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Is maternal weight gain correlated to successful vaginal birth after cesarean (VBAC) rate? [Meeting Abstract]

Roshan, Daniel; Migotsky, John; Roshan, Ariel; Abrahams, Michael; Mobasseri, Marjon; Jaffe, Ira
ISSN: 0002-9378
CID: 4482172

Does Chorionic Villus Sampling Increase the Incidence of Echogenic Bowel on Second Trimester Ultrasound [Meeting Abstract]

Petrikovsky, B; Monga, S; Klapper, A; Jaffe, I; Roshan, D
ISSN: 1933-7191
CID: 110126

Successful pregnancy outcome in Ehlers-Danlos syndrome, vascular type

Palmquist, Maria; Pappas, John G; Petrikovsky, Boris; Blakemore, Karin; Roshan, Daniel
BACKGROUND: Ehlers-Danlos syndrome (EDS) is a rare connective tissue disorder characterized by tissue fragility, translucent skin and joint hypermobility. Patients with the vascular type of EDS are prone to spontaneous arterial and visceral rupture. Pregnancy for women with vascular EDS can be life-threatening. Mortality rates are high due to the increased risk for uterine and arterial rupture in the peripartum period. CASE: We describe the counseling, multidisciplinary management, protocol, and successful pregnancy outcome of a 32-year-old woman with vascular EDS. CONCLUSION: There is no consensus in the literature on the timing and mode of delivery for pregnant women with vascular EDS. The management undertaken in our patient may assist others in optimizing the perinatal outcome in other women who elect to continue their pregnancy despite the risks of this severe medical condition
PMID: 19591069
ISSN: 1476-4954
CID: 145548

Antenatal treatment of fetal goiter: a therapeutic challenge [Case Report]

Hanono, Anat; Shah, Bina; David, Raphael; Buterman, Irving; Roshan, Daniel; Shah, Shetal; Lam, Leslie; Timor-Tritsch, Ilan
OBJECTIVE: Pre-natal ultrasonography presents an opportunity for in-utero therapy of a fetal goiter. Because of the morbidity associated with a large goiter and the risks of repeated intra-amniotic injections, controversy arose about the precise indications of this mode of treatment. We describe our observations in treating a 22-week-old fetus with a large goiter because of dyshormogenesis, monitored with serial 3D high frequency, high resolution ultrasonography and amniotic hormonal measurements. Fetal hypothyroidism was confirmed by cordocentesis and amniotic hormone levels. After assessment of relevant risk factors and the criteria for in-utero intervention, including goiter volume, amniotic fluid index, polyhydramnios and tracheal compression, we determined that hormonal therapy was warranted. Levothyroxine was injected every 7-10 days, and its efficacy monitored by ultrasound changes and amniotic hormone sampling. RESULTS: Reduction in goiter volume restored normal neck flexion relieving the pressure on the trachea, polyhydramnios was prevented and amniotic hormone levels were normalised. The infant was euthyroid at birth, however, by age 4 days hypothyroidism was diagnosed, and treatment with l-thyroxine started. CONCLUSION: Advances in fetal ultrasonography permit judicious therapy of an enlarging goiter in a hypothyroid fetus, which may contribute to enhancing cognitive development. We discuss the value of amniotic hormone sampling, the objectives and risks of in-utero intervention in the light of recent literature and our own observations
PMID: 19085636
ISSN: 1476-4954
CID: 96296

Bradycardias following cordocenteses: are they always ominous?

Most OL; Petrikovsky BM; Roshan D
ISSN: 1062-2454
CID: 73079

Pregnancy outcomes after failed abortion [Meeting Abstract]

Roshan, D; Petrikovsky, B
ISSN: 0029-7844
CID: 70617

Predictive values of modified biophysical profile [Meeting Abstract]

Roshan, D; Petrikovsky, B
ISSN: 0029-7844
CID: 70618

Predictive values of modified biophysical profile [Meeting Abstract]

Roshan, D; Petrikovsky, B
ISSN: 1071-5576
CID: 62830

Is cervical index a useful predictory value for successful induction of labor in nulliparous patients? [Meeting Abstract]

Petrikovsky, B; Roshan, D
ISSN: 0002-9378
CID: 73614

The accuracy and usefulness of three-dimensional color power fetal echocardiography [Meeting Abstract]

Roshan, D; Petrikovsky, B; Challenger, M
ISSN: 0029-7844
CID: 52639