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Joint Preserving Treatments for Thumb CMC Arthritis

Spielman, Amanda F; Sankaranarayanan, Sriram; Lessard, Anne-Sophie
Trapezium resection with or without tendon suspension arthroplasty has been considered the gold standard surgical treatment for thumb carpometacarpal joint osteoarthritis (CMCJ OA). However, the removal of the trapezium may result in subsidence or shortening of the first metacarpal axis. Resection may also lead to reduced pinch strength and thumb instability. Joint preservation techniques may be used in early stages of CMCJ OA to promote pain relief, return to function, and delay more invasive procedures such as a trapezium resection.
PMID: 35465935
ISSN: 1558-1969
CID: 5205442

Upper extremity necrotizing fasciitis in a Covid-19 patient [Case Report]

Sankaranarayanan, Sriram; Spielman, Amanda F; Lessard, Anne-Sophie; Husain, Tarik
The novel COVID-19 virus has resulted in an immense burden in healthcare throughout the world. In addition to respiratory complications, COVID-19 has been associated with hypercoagulability and ischemic changes. We report a case of a patient with COVID-19 who presented with a rapidly progressing necrotizing fasciitis treated in our institution.
PMID: 35083369
ISSN: 2332-0885
CID: 5154622

The critical shoulder angle (CSA) in glenohumeral osteoarthritis: Does observer experience affect measurement reliability on plain radiographs?

Sankaranarayanan, Sriram; Saks, Benjamin R; Holtzman, Ari J; Tabeayo, Eloy; Cuomo, Frances; Gruson, Konrad I
Background/UNASSIGNED:The critical shoulder angle (CSA) has been associated with full-thickness rotator cuff tears both in the presence and absence of glenohumeral arthritis. It is unclear whether the CSA can be reliably measured from plain radiographs of concentric glenohumeral osteoarthritis amongst examiners at differing levels of training. Methods/UNASSIGNED:We retrospectively reviewed the radiographs of consecutive patients who underwent shoulder arthroplasty for glenohumeral osteoarthritis. The CSA was measured on a standardized AP scapular view at baseline and then 4 weeks later by fellowship-trained orthopaedic surgeons, a shoulder fellow and a senior orthopaedic resident. Grade of arthritis was categorized using the Samilson and Prieto method. The inter- and intra-observer reliability was then determined for all examiners, as well as for increasing severity of radiographic arthritis. The relationship between the CSA and grade of arthritis was assessed. Results/UNASSIGNED:There were 166 included patients comprised of 104 females (63%) and 62 males (37%) with a mean age of 65.9 ± 10.4 years. The inter- and intra-observer reliability for measuring the CSA amongst all examiners was found to be excellent, with an intra-class coefficient (ICC) of >0.9 (p < 0.0001). The ICC remained excellent even amongst radiographs with more advanced arthritis. Furthermore, there was a weak, inverse relationship between the grade of arthritis and the CSA (r = -0.377, p < 0.005). Conclusion/UNASSIGNED:The CSA can reliably be measured by examiners at varying levels of orthopaedic training, even with more advanced radiographic glenohumeral osteoarthritis. Level of evidence: Level III (Prognostic).
PMID: 32419757
ISSN: 0972-978x
CID: 4482592

Recurrent and persistent carpal tunnel syndrome: "Triple-therapy approach"

