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department:Medicine. General Internal Medicine

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Evaluation of a virtual interprofessional oral-systemic health simulation experience in nursing, dentistry, medicine, and pharmacy education

Roitman, J; Haber, J; Cipollina, J; Feldman, L; Fletcher, J; Allen, K; Crotty, K; Kudlowitz, D; Anderson, M
PURPOSE/OBJECTIVE:The annual teaching oral-systemic health (TOSH) virtual clinical simulation and case study activity exposes interprofessional teams of nurse practitioner, nurse midwifery, dental, medical, and pharmacy students to a virtual clinical simulation experience that uses oral-systemic health as a clinical exemplar for promoting interprofessional core competencies. The present study examines changes in participating students' self-reported interprofessional competencies following participation in virtual TOSH from 2020 to 2022. These findings are also compared to those from in-person TOSH (2019) to examine the equivalence of student outcomes of both the in-person and virtual programs. METHODS:A pre- and post-test evaluation design was used to examine the effectiveness of exposure to the TOSH program on self-reported attainment of interprofessional competencies for participating students using the interprofessional collaborative competency attainment scale. RESULTS:Analysis of pre- and post-surveys demonstrated statistically significant improvement in students' self-rated interprofessional experience competencies following the virtual TOSH program, which aligns with results from the in-person cohorts. Similar findings between the in-person and virtual cohorts indicated no statistically significant difference between the two formats. CONCLUSION/CONCLUSIONS:These findings demonstrate the success of TOSH in promoting attainment of interprofessional competencies among future health professionals. We encourage administrators and faculty who lead health professional programs to take advantage of using virtual simulations as an integral component of interprofessional oral health clinical experiences where students from different health professions learn from and about each other in assessing and treating patients across the lifespan.
PMID: 38400648
ISSN: 1930-7837
CID: 5634632

Measuring the development of a medical professional identity through medical school

Lusk, P; Ark, T; Crowe, R; Monson, V; Altshuler, L; Harnik, V; Buckvar-Keltz, L; Poag, M; Belluomini, P; Kalet, A
PURPOSE/UNASSIGNED:The Professional Identity Essay (PIE) is a theory and evidence-based Medical Professional Identity Formation (MPIF) measure. We describe trajectories of PIE-measured MPIF over a 4-year US medical school curriculum. METHODS/UNASSIGNED:Students write PIEs at medical school orientation, clinical clerkships orientation, and post-advanced (near graduation) clerkship. A trained evaluator assigns an overall stage score to narrative responses to nine PIE prompts (inter-rater ICC 0.83, 95% CI [0.57 - 0.96], intra-rater ICC 0.85). Distribution of PIE stage scores across time points were analyzed in the aggregate and individual students were classified as Increase, Stable (no score change) or Decrease based on the trajectories of PIE stage scores over time. RESULTS/UNASSIGNED: CONCLUSIONS/UNASSIGNED:Medical students' PIE stage scores increase over time with three distinctive trajectories. Further study is needed to explore the utility of this method for formative assessment, program evaluation, and MPIF research.
PMID: 37917985
ISSN: 1466-187x
CID: 5655422

Using Unannounced Standardized Patients to Assess Clinician Telehealth and Communication Skills at an Urban Student Health Center [Case Report]

Phillips, Zoe; Mitsumoto, Jun; Fisher, Harriet; Wilhite, Jeffrey; Hardowar, Khemraj; Robertson, Virginia; Paige, Joquetta; Shahroudi, Julie; Albert, Sharon; Li, Jacky; Hanley, Kathleen; Gillespie, Colleen; Altshuler, Lisa; Zabar, Sondra
PURPOSE/OBJECTIVE:As the COVID-19 pandemic forced most colleges and universities to go online, student health centers rapidly shifted to telehealth platforms without frameworks for virtual care provision. An urban student health center implemented a needs assessment involving unannounced standardized patients (USPs) to evaluate the integration of a new telehealth workflow and clinicians' virtual communication skills. METHODS:From April to May 2021, USPs conducted two video visits with 12 primary care and four women's health clinicians (N = 16 clinicians; 32 visits). Cases included (1) a 21-year-old female presenting for birth control with a positive Patient Health Questionaire-9 and (2) a 21-year-old male, who vapes regularly, with questions regarding safe sex with men. Clinicians were evaluated using a checklist completed by the USP immediately following the visit and a systematic chart review of the electronic health record. RESULTS:USP feedback indicates most clinicians received high ratings for general communication skills but may benefit from educational intervention in several key telemedicine skills. Clinicians struggled with using nonverbal signals to enrich communication (47% well done), acknowledging emotions (34% well done), and using video for information gathering (34% well done). Low rates of standard screenings (e.g., 63% administered the PHQ-2, <50% asked about alcohol use) suggested protocols for in-person care were not easily incorporated into telehealth practices, and clinicians may benefit from enhanced care team support. Performance reports were shared with clinicians and leadership postvisit. DISCUSSION/CONCLUSIONS:Results suggest project design and implementation is scalable and feasible for use at other institutions, offering a structured methodology that can improve general student health care.
PMID: 38430075
ISSN: 1879-1972
CID: 5691692

