had increased morbidity and mortality compared with admitted COVID- trauma patients despite age and lower ISS. C-reactive protein may play a role in monitoring COVID-19 activity in trauma patients. A better understanding of the physiological impact of COVID-19 on injured patients warrants further investigation.
PMCID:9263818
PMID: 36084394
ISSN: 1095-8673
CID: 5337332

The incidence and the impact of deep vein thrombosis on the outcome of patients with COVID-19 infection

Marini, Corrado P; Lewis, Erin; Petrone, Patrizio; Zenilman, Ariela; Lu, Zhai; Rivera, Aksim; McNelis, John
BACKGROUND:Deep vein thrombosis (DVT) has been reported to occur at varying rates in patients with COVID-19. Limited data exist regarding comparison with non-Covid-19 patients with similar characteristics. The objective was to compare the rates of DVT in patients with and without COVID-19 and to determine the impact of DVT on outcome. METHODS:Retrospective, observational cohort study. Single institution, level 1 Trauma Center. COVID-19 patients compared with a group of non-COVID-19. Patients included a non-COVID-19 group from March 20, 2019 to June 30, 2019 and a COVID-19 group from the same interval in 2020. Standard prophylactic anticoagulation with heparin 5,000 units three times daily or enoxaparin 40 mg daily not weight adjusted (n=573) and enoxaparin 40 mg daily not weight adjusted (n=213). Two primary outcomes included the rate of DVT in the COVID-19 group compared to the historic control, and the impact of DVT on mortality. Subgroup analysis included patients with adult respiratory distress syndrome (ARDS), pulmonary embolism (PE), and intensive care unit patients (ICU). RESULTS:The rate of DVT and PE in the 573 patients, age 61 ± 17 years, male 44.9%, was 71/573 (12.4%) and 19/573 (3.3%) compared to 72/213 (33.8%) and 15.213 (7.0%) in COVID-19 patients, age 61 ± 16 years, male 61.0%. Unprovoked PE occurred in 10/15 (66.7%) in COVID-19 patients compared to 8/497 (1.6%) in non-COVID-19. Patients with ARDS (n=60) had an incidence of DVT 28/60 (46.7%) versus 44/153 (28.8%), p=0.01. ICU patients had an increased rate of DVT in COVID-19 patients: 39/90 (43.3%) versus 33/123 (33.3%), p=0.01. Risk factors for mortality included age, DVT, multiple organ failure syndrome, and prolonged ventilatory support with the following odd ratios: 1.030, 95% CI 1.002 - 1.058, 2.847, 95% CI 1.356-5.5979, 4.438, 95% CI 1.973-9.985, and 5.321, 95% CI 1.973-14.082. CONCLUSIONS:The incidence of DVT in COVID-19 patients receiving standard dose not weight-adjusted prophylactic anticoagulation is high, particularly in ICU patients. DVT is one of the contributing factors to increased mortality. These results suggest re-evaluation of the present standard dose thromboprophylaxis in patients with COVID-19.
PMCID:8582229
PMID: 34775121
ISSN: 2213-3348
CID: 5048872

Flags and their influence on social behavior Las banderas y su influencia en la conducta social

Petrone, Patrizio
SCOPUS:85132550510
ISSN: 2011-7582
CID: 5315242

Stop the Bleed: A Prospective Evaluation and Comparison of Tourniquet Application in Security Personnel Versus Civilian Population

Petrone, Patrizio; Baltazar, Gerard; Jacquez, Ricardo A; Akerman, Meredith; Brathwaite, Collin E M; Joseph, D'Andrea K
INTRODUCTION/BACKGROUND:Stop the Bleed (STB) is a national training program aiming to decrease the mortality associated with life-threatening bleeding due to injury. The purpose of this study was to evaluate the efficacy and confidence level of security personnel placing a tourniquet (TQ) compared to civilians. METHODS:Pre and post questionnaires were shared with security personnel (Group 1) and civilians (Group 2). Both groups were assessed to determine comfort level with TQ placement. Time and success rate for placement was recorded pre- and post-STB training. A generalized linear mixed model or generalized estimating equations was used to compare pre and post measurements. RESULTS:There were 234 subjects enrolled. There was a statistically significant improvement between the pre- and post-training responses in both groups with respect to comfort level in placing a TQ. Participants also demonstrated increased familiarity with the anatomy and bleeding control after STB training. A higher successful TQ placement was obtained in both groups after STB training (Pre-training: Group 1 [17.4%], Group 2 [12.8%]; Post-training: Group 1 [94.8%], Group 2 [92.3%]). Both groups demonstrated improved time to TA placement with a longer mean time improvement achieved in Group 1. Although the time to TQ placement pre-and post-training was statistically significant, we found that the post-training times between Groups 1 and 2 were similar (P = .983). CONCLUSIONS:Participants improved their confidence level with the use of hemorrhage control techniques and dramatically increased the rate and time to successful placement of a TQ. While civilians had the greatest increase in comfort level, the security personnel group saw the most significant reduction in the time to successful TQ placement. These findings highlight the critical role of STB in educating and empowering both civilians and security personnel in bleeding control techniques.
PMID: 35567282
ISSN: 1555-9823
CID: 5215142

