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Biatrial drainage of right superior vena cava with left superior vena cava: A diagnostic conundrum [Case Report]

Bhansali, Suneet; Cohen, Roi B; Halpern, Dan; Saharan, Sunil; Saric, Muhamed; Kumar, T K Susheel; Mosca, Ralph S
PMID: 35967232
ISSN: 2666-2507
CID: 5299732

Non-surgical treatment of congenital left ventricle to coronary sinus fistula and Wolf-Parkinson-White

Minocha, Prashant K; Saharan, Sunil; Chun, Anne; Presti, Salvatore; Cecchin, Frank; Argilla, Michael
Congenital left ventricle to coronary sinus fistula is a rare entity. We report a case of an infant with prenatal finding of left ventricle to right atrial shunt. The anatomy was defined by multi-modality imaging. Baseline electrocardiogram was notable for a Wolff-Parkinson-White pattern. He underwent successful catheter device closure of the left ventricle to coronary sinus fistula. The patient developed supraventricular tachycardia and underwent successful ablation of the accessory pathway.
PMID: 35383549
ISSN: 1467-1107
CID: 5201622

Preservation of Antegrade Pulmonary Blood Flow in Kawashima Procedure With Prior Right Ventricular Outflow Tract Stent

Bhansali, Suneet; Bhatla, Puneet; Argilla, Michael; Saharan, Sunil; Mosca, Ralph; Kumar, Tk Susheel
Surgical management of single ventricle with interrupted inferior vena cava and azygos continuation typically requires a Kawashima procedure with subsequent completion of Fontan. However, this group is at risk of development of pulmonary arteriovenous malformations. Evidence suggests preservation of hepatic venous flow into the pulmonary circulation can potentially delay this development. We hereby describe a method of preserving antegrade pulmonary blood flow during the Kawashima procedure in the setting of prior right ventricular outflow tract stents.
PMID: 35171728
ISSN: 2150-136x
CID: 5163502

Patent foramen ovale in children: Unique pediatric challenges and lessons learned from adult literature

Saharan, Sunil; Vettukattil, Joseph; Bhat, Aarti; Amula, Venu; Bansal, Manish; Chowdhury, Devyani; Dyamenahalli, Umesh; Gupta, Saurabh Kumar; Das, Bibhuti; Susheel Kumar, T K; Muralidaran, Ashok; Trivedi, Kalyani; Swaminathan, Sethuraman; Bansal, Neha; Doshi, Unnati; Hoskoppal, Arvind; Balaji, Seshadri
A patent foramen ovale (PFO) is a frequent incidental finding during echocardiography in otherwise healthy children. In most healthy children with a diagnosis of isolated incidental PFO, no further follow-up or intervention is necessary. In some children, PFO is associated with certain clinical syndromes such as cryptogenic stroke, decompression sickness, migraine, and platypnea-orthodeoxia syndrome. This review discusses PFO anatomy, diagnostic imaging, PFO-associated clinical situations, management options, and the role of PFO in certain congenital heart disease. This review also highlights the current deficiency of pediatric data guiding management of these uncommon but important PFO-associated conditions. Future multicenter randomized controlled studies are necessary to guide the management of these unique and challenging PFO-associated conditions.
PMID: 35847406
ISSN: 0974-2069
CID: 5278822

Short-Segment Type B Interrupted Aortic Arch Presenting With Subarachnoid Hemorrhage With Subsequent Primary Percutaneous Repair

Ramachandran, Abhinay; Argilla, Michael; Saharan, Sunil; Halpern, Dan; Small, Adam
This report describes a young adult man presenting with subarachnoid hemorrhage secondary to an intracranial aneurysm who was found to have a short-segment type B interrupted aortic arch. We describe the clinical presentation, evaluation, and management of this patient and highlight imaging findings and percutaneous repair of the aneurysm and interrupted aortic arch. (Level of Difficulty: Intermediate.).
PMID: 34729511
ISSN: 2666-0849
CID: 5038122

Modified Warden operation using aortic homograft [Case Report]

Kumar, T K Susheel; Chen, David; Halpern, Dan; Bhatla, Puneet; Saharan, Sunil; Argilla, Michael; Mosca, Ralph
PMID: 34318041
ISSN: 2666-2507
CID: 4949602