Machine Learning Optimization: Defining Exposome-Metabolome Associated Aerodigestive Disease

Crowley, G.; Kwon, S.; Rushing, B.; Grunig, G.; Podury, S.; McRitchie, S.; Sumner, S.; Liu, M.; Prezant, D.J.; Nolan, A.
ORIGINAL:0017193
ISSN: 2325-6621
CID: 5651842

Contemporary Prevalence of Oral Clefts in the US: Geographic and Socioeconomic Considerations

Brydges, Hilliard T; Laspro, Matteo; Verzella, Alexandra N; Alcon, Andre; Schechter, Jill; Cassidy, Michael F; Chaya, Bachar F; Iturrate, Eduardo; Flores, Roberto L
PMCID:11084882
PMID: 38731101
ISSN: 2077-0383
CID: 5734072

Long COVID incidence in adults and children between 2020 and 2023: a real-world data study from the RECOVER Initiative

Mandel, Hannah; Yoo, Yun; Allen, Andrea; Abedian, Sajjad; Verzani, Zoe; Karlson, Elizabeth; Kleinman, Lawrence; Mudumbi, Praveen; Oliveira, Carlos; Muszynski, Jennifer; Gross, Rachel; Carton, Thomas; Kim, C; Taylor, Emily; Park, Heekyong; Divers, Jasmin; Kelly, J; Arnold, Jonathan; Geary, Carol; Zang, Chengxi; Tantisira, Kelan; Rhee, Kyung; Koropsak, Michael; Mohandas, Sindhu; Vasey, Andrew; Weiner, Mark; Mosa, Abu; Haendel, Melissa; Chute, Christopher; Murphy, Shawn; O'Brien, Lisa; Szmuszkovicz, Jacqueline; Güthe, Nicholas; Santana, Jorge; De, Aliva; Bogie, Amanda; Halabi, Katia; Mohanraj, Lathika; Kinser, Patricia; Packard, Samuel; Tuttle, Katherine; Thorpe, Lorna; Moffitt, Richard
Estimates of post-acute sequelae of SARS-CoV-2 infection (PASC) incidence, also known as Long COVID, have varied across studies and changed over time. We estimated PASC incidence among adult and pediatric populations in three nationwide research networks of electronic health records (EHR) participating in the RECOVER Initiative using different classification algorithms (computable phenotypes). Overall, 7% of children and 8.5%-26.4% of adults developed PASC, depending on computable phenotype used. Excess incidence among SARS-CoV-2 patients was 4% in children and ranged from 4-7% among adults, representing a lower-bound incidence estimation based on two control groups - contemporary COVID-19 negative and historical patients (2019). Temporal patterns were consistent across networks, with peaks associated with introduction of new viral variants. Our findings indicate that preventing and mitigating Long COVID remains a public health priority. Examining temporal patterns and risk factors of PASC incidence informs our understanding of etiology and can improve prevention and management.
PMCID:11092818
PMID: 38746290
CID: 5662752

Procedural Fairness in Physician-Patient Communication: A Predictor of Health Outcomes in a Cohort of Adults with Overweight or Obesity

Wittleder, Sandra; Viglione, Clare; Reinelt, Tilman; Dixon, Alia; Jagmohan, Zufarna; Orstad, Stephanie L; Beasley, Jeannette M; Wang, Binhuan; Wylie-Rosett, Judith; Jay, Melanie
BACKGROUND:This study aimed to explore whether patients' perception of procedural fairness in physicians' communication was associated with willingness to follow doctor's recommendations, self-efficacy beliefs, dietary behaviors, and body mass index. METHODS:(43.6% Black, 40.7% Hispanic/Latino, 55.8% female, mean age = 50 years), who enrolled in a weight management study in two New York City healthcare institutions. We conducted ordinary least squares path analyses with bootstrapping to explore direct and indirect associations among procedural fairness, willingness to follow recommendations, self-efficacy, dietary behaviors, and body mass index, while controlling for age and gender. RESULTS:Serial, multiple mediator models indicated that higher procedural fairness was associated with an increased willingness to follow recommendations which, in turn, was associated with healthier dietary behaviors and a lower BMI (indirect effect =  - .02, SE = .01; 95% CI [- .04 to - .01]). Additionally, higher procedural fairness was associated with elevated dietary self-efficacy, which was, in turn, was associated with healthier dietary behaviors and lower BMI (indirect effect =  - .01, SE = .003; 95% CI [- .02 to - .002]). CONCLUSIONS:These findings highlight the importance of incorporating procedural fairness in physician-patient communication concerning weight management in diverse primary care patients.
PMID: 38609688
ISSN: 1532-7558
CID: 5676362

