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department:Medicine. General Internal Medicine

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Public Health Management of Persons Under Investigation for Ebola Virus Disease in New York City, 2014-2016

Winters, Ann; Iqbal, Maryam; Benowitz, Isaac; Baumgartner, Jennifer; Vora, Neil M; Evans, Laura; Link, Nate; Munjal, Iona; Ostrowsky, Belinda; Ackelsberg, Joel; Balter, Sharon; Dentinger, Catherine; Fine, Anne D; Harper, Scott; Landman, Keren; Laraque, Fabienne; Layton, Marcelle; Slavinski, Sally; Weiss, Don; Rakeman, Jennifer L; Hughes, Scott; Varma, Jay K; Lee, Ellen H
During 2014-2016, the largest outbreak of Ebola virus disease (EVD) in history occurred in West Africa. The New York City Department of Health and Mental Hygiene (DOHMH) worked with health care providers to prepare for persons under investigation (PUIs) for EVD in New York City. From July 1, 2014, through December 29, 2015, we classified as a PUI a person with EVD-compatible signs or symptoms and an epidemiologic risk factor within 21 days before illness onset. Of 112 persons who met PUI criteria, 74 (66%) sought medical care and 49 (44%) were hospitalized. The remaining 38 (34%) were isolated at home with daily contact by DOHMH staff members. Thirty-two (29%) PUIs received a diagnosis of malaria. Of 10 PUIs tested, 1 received a diagnosis of EVD. Home isolation minimized unnecessary hospitalization. This case study highlights the importance of developing competency among clinical and public health staff managing persons suspected to be infected with a high-consequence pathogen.
PMID: 31424330
ISSN: 1468-2877
CID: 4075772

The impact of a pulmonary embolism response team on the efficiency of patient care in the emergency department

Wright, Colin; Elbadawi, Ayman; Chen, Yu Lin; Patel, Dhwani; Mazzillo, Justin; Acquisto, Nicole; Groth, Christine; Van Galen, Joseph; Delehanty, Joseph; Pietropaoli, Anthony; Trawick, David; James White, R; Cameron, Pamela; Gosev, Igor; Barrus, Bryan; Kumar, Neil G; Cameron, Scott J
The concept of a pulmonary embolism response team (PERT) is multidisciplinary, with the hope that it may positively impact patient care, hospital efficiency, and outcomes in the treatment of patients with intermediate and high risk pulmonary embolism (PE). Clinical characteristics of a baseline population of patients presenting with submassive and massive PE to URMC between 2014 and 2016 were examined (n = 159). We compared this baseline population before implementation of a PERT to a similar population of patients at 3-month periods, and then as a group at 18 months after PERT implementation (n = 146). Outcomes include management strategies and efficiency of the emergency department (ED) in diagnosing, treating, and dispositioning patients. Before PERT, patients with submassive and massive PE were managed fairly conservatively: heparin alone (85%), or additional advanced therapies (15%). Following PERT, submassive and massive PE were managed as follows: heparin alone (68%), or additional advanced therapies (32%). Efficiency of the ED in managing high risk PE significantly improved after PERT compared with before PERT; where triage to diagnosis time was reduced (384 vs. 212 min, 45% decrease, p = 0.0001), diagnosis to heparin time was reduced (182 vs. 76 min, 58% decrease, p = 0.0001), and the time from triage to disposition was reduced (392 vs. 290 min, 26% decrease, p < 0.0001). Our analysis showed that following PERT implementation, patients with intermediate and high risk acute PE received more aggressive and advanced treatment modalities and received significantly expedited care in the ED.
PMID: 31102160
ISSN: 1573-742x
CID: 3927042

Computer self-administered screening for substance use in university student health centers

McNeely, Jennifer; Haley, Sean J; Smith, Allison J; Leonard, Noelle R; Cleland, Charles M; Ferdschneider, Marcy; Calderoni, Michele; Sleiter, Luke; Ciotoli, Carlo; Adam, Angéline
OBJECTIVE:To characterize the prevalence of tobacco, alcohol, and drug use and the acceptability of screening in university health centers. PARTICIPANTS/METHODS:Five hundred and two consecutively recruited students presenting for primary care visits in February and August, 2015, in two health centers. METHODS:Participants completed anonymous substance use questionnaires in the waiting area, and had the option of sharing results with their medical provider. We examined screening rates, prevalence, and predictors of sharing results. RESULTS:Past-year use was 31.5% for tobacco, 67.1% for alcohol (>4 drinks/day), 38.6% for illicit drugs, and 9.2% for prescription drugs (nonmedical use). A minority (43.8%) shared screening results. Sharing was lowest among those with moderate-high risk use of tobacco (OR =0.37, 95% CI 0.20-0.69), alcohol (OR =0.48, 95% CI 0.25-0.90), or illicit drugs (OR =0.38, 95% CI 0.20-0.73). CONCLUSIONS:Screening can be integrated into university health services, but students with active substance use may be uncomfortable discussing it with medical providers.
PMID: 30240331
ISSN: 1940-3208
CID: 3300952

