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department:Medicine. General Internal Medicine

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Metabolic syndrome and kidney disease

Chapter by: Kramer, Holly J.; Joshi, Shivam
in: Nutritional Management of Renal Disease, Fourth Edition by
[S.l.] : Elsevier, 2021
pp. 763-777
ISBN: 9780128185414
CID: 5369602

Nutritional approaches and plant-dominant diets for conservative and preservative management of chronic kidney disease

Chapter by: Joshi, Shivam; Brown-Tortorici, Amanda; Sussman-Dabach, Elizabeth J.; Kalantar-Zadeh, Kamyar
in: Nutritional Management of Renal Disease, Fourth Edition by
[S.l.] : Elsevier, 2021
pp. 515-543
ISBN: 9780128185414
CID: 5369572

Telemedicine Training in the COVID Era: Revamping a Routine OSCE to Prepare Medicine Residents for Virtual Care

Boardman, Davis; Wilhite, Jeffrey A; Adams, Jennifer; Sartori, Daniel; Greene, Richard; Hanley, Kathleen; Zabar, Sondra
Background/UNASSIGNED:During the rapid onset of the pandemic, clinicians transitioned from traditional outpatient practice to virtual modalities for providing routine care to patient panels. Like training programs nationwide, telemedicine training and assessment had not been systematically incorporated into our residency. In response, a scheduled Internal Medicine (IM) Objective Structured Clinical Examination (OSCE) was adapted to a remote modality to become virtual care-focused learning experience for trainees and to provide valuable feedback to educators. Methods/UNASSIGNED:Standardized Patients (SPs) rated residents on their communication (including information gathering, relationship development and patient education), patient activation and satisfaction, and telemedicine skills. Analyses included a comparison of domain scores for residents who participated in both the 2020 remote and 2019 in-person OSCEs, and a review of written resident comments about the virtual OSCE. Results/UNASSIGNED: = .008). Conclusion/UNASSIGNED:Our reformulated OSCE accomplished 3 goals including; (1) physically distancing residents from SPs per COVID regulations, (2) providing residents with the opportunity to practice critical virtual visit skills, and (3) alerting our educators to curricular improvement areas. Our methods are useful for other institutions and have applications to the larger medical education community.
PMCID:8212360
PMID: 34189270
ISSN: 2382-1205
CID: 4950972

The case for simplifying and using absolute targets for viral hepatitis elimination goals

