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department:Medicine. General Internal Medicine

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Learning the language of health equity [Editorial]

Squires, Allison; Thompson, Roy
PMID: 34661911
ISSN: 1098-240x
CID: 5037242

Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID-19 pandemic

Nguyen, Thanh N; Haussen, Diogo C; Qureshi, Muhammad M; Yamagami, Hiroshi; Fujinaka, Toshiyuki; Mansour, Ossama Y; Abdalkader, Mohamad; Frankel, Michael; Qiu, Zhongming; Taylor, Allan; Lylyk, Pedro; Eker, Omer F; Mechtouff, Laura; Piotin, Michel; Lima, Fabricio Oliveira; Mont'Alverne, Francisco; Izzath, Wazim; Sakai, Nobuyuki; Mohammaden, Mahmoud; Al-Bayati, Alhamza R; Renieri, Leonardo; Mangiafico, Salvatore; Ozretic, David; Chalumeau, Vanessa; Ahmad, Saima; Rashid, Umair; Hussain, Syed Irteza; John, Seby; Griffin, Emma; Thornton, John; Fiorot, Jose Antonio; Rivera, Rodrigo; Hammami, Nadia; Cervantes-Arslanian, Anna M; Dasenbrock, Hormuzdiyar H; Vu, Huynh Le; Nguyen, Viet Quy; Hetts, Steven; Bourcier, Romain; Guile, Romain; Walker, Melanie; Sharma, Malveeka; Frei, Don; Jabbour, Pascal; Herial, Nabeel; Al-Mufti, Fawaz; Ozdemir, Atilla Ozcan; Aykac, Ozlem; Gandhi, Dheeraj; Chugh, Chandril; Matouk, Charles; Lavoie, Pascale; Edgell, Randall; Beer-Furlan, Andre; Chen, Michael; Killer-Oberpfalzer, Monika; Pereira, Vitor Mendes; Nicholson, Patrick; Huded, Vikram; Ohara, Nobuyuki; Watanabe, Daisuke; Shin, Dong Hun; Magalhaes, Pedro Sc; Kikano, Raghid; Ortega-Gutierrez, Santiago; Farooqui, Mudassir; Abou-Hamden, Amal; Amano, Tatsuo; Yamamoto, Ryoo; Weeks, Adrienne; Cora, Elena A; Sivan-Hoffmann, Rotem; Crosa, Roberto; Möhlenbruch, Markus; Nagel, Simon; Al-Jehani, Hosam; Sheth, Sunil A; Lopez Rivera, Victor S; Siegler, James E; Sani, Achmad Fidaus; Puri, Ajit S; Kuhn, Anna Luisa; Bernava, Gianmarco; Machi, Paolo; Abud, Daniel G; Pontes-Neto, Octavio M; Wakhloo, Ajay K; Voetsch, Barbara; Raz, Eytan; Yaghi, Shadi; Mehta, Brijesh P; Kimura, Naoto; Murakami, Mamoru; Lee, Jin Soo; Hong, Ji Man; Fahed, Robert; Walker, Gregory; Hagashi, Eiji; Cordina, Steve M; Roh, Hong Gee; Wong, Ken; Arenillas, Juan F; Martinez-Galdamez, Mario; Blasco, Jordi; Rodriguez Vasquez, Alejandro; Fonseca, Luisa; Silva, M Luis; Wu, Teddy Y; John, Simon; Brehm, Alex; Psychogios, Marios; Mack, William J; Tenser, Matthew; Todaka, Tatemi; Fujimura, Miki; Novakovic, Roberta; Deguchi, Jun; Sugiura, Yuri; Tokimura, Hiroshi; Khatri, Rakesh; Kelly, Michael; Peeling, Lissa; Murayama, Yuichi; Winters, Hugh Stephen; Wong, Johnny; Teleb, Mohamed; Payne, Jeremy; Fukuda, Hiroki; Miyake, Kosuke; Shimbo, Junsuke; Sugimura, Yusuke; Uno, Masaaki; Takenobu, Yohei; Matsumaru, Yuji; Yamada, Satoshi; Kono, Ryuhei; Kanamaru, Takuya; Morimoto, Masafumi; Iida, Junichi; Saini, Vasu; Yavagal, Dileep; Bushnaq, Saif; Huang, Wenguo; Linfante, Italo; Kirmani, Jawad; Liebeskind, David