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department:Medicine. General Internal Medicine

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Curriculum Innovation: A Standardized Experiential Simulation Curriculum Equips Residents to Face the Challenges of Chief Year

Zakin, Elina; Abou-Fayssal, Nada; Lord, Aaron S; Nelson, Aaron; Rostanski, Sara K; Zhang, Cen; Zabar, Sondra; Galetta, Steven L; Kurzweil, Arielle
INTRODUCTION AND PROBLEM STATEMENT/UNASSIGNED:A chief resident's role incorporates administrative, academic, and interpersonal responsibilities essential to managing a successful residency program. However, rising chief residents receive little formal exposure to leadership training. OBJECTIVES/UNASSIGNED:To (1) define leadership styles; (2) understand the effect of cultural competence on leadership styles; (3) learn effective methods to advocate as the chief resident; (4) provide effective peer feedback; (5) provide effective supervisor feedback; (6) learn effective conflict management; (7) ensure psychological safety. METHODS AND CURRICULUM DESCRIPTION/UNASSIGNED:We developed a 1-day curriculum combining didactics and simulation activities for our program's rising chief residents. Implementation of our curricular design included a morning session focusing on small groups and didactic-based lectures on specific topics pertinent to leadership, along with a debriefing of a psychometric evaluation tool administered before the curriculum day. The simulation activity consisted of 3 group objective structured clinical examination (G-OSCE) scenarios: (1) providing a struggling junior trainee with feedback; (2) debriefing an adverse clinical outcome as the team leader; (3) navigating a challenging situation with a supervising physician. Standardized participants were surveyed for specific objectives. Learners completed precurricular and postcurricular surveys on their familiarity and preparedness for their chief year. RESULTS AND ASSESSMENT DATA/UNASSIGNED:= 0.421), learner-reported use of wellness resources was noted to be reduced after the curricular intervention and remains a result of further interest for exploration. DISCUSSION AND LESSONS LEARNED/UNASSIGNED:A 1-day leadership development curriculum combining didactics and simulation is an effective means of preparing rising chief residents to succeed in their transition to this leadership role.
PMCID:11419294
PMID: 39359660
ISSN: 2771-9979
CID: 5770672

Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose Deaths

,; Samet, Jeffrey H; El-Bassel, Nabila; Winhusen, T John; Jackson, Rebecca D; Oga, Emmanuel A; Chandler, Redonna K; Villani, Jennifer; Freisthler, Bridget; Adams, Joella; Aldridge, Arnie; Angerame, Angelo; Babineau, Denise C; Bagley, Sarah M; Baker, Trevor J; Balvanz, Peter; Barbosa, Carolina; Barocas, Joshua; Battaglia, Tracy A; Beard, Dacia D; Beers, Donna; Blevins, Derek; Bove, Nicholas; Bridden, Carly; Brown, Jennifer L; Bush, Heather M; Bush, Joshua L; Caldwell, Ryan; Calver, Katherine; Calvert, Deirdre; Campbell, Aimee N C; Carpenter, Jane; Caspar, Rachel; Chassler, Deborah; Chaya, Joan; Cheng, Debbie M; Cunningham, Chinazo O; Dasgupta, Anindita; David, James L; Davis, Alissa; Dean, Tammy; Drainoni, Mari-Lynn; Eggleston, Barry; Fanucchi, Laura C; Feaster, Daniel J; Fernandez, Soledad; Figueroa, Wilson; Freedman, Darcy A; Freeman, Patricia R; Freiermuth, Caroline E; Friedlander, Eric; Gelberg, Kitty H; Gibson, Erin B; Gilbert, Louisa; Glasgow, LaShawn; Goddard-Eckrich, Dawn A; Gomori, Stephen; Gruss, Dawn E; Gulley, Jennifer; Gutnick, Damara; Hall, Megan E; Harger Dykes, Nicole; Hargrove, Sarah L; Harlow, Kristin; Harris, Aumani; Harris, Daniel; Helme, Donald W; Holloway, JaNae; Hotchkiss, Juanita; Huang, Terry; Huerta, Timothy R; Hunt, Timothy; Hyder, Ayaz; Ingram, Van L; Ingram, Tim; Kauffman, Emily; Kimball, Jennifer L; Kinnard, Elizabeth N; Knott, Charles; Knudsen, Hannah K; Konstan, Michael W; Kosakowski, Sarah; Larochelle, Marc R; Leaver, Hannah M; LeBaron, Patricia A; Lefebvre, R Craig; Levin, Frances R; Lewis, Nikki; Lewis, Nicky; Lofwall, Michelle R; Lounsbury, David W; Luster, Jamie E; Lyons, Michael S; Mack, Aimee; Marks, Katherine R; Marquesano, Stephanie; Mauk, Rachel; McAlearney, Ann Scheck; McConnell, Kristin; McGladrey, Margaret L; McMullan, Jason; Miles, Jennifer; Munoz Lopez, Rosie; Nelson, Alisha; Neufeld, Jessica L; Newman, Lisa; Nguyen, Trang Q; Nunes, Edward V; Oller, Devin A; Oser, Carrie B; Oyler, Douglas R; Pagnano, Sharon; Parran, Theodore V; Powell, Joshua; Powers, Kim; Ralston, William; Ramsey, Kelly; Rapkin, Bruce D; Reynolds, Jennifer G; Roberts, Monica F; Robertson, Will; Rock, Peter; Rodgers, Emma; Rodriguez, Sandra; Rudorf, Maria; Ryan, Shawn; Salsberry, Pamela; Salvage, Monika; Sabounchi, Nasim; Saucier, Merielle; Savitzky, Caroline; Schackman, Bruce; Schady, Elizabeth; Seiber, Eric E; Shadwick, Aimee; Shoben, Abigail; Slater, Michael D; Slavova, Svetla; Speer, Drew; Sprunger, Joel; Starbird, Laura E; Staton, Michele; Stein, Michael D; Stevens-Watkins, Danelle J; Stopka, Thomas J; Sullivan, Ann; Surratt, Hilary L; Sword Cruz, Rachel; Talbert, Jeffery C; Taylor, Jessica L; Thompson, Katherine L; Vandergrift, Nathan; Vickers-Smith, Rachel A; Vietze, Deanna J; Walker, Daniel M; Walley, Alexander Y; Walters, Scott T; Weiss, Roger; Westgate, Philip M; Wu, Elwin; Young, April M; Zarkin, Gary A; Walsh, Sharon L
BACKGROUND:Evidence-based practices for reducing opioid-related overdose deaths include overdose education and naloxone distribution, the use of medications for the treatment of opioid use disorder, and prescription opioid safety. Data are needed on the effectiveness of a community-engaged intervention to reduce opioid-related overdose deaths through enhanced uptake of these practices. METHODS:In this community-level, cluster-randomized trial, we randomly assigned 67 communities in Kentucky, Massachusetts, New York, and Ohio to receive the intervention (34 communities) or a wait-list control (33 communities), stratified according to state. The trial was conducted within the context of both the coronavirus disease 2019 (Covid-19) pandemic and a national surge in the number of fentanyl-related overdose deaths. The trial groups were balanced within states according to urban or rural classification, previous overdose rate, and community population. The primary outcome was the number of opioid-related overdose deaths among community adults. RESULTS:During the comparison period from July 2021 through June 2022, the population-averaged rates of opioid-related overdose deaths were similar in the intervention group and the control group (47.2 deaths per 100,000 population vs. 51.7 per 100,000 population), for an adjusted rate ratio of 0.91 (95% confidence interval, 0.76 to 1.09; P = 0.30). The effect of the intervention on the rate of opioid-related overdose deaths did not differ appreciably according to state, urban or rural category, age, sex, or race or ethnic group. Intervention communities implemented 615 evidence-based practice strategies from the 806 strategies selected by communities (254 involving overdose education and naloxone distribution, 256 involving the use of medications for opioid use disorder, and 105 involving prescription opioid safety). Of these evidence-based practice strategies, only 235 (38%) had been initiated by the start of the comparison year. CONCLUSIONS:In this 12-month multimodal intervention trial involving community coalitions in the deployment of evidence-based practices to reduce opioid overdose deaths, death rates were similar in the intervention group and the control group in the context of the Covid-19 pandemic and the fentanyl-related overdose epidemic. (Funded by the National Institutes of Health; HCS ClinicalTrials.gov number, NCT04111939.).
PMCID:11761538
PMID: 38884347
ISSN: 1533-4406
CID: 5791882