CD8 effector T cells enhance teclistamab response in BCMA-exposed and -naïve multiple myeloma

Firestone, Ross S; McAvoy, Devin; Shekarkhand, Tala; Serrano, Edith; Hamadeh, Issam; Wang, Alice; Zhu, Menglei; Qin, Wei Ge; Patel, Dhwani; Tan, Carlyn R; Hultcrantz, Malin; Mailankody, Sham; Hassoun, Hani; Shah, Urvi S; Korde, Neha; Maclachlan, Kylee H; Landau, Heather J; Scordo, Michael; Shah, Gunjan L; Lahoud, Oscar B; Giralt, Sergio; Murata, Kazunori; Hosszu, Kinga K; Chung, David J; Lesokhin, Alexander M; Usmani, Saad Z
Teclistamab, a B-cell maturation antigen (BCMA)- and CD3-targeting bispecific antibody, is an effective novel treatment for relapsed/refractory multiple myeloma (R/RMM), but efficacy in patients exposed to BCMA-directed therapies and mechanisms of resistance have yet to be fully delineated. We conducted a real-world retrospective study of commercial teclistamab, capturing both clinical outcomes and immune correlates of treatment response in a cohort of patients (n = 52) with advanced R/RMM. Teclistamab was highly effective with an overall response rate (ORR) of 64%, including an ORR of 50% for patients with prior anti-BCMA therapy. Pretreatment plasma cell BCMA expression levels had no bearing on response. However, comprehensive pretreatment immune profiling identified that effector CD8+ T-cell populations were associated with response to therapy and a regulatory T-cell population associated with nonresponse, indicating a contribution of immune status in outcomes with potential utility as a biomarker signature to guide patient management.
PMCID:10987849
PMID: 37878808
ISSN: 2473-9537
CID: 5647102

Antibiotic use and inflammatory bowel disease: number needed to harm? Authors' reply [Letter]

Faye, Adam S; Jess, Tine
PMID: 37226847
ISSN: 1468-3288
CID: 5543812

Initiative to reduce unnecessary routine daily testing of complete blood counts across 11 safety net hospitals

Cho, Hyung J; Israilov, Sigal; Tsega, Surafel; Alaiev, Dan; Talledo, Joseph; Chandra, Komal; Alarcon Manchego, Peter; Zaurova, Milana; Petrilli, Christopher M; Krouss, Mona
OBJECTIVES/OBJECTIVE:National societies recommend against performing routine daily laboratory testing without a specific indication. Unnecessary testing can lead to patient harm, such as hospital-acquired anemia. The objective of this study was to reduce repeat complete blood counts (CBCs) after initial testing. METHODS:This was a quality improvement initiative implemented across 11 safety net hospitals in New York City. A best practice advisory (BPA) was implemented that asked the user to remove a CBC if the last 2 CBCs within 72 hours had normal white blood cell and platelet counts and unchanged hemoglobin levels. The outcome measure was the rate of CBCs per 1000 patient days preintervention (January 8, 2020, to December 22, 2020) to postintervention (December 23, 2020, to December 7, 2021). The process measure was the acceptance rate of the BPA, defined as the number of times the repeat CBC order was removed through the BPA divided by the total number of times the BPA triggered. RESULTS:Across 11 hospitals, repeat CBC testing decreased by 12.3% (73.05 to 64.04 per 1000 patient days, P < .001). Six of the 11 hospitals exhibited statistically significant decreases, ranging from a 10% to 48.9% decrease of repeat CBCs. The overall BPA action rate was 20.0% (24,029 of 119,944 repeat CBCs). CONCLUSIONS:This low-effort, electronic health record-based intervention can effectively reduce unnecessary laboratory testing.
PMID: 38041859
ISSN: 1943-7722
CID: 5616872