S; Szeder, Viktor; Shah, Ruchir; Devlin, Thomas G; Birnbaum, Lee; Luo, Jun; Churojana, Anchalee; Masoud, Hesham E; Lopez, Carlos Ynigo; Steinfort, Brendan; Ma, Alice; Hassan, Ameer E; Al Hashmi, Amal; McDermott, Mollie; Mokin, Maxim; Chebl, Alex; Kargiotis, Odysseas; Tsivgoulis, Georgios; Morris, Jane G; Eskey, Clifford J; Thon, Jesse; Rebello, Leticia; Altschul, Dorothea; Cornett, Oriana; Singh, Varsha; Pandian, Jeyaraj; Kulkarni, Anirudh; Lavados, Pablo M; Olavarria, Veronica V; Todo, Kenichi; Yamamoto, Yuki; Silva, Gisele Sampaio; Geyik, Serdar; Johann, Jasmine; Multani, Sumeet; Kaliaev, Artem; Sonoda, Kazutaka; Hashimoto, Hiroyuki; Alhazzani, Adel; Chung, David Y; Mayer, Stephan A; Fifi, Johanna T; Hill, Michael D; Zhang, Hao; Yuan, Zhengzhou; Shang, Xianjin; Castonguay, Alicia C; Gupta, Rishi; Jovin, Tudor G; Raymond, Jean; Zaidat, Osama O; Nogueira, Raul G
BACKGROUND:During the COVID-19 pandemic, decreased volumes of stroke admissions and mechanical thrombectomy were reported. The study's objective was to examine whether subarachnoid haemorrhage (SAH) hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines. METHODS:We conducted a cross-sectional, retrospective, observational study across 6 continents, 37 countries and 140 comprehensive stroke centres. Patients with the diagnosis of SAH, aneurysmal SAH, ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases, 10th Revision, codes. The 3-month cumulative volume, monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before (1 year and immediately before) and during the pandemic, defined as 1 March-31 May 2020. The prior 1-year control period (1 March-31 May 2019) was obtained to account for seasonal variation. FINDINGS/RESULTS:There was a significant decline in SAH hospitalisations, with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic, representing a relative decline of 22.5% (95% CI -24.3% to -20.7%, p<0.0001). Embolisation of ruptured aneurysms declined with 1170-1035 procedures, respectively, representing an 11.5% (95%CI -13.5% to -9.8%, p=0.002) relative drop. Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations, a 24.9% relative decline (95% CI -28.0% to -22.1%, p<0.0001). A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1% (95% CI 32.3% to 50.6%, p=0.008) despite a decrease in SAH admissions in this tertile. INTERPRETATION/CONCLUSIONS:There was a relative decrease in the volume of SAH hospitalisations, aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic. These findings in SAH are consistent with a decrease in other emergencies, such as stroke and myocardial infarction.
PMCID:8006491
PMID: 33771936
ISSN: 2059-8696
CID: 4830292