Colesevelam for lenalidomide associated diarrhea in patients with multiple myeloma [Letter]

Hultcrantz, Malin; Hassoun, Hani; Korde, Neha; MacLachlan, Kylee; Mailankody, Sham; Patel, Dhwani; Shah, Urvi A; Tan, Carlyn Rose; Chung, David J; Lahoud, Oscar B; Landau, Heather J; Scordo, Michael; Shah, Gunjan L; Giralt, Sergio A; Pianko, Matthew J; Burge, Miranda; Barnett, Kelly; Salcedo, Meghan; Caple, Julia; Tran, Linh; Blaslov, Jenna; Shekarkhand, Tala; Hamid, Selena; Nemirovsky, David; Derkach, Andriy; Arisa, Oluwatobi; Peer, Cody J; Figg, William D; Usmani, Saad Z; Landgren, Ola; Lesokhin, Alexander M
PMID: 39300066
ISSN: 2044-5385
CID: 5818462

Implementing a Diet Risk Score (DRS) for Spanish-Speaking Adults in a Clinical Setting: A Feasibility Study

Johnston, Emily A; Torres, Maria; Hansen, John; Ochoa, Kimberly; Mortenson, Daniel; De Leon, Elaine; Beasley, Jeannette M
Tools to briefly assess diet among US Spanish-speaking adults are needed to identify individuals at risk for cardiometabolic disease (CMD) related to diet. Two registered dietitian nutritionists (RDNs) recruited bilingual medical students to translate the validated Diet Risk Score (DRS) into Spanish (DRS-S). Participants were recruited from a federally qualified health center. Students administered the DRS-S and one 24-h recall (Automated Self-Administered 24-Hour (ASA24®) Dietary Assessment Tool) on one day; a second recall was administered within 1 week. Recalls were scored using the Healthy Eating Index (HEI)-2015, a measure of adherence to the Dietary Guidelines for Americans. Spearman correlations, weighted kappa, and ANOVA were conducted using SAS 9.4 to assess the relative validity of the DRS-S. Thirty-one Spanish-speaking adults (female: n = 17, 53%; mean age: 58 (42-69)) completed assessments. The mean DRS-S was 9 (SD = 4.2) (max: 27; higher score = higher risk) and the mean HEI-2015 score was 65.7 (SD = 9.7) (max: 100; higher score = lower risk), with significant agreement between measures (r: -0.45 (p = 0.01)), weighted kappa: -0.3 (p = 0.03). The DRS-S can be used in resource-constrained settings to assess diet for intervention and referral to RDNs. The DRS-S should be tested in clinical care to assess the impact of dietary changes to reduce CMD risk.
PMCID:11396789
PMID: 39275307
ISSN: 2072-6643
CID: 5690892

Implementing and monitoring high-quality community health worker care in adult primary care at New York City Health + Hospitals

