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52


Ghrelin Resting Energy Expenditure Number (GREEN) Study [Meeting Abstract]

Weinshel, Elizabeth; Chua, Deborah; Fielding, George; Lofton, Holly F; Ren-Fielding, Christine; Schwack, Bradley
ISI:000363715905063
ISSN: 1572-0241
CID: 1854422

Single-stage versus 2-stage sleeve gastrectomy as a conversion after failed adjustable gastric banding: 30-day outcomes

Obeid, Nabeel R; Schwack, Bradley F; Kurian, Marina S; Ren-Fielding, Christine J; Fielding, George A
BACKGROUND: Sleeve gastrectomy (SG) is being performed as a conversion after adjustable gastric banding (AGB), often in a single stage. However, some argue that it should be performed in 2 stages to improve safety. Few studies compare complications between 1-stage and 2-stage procedures. Our aim is to compare the 30-day complication rates among these two groups. METHODS: We retrospectively reviewed patients converted from AGB to SG between 8/2008 and 10/2013 and compared patients undergoing 1-stage and 2-stage techniques. Primary outcome was overall 30-day adverse event rate (postoperative complication, readmission, or reoperation). Secondary outcomes included operating room (OR) time, length of stay (LOS), leak, infection, and bleeding rates, as well as mortality. RESULTS: A total of 83 patients underwent SG after band removal; three were excluded due to short follow-up, leaving 60 1-stage and 20 2-stage. Mean time from band removal to SG for 2-stage was 438 days. Demographics, intraoperative technique (bougie size, staple reinforcement, oversewing staple line, and leak test), and mean follow-up were not statistically different. Mean OR time (132.1 min 1-stage vs. 127.8 min 2-stage, p = 0.702) and LOS (3.1 vs. 2.4 days, p = 0.676) were similar. Overall 30-day adverse event rate was 12 % for 1-stage versus 15 % for 2-stage procedures (p = 0.705). Differences in 30-day readmission (8 vs. 5 %) and reoperation (5 vs. 0 %) were not statistically significant (p = 0.999 and 0.569, respectively). Leak (3 vs. 0 %, p = 0.999), abscess (2 vs. 5 %, p = 0.440), and bleeding rates (2 vs. 0 %, p = 0.999) were not different. There were no deaths. CONCLUSIONS: SG performed as a conversion after AGB is safe and feasible. Our findings indicate no statistical difference in 30-day outcomes when performed in 1 or 2 stages. Future studies with larger sample sizes are necessary to further investigate these differences.
PMID: 24902818
ISSN: 0930-2794
CID: 1033302

Sustained Weight Loss After Gastric Banding Revision for Pouch-Related Problems

Beitner, Melissa M; Ren-Fielding, Christine J; Kurian, Marina S; Schwack, Bradley F; Skandarajah, Anita R; Thomson, Benjamin N; Baxter, Andrew R; Leon Pachter, H; Fielding, George A
OBJECTIVE:: To assess the impact of revisional surgery after laparoscopic adjustable gastric banding (LAGB) on weight loss at 12 and 24 months. BACKGROUND:: There is no uniform consensus as to the optimal procedure for patients requiring revision after LAGB. Few studies address the issue of weight loss after band salvage procedures, despite this being a critical factor in deciding which reoperative procedure to choose. METHODS:: A retrospective analysis was conducted of adult patients who underwent LAGB from January 1, 2001 to June 30, 2009 at a single institution. Patients who required revision for pouch-related problems including band slippage, pouch dilation, and hiatal hernia were studied. Demographic data, body mass index (BMI), percentage excess weight loss (% EWL), and operative details were recorded. Weights were recorded at 12 and 24 months after revision. These were compared with initial weight, weight before revision, and weight in patients who did not have a reoperation. RESULTS:: Of 3876 patients, 390 patients were included in analysis of weight outcomes after revision. The procedure-related mortality was 0%. Early (30-day) complications occurred in 0.5%, late complications (erosion) in 0.5%, and 29 patients (7.4%) required a second revision. For patients undergoing revision, the initial weight was 124.06 +/- 21.28 kg and BMI was 44.80 +/- 6.12 kg/m. At reoperation, weight was 89.18 +/- 20.51 kg, BMI was 32.25 +/- 6.50 kg/m and, %EWL was 54.13 +/- 21.80%. Twelve months postrevision, weight was 92.24 +/- 20.22 kg, BMI was 33.32 +/- 6.41 kg/m, and %EWL was 48.81 +/- 22.71%. Weight was 92.42 +/- 19.91 kg, BMI was 33.53 +/- 6.25 kg/m, and %EWL was 47.50 +/- 22.91% twenty-four months postrevision. CONCLUSIONS:: Reoperation for pouch-related problems after LAGB is safe and effective. Weight loss is maintained after reoperation.
PMID: 24441823
ISSN: 0003-4932
CID: 902302

Salvage Laparoscopic Adjustable Gastric Banding After Failed Roux-en Y Gastric Bypass [Meeting Abstract]

Loy, John; Youn, Heekoung; Schwack, Bradley; Kurian, Marina; Fielding, George; Ren-Fielding, Christine
ISI:000331797500020
ISSN: 0007-1323
CID: 867472

