Faculty Bibliography

22 patients infected with fluoroquinolone-resistant Mycobacterium tuberculosis in New York City were identified between January, 1991, and November, 1993. In 16 patients resistance arose as a result of inadequate or inappropriate treatment. 6 patients had primary infection with fluoroquinolone-resistant organisms; 5 acquired the organisms nosocomially. Seven distinct patterns of restriction-fragment length polymorphism were identified in isolates from 21 patients. Fluoroquinolones should be restricted to patients with multidrug-resistant disease or intolerance to other antituberculosis drugs. All patients with multidrug-resistant tuberculosis should be on directly observed therapy

Whiplash, a common neck injury that affects 120,000 Americans a year, usually after automobile accidents, is little understood and often ineffectively treated, a new study has found. An international team of experts who reviewed more than 10,000 scientific articles published in the past 15 years found little evidence to justify most existing therapies, and also found that most are prescribed by doctors who are poorly trained in caring for whiplash patients. Moreover, there is no generally accepted uniform approach for the management of whiplash, the authors said in a scathing report published in the journal Spine and discussed this week at a news conference in Montreal. The authors said they believed it was the most comprehensive study of whiplash ever done

An international team of experts who reviewed more than 10,000 scientific articles published in the last 15 years found little scientifically rigorous evidence to justify most existing therapies, and also found that most are prescribed by doctors who are poorly trained in caring for whiplash patients. Moreover, there is no generally accepted uniform approach for the management of whiplash, the authors said in a scathing report published in the journal Spine and discussed yesterday at a news conference in Montreal. The authors said they believed it was the most comprehensive study of whiplash ever done. Whiplash often results when the impact of an accident suddenly thrusts the victim's head backward and then forward, injuring the muscles and soft tissue in the neck and upper spine to produce neck pain and limit motion of the neck. Whiplash may result from rear-end or side-impact motor vehicle collisions, but it also can occur during diving and other mishaps

Whiplash, a common neck injury that affects 120,000 Americans a year, usually after automobile accidents, is little understood and often ineffectively treated, a new study has found. An international team of experts who reviewed more than 10,000 scientific articles published in the last 15 years found little scientifically rigorous evidence to justify most existing therapies, and also found that most are prescribed by doctors who are poorly trained in caring for whiplash patients. Whiplash often results when the impact of an accident suddenly thrusts the victim's head backward and then forward, injuring the muscles and soft tissue in the neck and upper spine to produce neck pain and limit motion of the neck. Whiplash may result from rear-end or side-impact motor vehicle collisions, but it can also occur during diving and other mishaps

An international team of experts has found little scientifically rigorous evidence to justify most existing whiplash therapies. The experts conclude that standard therapies are often ineffective, and sometimes may even be harmful, and that there is no generally accepted uniform approach for the management of whiplash

International experts who reviewed more than 10,000 scientific articles published in the last 15 years found little scientifically rigorous evidence to justify most existing therapies. They also found that most are prescribed by doctors who are poorly trained in caring for whiplash patients. Standard therapies are often ineffective, and sometimes may even be harmful, the study's authors said. Moreover, there is no generally accepted uniform approach for the management of whiplash, the authors said in a scathing report published in the journal Spine and discussed Monday at a press conference in Montreal. The authors said they believed it was the most comprehensive study of whiplash ever done. Whiplash often results when the impact of an accident suddenly thrusts the victim's head backward and then forward, injuring the muscles and soft tissue in the neck and upper spine to produce neck pain and limit motion of the neck. Whiplash may result from rear-end or side-impact motor vehicle collisions, but it can also occur during diving and other mishaps

Whiplash is a little understood neck injury and often ineffectively treated, a Quebec study has found. An international team of experts who reviewed more than 10,000 scientific articles found little scientifically rigorous evidence to justify most existing therapies and said most are prescribed by doctors poorly trained in caring for whiplash patients. Standard therapies are often ineffective and sometimes may even be harmful, the authors of the study said. Even the few therapies tested in a scientific manner, such as soft collars, muscle relaxants and other drugs, seem to be ineffective

Whiplash, a common neck injury that affects 120,000 Americans a year, usually after automobile accidents, is little understood and often ineffectively treated, a new study has found. An international team of experts who reviewed more than 10,000 scientific articles published in the past 15 years found little scientifically rigorous evidence to justify most existing therapies, and also found that most are prescribed by doctors poorly trained in caring for whiplash patients. Whiplash often results when the impact of an accident suddenly thrusts the victim's head backward and then forward, injuring the muscles and soft tissue in the neck and upper spine to produce neck pain and limit motion of the neck. Whiplash may result from rear-end or side-impact motor vehicle collisions, but it also can occur during diving and other mishaps

The current tuberculosis epidemic in the United States is marked, in many areas, by high rates of noncompliance with antituberculous regimens. In response to this, a comprehensive program of medical, nursing, social services, and supervised therapy was developed at Bellevue Hospital. Most patients were referred to the on-site directly observed therapy program (DOT) located in the hospital. Patients on DOT received daily or twice weekly therapy, and were given incentives to enhance compliance. Outreach was used to track patients who missed appointments. From November 1992 through July 1993, 113 patients were referred. HIV infection, homelessness, illicit drug use, and alcoholism were common. Follow-up revealed that 11 patients were noncompliant and completely lost to follow-up; of the remaining 102, 99% achieved bacteriologic cure. Of the 102 patients who received therapy, 74 attended the Bellevue DOT clinic, 16 attended other DOT programs in the city or received medication at home, and three died of HIV-related, nontuberculous illness. Nine patients were self-medicated and judged treatment successes. We conclude that a comprehensive hospital-based tuberculosis control program is capable of achieving a high degree of success, even in a population at high risk for noncompliance

The standard approach to treating obesity, which affects 20-30% of all Americans, does not work, and physicians need to develop new ways to help obese people. Treatment beyond behavior modification is needed as there appears to be a very real physiological basis for obesity