Abaalkhail, Faisal; Abbas, Zaigham; Abdallah, Ayat; Abrao Ferreira, Paulo; Abu Raddad, Laith Jamal; Adda, Danjuma; Agarwal, Kosh; Aghemo, Alessio; Ahmed, Aijaz; Al-Busafi, Said A; Al-Hamoudi, Waleed; Al-Kaabi, Saad; Al-Romaihi, Hamad; Aljarallah, Badr; AlNaamani, Khalid; Alqahtani, Saleh; Alswat, Khalid; Altraif, Ibrahim; Asselah, Tarik; Bacon, Bruce; Bessone, Fernando; Bizri, Abdul Rahman; Blach, Sarah; Block, Tim; Bonino, Ferruccio; Brandão-Mello, Carlos Eduardo; Brown, Kimberly; Bruggmann, Philip; Brunetto, Maurizia Rossana; Buti, Maria; Cabezas, Joaquín; Calleja, Jose Luis; Castro Batänjer, Erika; Chan, Henry Lik-Yuen; Chang, Henry; Chen, Chien-Jen; Christensen, Peer Brehm; Chuang, Wan-Long; Cisneros, Laura; Cohen, Chari; Colombo, Massimo; Conway, Brian; Cooper, Curtis; Craxi, Antonio; Crespo, Javier; Croes, Esther; Cryer, Donna; Cupertino de Barros, Fernando Passos; Derbala, Moutaz; Dillon, John; Doss, Wahid; Dou, Xiaoguang; Doyle, Joseph; Duberg, Ann-Sofi; Dugan, Ellen; Dunn, Rick; Dusheiko, Geoffrey; El Khayat, Hisham; El-Sayed, Manal H; Eshraghian, Ahad; Esmat, Gamal; Esteban Mur, Rafael; Ezzat, Sameera; Falconer, Karolin; Fassio, Eduardo; Ferrinho, Paulo; Flamm, Steven; Flisiak, Robert; Foster, Graham; Fung, James; García-Samaniego, Javier; Gish, Robert G; Gonçales, Fernando; Halota, Waldemar; Hamoudi, Waseem; Hassany, Mohamed; Hatzakis, Angelos; Hay, Susan; Himatt, Sayed; Hoepelman, I M; Hsu, Yao-Chun; Hui, Yee Tak; Hunyady, Bela; Jacobson, Ira; Janjua, Naveed; Janssen, Harry; Jarcuska, Peter; Kabagambe, Kenneth; Kanto, Tatsuya; Kao, Jia-Horng; Kaymakoglu, Sabahattin; Kershenobich, David; Khamis, Faryal; Kim, Do Young; Kim, Dong Joon; Kondili, Loreta A; Kottilil, Shyamasundaran; Kramvis, Anna; Kugelmas, Marcelo; Kurosaki, Masayuki; Lacombe, Karine; Lagging, Martin; Lao, Wai-Cheung; Lavanchy, Daniel; Lazarus, Jeffrey V; Lee, Alice; Lee, Samual S; Levy, Miriam; Liakina, Valentina; Lim, Young-Suk; Liu, Shuang; Maddrey, Willis; Malekzadeh, Reza; Marinho, Rui Tato; Mathur, Poonam; Maticic, Mojca; Mendes Correa, Maria Cassia; Mera, Jorge; Merat, Shahin; Mogawer, Sherif; Mohamed, Rosmawati; Mostafa, Ibrahim; Muellhaupt, Beat; Muljono, David; Nahum, Mendez Sanchez; Nawaz, Arif; Negro, Francesco; Ninburg, Michael; Ning, Qing; Ntiri-Reid, Boatemaa; Nymadawa, Pagbajabyn; Oevrehus, Anne; Ormeci, Necati; Orrego, Mauricio; Osman, Alaa; Oyunsuren, Tsendsuren; Pan, Calvin; Papaevangelou, Vassiliki; Papatheodoridis, George; Popping, Stephanie; Prasad, Papu; Prithiviputh, Rittoo; Qureshi, Huma; Ramji, Alnoor; Razavi, Homie; Razavi-Shearer, Devin; Razavi-Shearer, Kathryn; Reddy, Rajender; Remak, William; Richter, Clemens; Ridruejo, Ezequiel; Robaeys, Geert; Roberts, Lewis; Roberts, Stuart; Roudot-Thoraval, Françoise; Saab, Sammy; Said, Sanaa; Salamat, Amjad; Sanai, Faisal; Sanchez-Avila, Juan Francisco; Schiff, Eugene; Schinazi, Raymond; Sebastiani, Giada; Seguin-Devaux, Carole; Shanmugam, R P; Sharara, Ala; Shilton, Sonjelle; Shouval, Daniel; Sievert, William; Simonova, Marieta; Sohrabpour, Amir Ali; Sonderup, Mark; Soza, Alejandro; Steinfurth, Nancy; Sulkowski, Mark; Tan, Soek-Siam; Tanaka, Junko; Tashi, Dhondup; Thein, Hla-Hla; Thompson, Peyton; Tolmane, Ieva; Toy, Mehlika; Valantinas, Jonas; Van de Vijver, David; Vince, Adriana; Vélez-Möller, Patricia; Waked, Imam; Wang, Su; Wedemeyer, Heiner; Wendy Spearman, C; Wong, Vincent; Xie, Qing; Yamada, Seiji; Yang, Hwai-I; Yesmembetov, Kakharman; Yilmaz, Yusuf; Younossi, Zobair; Yu, Ming-Lung; Yuen, Man-Fung; Yurdaydin, Cihan; Yusuf, Aasim; Zekry, Amany; Zeuzem, Stefan
The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries' progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to ≤5 per 100 000, reduce HBV prevalence among 1-year-olds to ≤0.1%, reduce HBV and HCV mortality to ≤5 per 100 000, and demonstrate HBV and HCV year-to-year decrease in new HCV- and HBV-related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit.
PMID: 32979881
ISSN: 1365-2893
CID: 4679282