Resolution of Non-Alcoholic Fatty Liver Disease And Metabolic Syndrome In Adolescents Undergoing Laparoscopic Adjustable Gastric Banding (LAGB) [Meeting Abstract]

Loy, John; Youn, Heekoung; Schwack, Bradley; Kurian, Marina; Ren-Fielding, Christine; Fielding, George
ISI:000331797500026
ISSN: 0007-1323
CID: 867462

Comparing revision procedures after laparoscopic adjustable gastric band failure: Gastric bypass vs. Sleeve gastrectomy [Meeting Abstract]

Schwack, B F; Loy, J; Youn, H; Kurian, M S; Ren, Fielding C J; Fielding, G A
Aims: Laparoscopic adjustable gastric banding (LAGB), sleeve gastrectomy (LSG) and roux-en-y gastric bypass (LRYGB) are safe and effective bariatric procedures. Weight loss failure occurs and revision procedures are often performed. Our aim is to review our experience converting LAGB failures into LRYGB and LSG. Methods: This is a retrospective review of 121 patients (2008-2012) who underwent bariatric revision procedures after weight loss failure or intolerance to LAGB. We compared patients revised into LRYGB and LSG. Parameters reviewed include 30-day readmissions, reoperations, operating time, length of stay (LOS), and percent excess weight loss (%EWL) from primary and secondary procedures. Four of 91 LAGB to LRYGB and 3 of 30 LAGB to LSG underwent open procedures. Results: Data on 121 revised patients was assessed 91 LAGB to LRYGB (Group 1) and 30 LAGB to LSG (Group 2). Group 1's average OR time was 168.29 min; Group 2's was 146.24 min (p = .031). Group 1's mean LOS was 4.53 days while Group 2's was 3.9 days (p = 0.628). Group 1 patients experienced 12 of 91 (13.19%) bypass related reoperations; Group 2 patients experienced 1 of 30 (3.33%) sleeve related reoperations (p = .133). Group 1 patients had 10 30-day readmissions (10.99%); Group 2 had 2 30-day readmissions (6.67%) (p = .496). Regarding the first year after conversion, %EWL from the revision was reviewed. The %EWL for the bypass versus sleeve group was 24.45 vs. 22.50 at 3 months, 44.22 vs 24.77 at 6 months, and 47.16 vs 34.12 at 12 months (p values respectively: 0.406, 0.002, 0.179). Of note, %EWL from pre-LAGB was: (bypass vs sleeve) 36.96 vs. 22.5 at 3 months, 49.07 vs 40.27 at 6 months, and 54.78 vs. 34.12 at a year. Conclusions: For patients exhibiting weight loss failure or intolerance to LAGB, both LSG and LRYGB are safe options with comparable length of stay, readmissions, and reoperations. Operative time is significantly shorter with conversion to LSG. Additional weight loss from the revision procedure is moderate in all ca!
EMBASE:71478337
ISSN: 0930-2794
CID: 1058222

Safety and efficacy of laparoscopic adjustable gastric banding in patients aged seventy and older

Loy, John J; Youn, Heekoung A; Schwack, Bradley; Kurian, Marina S; Fielding, George A; Ren-Fielding, Christine J
BACKGROUND: Life expectancy is increasing, with more elderly people categorized as obese. The objective of this study was to assess the effects of laparoscopic adjustable gastric banding (LAGB) on patients aged>/=70 years. METHODS: This was a retrospective analysis of patients aged>/=70 years who underwent LAGB at our university hospital between 2003 and 2011. The data included age, weight, body mass index (BMI), and percentage excess weight loss (%EWL) obtained before and after gastric banding. Operative data, length of stay, postoperative complications, and resolution of co-morbid conditions were also analyzed. RESULTS: Fifty-five patients aged>/=70 years (mean 73 years) underwent gastric banding between 2003 and 2012. Mean preoperative weight and BMI were 123 kilograms and 45 kg/m(2), respectively. On average, each patient had 4 co-morbidities preoperatively, with hypertension (n = 49; 86%), dyslipidemia (n = 40; 70%), and sleep apnea (n = 31; 54%) being the most common. Mean operating room (OR) time was 49 minutes, with all patients discharged within 24 hours. There was 1 death at 4 years from myocardial infarction, no intensive care unit admissions, and no 30-day readmissions. Mean %EWL at 1, 2, 3, 4, and 5 years was 36 (+/-12.7), 40 (+/-16.4), 42 (+/-19.2), 41 (+/-17.1), 50 (+/-14.9), and 48 (+/-22.6), respectively. Follow-up rates ranged from 55/55 (100%) at 6 months to 7/9 (78%) of eligible patients at 5 years and 2/2 (100%) at 8 years. Complications included 1 band slip at year 5, 1 band removed for intolerance, and 1 port site hernia. The resolution of hypertension, dyslipidemia, sleep apnea, lower back pain, and non-insulin-dependent diabetes was 27%, 28%, 35%, 31%, and 35%, respectively. CONCLUSIONS: LAGB as a primary treatment for obesity in carefully selected patients aged>/=70 can be well tolerated and effective with moderate resolution of co-morbid conditions and few complications.
PMID: 24582414
ISSN: 1550-7289
CID: 867052

Location and number of sutures placed for hiatal hernia repair during laparoscopic adjustable gastric banding: does it matter?