Clapp, Jenifer; Calvo-Friedman, Alessandra; Tan, Yuan Jin; Kumar, Samantha Lily; Lupi, Jenna; Conley, David; Perdomo, Evelyn; Davis, Nichola J
BACKGROUND:This study describes how New York City (NYC) Health + Hospitals implemented a large-scale Community Health Worker (CHW) program in adult primary care clinics between January 2022 and December 2023 and established metrics to monitor program implementation. This study is timely as healthcare systems consider how to scale high-quality CHW programs. METHODS:We collected metrics in the following areas: (1) Workforce demographics, team structure, and training; (2) Enrolled patient demographics; (3) Patient-centered metrics, such as patient counts (e.g. patients outreached and enrolled) and engagement (e.g. median time in program, caseloads per CHW), and goals (e.g. median number of goals identified and completed). Metrics are based on standard data elements captured through CHW documentation in the electronic health record collected during program implementation. Data cleaning is completed using SQL queries and R scripts. RESULTS:In June 2023, there were a total of 97 CHW and 22 CHW Supervisor staff lines in adult primary care across 17 healthcare sites. There were 4.6 CHWs to 1 CHW supervisor on average though this ranged by facility from 1:1 to 1:6. Compared to the population that receives primary care at NYC H + H, CHWs served more African American/Black patients (40% vs. 32%) and an older patient population (35% older than 65 vs. 21% older than 65). From January 2022 to December 2023, 13,812 patients were outreached by CHWs. Of these, 9,069 (66%) were referred by clinicians, 7,331 (53%) were enrolled, and 5,044 (37%) successfully graduated. The median number of goals identified by patients was four, and the median number of goals completed with a CHW per patient was three. The top three goals were primary care engagement (47%), specialty care engagement (46%), and food insecurity (45%). CONCLUSION/CONCLUSIONS:Establishing clear implementation and process metrics helps to ensure that CHWs embedded in health systems can meaningfully engage adult patients in health care, address patient-centered goals, and connect patients to community and government services.
PMCID:11367903
PMID: 39223531
ISSN: 2731-4553
CID: 5687702

Trends in Transcatheter Aortic Valve Implantation Utilization, Outcomes, and Healthcare Resource Use in Patients With Liver Cirrhosis: A Decade of Insights (2011-2020)

Krittanawong, Chayakrit; Wang, Yichen; Qadeer, Yusuf Kamran; Chen, Bing; Wang, Zhen; Al-Azzam, Fu'ad; Alam, Mahboob; Sharma, Samin; Jneid, Hani
It is well known that individuals with liver cirrhosis are considered at high risk for cardiac surgery, with an increased risk for morbidity and mortality as the liver disease progresses. In the last decade, there have been considerable advances in transcatheter aortic valve implantation (TAVI) as an alternative to surgical aortic valve replacement (SAVR) in individuals deemed to be at high risk for surgery. However, research surrounding TAVI in the setting of liver cirrhosis has not been as widely studied. In this national population-based cohort study, we evaluated the trends of mortality, complications, and healthcare utilization in liver cirrhotic patients undergoing TAVI, as well as analyzed the basic demographics of these individuals. We found that from 2011 to 2020, the amount of TAVI procedures conducted in cirrhotic patients was increasing annually, while mortality, procedural complications, and healthcare utilization trends in these cirrhotic patients undergoing TAVI decreased. Overall, TAVI does seem to be reasonable management for aortic stenosis patients with liver cirrhosis who need aortic valve replacement.
PMID: 38598544
ISSN: 1535-2811
CID: 5679962

Evaluation of GPT-4 ability to identify and generate patient instructions for actionable incidental radiology findings

Woo, Kar-Mun C; Simon, Gregory W; Akindutire, Olumide; Aphinyanaphongs, Yindalon; Austrian, Jonathan S; Kim, Jung G; Genes, Nicholas; Goldenring, Jacob A; Major, Vincent J; Pariente, Chloé S; Pineda, Edwin G; Kang, Stella K
OBJECTIVES/OBJECTIVE:To evaluate the proficiency of a HIPAA-compliant version of GPT-4 in identifying actionable, incidental findings from unstructured radiology reports of Emergency Department patients. To assess appropriateness of artificial intelligence (AI)-generated, patient-facing summaries of these findings. MATERIALS AND METHODS/METHODS:Radiology reports extracted from the electronic health record of a large academic medical center were manually reviewed to identify non-emergent, incidental findings with high likelihood of requiring follow-up, further sub-stratified as "definitely actionable" (DA) or "possibly actionable-clinical correlation" (PA-CC). Instruction prompts to GPT-4 were developed and iteratively optimized using a validation set of 50 reports. The optimized prompt was then applied to a test set of 430 unseen reports. GPT-4 performance was primarily graded on accuracy identifying either DA or PA-CC findings, then secondarily for DA findings alone. Outputs were reviewed for hallucinations. AI-generated patient-facing summaries were assessed for appropriateness via Likert scale. RESULTS:For the primary outcome (DA or PA-CC), GPT-4 achieved 99.3% recall, 73.6% precision, and 84.5% F-1. For the secondary outcome (DA only), GPT-4 demonstrated 95.2% recall, 77.3% precision, and 85.3% F-1. No findings were "hallucinated" outright. However, 2.8% of cases included generated text about recommendations that were inferred without specific reference. The majority of True Positive AI-generated summaries required no or minor revision. CONCLUSION/CONCLUSIONS:GPT-4 demonstrates proficiency in detecting actionable, incidental findings after refined instruction prompting. AI-generated patient instructions were most often appropriate, but rarely included inferred recommendations. While this technology shows promise to augment diagnostics, active clinician oversight via "human-in-the-loop" workflows remains critical for clinical implementation.
PMID: 38778578
ISSN: 1527-974x
CID: 5654832

