Faculty Bibliography

The safety and immunogenicity of an inactivated hepatitis A vaccine (HM175) were evaluated in 151 seronegative health professionals (age range, 21-65 years; mean, 30). A 720-ELISA unit dose was administered to 78 vaccinees at 0, 1, and 6 months and to 73 vaccinees at 0, 1, and 12 months. Seroconversion rates were 90% in both groups 1 month after the first inoculation and 99% and 100%, respectively, 1 month after the second inoculation. Geometric mean antibody titers (GMTs) 1 month after the third inoculation were highest in the group vaccinated at 0, 1, and 12 months. GMTs were higher in women than in men. The vaccine was well tolerated; the most frequent side effect was transient soreness at the site of inoculation. No serious adverse reactions were observed. Thus, HM175 inactivated hepatitis A vaccine is safe and highly immunogenic

Imagine such infinitely long odds - 1 in 85 million. That's about the magnitude of the risk of a National Football League player becoming infected with HIV, the virus that causes AIDS, through spillage of contaminated blood, a new study has found. Although it is not clear how this risk translates into competitive diving, the essential issue is the same in all the discussions about the disclosure from Greg Louganis, the 1984 and 1988 Olympic gold medal winner, that he was HIV-infected when he hit the board during a dive and spilled blood in the chlorinated pool. The potential risk of transmitting HIV and other microbes through blood during sports is extremely low, according to a review of the issue by federal officials of the Centers for Disease Control and Prevention in Atlanta

Italian public health officials who reviewed the available information could not definitively establish athletic activity as the source of the soccer player's H.I.V. infection. Nor could they exclude the possibility that the man, who worked in a drug dependency rehabilitation center, acquired the infection through nonathletic risks, the authors of the report wrote in the Feb. 15 issue of the Annals of Internal Medicine, a leading medical journal that is published by the American College of Physicians in Philadelphia. The health officials said hepatitis B, a virus that causes a potentially fatal liver infection, is more likely to be transmitted in sports than H.I.V. The reason for the difference is that hepatitis B virus is present in much higher concentrations in blood and lasts longer outside the body than does H.I.V. In their calculations, the researchers assumed that the risks of H.I.V. transmission were the same for a cut suffered in sports and a needle stick injury in a hospital or doctor's office. Studies indicate the risk of H.I.V. transmission is one in 300 needle stick injuries

Imagine such infinitely long odds -- 1 in 85 million. That's about the magnitude of the risk of a National Football League player becoming infected with HIV, the virus that causes AIDS, through spillage of contaminated blood, a new study has found. Although it is not clear how this risk translates into competitive diving, the essential issue is the same in all the discussions about the disclosure from Greg Louganis, the 1984 and 1988 Olympic gold medal winner, that he was HIV-infected when he hit the board during a dive and spilled blood in the chlorinated pool. The potential risk of transmitting HIV and other microbes through blood during sports is extremely low, according to a review of the issue by federal officials of the Centers for Disease Control and Prevention in Atlanta

Federal health officials on Feb 22, 1995 licensed the first vaccine in the US to prevent hepatitis A, a serious and common viral liver infection. The FDA said it gave SmithKline Beecham PLC approval to sell the vaccine, Havrix

Federal health officials Wednesday licensed the first vaccine in the United States to prevent hepatitis A, a serious and common viral liver infection that has plagued the Mid-South recently. The Food and Drug Administration said it gave SmithKline Beecham PLC approval to sell the vaccine. The company said it would begin distributing the vaccine, known as Havrix, in the next several weeks. Dr. Sherman Kahn, the Memphis and Shelby County Health Department's health officer, said the department is eager to learn more about the vaccine's availability and its recommended use. By Wednesday, 139 cases of hepatitis A had been reported locally in the most recent outbreak, including 28 requiring hospitalization

Hepatitis A can cause loss of appetite, fatigue, fever, muscle aches, nausea and vomiting, which are often followed one to two weeks later by a yellowing of the skin known as jaundice. The yellowing is a result of a buildup of bile pigments in the blood that follows the liver damage from the hepatitis. Many people suffer mild hepatitis A infections without jaundice

Summary: The procedure on the optic nerve to correct a sudden vision loss is possibly harmful, federal officials determine An eye operation routinely done to correct the most common cause of sudden loss of vision in people 60 and older has been found to be so ineffective, and possibly harmful, that federal health officials are warning eye surgeons to stop doing the procedure. The eye condition, known as non-arteritic ischemic optic neuropathy, comes on so suddenly that those affected by it often awake with their vision gone in one eye

An eye operation routinely done to correct the most common cause of sudden loss of vision in people 60 and older has been found to be so ineffective, and possibly harmful, that federal health officials are warning eye surgeons to stop doing the procedure. The eye condition, known as non-arteritic ischemic optic neuropathy, comes on so suddenly that those affected by it often awake with their vision gone in one eye. In 40 percent of those affected, loss of vision can eventually develop in both eyes. The condition results from a painless swelling of the optic nerve that connects the eye and the brain

An eye operation routinely done to correct the most common cause of sudden loss of vision in people 60 and older has been found to be so ineffective, and possibly harmful, that federal health officials are warning eye surgeons to stop doing the procedure. The eye condition, known as nonarteritic ischemic optic neuropathy, comes on so suddenly that those affected by it often awake with their vision gone in one eye. In 40 percent of those affected, loss of vision can eventually develop in both eyes. The condition results from a painless swelling of the optic nerve that connects the eye and the brain