Obeid, Nabeel R; Deese-Laurent, Spencer; Schwack, Bradley F; Youn, Heekoung; Kurian, Marina S; Ren-Fielding, Christine; Fielding, George A
BACKGROUND: It has been demonstrated that hiatal hernia repair (HHR) during laparoscopic adjustable gastric banding (LAGB) decreases the rate of reoperation. However, the technical aspects (location and number of sutures) are not standardized. It is unknown whether such technical details are associated with differing rates of reoperation for band-related problems. METHODS: A retrospective analysis was performed from a single institution, including 2,301 patients undergoing LAGB with HHR from July 1, 2007 to December 31, 2011. Independent variables were number and location of sutures. Data collected included demographics, operating room (OR) time, length of stay (LOS), follow-up time, postoperative BMI/%EWL, and rates of readmission/reoperation. Statistical analyses included ANOVA and Chi squared tests. Kaplan-Meier, log-rank, and Cox regression tests were used for follow-up data and reoperation rates, in order to account for differential length of follow-up and confounding variables. RESULTS: There was no difference in length of follow-up among all groups. The majority of patients had one suture (range 1-6; 55 %). Patients with fewer sutures had shorter OR time (1 suture 45 min vs. 4+ sutures 56 min, p < 0.0001). LOS, 30-day readmission, band-related reoperation, and postop BMI/%EWL were not statistically significant. Anterior suture placement (vs. posterior vs. both) was most common (61 %). OR time was shorter in those with anterior suture (41 min vs. posterior 56 min vs. both 59 min, p < 0.0001). Patients with posterior suture had a longer LOS (84 % 1 day vs. anterior 74 % 1 day vs. both 74 % 1 day, p < 0.0001). There was no difference in 30-day readmission, band-related reoperation, and postoperative BMI/%EWL. CONCLUSIONS: Patients with fewer or anterior sutures have shorter OR times. However, 30-day readmission, band-related reoperation, and postoperative weight loss were unaffected by number or location of suture. The technical aspects of HHR did not appear to be associated with readmission or reoperation, and therefore a standardized approach may not be necessary.
PMID: 24061619
ISSN: 0930-2794
CID: 746002

Update on Salvage Gastric Banding for Failed Roux-en-Y Gastric Bypass [Meeting Abstract]

Loy, J.; Youn, H.; Schwack, B.; Fielding, G.; Ren-Fielding, C.
ISI:000321389200636
ISSN: 0960-8923
CID: 472182

Conversion of failed laparoscopic adjustable gastric banding to revisional bypass: Results from 76 cases [Meeting Abstract]

Bedrosian, A S; Lee, T M; Youn, H A; Ren, Fielding C; Schwack, B F; Kurian, M S; Fielding, G A
Aims: Laparoscopic adjustable gastric banding (LAGB) has gained popularity as a safe, reversible surgical treatment for morbid obesity. However, there are few studies and no consensus on revisional bariatric surgery for those patients in whom banding has failed. We analyzed results of conversion from LAGB to Roux-en-Y gastric bypass or biliopancreatic diversion in one high-volume center. Methods: A single-institution retrospective review was conducted on patients who had undergone conversion of LGB to a revisional bypass procedure during the time period January 2003 through November 2011. Data on patient demographics, surgical technique, pre- and post-operative complications, and weight loss (body mass index [BMI] and percent excess weight loss [%EWL]) were collected and analyzed. Results: We identified 76 patients at our institution who underwent conversion from LAGB to Roux-en-Y gastric bypass (RYGB; n = 62), biliopancreatic diversion (BPD; n = 12), or biliopancreatic diversion with duodenal switch (BPD/DS; n = 2). 69 of the 76 conversions (90.8%) were completed laparoscopically. 29/76 (38.2%) had required additional surgery prior to conversion for band-related complications including slippage, erosion, port migration, hiatal hernia, bowel obstruction, or leakage; all occurred at >;30 days. After conversion, the rate of complications requiring hospitalization was 27.6% (21/76); 14.5% (11/76) occurred at<30 days. There was one mortality. Mean time from band placement to conversion was 1439 +/- 661.4 days (range 245-3140). At time of conversion, mean BMI was 44.4 +/- 6.6 kg/ m2, and mean %EWL was 12.21 +/- 20.7 (range 67-75). Following conversion, mean BMI and %EWL at 12 months, respectively, were 31.6 +/- 4.2 kg/m2 and 55.2 +/- 24.7, at 24 months 33.6 +/- 5.6 kg/m2 and 45.3 +/- 20.1, and at 36 months 33.0 +/- 7.5 kg/m2 and 46.0 +/- 18.2. Conclusions: There is an increasing need for proven corrective solutions to failed LAGB. Our results show that con!
EMBASE:71046427
ISSN: 0930-2794
CID: 349002