Spielman, Amanda F; Sankaranarayanan, Sriram; Skowronski, Piotr; Lessard, Anne-Sophie; Panthaki, Zubin
Background/UNASSIGNED:Various procedures have been described for patients undergoing a revision carpal tunnel release. These can include repeat open decompression with external or internal neurolysis, tenosynovectomy, endoscopic release, various flap techniques, saphenous vein wrapping and use of prosthetic implants. This study reports a case series of 30 consecutive patients who underwent revision carpal tunnel release at single institution from 2012 to 2018. Our surgical plan in all the patients involved a combination of these three techniques (triple therapy approach): neurolysis (external or internal) and tenosynovectomy, collagen matrix conduit wrap (NeuraWrap; Integra LifeSciences or Axoguard Nerve Protector, AxoGen Inc), and hypothenar fat flap. Materials and methods/UNASSIGNED:-test. All statistical analyses were performed with SPSS 20 (IBM, Chicago, IL). Results/UNASSIGNED:Patient reported measures of resolution of symptoms and VAS scores documented at 3 months. Of the 30 patients who underwent surgery for persistent or recurrent carpal tunnel syndrome, symptoms resolved completely in 25 patients. 2 patients were lost to follow up. 3 patients showed no improvement. The mean preoperative VAS score was 4.37 and declined to 1.23 after surgery (P < .0001). Conclusion/UNASSIGNED:Our study demonstrates that a combination of neurolysis and tenosynovectomy along with a nerve wrap and hypothenar fat flap should be considered in patients presenting with recurrent or persistent carpal tunnel syndrome.
PMID: 33041567
ISSN: 0972-978x
CID: 4637152

Patient Preferences for Plain Radiographs in the Setting of Atraumatic Shoulder Pain: Which Factors Influence Their Decision?

Lyudmer, Michael; Levy, Benjamin J; Holtzman, Ari J; Sankaranarayanan, Sriram; Tabeayo, Eloy; Gruson, Konrad I
INTRODUCTION/BACKGROUND:Plain radiographs of the shoulder are routinely obtained for patients presenting with atraumatic shoulder pain, although the diagnostic utility of this imaging modality is unclear. Despite this, patients often prefer to obtain radiographs and may associate them with a more satisfactory visit. METHODS:New patients presenting with atraumatic shoulder pain were provided with information regarding the potential advantages and disadvantages of plain radiographs as part of their visit. Patients then decided whether to receive radiographs and baseline patient demographics were collected. A detailed physical examination and history was performed by a fellowship-trained provider, and a preliminary diagnosis and tentative treatment plan was formulated. The radiographs were then reviewed to determine whether the diagnosis and treatment plan was altered by addition of the radiographs. Patients who opted for radiographs then reported whether they felt the radiographs aided in diagnosis and treatment and whether the addition of the radiograph influenced their visit satisfaction. RESULTS:A total of 220 patients met the inclusion criteria. Overall, 121 patients (55%) requested a radiograph. The mean age was 57.1 ± 16.1 years (range, 18 to 91 years). Lack of bachelor's degree (odds ratio [OR], 2.8; 95% confidence interval [CI], 1.2 to 6.2; P = 0.01), lack of previous contralateral shoulder pain (OR, 4.0; 95% CI, 2.0 to 8.2; P = 0.0001), and lack of a previous shoulder radiograph (OR, 8.4; 95% CI, 4.1 to 16.9; P < 0.0001) or MRI within the last 6 months (OR, 6.2; 95% CI, 1.4 to 26.8; P = 0.01) were independently associated with patient preference to obtain radiographs for atraumatic shoulder pain. Of the 121 patients who requested radiographs, 117 (96.7%) felt that radiographs improved their satisfaction. DISCUSSION/CONCLUSIONS:Patients who obtained radiographs overwhelmingly reported its importance in improving visit satisfaction and diagnostic accuracy. Given the increasing emphasis on shared decision making, further study of patient factors influencing the decision to obtain routine radiographs will lead to more efficient practice management and potentially improved patient satisfaction. LEVEL OF EVIDENCE/METHODS:Level II (Diagnostic).
PMID: 31415295
ISSN: 1940-5480
CID: 4482572

The utility of obtaining routine hematological laboratory values following an anterior cervical diskectomy and fusion

