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Undiagnosed ventricular septal defect with resultant Eisenmenger syndrome presenting with diplopia [Case Report]

Duncan, Ellen; Small, Adam; Sulica, Roxana; Halpern, Dan
Ventricular septal defect (VSD) is the most common congenital heart lesion among children. In most cases, however, it is identified and corrected in childhood, before long-term sequelae such as pulmonary hypertension develop. In this case report, we present a young man with an undiagnosed VSD with consequent Eisenmenger syndrome who initially presented to medical attention with diplopia found to be caused by cerebral infarcts.
PMID: 36456362
ISSN: 1532-8171
CID: 5374132

Multimodality Imaging of Caval and Coronary Sinus Venous Anomalies [Case Report]

Liebman, Jordan; Bamira, Daniel; Ro, Richard; Vainrib, Alan F; Small, Adam J; Donnino, Robert; Saric, Muhamed
PMCID:9556923
PMID: 36247374
ISSN: 2468-6441
CID: 5356652

Delivery Timing and Associated Outcomes in Pregnancies With Maternal Congenital Heart Disease at Term

Mok, Thalia; Woods, Allison; Small, Adam; Canobbio, Mary M; Tandel, Megha D; Kwan, Lorna; Lluri, Gentian; Reardon, Leigh; Aboulhosn, Jamil; Lin, Jeannette; Afshar, Yalda
Background Current recommendations for delivery timing of pregnant persons with congenital heart disease (CHD) are based on expert opinion. Justification for early-term birth is based on the theoretical concern of increased cardiovascular stress. The objective was to evaluate whether early-term birth with maternal CHD is associated with lower adverse maternal or neonatal outcomes. Methods and Results This is a retrospective cohort study of pregnant persons with CHD who delivered a singleton after 37 0/7 weeks gestation at a quaternary care center with a multidisciplinary cardio-obstetrics care team between 2013 and 2021. Patients were categorized as early-term (37 0/7 to 38 6/7 weeks) or full-term (≥39 0/7) births and compared. Multivariable logistic regression was conducted to calculate the adjusted odds ratio for the primary outcomes. The primary outcomes were composite adverse cardiovascular, maternal obstetric, and adverse neonatal outcome. Of 110 pregnancies delivering at term, 55 delivered early-term and 55 delivered full-term. Development of adverse cardiovascular and maternal obstetric outcome was not significantly different by delivery timing. The rate of composite adverse neonatal outcomes was significantly higher in early-term births (36% versus 5%, P<0.01). After adjusting for confounding variables, early-term birth remained associated with a significantly increased risk of adverse neonatal outcomes (adjusted odds ratio 11.55 [95% CI, 2.59-51.58]). Conclusions Early-term birth for pregnancies with maternal CHD was associated with an increased risk of adverse neonatal outcomes, without an accompanying decreased rate in adverse cardiovascular or obstetric outcomes. In the absence of maternal or fetal indications for early birth, induction of labor before 39 weeks for pregnancies with maternal CHD should be reserved for routine obstetrical indications.
PMID: 35943056
ISSN: 2047-9980
CID: 5286822

Multivalvular Endocarditis With Abscess: A Wild Goose Chase

Abuso, Stephanie; Rubin, Lily; Geraghty, Brian; Hoque, Tasneem; Better, Donna; Kumar, T K Susheel; Small, Adam; Halpern, Dan; Weisenberg, Scott; Fiorito, Theresa M
We report a case of Streptococcus mutans multivalvular infective endocarditis complicated by aortic root abscess and septic emboli in a 19-year-old male with a bicuspid aortic valve. This case illustrates the progression of untreated subacute bacterial endocarditis and highlights the importance of ongoing clinical suspicion for infective endocarditis in patients with underlying valvular defects.
PMID: 35389950
ISSN: 1532-0987
CID: 5205002

Isolated Anomalous Right Superior Pulmonary Venous Return to the Inferior Vena Cava [Case Report]

Tinsay, Maria Andrea Francesca M; Halpern, Dan G; Small, Adam J
Partial anomalous pulmonary venous connection is a rare congenital abnormality. We present images from an atypical case of isolated anomalous right superior pulmonary venous return to the inferior vena cava without other cardiac abnormalities.
PMID: 35757945
ISSN: 2150-136x
CID: 5278682

Emotions, Perceptions and Health Behaviors of Adult Congenital Heart Disease Patients during COVID-19 in New York City