On Recommending Specific Lung Ultrasound Protocols in the Assessment of Medical Inpatients with Known or Suspected Coronavirus Disease-19 Reply [Letter]

Ma, Irene W Y; Noble, Vicki E; Mints, Gregory; Wong, Tanping; Tonelli, Ana Claudia; Hussain, Arif; Liu, Rachel B; Hergott, Christopher A; Dumoulin, Elaine; Chee, Alex; Miller, Daniel J; Walker, Brandie; Buchanan, Brian; Wagner, Michael; Arishenkoff, Shane; Liteplo, Andrew S
PMID: 33555607
ISSN: 1550-9613
CID: 4779362

Adherence to levetiracetam for management of epilepsy: Assessment with electronic monitors

Kolli, Sree S; Snyder, Stephanie N; Cardwell, Leah A; Cline, Abigail E; Unrue, Emily L; Feldman, Steven R; O Donovan, Cormac A
INTRODUCTION/BACKGROUND:Anti-seizure medications are used to manage epilepsy and require long-term adherence to maintain therapeutic drug levels. We assessed adherence to levetiracetam and the use of a digital intervention to improve adherence in patients with epilepsy. METHODS:30 participants with epilepsy were randomized 1:1 either to a digital email adherence intervention or control group. All patients were provided levetiracetam equipped with electronic monitoring caps to assess patient adherence to medication. Patients were followed for 6 months, with return visits at 1 month, 3 months, and 6 months. RESULTS:Subjects randomized to the control arm (n = 15) took 66% of the prescribed doses compared to the intervention group, who took 65% of prescribed doses (n = 15). Nine participants did not complete the study. Of the twenty-one participants that completed the study, the overall rate of adherence was 72% of prescribed doses taken. Two subjects in the control group and three subjects in the intervention group were adherent every month of the study-taking at least 80% of prescribed doses. Those randomized to the control group took the correct number of doses 44% of days in the study, and those in the intervention group took the correct number of doses 37% of days. DISCUSSION/CONCLUSIONS:Poor adherence to levetiracetam is common. An internet-based email survey intervention did not improve adherence to levetiracetam in epilepsy patients. Further advances in adherence are needed to help patients receive the maximum benefit of their medical treatments.
PMID: 34687986
ISSN: 1532-2688
CID: 5505672

Assessing learner engagement with virtual educational events: Development of the Virtual In-Class Engagement Measure (VIEM)

Dickinson, K J; Caldwell, K E; Graviss, E A; Nguyen, D T; Awad, M M; Tan, S; Winer, J H; Pei, K Y; ,
BACKGROUND:The COVID-19 pandemic has necessitated virtual education, but effects on learner engagement are unknown. We developed a virtual in-class engagement measure (VIEM) to assess learner engagement in online surgical education events. METHODS:Using the STROBE, an observer collected tool to document student engagement, as a template an ASE committee workgroup developed the VIEM. The VIEM had two parts: observer assessment and learner self-assessment of engagement. Trained observers collected engagement data from two institutions using the VIEM. Surgical attendings, fellows and residents were observed during virtual learning events. Educator attitudes towards online teaching were also assessed via survey. RESULTS:22 events with 839 learners were observed. VIEM distinguished between sessions with low and high engagement. 20% of learners pretended to participate. Half of instructors were comfortable with virtual teaching, but only 1/3 believed was as effective as in-person. 2/3 of teachers believed video learners were more engaged than audio learners. CONCLUSIONS:Virtual platforms do not automatically translate into increased engagement. Standard tools such as VIEM may help with assessment of engagement during virtual education.
PMID: 34602277
ISSN: 1879-1883
CID: 5772282

Does a measure of Medical Professional Identity Formation predict communication skills performance?

Kalet, Adina; Ark, Tavinder K; Monson, Verna; Song, Hyuksoon S; Buckvar-Keltz, Lynn; Harnik, Victoria; Yingling, Sandra; Rivera, Rafael; Tewksbury, Linda; Lusk, Penelope; Crowe, Ruth
OBJECTIVE:To validate an approach to measuring professional identity formation (PIF), we explore if the Professional Identity Essay (PIE), a stage score measure of medical professional identity (PI), predicts clinical communication skills. METHODS:Students completed the PIE during medical school orientation and a 3-case Objective Structured Clinical Exam (OSCE) where standardized patients reliably assessed communication skills in 5 domains. Using mediation analyses, relationships between PIE stage scores and communication skills were explored. RESULTS:For the 351 (89%) consenting students, controlling for individual characteristics, there were increases in patient counseling (6.5%, p<0.01), information gathering (4.3%, p = 0.01), organization and management (4.1%, p = 0.02), patient assessment (3.6%, p = 0.04), and relationship development (3.5%, p = 0.03) skills for every half stage increase in PIE score. The communication skills of lower socio-economic status (SES) students are indirectly impacted by their slightly higher PIE stage scores. CONCLUSION/CONCLUSIONS:Higher PIE stage scores are associated with higher communication skills and lower SES. PRACTICE IMPLICATIONS/CONCLUSIONS:PIE predicts critical clinical skills and identifies how SES and other characteristics indirectly impact future clinical performance, providing validity evidence for using PIE as a tool in longitudinal formative academic coaching, program and curriculum evaluation, and research.
PMID: 33896685
ISSN: 1873-5134
CID: 4889222