Manning, Blaine T; Sankaranarayanan, Sriram; Hassanzadeh, Hamid; Nandyala, Sreeharsha V; Marquez-Lara, Alejandro; Naqvi, Abbas; Elboghdady, Islam M; Noureldin, Mohamed; Singh, Kern
STUDY DESIGN/METHODS:Retrospective analysis of a prospectively maintained database. OBJECTIVE:To characterize the utility of obtaining routine postoperative laboratory studies after an anterior cervical diskectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA/BACKGROUND:ACDF is typically associated with minimal blood loss and morbidity. However, at many institutions, postoperative laboratory studies are conducted routinely. This study aims to characterize the utility of these tests in the postoperative setting. METHODS:A retrospective analysis of a prospectively maintained database of 332 patients who underwent an ACDF for degenerative cervical spine disease between 2007 and 2014 was performed. Patients with a concurrent corpectomy, posterior fusion, or revision procedure were excluded. Patient demographics, comorbidities, visual analogue scale scores, surgical and hospitalization parameters, complications, and transfusion volumes were assessed. The patient's postoperative laboratory studies were compared with preoperative values. Statistical analysis was performed with independent sample T tests for continuous variables and χ analysis for categorical data. An α level of less than 0.05 denoted statistical significance. RESULTS:A total of 332 patients were included with a mean age of 51.1 ± 11.7 years. The overall mean procedural time, estimated blood loss, and length of stay were 60.0 ± 30.1 minutes, 69.4 ± 36.2 mL, and 40.2 ± 20.3 hours, respectively. Overall, 98.1% of patients demonstrated radiographical arthrodesis at 1 year. After a 1- or 2-level ACDF, the postoperative hemoglobin, hematocrit, blood urea nitrogen, sodium, and calcium levels significantly decreased, whereas glucose and chloride levels increased when compared with the preoperative values (P < 0.05). In addition, the 1-level ACDF cohort was also associated with reduced postoperative potassium level (P < 0.05). However, none of the patients required intraoperative or postoperative blood product transfusion or demonstrated evidence of postoperative anemia. Two patients (0.89%) required postoperative potassium replacement based upon laboratory values alone without clinical symptomatology. There were no complications that were related to the patient's hemodynamic status or fluid and electrolyte balance. CONCLUSION/CONCLUSIONS:In the majority of cases after an ACDF, no action was taken n the basis of the patient's routine postoperative laboratory data. None of the patients required blood product transfusion, whereas only 0.89% (n = 2) required potassium replacement for laboratory anomalies without clinical symptomatology. These findings suggest that routine postoperative complete blood counts do not change postoperative management after an ACDF unless intraoperative bleeding is noted or the patient carries risk factors for postoperative hemorrhagic anemia. LEVEL OF EVIDENCE/METHODS:3.
PMID: 25010100
ISSN: 1528-1159
CID: 4482542

Cost analysis of incidental durotomy in spine surgery

Nandyala, Sreeharsha V; Elboghdady, Islam M; Marquez-Lara, Alejandro; Noureldin, Mohamed N B; Sankaranarayanan, Sriram; Singh, Kern
STUDY DESIGN/METHODS:Retrospective database analysis. OBJECTIVE:To characterize the consequences of an incidental durotomy with regard to perioperative complications and total hospital costs. SUMMARY OF BACKGROUND DATA/BACKGROUND:There is a paucity of data regarding how an incidental durotomy and its associated complications may relate to total hospital costs. METHODS:The Nationwide Inpatient Sample database was queried from 2008 to 2011. Patients who underwent cervical or lumbar decompression and/or fusion procedures were identified, stratified by approach, and separated into cohorts based on a documented intraoperative incidental durotomy. Patient demographics, comorbidities (Charlson Comorbidity Index), length of hospital stay, perioperative outcomes, and costs were assessed. Analysis of covariance and multivariate linear regression were used to assess the adjusted mean costs of hospitalization as a function of durotomy. RESULTS:The incidental durotomy rate in cervical and lumbar spine surgery is 0.4% and 2.9%, respectively. Patients with an incidental durotomy incurred a longer hospitalization and a greater incidence of perioperative complications including hematoma and neurological injury (P < 0.001). Regression analysis demonstrated that a cervical durotomy and its postoperative sequelae contributed an additional adjusted $7638 (95% confidence interval, 6489-8787; P < 0.001) to the total hospital costs. Similarly, lumbar durotomy contributed an additional adjusted $2412 (95% confidence interval, 1920-2902; P < 0.001) to the total hospital costs. The approach-specific procedural groups demonstrated similar discrepancies in the mean total hospital costs as a function of durotomy. CONCLUSION/CONCLUSIONS:This analysis of the Nationwide Inpatient Sample database demonstrates that incidental durotomies increase hospital resource utilization and costs. In addition, it seems that a cervical durotomy and its associated complications carry a greater financial burden than a lumbar durotomy. Further studies are warranted to investigate the long-term financial implications of incidental durotomies in spine surgery and to reduce the costs associated with this complication. LEVEL OF EVIDENCE/METHODS:3.
PMID: 24859577
ISSN: 1528-1159
CID: 4482532