Feinberg, Jodi L.; Sheng, Peter; Pena, Stephanie; Small, Adam J.; Wendelboe, Susanna; Nemani, Katlyn; Agrawal, Vikram; Halpern, Dan G.
Background: Adults with congenital heart disease (ACHD) have increased prevalence of mood and anxiety dis-orders. There are limited data regarding the influence of the COVID-19 pandemic on the mental health and health behaviors of these patients. Objective: The purpose is to evaluate the perceptions, emotions, and health behaviors of ACHD patients during the COVID-19 pandemic. Methods: In this cross-sectional study of ACHD patients, we administered surveys evaluating self-reported emotions, perceptions and health behaviors. Logistic regressions were performed to determine the adjusted odds of displaying each perception, emotion and health behavior based on predictor variables. Results: Ninety-seven patients (mean age 38.3 years, 46.4% female, 85.6% moderate or complex lesion) completed the survey. The majority of patients reported feeling moderately or very sad (63.1%), and 48.4% of patients identified themselves as feeling moderately or very anxious. The majority of patients perceived their risk of COVID-19 as moderate or high. Females were more likely to report feeling sad and anxious (95% CI 1.06"“10.96, p-value 0.039, and 95% CI 1.44"“15.30, p-value = 0.012, respectively), and were associated with higher odds of having a perceived increased risk of COVID-19 (95% CI 1.33"“10.59, p-value 0.012). There was no association between ACHD anatomic or physiologic classification and perceptions, emotions and health behaviors. Conclusions: Females were more likely to report feeling sad, anxious and an increased risk of COVID-19 in comparison to males. These findings indicate the need for mental health support and promotion of health behaviors during the pandemic amongst all ACHD patients, regardless of underlying condition.
SCOPUS:85137421722
ISSN: 1747-079x
CID: 5330302

Short-Segment Type B Interrupted Aortic Arch Presenting With Subarachnoid Hemorrhage With Subsequent Primary Percutaneous Repair

Ramachandran, Abhinay; Argilla, Michael; Saharan, Sunil; Halpern, Dan; Small, Adam
This report describes a young adult man presenting with subarachnoid hemorrhage secondary to an intracranial aneurysm who was found to have a short-segment type B interrupted aortic arch. We describe the clinical presentation, evaluation, and management of this patient and highlight imaging findings and percutaneous repair of the aneurysm and interrupted aortic arch. (Level of Difficulty: Intermediate.).
PMCID:8543161
PMID: 34729511
ISSN: 2666-0849
CID: 5038122

Acquired pulmonary vein stenosis resulting in haemoptysis: a case series [Case Report]

Talmor, Nina; Massera, Daniele; Small, Adam; Ramachandran, Abhinay; Argilla, Michael; Staniloae, Cezar S; Latson, Larry A; Halpern, Dan G
Background/UNASSIGNED:Acquired pulmonary vein stenosis (PVS) is an infrequent complication of atrial fibrillation ablation that is often misdiagnosed due to predominant respiratory symptoms. It can result in pulmonary venous hypertension, with varying presentations, ranging from shortness of breath to haemoptysis. Case summary/UNASSIGNED:We report two patients with a history of paroxysmal atrial fibrillation treated with radiofrequency ablation and pulmonary vein (PV) isolation, who subsequently developed PVS. Case 1 initially presented with indolent symptoms of shortness of breath and cough. He was initially diagnosed with and treated for pneumonia. In contrast, Case 2 presented with massive haemoptysis, requiring intubation and intensive care unit admission. Both patients were eventually diagnosed with PVS by computed tomography. They were treated with PV angioplasty and stenting. Discussion/UNASSIGNED:While previously limited to the congenital heart disease population, PVS is occurring more frequently now in adult patients as a complication of ablation procedures. It is most effectively treated with angioplasty and stent implantation but has a high rate of recurrence.
PMCID:8243221
PMID: 34222784
ISSN: 2514-2119
CID: 4932892

Peripheral venous pressure accurately predicts central venous pressure in the adult Fontan circulation

Tan, Weiyi; Small, Adam; Gallotti, Roberto; Moore, Jeremy; Aboulhosn, Jamil
BACKGROUND:Patients with the Fontan circulation lack a subpulmonary ventricular pump and thus the main driver for pulmonary blood flow is a high central venous pressure. Peripheral venous pressure (PVP) measurement has been shown to be a reproducible and fairly accurate surrogate for central venous pressure (CVP), but not specifically for the adult Fontan circulation. This study aims to determine the relationship of PVP to CVP in adult Fontan patients. METHODS:All adult patients (≥18 yo) with a Fontan circulation undergoing cardiac catheterization were included. Both CVP and PVP were measured during the catheterization. The relationship between the peripheral venous and central venous pressures was assessed using simple linear regression and the Bland-Altman plot analysis for differences. RESULTS:value of 0.83 (p < 0.001). The CVP can be estimated with PVP measurements using the formula CVP = (0.86 * PVP) + 1.3. A Bland-Altman plot for PVP and CVP demonstrated that the PVP overestimated CVP by a mean of 1.2 mmHg, with a 95% limit of agreement of -5.2 mmHg to 2.8 mmHg. CONCLUSIONS:In adult Fontan patients, measuring PVP is a reliable, less-invasive, and accurate method of estimating the CVP during cardiac catheterization procedures. These findings may enable outpatient monitoring of Fontan hemodynamics.
PMID: 33189798
ISSN: 1874-1754
CID: 4734632

High-Output Heart Failure From Growth of Vascular Malformations in Multiple Gestation Pregnancy [Case Report]

Srivastava, Pratyaksh K; Vyas, Nina; Jones, Jesse; Wong, Thalia C; Holliman, Kerry; Small, Adam J; Rao, Rashmi R; Dowling, Erin P; Finn, J Paul; Duckwiler, Gary R; Reardon, Leigh C; Aboulhosn, Jamil A; Ascher, Simon B; Hogeling, Marcia; Lluri, Gentian; Yang, Eric H
PMID: 31658832
ISSN: 1941-3297
CID: 4502212