Multi-Level Predictors of Discharges Against Medical Advice: Identifying Contributors to Variation Using an All-Payer Database

Onukwugha, Eberechukwu; Nagarajan, Madhu; Offurum, Ada; Gulati, Mangla; Alfandre, David
ABSTRACT/UNASSIGNED:There is increasing evidence of the role of non-patient-level factors on discharge against medical advice (DAMA), but limited quantitative information regarding the extent of their impact. This study quantifies the contribution of discharge-level and hospital-level factors to the variation in DAMA. We grouped variables from the 2014 National Inpatient Sample data and ran incremental mixed-effects logit models with grouping at the level of the discharge, the hospital, and the census region. We obtained the intraclass correlation coefficients (ICCs), and evaluated the incremental change in ICC. The final sample included 2,687,430 discharges. 12.8% of the identified variation in the probability of DAMA was associated with the hospital, and 1.2% of the variation was associated with the census division in which the hospital was located. The final, fully-adjusted model had 7.3% of variation in DAMA associated with the hospital-level, with the greatest percentage reductions because of the addition of patient demographics. Even after adjusting for measured patient-level characteristics, there was a contribution of non-patient-level factors to DAMA outcomes. The findings identify a role for a multi-level approach to addressing DAMA.
PMID: 32134810
ISSN: 1945-1474
CID: 4774092

Prognostic value of coronary artery calcium score, area, and density among individuals on statin therapy vs. non-users: The coronary artery calcium consortium

Osei, Albert D; Mirbolouk, Mohammadhassan; Berman, Daniel; Budoff, Matthew J; Miedema, Michael D; Rozanski, Alan; Rumberger, John A; Shaw, Leslee; Al Rifai, Mahmoud; Dzaye, Omar; Graham, Garth N; Banach, Maciej; Blumenthal, Roger S; Dardari, Zeina A; Nasir, Khurram; Blaha, Michael J
BACKGROUND AND AIMS:Statins do not decrease coronary artery calcium (CAC) and may increase existing calcification or its density. Therefore, we examined the prognostic significance of CAC among statin users at the time of CAC scanning. METHODS:We included 28,025 patients (6151 statin-users) aged 40-75 years from the CAC Consortium. Cox regression models were used to assess the association of CAC with coronary heart disease (CHD) and cardiovascular disease (CVD) mortality. Models were adjusted for traditional CVD risk factors. Additionally, we examined the predictive performance of CAC components including CAC area, volume, and density using an age- and sex-adjusted Cox regression model. RESULTS:Participants (mean age 53.9 ± 10.3 years, 65.0% male) were followed for median 11.2 years. There were 395 CVD and 182 CHD deaths. One unit increase in log CAC score was associated with increased risk of CVD mortality (hazard ratio (HR), 1.2; 95% CI = 1.1-1.3) and CHD mortality (HR, 1.2; 95% CI = 1.1-1.4)) among statin users. There was a small but significant negative interaction between CAC score and statin use for the prediction of CHD (p-value = 0.036) and CVD mortality (p-value = 0.025). The volume score and CAC area were similarly associated with outcomes in statin users and non-users. Density was associated with CVD and CHD mortality in statin naïve patients, but with neither in statin users. CONCLUSION:CAC scoring retains robust risk prediction in statin users, and the changing relationship of CAC density with outcomes may explain the slightly weaker relationship of CAC with outcomes in statin users.
PMID: 33121743
ISSN: 1879-1484
CID: 4961742