Incidence and risk factors for postoperative ileus following anterior, posterior, and circumferential lumbar fusion

Fineberg, Steven J; Nandyala, Sreeharsha V; Kurd, Mark F; Marquez-Lara, Alejandro; Noureldin, Mohamed; Sankaranarayanan, Sriram; Patel, Alpesh A; Oglesby, Matthew; Singh, Kern
BACKGROUND CONTEXT/BACKGROUND:Postoperative ileus is a known complication of surgery. The incidence and risk factors for ileus after lumbar fusion surgery is not well characterized. PURPOSE/OBJECTIVE:To determine rates of postoperative ileus, a population-based database was analyzed to identify incidence, mortality, and risk factors associated with anterior (ALF), posterior (PLF), and combined anterior/posterior (APLF) lumbar fusions. STUDY DESIGN/METHODS:This was a retrospective database analysis. PATIENT SAMPLE/METHODS:The sample consisted of 220,522 patients from the Nationwide Inpatient Sample (NIS) database. OUTCOME MEASURES/METHODS:Outcome measures were incidence of postoperative ileus, length of stay (LOS), in-hospital costs, and mortality. METHODS:Data from the NIS were obtained from 2002 to 2009. Patients undergoing ALF, PLF, and APLF for degenerative pathologies were identified and the incidence of postoperative ileus was assessed. Patient demographics, Charlson comorbidity index (CCI), LOS, costs, and mortality were assessed. SPSS v.20 was used to detect statistical differences between groups and perform logistic regression analyses to identify independent predictors of postoperative ileus. A p value less than .001 denoted significance. RESULTS:A total of 220,522 lumbar fusions were identified in the United States from 2002 to 2009. There were 19,762 ALFs, 182,801 PLFs, and 17,959 APLFs. The incidence of postoperative ileus was increased in ALFs over PLFs (74.9 vs. 26.0 per 1,000; p<.001). Within PLF and APLF groups, CCI scores were increased in the presence of postoperative ileus (p<.001). Across cohorts, patients with postoperative ileus demonstrated greater LOS and costs (p<.001). PLF-treated patients with postoperative ileus demonstrated increased mortality (p<.001). Independent predictors of postoperative ileus included male gender, 3+ fusion levels, alcohol abuse, anemia, fluid/electrolyte disorders, and weight loss (p<.001). CONCLUSIONS:The results of our study demonstrate increased incidence of postoperative ileus associated with anterior approaches for lumbar fusion. Across cohorts, postoperative ileus was associated with increased LOS and costs. To determine the mortality and resource use associated with postoperative ileus, we recommend preoperatively identifying and treating modifiable risk factors, especially when an anterior approach is used.
PMID: 24184650
ISSN: 1878-1632
CID: 4482492

Body mass index as a predictor of complications and mortality after lumbar spine surgery

