Try a new search

Format these results:

Searched for:

department:Medicine. General Internal Medicine

recentyears:2

school:SOM

Total Results:

14547


Volleyball injuries

Eerkes, Kevin
There has been a significant increase in the numbers of people playing indoor and beach volleyball since the early 1980s and, consequently, an increase in injuries. Most injuries are related to repetitive jumping and hitting the ball overhead. The ankle is the most commonly injured joint, but the knee, shoulder, low back, and fingers also are vulnerable. The shoulder in particular is subject to extreme torque when hitting and jump serving the ball. Some injuries have a predilection for those playing on sand versus those playing in an indoor court. The clinician caring for volleyball players should be aware of the types of injuries these players sustain and how to help them return to play promptly and appropriately. This article reviews the specific injuries that are most common as a result of participating in the sport of volleyball.
PMID: 22965348
ISSN: 1537-890x
CID: 178825

Pasireotide

Feelders, Richard A; Yasothan, Uma; Kirkpatrick, Peter
PMID: 22850776
ISSN: 1474-1784
CID: 4002822

Indications for inferior vena cava filter placement: do physicians comply with guidelines?

Baadh, Amanjit S; Zikria, Joseph F; Rivoli, Stephen; Graham, Robert E; Javit, Daniel; Ansell, Jack E
PURPOSE: Inferior vena cava (IVC) filter placement has increased significantly over the past few decades, but indications for filter placement vary widely depending on which professional society recommendations are followed, and it is uncertain how compliant physicians are in adhering to guidelines. This study assessed documented indications for IVC filter placement and evaluated compliance with standards set by the American College of Chest Physicians (ACCP) and the Society of Interventional Radiology (SIR). MATERIALS AND METHODS: A single-center, retrospective medical record review in a metropolitan, 652-bed, acute care, teaching hospital. Inpatient filter placement over a 26-month period was reviewed. The study measured compliance with established guidelines, relationship of medical specialty to filter placement, and evaluation of self-referral patterns among physicians. RESULTS: Compliance with established ACCP guidelines was poor regardless of whether the IVC filter insertion was performed by interventional radiology (IR; 43.5%), vascular surgery (VS; 39.9%), or interventional cardiology (IC; 33.3%) staff. Compliance with the less restrictive SIR guidelines was better (77.5%, 77.1%, and 80% for IR, VS, and IC, respectively). There was a greater degree of guideline compliance when filter placement was recommended by internal medicine (IM)-trained physicians than by non-IM-trained physicians: 46.3% of IR-placed filters requested by IM physicians met ACCP criteria whereas only 24.0% of filters recommended by non-IM specialties were compliant with criteria (P = .03). In the VS group, these compliance rates were 45.8% and 31.5%, respectively (P = .03). Among IR-placed filters, 84.0% of IM-recommended filter placements were compliant with SIR guidelines, versus only 48.0% of non-IM-recommended placements (P
PMID: 22698970
ISSN: 1051-0443
CID: 703912

Human papillomavirus incidence and clearance among HIV-positive and HIV-negative men in sub-Saharan Africa

Tobian, Aaron A R; Kigozi, Godfrey; Gravitt, Patti E; Xiao, Changchang; Serwadda, David; Eaton, Kevin P; Kong, Xiangrong; Wawer, Maria J; Nalugoda, Fred; Quinn, Thomas C; Gray, Ronald H
OBJECTIVES/OBJECTIVE:High-risk human papillomavirus (HR-HPV) infection is the most common sexually transmitted infection. Penile and cervical cancer rates are highest in sub-Saharan Africa. However, little is known about the impact of HIV infection on HR-HPV acquisition and clearance among heterosexual men. DESIGN/METHODS:HR-HPV incidence and clearance were evaluated in 999 men (776 HIV-negative and 223 HIV-positive) aged 15-49 years who participated in male circumcision trials in Rakai, Uganda. METHODS:Penile swabs were tested for HR-HPV by Roche HPV Linear Array. A Poisson multivariable model was used to estimate adjusted incidence rate ratios (adjIRRs) and clearance risk ratios (adjRRs). RESULTS:HR-HPV incidence was 66.5/100 person-years in HIV-positive men and 32.9/100 person-years among HIV-negative men [IRR=2.02, 95% confidence interval (CI) 1.67-2.44]. Incidence was higher in the unmarried men (adjIRR=1.73, 95% CI 1.19-2.52), and decreased with age (adjIRR for men >35 years=0.64, 95% CI 0.43-0.94) and male circumcision (adjIRR=0.70, 95% CI 0.55-0.89). HR-HPV clearance was 114.7/100 person-years for HIV-positive men and 170.2/100 person-years for HIV-negative men (risk ratio=0.67, 95% CI 0.59-0.77). HR-HPV clearance in HIV-negative men increased with circumcision (adjRR=1.48, 95% CI 1.26-1.74), HSV-2 infection (adjRR=1.20, 95% CI 1.01-1.44), and symptoms of urethral discharge (adjRR=1.35, 95% CI 1.06-1.73). Clearance of HR-HPV was significantly lower for unmarried men (adjRR 0.76, 95% CI 0.59-0.98). CONCLUSION/CONCLUSIONS:HR-HPV is common among heterosexual Ugandan men, particularly the HIV-infected. HIV infection increases HR-HPV acquisition and reduces HR-HPV clearance. Promotion of male circumcision and additional prevention measures, such as HPV vaccination, is critical in sub-Saharan Africa.
PMCID:3442933
PMID: 22441255
ISSN: 1473-5571
CID: 3128972