Multimodality Monitoring and Goal-Directed Therapy for the Treatment of Patients with Severe Traumatic Brain Injury: A Review for the General and Trauma Surgeon

Marini, Corrado P; McNelis, John; Petrone, Patrizio
PMID: 35428444
ISSN: 1535-6337
CID: 5204522

Outcomes in Obese vs Non-Obese Injured Patients at a Level 1 Trauma Center and Bariatric Surgery Center of Excellence

Petrone, Patrizio; Joseph, D'Andrea K; Baltazar, Gerard; Akerman, Meredith; Howell, Raelina S; Brathwaite, Collin E M
BACKGROUND:We hypothesized that the outcomes of trauma patients with a body mass index (BMI) equal to or greater than 30 compared to patients with BMI less than 30 would not differ at a level 1 trauma center that is also a Metabolic and Bariatric Surgery Center of Excellence in the Metabolic and Bariatric Surgery Accreditation Quality Improvement Program (MBSAQIP). STUDY DESIGN/METHODS:Patients equal to and greater than 18 years old treated between 1/1/2018 and 12/31/2020 were included. Demographics, BMI, comorbidities, and outcomes (hospital-LOS, ICU-LOS, blood products used, and mortality) were compared between 2 groups: obese (BMI ≥30) vs non-obese (BMI <30). RESULTS:< .0001). When adjusted for age, sex, DM, dementia, ISS, and ICU admission, there was no statistically significant difference in hospital-LOS (4.30 [95% CI: 4.10, 4.52] vs 4.48 [95% CI: 4.18, 4.79]) or mortality. No statistical differences were seen between the 2 groups in blood product use. CONCLUSIONS:Obesity did not correlate with poorer outcomes at an ACS-verified level 1 Trauma Center and Bariatric Surgery Center of Excellence. Further studies are needed to determine whether outcomes vary at hospitals without both designations.
PMID: 35343242
ISSN: 1555-9823
CID: 5200882

Missed traumatic abdominal injury with challenging management: report of 12-year follow-up [Case Report]

Ceballos-Esparragón, José J; Servide-Staffolani, María José; Petrone, Patrizio
Despite well-established clinical guidelines and use of radiologic imaging for diagnosis, challenges are faced when accurate decisions must be made within seconds. Patients with life-threatening injuries represent 10-15% of all hospitalized trauma patients. In fact, 20% of abdominal injuries will require surgical intervention. In abdominal trauma, it is important to distinguish the difference between surgical intervention, which includes damage control procedures and definitive treatment. The main objective of damage control surgery is to control the bleeding, reduce the contamination and delay additional surgical stress at a time of physiological vulnerability of the patient, along with abdominal containment, visceral protection and avoiding aponeurotic retraction in situations where primary abdominal closure is not possible. However, this technique has high morbidity and comes with a myriad of complications, including development of catastrophic abdomen and formation of enterocutaneous fistulas.
PMCID:8937614
PMID: 35350218
ISSN: 2042-8812
CID: 5219902

Smartphone application alerts for early trauma team activation: Millennial technology in healthcare

Goulet, Nicole D; Liu, Helen; Petrone, Patrizio; Islam, Shahidul; Glinik, Galina; Joseph, D'Andrea K; Baltazar, Gerard A
BACKGROUND:Data access through smartphone applications (apps) has reframed procedure and policy in healthcare, but its impact in trauma remains unclear. Citizen is a free app that provides real-time alerts curated from 911 dispatch data. Our primary objective was to determine whether app alerts occurred earlier than recorded times for trauma team activation and emergency department arrival. METHODS:Trauma registry entries were extracted from a level one urban trauma center from January 1, 2018 to June 30, 2019 and compared with app metadata from the center catchment area. We matched entries to metadata according to description, date, time, and location then compared metadata timestamps to trauma team activation and emergency department arrival times. We computed percentage of time the app reported traumatic events earlier than trauma team activation or emergency department arrival along with exact binomial 95% confidence interval; median differences between times were presented along with interquartile ranges. RESULTS:Of 3,684 trauma registry entries, 209 (5.7%) matched app metadata. App alerts were earlier for 96.1% and 96.2% of trauma team activation and emergency department arrival times, respectively, with events reported median 36 (24-53, IQR) minutes earlier than trauma team activation and 32 (25-42, IQR) minutes earlier than emergency department arrival. Registry entries for younger males, motor vehicle-related injuries and penetrating traumas were more likely to match alerts (P < .0001). CONCLUSION/CONCLUSIONS:Apps like Citizen may provide earlier notification of traumatic events and therefore earlier mobilization of trauma service resources. Earlier notification may translate into improved patient outcomes. Additional studies into the benefit of apps for trauma care are warranted.
PMID: 34210527
ISSN: 1532-7361
CID: 4927182