Coronary Artery Calcium Scores I [Letter]

Fakheri, Robert J
PMID: 33413826
ISSN: 1942-5546
CID: 4739322

COVID-19 in New Orleans: A Nephrology Clinical and Education Perspective and Lessons Learned

Naljayan, Mihran; Yazdi, Farshid; Struthers, Sarah; Sharshir, Moh'd; Williamson, Amanda; Simon, Eric E
New Orleans' first case of COVID-19 was reported on March 9, 2020 with a subsequent rapid rise in the number of cases throughout the state of Louisiana. Traditional educational efforts were no longer viable with social distancing and stay-at-home orders, therefore virtual didactics were integrated into our curriculum. Due to an exponential increase in the number of patients with acute kidney injury requiring kidney replacement therapy, the nephrology sections at Louisiana State University School of Medicine and Tulane University School of Medicine adapted their clinical workflows to accommodate these increased clinical volumes by utilizing prolonged intermittent kidney replacement therapies and acute peritoneal dialysis as well as other strategies to mitigate nursing burnout and decrease scarce resource utilization. Telehealth was implemented in outpatient clinics and dialysis units to protect vulnerable patients with kidney disease while maintaining access to care. Lessons learned from this pandemic and subsequent response may be utilized for future responses in similar situations.
PMCID:7708233
PMID: 33283183
ISSN: 2590-0595
CID: 4708532

Practice of Psycho-oncology with Latino Patients: An International Study

Costas-Muñiz, Rosario; Castro-Figueroa, Eida; Torres, Normarie; Claros, Maria; Galindo-Vazquez, Oscar; Narang, Bharat; Gany, Francesca M
Cancer is the second leading cause of death globally, approximately 70% of deaths from cancer occur in low- and middle-income countries.1 About 1.3 million new cancer cases and 666,000 cancer deaths were estimated to have occurred in 2018 in Latin America and the Caribbean. Cancer is also the leading cause of death of Latinos in the U.S., accounting for approximately 42,700 deaths/year in the U.S. Latino population.2 This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
PMID: 32914912
ISSN: 1099-1611
CID: 4589592

Toward Understanding Movement-evoked Pain (MEP) and its Measurement: A Scoping Review

Fullwood, Dottington; Means, Sydney; Merriwether, Ericka N; Chimenti, Ruth L; Ahluwalia, Simar; Booker, Staja Q
OBJECTIVE:Individuals with chronic pain conditions often report movement as exacerbating pain. An increasing number of researchers and clinicians have recognized the importance of measuring and distinguishing between movement-evoked pain (MEP) and pain at rest as an outcome. This scoping review maps the literature and describes MEP measurement techniques. METHOD/METHODS:The scoping review utilized six databases to identify original studies that targeted pain or movement-related outcomes. Our search returned 7,322 articles that were screened by title and abstract by two reviewers. The inclusion criteria focused on measurement of MEP before, during and after movement tasks in adults with chronic pain. Studies of children < 18 years of age or with non-human animals, case studies, qualitative studies, book chapters, cancer-related pain, non-English language and abstracts with no full publish text were excluded from the study. RESULTS:Results from 38 studies revealed great variation in the measurement of MEP, while almost all of the studies did not provide an explicit conceptual or operational definition for MEP. Additionally, studies collectively illuminated differences in MEP compared to rest pain, movement provocation methods, and pain intensity as the primary outcome. DISCUSSION/CONCLUSIONS:These results have clinically significant and research implications. To advance the study of MEP, we offer that consistent terminology, standardized measurement (appropriate for pain type/population), and clear methodological processes be provided in research publications. Based on the findings, we have put forth a preliminary definition MEP which may benefit from continued scholarly dialogue.
PMID: 33093342
ISSN: 1536-5409
CID: 4661002