HIV Diagnosis and the Clinical Course of COVID-19 Among Patients Seeking Care Within the New York City Public Hospital System During the Initial Pandemic Peak

Kaplan-Lewis, Emma; Banga, Jaspreet; Khan, Maria; Casey, Eunice; Mazumdar, Medha; Bratu, Simona; Abdallah, Marie; Pitts, Robert; Leider, Jason; Hennessey, Karen; Cohen, Gabriel M; Cleland, Charles M; Salama, Carlos
Reports conflict on how HIV infection influences the clinical course of COVID-19. The New York City (NYC) public hospital system provides care for over 14,000 people with HIV, was central in responding to the COVID-19 pandemic, and is therefore in a unique position to evaluate the intersection of these concurrent infections. Retrospective chart review of patients presenting to NYC Health and Hospitals (NYC H+H) diagnosed with COVID-19 infection from March 1, 2020, through April 28, 2020, compared people living with HIV (PLWH) and a propensity-matched (PM) control group of patients without HIV to evaluate associations between HIV status and COVID-19 outcomes. Two hundred thirty-four PLWH presented for COVID-19 testing and 110 (47%) were diagnosed with COVID-19. Among 17,413 patients with COVID-19 and without HIV, 1:n nearest neighbor propensity score matching identified 194 patients matched on age, sex, race, and any comorbidity. In the sample with COVID-19 (N = 304), PLWH (9.1%) had lower rates of mortality than controls [19.1%; PM odds ratio (PM-OR): 0.41, 95% confidence interval (CI): 0.19-0.86]. Among hospitalized COVID-19 patients (N = 179), HIV infection was associated with lower rates of mechanical ventilation (PM-OR: 0.31, 95% CI: 0.11-0.84) and mortality (PM-OR: 0.40, 95% CI: 0. 17-0.95). In the extended pandemic period through April 2021, aggregate data by HIV status suggested elevated hospitalization and mortality rates in PLWH versus people without HIV. These results suggest that the direct biological impacts of the HIV virus do not negatively influence COVID-19-related outcomes when controlling for comorbidity and demographic variables.
PMID: 34780305
ISSN: 1557-7449
CID: 5046482

Review of the Medical Student Performance Evaluation: analysis of the end-users' perspective across the specialties

Bird, Jeffrey B; Friedman, Karen A; Arayssi, Thurayya; Olvet, Doreen M; Conigliaro, Rosemarie L; Brenner, Judith M
The Medical Student Performance Evaluation (MSPE) is an important tool of communication used by program directors to make decisions in the residency application process. To understand the perspective and usage of the MSPE across multiple medical specialties now and in anticipation of the planned changes in USMLE Step 1 score-reporting. A survey instrument including quantitative and qualitative measures was developed and piloted. The final survey was distributed to residency programs across 28 specialties in 2020 via the main contact on the ACGME listserv. Of the 28 specialties surveyed, at least one response was received from 26 (93%). Eight percent of all programs (364/4675) responded to the survey, with most respondents being program directors. Usage of the MSPE varied among specialties. Approximately 1/3 of end-users stated that the MSPE is very or extremely influential in their initial screening process. Slightly less than half agreed or strongly agreed that they trust the information to be an accurate representation of applicants, though slightly more than half agree that the MSPE will become more influential once USMLE Step 1 becomes pass/fail. Professionalism was rated as the most important component and noteworthy characteristics among the least important in the decision-making process. Performance in the internal medicine clerkship was rated as the most influential while neurology and psychiatry performances were rated as less influential. Overwhelmingly, respondents suggested that including comparative performance and/or class rank would make the MSPE more useful once USMLE Step 1 becomes pass/fail. MSPE end-users across a variety of specialties utilize this complex document in different ways and value it differentially in their decision-making processes. Despite this, continued mistrust of the MSPE persists. A better understanding of end-users' perceptions of the MSPE offers the UME community an opportunity to transform the MSPE into a highly valued, trusted document of communication.
PMCID:7899642
PMID: 33606615
ISSN: 1087-2981
CID: 4823282

