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Influenza, or the flu, is a serious illness caused by a specific virus; flu symptoms tend to be extremely abrupt in onset and are accompanied by muscle aches, chills and a sore throat. Influenza is often treatable, and those who suspect they have the flu should call a doctor to see whether they will benefit from an antiviral medication called amantadine

The previous day, Quayle had not felt well and had gone to the hospital emergency room for a chest X-ray. The doctors diagnosed walking pneumonia, [Ann Hathaway] said. She said Quayle was sent home with a prescription for medication. He returned to the hospital Monday because of breathing difficulty. Doctors then determined Quayle had a blood clot in a lung, a condition known as a pulmonary embolus, which can be fatal if not treated quickly. An embolus is any substance that forms in one part of the body, breaks off and travels elsewhere in the body. Emboli begin as blood clots, usually forming in a vein in the leg or pelvis, before a piece breaks off and lodges in a lung. Doctors said they did not know why Quayle's clot developed

Although it can be difficult to distinguish pneumonia from a blood clot in the lung, doctors not connected with [Marilyn Quayle]'s case said the symptoms and medical history can be very helpful in coming to an accurate diagnosis. But the two paragraph long news release did not say whether Quayle had suffered a fever, cough or other symptoms of a lung infection

At a news conference with three of his doctors, Mr. Quayle's wife, [Marilyn Quayle], said yesterday that she and they were 'very optimistic' about his prognosis and that the ailment would not affect his political plans. The 47-year-old former Vice President is expected to announce a bid for the 1996 Republican Presidential nomination in the next few weeks. Mr. Quayle's doctors said they did not know why his clot had developed. In an otherwise healthy person, which is the way they described their patient, a pulmonary embolism may result from sitting in one position for a long period of time -- on a long airplane trip, for instance. Mr. Quayle has recently traveled the country promoting his book 'Standing Firm,' about his life in politics. 'That is the first thing you think about in somebody who is healthy' and who has been traveling a lot, said Dr. Gary W. Hunninghake, an expert in lung diseases at the University of Iowa who is not connected with Mr. Quayle's case

Yesterday afternoon, with three of her husband's doctors standing by her side, Marilyn Quayle said she and the doctors were 'very optimistic' about Quayle's prognosis and that the condition would not affect his political plans. Quayle is expected to announce a run for the Republican nomination for president in the next few weeks. The previous day, Quayle had not felt well and had gone to the hospital emergency room for a chest x-ray. The doctors diagnosed walking pneumonia, said Ann Hathaway, executive director of his political action committee. She said Quayle was sent home with a prescription for a medication that she did not name. He returned to the hospital Monday because of the breathing difficulty

Yesterday afternoon, with three of her husband's doctors standing by her side, Marilyn Quayle said that she and the doctors were 'very optimistic' about Quayle's prognosis and that the condition will not affect his political plans. Quayle is expected to announce a run for the Republican nomination for president in the next few weeks. The previous day, Quayle had not felt well and had gone to the hospital emergency room for a chest x-ray. The doctors diagnosed walking pneumonia, said Ann Hathaway, executive director of Quayle's political action committee. She said Quayle was sent home with a prescription for a medication that she did not name. He returned to the hospital Monday because of the breathing difficulty. Earlier in the day, [Pam Perry] told the Associated Press that she did not know which lung the clot was in, what caused the clot, or whether Quayle has a history of heart or circulation problems. Doctors not connected with his case said it was very difficult to assess his problem without more information

In a sharp turnaround driven by the need to stop the AIDS epidemic, the World Health Organization is moving ahead with plans for the first large trials of the two most widely tested experimental AIDS vaccines. The United States rejected plans for testing the vaccines in this country in June. The trials now being planned could involve several thousand volunteers. The experiments are aimed at determining whether the vaccines can prevent infection with HIV, not whether they can prevent AIDS in people already infected with HIV. Developing an AIDS vaccine has been a top priority for public health officials around the world since shortly after AIDS was first recognized in 1981. But the goal has become more urgent as the number of people infected with HIV has surged. The World Health Organization now estimates that 17 million people have been infected and that 4 million have AIDS. Even a vaccine with a low degree of protection would be valuable

Both vaccines have gone through the first two stages of a three-stage testing system, evaluating safety and immunologic responses. The third phase tests the vaccines' ability to protect against the disease, and the trials now being planned could involve several thousand volunteers. The experiments are aimed at determining whether the vaccines can prevent infection with H.I.V., not whether they can prevent AIDS in people already infected with H.I.V. If enough volunteers relaxed their guard against H.I.V., the incidence of H.I.V. could rise in the community. Although the concern is theoretical, Dr. [Peter Piot] said, 'we are taking it seriously,' The World Health Organization will take steps to augment community efforts for H.I.V. prevention through education and counseling and to measure the impact of a vaccine trial on a community. 'We want to make sure that we are not exposing more people to H.I.V. than before the vaccine trial,' Dr. Piot said

Developing an AIDS vaccine has been a top priority for public-health officials around the world since shortly after acquired immune deficiency syndrome was first recognized in 1981. But the goal has become more urgent as the number of people infected with HIV has surged. The WHO now estimates that 17 million people have been infected and that four million have AIDS. Even a vaccine with a low degree of protection would be valuable