Recommendations for Faculty Development in Addressing Implicit Bias in Clinical Encounters and Clinical Learning Environments [Editorial]

Gonzalez, Cristina M; Greene, Richard E; Cooper, Lisa A; Lypson, Monica L
PMID: 38831249
ISSN: 1525-1497
CID: 5665122

Clinical implications of combination proton pump inhibitor and triple therapies in patients with atrial fibrillation following percutaneous intervention: a guide for clinicians

Gries, Jacob J; Chen, Bing; Virk, Hafeez Ul Hassan; Khalid, Umair; Jneid, Hani; Birnbaum, Yochai; Lavie, Carl J; Krittanawong, Chayakrit
INTRODUCTION/UNASSIGNED:Patients on systemic oral anticoagulation with vitamin K antagonists (VKA) or non-vitamin K oral anticoagulants (NOAC) often require triple therapy following percutaneous coronary intervention, substantially increasing the risk of bleeding. Gastroprotective agents like proton pump inhibitors (PPI) are often employed to mitigate this risk, despite potential competitive inhibition between P2Y12-receptor inhibitors, NOACs, and VKAs. While the interactions and clinical outcomes of PPIs and DAPT have been frequently explored in literature, not many studies have evaluated the same outcomes for triple therapy. AREAS COVERED/UNASSIGNED:This comprehensive narrative review of three studies on PPIs and triple from the PubMed/MEDLINE database supplemented by 23 other relevant studies aims to use the available literature to analyze the potential interactions between PPIs and triple therapy while shedding light on their mechanisms, clinical implications, and areas for optimization. EXPERT OPINION/UNASSIGNED:If triple therapy is indicated following PCI, then patients at high-risk for bleeding may benefit from transition to apixaban and a PPI to lower the risk of gastrointestinal bleeding. More research is needed to determine the role of PPIs in triple therapies in prevention of gastrointestinal bleeding or potentiation of other adverse outcomes.
PMID: 39267388
ISSN: 1744-8344
CID: 5719352

Assessment of Medical Education on Transgender Health: A Scoping Literature Review

Dubin, Samuel; Kutscher, Eric; Nolan, Ian; Levitt, Nathan; Cook, Tiffany E; Greene, Richard E
Little is known about how physician learners are assessed following educational interventions about providing gender-affirming care to transgender and gender diverse (TGD) people. The inclusion of learner assessments with educational interventions is essential to understand and measure health professionals' knowledge and skills. We seek to describe how the medical literature has approached the assessment of learners following educational interventions about TGD health. A scoping literature review was done. The guiding research question was "What are the current learner-assessment practices in medical education pedagogy about TGD health?" A total of 270 manuscripts were reviewed. 17 manuscripts were included for data extraction. Miller's pyramid was used to categorize results. 15 used pre- and post-intervention knowledge questionaries to assess learners. Six used simulated patient encounters to assess learners. Most assessments of TGD knowledge and skills among physician learners are pre- and post-surveys. There is sparse literature on higher level assessment following educational interventions that demonstrate learner skills, behaviors, or impact on patient outcomes. Discrete, one-time interventions that are lecture or workshop-based have yet to rigorously assess learners' ability to provide clinical care to TGD patients that is both culturally humble and clinically astute.
PMID: 37966355
ISSN: 1552-3918
CID: 5729322