Kairos care in a Chronos world: Midwifery care as model of resistance and accountability in public health settings

Niles, Paulomi Mimi; Vedam, Saraswathi; Witkoski Stimpfel, Amy; Squires, Allison
BACKGROUND:In the Unites States (US), pregnancy-related mortality is 2-4 times higher for black and indigenous women irrespective of income and education. The integration of midwifery as a fundamental component of standard maternity services has been shown to improve health outcomes and service user satisfaction, including among underserved and minoritized groups. Nonetheless, there remains limited uptake of this model in the United States. In this study, we examine a series of interdependent factors that shape how midwifery care operates in historically disenfranchised communities within the Unites States. METHODS:Using data collected from in-depth, semi-structured interviews, the purpose of this study was to examine the ways midwives recount, describe, and understand the relationships that drive their work in a publicly funded urban health care setting serving minoritized communities. Using a qualitative exploratory research design, guided by critical feminist theory, twenty full-scope midwives working in a large public health care network participated. Data were thematically analyzed using Braun & Clarke's inductive thematic analysis to interpret data and inductively identify patterns in participants' experiences. FINDINGS/RESULTS:The overarching theme "Kairos care in a Chronos World" captures the process of providing health-promoting, individualized care in a system that centers measurement, efficiency, and pathology. Five subthemes support the central theme: (1) the politics of progress, (2) normalizing pathologies, (3) cherished connections, (4) protecting the experience, and (5) caring for the social body. Midwives used relationships to sustain their unique care model, despite the conflicting demands of dominant (and dominating) medical models. CONCLUSION/CONCLUSIONS:This study offers important insight into how midwives use a Kairos approach to maternity care to enhance quality and safety. In order to realize equitable access to optimal outcomes, health systems seeking to provide robust services to historically disenfranchised communities should consider integration of relationship-based strategies, including midwifery care.
PMID: 34137073
ISSN: 1523-536x
CID: 4929512

How Clinicians Manage Routinely Low Supplies of Personal Protective Equipment

Ridge, Laura Jean; Stimpfel, Amy Witkoski; Dickson, Victoria Vaughan; Klar, Robin Toft; Squires, Allison Patricia
BACKGROUND:Recommended personal protective equipment (PPE) is routinely limited or unavailable in low-income countries, but there is limited research as to how clinicians adapt to that scarcity, despite its implications for patients and workers. METHODS:This is a qualitative secondary analysis of case study data collected in Liberia in 2019. Data from the parent study were included in this analysis if it addressed availability and use of PPE in the clinical setting. Conventional content analysis was used on data including: field notes documenting nurse practice, semi-structured interview transcripts, and photographs. FINDINGS/RESULTS:Data from the majority of participants (32/37) and all facilities (12/12) in the parent studies were included. 83% of facilities reported limited PPE. Five management strategies for coping with limited PPE supplies were observed, reported, or both: rationing PPE, self-purchasing PPE, asking patients to purchase PPE, substituting PPE, and working without PPE. Approaches to rationing PPE included using PPE only for symptomatic patients or not performing physical exams. Substitutions for PPE were based on supply availability. CONCLUSIONS:Strategies developed by clinicians to manage low PPE likely have negative consequences for both workers and patients; further research into the topic is important, as is better PPE provision in low-income countries.
PMID: 34416315
ISSN: 1527-3296
CID: 4968912