Understanding drivers of influenza-like illness presenteeism within training programs: A survey of trainees and their program directors

Cowman, Kelsie; Mittal, Jaimie; Weston, Gregory; Harris, Emily; Shapiro, Lauren; Schlair, Sheira; Park, Sun; Nori, Priya
BACKGROUND:Working with influenza-like illness (ILI) is pervasive throughout health care. We assessed knowledge, attitudes, and practices regarding ILI presenteeism of both postgraduate trainees and program leaders. METHODS:This survey study was conducted at the Montefiore Medical Center, Albert Einstein College of Medicine, a large academic center in the Bronx, New York. Internal medicine and subspecialty house staff and program directors completed an anonymous electronic survey between April 23 and June 15, 2018. RESULTS:A total of 197 of 400 (49%) house staff and 23 of 39 (59%) program leaders participated; 107 (54%) trainees and 6 (26%) program leaders self-reported ILI presenteeism in the past 12 months. More than 90% of trainees and program leaders reported that ILI presenteeism places others at risk. Only 9% of program leaders accurately estimated trainee ILI presenteeism prevalence. Both cited "not wanting to burden colleagues" as the top reason for ILI presenteeism. Twenty-six (24%) trainees practiced ILI presenteeism on critical care units. The majority reported that they would provide patient care with upper respiratory symptoms without fever. Most trainees incorrectly answered influenza knowledge questions. CONCLUSIONS:ILI presenteeism prevalence is high within training programs at our medical center. Program leaders can model best practices, enforce nonpunitive sick-leave policies, and ensure infection prevention competencies are met annually.
PMID: 30898375
ISSN: 1527-3296
CID: 4450002

Gamification to Motivate the Unmotivated Smoker: The "Take a Break" Digital Health Intervention

Blok, Amanda C; Sadasivam, Rajani S; Amante, Daniel J; Kamberi, Ariana; Flahive, Julie; Morley, Jeanne; Conigliaro, Joseph; Houston, Thomas K
PMCID:6686688
PMID: 31219347
ISSN: 2161-7856
CID: 4375042

Relationship between pulmonary hypertension and outcomes among patients with heart failure with reduced ejection fraction

Mene-Afejuku, Tuoyo O; Akinlonu, Adedoyin; Dumancas, Carissa; Lopez, Persio D; Cardenas, Ramiro; Sueldo, Carla; Veranyan, Shushan; Salazar, Peggy; Visco, Ferdinand; Pekler, Gerald; Mushiyev, Savi
Objectives: To identify predictors of pulmonary hypertension (PHT) and the predictive value of PHT for rehospitalization among patients with heart failure with reduced ejection fraction (HFrEF). Methods: A retrospective study of 351 hospitalized patients with heart failure (HF). Patients 18 years and above with HFrEF secondary to non-ischemic cardiomyopathy were reviewed. Patients with coronary artery disease, preserved ejection fraction and other secondary causes of PHT apart from HF were excluded. PHT as a predictor of 30-day and six-month re-admission was assessed as well as important possible predictors of PHT. Cox regression analysis, multiple linear regression as well as other statistical tools were employed as deemed appropriate. Results: Thirty-seven (37) and 99 patients were re-hospitalized within 30 days and 6 months after discharge for decompensated HF, respectively. After Cox regression analysis, higher hemoglobin reduced the odds of rehospitalization for decompensated HF (p = 0.015) within 30 days after discharge while higher pulmonary artery systolic pressure (PASP) (p = 0.002) and blood urea nitrogen (BUN) (p = 0.041) increased the odds of rehospitalization within 6 months of discharge. The predictors of the PHT among patients with HFrEF after multiple linear regression were low BMI (p = 0.027), increasing age (p = 0.006) and increased left atrial diameter (LAD) on echocardiography (p = 0.0001). Conclusion: Patients with HFrEF have a high predisposition to developing PHT if at admission, they have low BMI, dilated left atrium or are older. Patients with one or more of these attributes may need more intensive therapy to reduce the risk of developing PHT and in turn reduce readmission rates.
PMID: 31177873
ISSN: 2154-8331
CID: 4089632

Every Minute Counts-The Time Is Now to Understand Predictors of Stroke in HIV

Srinivasa, Suman; Grinspoon, Steven K
PMCID:6734098
PMID: 31517256
ISSN: 2589-5370
CID: 4088482

Five Cases of Clozapine-Associated Cardiotoxicity and Implications for Monitoring

Rhee, David W; Diuguid-Gerber, Jillian; Kondracke, Andrea
PMID: 30558796
ISSN: 1545-7206
CID: 3556942

Safety and efficacy of the use of lumen-apposing metal stents in the management of postoperative fluid collections: a large, international, multicenter study