A World Without AIDS, Still Worlds Away [Newspaper Article]

Altman, Lawrence K
Among those gains: antiretroviral drug combinations for women to prevent infection of their newborns; drugs to treat and prevent infection with H.I.V., the virus that causes AIDS, among adults; and evidence that voluntary male circumcision can reduce the risk of female-to-male transmission by 50 to 60 percent. [...]defining the word "epidemic" is difficult
PROQUEST:1030174313
ISSN: 0362-4331
CID: 815382

Imagine a World Without AIDS [Newspaper Article]

Ofri, Danielle
Potent combinations of antiviral medications that brought patients off their deathbeds and back to life, viral load testing and H.I.V. genotyping that helped tailor treatment regimens, screening of the blood supply, aggressive public health campaigns, prevention of maternal-fetal transmission -- we could hardly have envisioned the pace of development. The apparent H.I.V. cure as a result of a bone-marrow transplant in a man known as the "Berlin patient" has stimulated tantalizing gene therapy research
PROQUEST:1029895257
ISSN: 0362-4331
CID: 814482

Hasty and Ruinous 1972 Pick Colors Today's Hunt for a No. 2 [Newspaper Article]

Altman, Lawrence K
Scott Lilly was a young member of Senator George McGovern's presidential campaign staff in the summer of 1972, and he remembers the satisfaction he felt when Mr. McGovern chose Mr. Lilly's home-state senator to be the Democratic Party's vice-presidential candidate
PROQUEST:1030523434
ISSN: 0362-4331
CID: 815392

Exhibition: Mensches with MDs

Ofri, Danielle
Jewish community organisations from Palestine to the Lower East Side embraced medical advancements, promoting breastfeeding, milk for young children, vaccination, and sanitation. American medical schools- shamed by the Holocaust, influenced by the civil rights movement-finally dropped their quotas and Jews again took to medicine in numbers that vastly over-represented their proportion of the population
PROQUEST:1030161323
ISSN: 0140-6736
CID: 2529562

Well [New York Times Blog], July 19, 2012

Falling Into the Diagnostic Trap

Ofri, Danielle
(Website)
CID: 2530172

Heat shock protein 27 mediated signaling in viral infection

Rajaiya, Jaya; Yousuf, Mohammad A; Singh, Gurdeep; Stanish, Heather; Chodosh, James
Heat shock proteins (HSPs) play a critical role in many intracellular processes, including apoptosis and delivery of other proteins to intracellular compartments. Small HSPs have been shown previously to participate in many cellular functions, including IL-8 induction. Human adenovirus infection activates intracellular signaling, involving particularly the c-Src and mitogen-activated protein kinases [Natarajan, K., et al. (2003) J. Immunol. 170, 6234-6243]. HSP27 and MK2 are also phosphorylated, and c-Src, and its downstream targets, p38, ERK1/2, and c-Jun-terminal kinase (JNK), differentially mediate IL-8 and MCP-1 expression. Specifically, activation and translocation of transcription factor NFκB-p65 occurs in a p38-dependent fashion [Rajaiya, J., et al. (2009) Mol. Vision 15, 2879-2889]. Herein, we report a novel role for HSP27 in an association of p38 with NFκB-p65. Immunoprecipitation assays of virus-infected but not mock-infected cells revealed a signaling complex including p38 and NFκB-p65. Transfection with HSP27 short interfering RNA (siRNA) but not scrambled RNA disrupted this association and reduced the level of IL-8 expression. Transfection with HSP27 siRNA also reduced the level of nuclear localization of NFκB-p65 and p38. By use of tagged p38 mutants, we found that amino acids 279-347 of p38 are necessary for the association of p38 with NFκB-p65. These studies strongly suggest that HSP27, p38, and NFκB-p65 form a signalosome in virus-infected cells and influence downstream expression of pro-inflammatory mediators.
PMCID:3680509
PMID: 22734719
ISSN: 1520-4995
CID: 4944562