Marquez-Lara, Alejandro; Nandyala, Sreeharsha V; Sankaranarayanan, Sriram; Noureldin, Mohamed; Singh, Kern
STUDY DESIGN/METHODS:Retrospective analysis. OBJECTIVE:A national population-based database was analyzed to characterize the risks of postoperative complications and mortality associated with the patient's body mass index (BMI) after lumbar spinal surgery. SUMMARY OF BACKGROUND DATA/BACKGROUND:Obesity has been associated with greater perioperative complications and worsened surgical outcomes after lumbar spinal surgery. However, the stratified BMI risks of postoperative complications relative to normal weight patients have not been well characterized. METHODS:The American College of Surgeons National Surgical Quality Improvement Program database was queried to identify patients who underwent lumbar spinal surgery between 2006 and 2011. Patients were stratified into BMI cohorts: normal (18.5-24.99 kg/m), overweight (25.00-29.99 kg/m), class 1 (30.00-34.99 kg/m), class 2 (35.00-39.99 kg/m), and class 3 (≥40 kg/m) obesity. Preoperative patient characteristics and perioperative outcomes were assessed. The relative risks of 30-day postoperative complications and mortality for each BMI cohort were calculated in reference to the normal weight cohort using a 95% confidence interval. RESULTS:A total of 24,196 patients underwent lumbar spine surgery between 2006 and 2011 of which 19,195 (79.3%) were overweight or obese. The risk for deep vein thrombosis increased beginning with overweight patients and compounded for the subsequent obesity classes. The risk for superficial wound infection and pulmonary embolism increased beginning with the class 1 obesity cohort. Furthermore, the relative risk increase for urinary tract infection, acute renal failure, and sepsis was significantly increased only among class 3 obesity patients. Lastly, there was no relative risk increase in 30-day mortality in any cohort after lumbar spine surgery. CONCLUSION/CONCLUSIONS:Overweight and obese patients demonstrated an increased risk of postoperative complications relative to normal weight patients. Despite these findings, a BMI 25 kg/m or more was not associated with a greater risk of mortality. Further studies are warranted to characterize the impact of postoperative complications associated with overweight and obese patients on hospital resource utilization and costs after lumbar spine surgery.
PMID: 24480950
ISSN: 1528-1159
CID: 4482502

Incidence, risk factors, and outcomes of postoperative airway management after cervical spine surgery

Nandyala, Sreeharsha V; Marquez-Lara, Alejandro; Park, Daniel K; Hassanzadeh, Hamid; Sankaranarayanan, Sriram; Noureldin, Mohamed; Singh, Kern
STUDY DESIGN/METHODS:Retrospective database analysis. OBJECTIVE:To identify the incidence and risk factors for a prolonged intubation or an unplanned reintubation after cervical spine surgery (CSS). SUMMARY OF BACKGROUND DATA/BACKGROUND:Patients who undergo CSS occasionally require prolonged mechanical ventilation or an unplanned reintubation for airway support. Despite the potential severity of these complications, there are limited data in the published literature addressing this issue. METHODS:The American College of Surgeons National Surgical Quality Improvement Program database was queried to identify patients who underwent a CSS. Patients who required a prolonged intubation more than 48 hours or an unplanned reintubation after CSS were compared with those without airway compromise. Preoperative patient characteristics, intraoperative variables, hospital length of stay, 30-day complication rates, and mortality were compared between the cohorts. An α ≤ 0.001 denoted statistical significance. A multivariate regression model was used to identify independent predictors for a prolonged intubation and an unplanned reintubation. RESULTS:A total of 8648 cervical spine procedures were identified from 2006 to 2011 of which 54 patients (0.62%) required prolonged ventilation and 56 patients (0.64%) underwent a postoperative reintubation. Patients who required postoperative airway management were older and demonstrated a greater comorbidity burden (P < 0.001). In addition, the affected cohorts demonstrated a significantly greater rate of readmissions, reoperations, postoperative complications, and mortality (P < 0.001). Regression analysis identified the independent predictors for prolonged ventilation to include a history of cardiac disease and dialysis along with a low preoperative albumin level (P < 0.05). Similarly, the independent risk factors for a postoperative reintubation included a history of recent weight loss more than 10%, recent operation within 30 days, low preoperative hematocrit, and a high serum creatinine (P < 0.05). CONCLUSION/CONCLUSIONS:Postoperative airway management is a rare complication after CSS. A prolonged intubation and an unplanned reintubation carry a greater rate of postoperative complications and mortality. High-risk patients should be identified prior to surgery to mitigate the risk factors for postoperative airway compromise. LEVEL OF EVIDENCE/METHODS:3.
PMID: 24480959
ISSN: 1528-1159
CID: 4482522