Yang, Juliana; Kaplan, Jeremy H; Sethi, Amrita; Dawod, Enad; Sharaiha, Reem Z; Chiang, Austin; Kowalski, Thomas; Nieto, Jose; Law, Ryan; Hammad, Hazem; Wani, Sachin; Wagh, Mihir S; Yang, Dennis; Draganov, Peter V; Messallam, Ahmed; Cai, Qiang; Kushnir, Vladimir; Cosgrove, Natalie; Ahmed, Ali Mir; Anderloni, Andrea; Adler, Douglas G; Kumta, Nikhil A; Nagula, Satish; Vleggaar, Frank P; Irani, Shayan; Robles-Medranda, Carlos; El Chafic, Abdul Hamid; Pawa, Rishi; Brewer, Olaya; Sanaei, Omid; Dbouk, Mohamad; Singh, Vikesh K; Kumbhari, Vivek; Khashab, Mouen A
BACKGROUND: Multiple studies have examined the use of lumen-apposing metal stents (LAMSs) for the drainage of peripancreatic fluid collections. Data on the use of LAMSs for postoperative fluid collections (POFCs) are scarce. POFCs may lead to severe complications without appropriate treatment. We aimed to study the outcomes (technical success, clinical success, rate/severity of adverse events, length of stay, recurrence) of the use of LAMSs for the drainage of POFCs. METHODS: This international, multicenter, retrospective study involved 19 centers between January 2012 and October 2017. The primary outcome was clinical success. Secondary outcomes included technical success and rate/severity of adverse events using the ASGE lexicon. RESULTS: A total of 62 patients were included during the study period. The most common etiology of the POFCs was distal pancreatectomy (46.8 %). The mean (standard deviation) diameter was 84.5 mm (30.7 mm). The most common indication for drainage was infection (48.4 %) and transgastric drainage was the most common approach (82.3 %). Technical success was achieved in 60/62 patients (96.8 %) and clinical success in 57/62 patients (91.9 %) during a median (interquartile range) follow-up of 231 days (90 - 300 days). Percutaneous drainage was needed in 8.1 % of patients. Adverse events occurred intraoperatively in 1/62 patients (1.6 %) and postoperatively in 7/62 (11.3 %). There was no procedure-related mortality. CONCLUSION/CONCLUSIONS: This is the largest study on the use of LAMSs for POFCs. It suggests good clinical efficacy and safety of this approach. The use of LAMSs in the management of POFCs is a feasible alternative to percutaneous and surgical drainage.
PMID: 31174225
ISSN: 1438-8812
CID: 3980872

Barriers and Facilitators to the Implementation of a Mobile Insulin Titration Intervention for Patients With Uncontrolled Diabetes: A Qualitative Analysis

Rogers, Erin; Aidasani, Sneha R; Friedes, Rebecca; Hu, Lu; Langford, Aisha T; Moloney, Dana N; Orzeck-Byrnes, Natasha; Sevick, Mary Ann; Levy, Natalie
BACKGROUND:In 2016, a short message service text messaging intervention to titrate insulin in patients with uncontrolled type 2 diabetes was implemented at two health care facilities in New York City. OBJECTIVE:This study aimed to conduct a qualitative evaluation assessing barriers to and the facilitators of the implementation of the Mobile Insulin Titration Intervention (MITI) program into usual care. METHODS:We conducted in-depth interviews with 36 patients enrolled in the MITI program and the staff involved in MITI (n=19) in the two health care systems. Interviews were transcribed and iteratively coded by two study investigators, both inductively and deductively using a codebook guided by the Consolidated Framework for Implementation Research. RESULTS:Multiple facilitator themes emerged: (1) MITI had strong relative advantages to in-person titration, including its convenience and time-saving design, (2) the free cost of MITI was important to the patients, (3) MITI was easy to use and the patients were confident in their ability to use it, (4) MITI was compatible with the patients' home routines and clinic workflow, (5) the patients and staff perceived MITI to have value beyond insulin titration by reminding and motivating the patients to engage in healthy behaviors and providing a source of patient support, and (6) implementation in clinics was made easy by having a strong implementation climate, communication networks to spread information about MITI, and a strong program champion. The barriers identified included the following: (1) language limitations, (2) initial nurse concerns about the scope of practice changes required to deliver MITI, (3) initial provider knowledge gaps about the program, and (4) provider perceptions that MITI might not be appropriate for some patients (eg, older or not tech-savvy). There was also a theme that emerged during the patient and staff interviews of an unmet need for long-term additional diabetes management support among this population, specifically diet, nutrition, and exercise support. CONCLUSIONS:The patients and staff were overwhelmingly supportive of MITI and believed that it had many benefits and that it was compatible with the clinic workflow and patients' lives. Initial implementation efforts should address staff training and nurse concerns. Future research should explore options for integrating additional diabetes support for patients.
PMID: 31368439
ISSN: 2291-5222
CID: 4011252