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Adverse Pregnancy Outcomes in Sjogren's Disease Compared to Controls: An Interdisciplinary Approach with Maternal-Fetal Medicine

Tesoriero, Lauren; Kidd, Jennifer; Piccione, Julie; Izmirly, Peter; Akerman, Meredith; Carsons, Steven; Rekawek, Patricia; Nusbaum, Julie
OBJECTIVES/UNASSIGNED:Outside of the association of SS-A antibody with congenital heart block, little is known about adverse maternal and neonatal outcomes, in patients with Sjogren's disease (SjD). Our study involved collaboration with maternal-fetal medicine (MFM). METHODS/UNASSIGNED:-test and Fisher's exact test. RESULTS/UNASSIGNED:48 patients were included: 12 SjD patients and 36 controls. APO was significantly increased in SjD with one preterm birth, one fetal growth restriction, and one limb anomaly; non-SjD had one cardiac anomaly. There were no cases of CHB. SjD patients were more likely to be delivered by cesarean delivery. CONCLUSION/UNASSIGNED:There was an increased risk of APO in SjD patients compared with controls. No significant difference in neonatal outcomes was found. We speculate that placental pathology may play a role in pathophysiology and future studies should be performed. KEY POINTS/UNASSIGNED:There was an increased risk of APO in SjD patients compared with controls.No significant difference in neonatal outcomes was found.We speculate that placental pathology may play a role in pathophysiology, prompting future studies.
PMCID:12020534
PMID: 40291586
ISSN: 2157-6998
CID: 5833052

Determining the Efficacy of Various Governmental Interventions in Stemming the Spread of SARS-CoV-2 in Seven Locations

Mendelson, Jordan; Moawad, Andrew; Tesoriero, Lauren; Wilkenfeld, Marc
PMCID:9134871
PMID: 35646769
ISSN: 2296-2565
CID: 5236052

Diplopia: A Rare Manifestation of Neuroborreliosis [Case Report]

Dixit, Ayushi; Garcia, Yesika; Tesoriero, Lauren; Berman, Charles; Rizzo, Vincent
Early disseminated Lyme disease typically presents with cardiac, rheumatologic, or neurologic symptoms. Though uncommon, Borrelia burgdorferi can invade the central nervous system and cause neuroborreliosis. In these patients, facial palsy, headache, and stiffness of the neck are the most common presenting symptoms. Our case describes a patient with oculomotor nerve palsy manifesting as double vision as the initial presentation of neuroborreliosis.
PMCID:6076924
PMID: 30105109
ISSN: 2090-6668
CID: 5087142