Decarlo, D; Saharan, S; Argilla, M
Background A right aortic arch is present in 18% of patients with congenital heart disease, and is usually associated with Tetralogy of Fallot or truncus arteriosus. Its incidence in D-TGA ranges from <1% to 12% in the literature. An isolated left subclavian, defined as a left subclavian artery that is disconnected from the aorta and arises from a branch pulmonary artery, is a rare right aortic arch anomaly. It is typically associated with Tetralogy of Fallot and truncus arteriosus, and exceedingly rare in cases of D-TGA. Case A full-term neonate with prenatal diagnosis of D-TGA with VSD was born at our institution. At birth, the baby was vigorous but with low oxygen saturation in the right hand (60s). The baby was started on continuous positive airway pressure at 100% FiO2 as well as a prostaglandin infusion and transferred to the NICU. Our initial echocardiogram confirmed the diagnosis of D-TGA with moderate-size muscular VSD as well as a right-sided aortic arch. On echocardiogram there appeared to be an aberrant left subclavian artery that could not be imaged definitively. The baby was taken to the catheterization lab the next day for balloon atrial septostomy and angiograms to better delineate arch anatomy. Angiography showed a left subclavian artery arising from the left pulmonary artery Decision-making In the case of our patient, the typical practice of measuring pre- and post-ductal saturations in the right and left hands, respectively, did not yield the "classic" picture of reverse differential cyanosis. We opted to monitor pre-ductal saturations on the right earlobe to better monitor saturations. Conclusion It is important to consider variability in arch sidedness and aortic arch anatomy when evaluating a newborn with D-TGA. We recommend checking for a pre-ductal saturation on one of the ears, if feasible, as this data is more representative of the arterial saturation of the cerebral blood vessels. Another important clinical consideration with an isolated subclavian artery with or without TGA is the subclavian steal phenomenon. When pulmonary vascular resistance drops, flow will preferentially go from the systemic circulation into the pulmonary circulation, reducing flow in vertebral arteries.
ISSN: 1558-3597
CID: 4380882

Belhassen tachycardia in a 19-month-old child [Case Report]

Huang, Jennifer H; Saharan, Sunil; McCammond, Amy; Balaji, Seshadri
PMID: 25304921
ISSN: 1097-6833
CID: 1790552

Preoperative platelet dysfunction predicts blood product transfusion in children undergoing cardiac surgery

Zubair, M Mujeeb; Bailly, David K; Lantz, Gurion; Sunstrom, Rachel E; Saharan, Sunil; Boshkov, Lynn K; Sochacki, Paul; Roger Hohimer, A; Lasarev, Michael R; Langley, Stephen M
OBJECTIVES: Excessive bleeding can be a problem during or after cardiac surgery. While cardiopulmonary bypass-associated platelet dysfunction is an important inducer of coagulopathy, preoperative platelet dysfunction can also contribute to this bleeding. We investigated the relationship between preoperative platelet dysfunction and transfusion of blood products given to children undergoing cardiac surgery. METHODS: The platelet function analyser test measures platelet function in vitro by aspirating blood through a small standard hole (creating high shear) in a collagen membrane infused with a platelet agonist. The time taken to form a platelet plug is known as closure time and prolonged closure time (CT) indicates platelet dysfunction. Three hundred and thirty-eight children who had undergone surgery with cardiopulmonary bypass between 2008 and 2012 were included. The volume of red blood cells and fresh-frozen plasma transfused was recorded. The relationship between closure time and transfusion requirements was analysed using linear and logistic regression. RESULTS: Patients with prolonged closure time had greater odds of getting red blood cells and fresh-frozen plasma transfusions compared with patients with normal closure time (P <0.01). On univariate analysis, age, weight, haematocrit, cardiopulmonary bypass time, Risk Adjustment for Congenital Heart Surgery score and closure time were associated with increased odds of red blood cells and fresh-frozen plasma transfusion in the operation theatre (P <0.05). However, when logistic multivariable regression analysis was applied, only age, cardiopulmonary bypass time and closure time remained as significant predictive factors for transfusion. CONCLUSIONS: In children who have undergone cardiac surgery, when age and cardiopulmonary bypass time are accounted for, a prolonged preoperative closure time is significantly associated with increased odds of red blood cells and fresh-frozen plasma transfusion in the operation theatre. This may have implications for planning and utilization of blood products.
PMID: 25281704
ISSN: 1569-9285
CID: 1790542

Cardiovascular collapse during amiodarone infusion in a hemodynamically compromised child with refractory supraventricular tachycardia

Saharan, Sunil; Balaji, Seshadri
We describe a 7-week-old female infant who presented with refractory supraventricular tachycardia (SVT). During amiodarone infusion, she developed hypotension and cardiac arrest requiring extracorporeal membrane oxygenation (ECMO) support. After successful control of SVT using procainamide infusion, she was weaned from ECMO and discharged home on oral flecainide. We conclude that infants with acidosis, ventricular dysfunction, and prolonged refractory SVT may poorly tolerate intravenous amiodarone.
PMID: 25684888
ISSN: 0974-2069
CID: 1790532