Faculty Bibliography

Language barriers may contribute to the under-detection of depression in Latinos and Asians. A total of 782 English, Spanish, and Chinese-speaking primary care patients were enrolled in a randomized controlled trial. Language discordant patients were randomized to Remote Simultaneous Medical Interpreting (RSMI) or usual and customary (U&C) interpreting. The Beck Depression Inventory-Fast Screen (BDI-FS) was administered. Patients were tracked for 1 year. A total of 462 patients completed the BDI-FS. Thirty-three percent had a positive (>/=4) screen. Twenty-seven percent of BDI-FS positive patients were diagnosed with depression. Among BDI-FS positive patients, Chinese-speakers were less likely to be diagnosed compared with English speakers (31% vs. 10%, P < 0.05). There was a trend towards greater diagnosis with RSMI (27% detection with RSMI vs. 20% U&C, P = 0.41). The diagnosis of depression among BDI-FS positive patients in our population was low, particularly among Chinese-speakers. RSMI could be an important part of a multi-faceted approach to improving the detection of depression

Dr. [James W. Black] started out working in academia, but in 1958 he went against the academic grain by moving to a drug company. 'One thing was clear at that time: Going into industry was a no-no,' he said in an interview in Molecular Interventions, a journal published by the American Society for Pharmacology and Experimental Therapeutics in Bethesda, Maryland. 'If you were a good scientist, you didn't go into industry.' Jerry Adler, a harmonica virtuoso whose pure, open sound can be heard on the soundtracks to 'Shane,' 'High Noon,' 'Mary Poppins' and other films, but who labored in the shadow of his more famous harmonica-playing older brother, [Larry Adler], died on March 13 in Ellenton, Florida. He was 91 and lived in Sarasota. He was highly sought after as a soloist in films from the 1940s through the 1960s. His credits include the soundtracks for 'Shane,' 'High Noon,' 'The Alamo,' 'You Can't Take It With You,' 'Mary Poppins' and 'My Fair Lady.'

Not only did the drugs help relieve angina pain, they also lowered death rates. [...] beta blockers are sometimes used to treat migraine headaches and anxiety, among other conditions

Mercy [Television Program] -- The reality Dr. William L. Risser, director of adolescent medicine at the University of Texas Medical School at Houston, says he would consider hepatitis, pancreatitis or pelvic inflammatory disease as the most likely causes of such pain and vomiting in an 11-year-old

Known then as retrolental fibroplasia, it is now called retinopathy of prematurity, or R.O.P. The oxygen, he found, led to overgrowth of blood vessels in the eye, damaging the retina irreparably. After earning undergraduate and medical degrees from Emory University in Atlanta, Dr. Patz served in the ambulance corps during World War II, often transporting patients from Camp Lee, Va., to Walter Reed General Hospital in Washington

[...] Dr. Childs helped shape the understanding of inherited diseases as scientists learned more about so-called inborn errors of metabolism, biochemistry, and molecular biology.

BACKGROUND:The effect of aggressive medical therapy on quantitative coronary plaque burden is not generally known, especially in ethnic Chinese. AIMS/OBJECTIVE:We reasoned that Cardiac CT could conveniently quantify early coronary atherosclerosis in our patient population, and hypothesized that serial observation could differentiate the efficacy of aggressive medical therapy regarding progression and regression of the atherosclerotic process, as well as evaluating the additional impact of life-style modification and the relative effects of the application of statin therapy. METHODS:We employed a standardized Cardiac CT protocol to serially scan 113 westernized Hong Kong Chinese individuals (64 men and 49 women) with Chest Pain and positive coronary risk factors. In all cases included for this serial investigation, subsequent evaluation showed no significantly-obstructive coronary disease by functional studies and angiography. After stringent risk factor modification, including aggressive statin therapy to achieve LDL-cholesterol lowering conforming to N.C.E.P. ATP III guidelines, serial CT scans were performed 1-12 years apart for changes in coronary artery calcification (CAC), using the Agatston Score (AS) for quantification. RESULTS:At baseline, the mean AS was 1413.6 for males (mean age 54.4 years) and 2293.3 for females (mean age 62.4 years). The average increase of AS in the entire study population was 24% per year, contrasting with 16.4% per year on strict risk factor modification plus statin therapy, as opposed to 33.2% per year for historical control patients (p < 0.001). Additionally, 20.4% of the 113 patients demonstrated decreasing calcium scores. Medical therapy also yielded a remarkably low adverse event rate during the follow-up period --- 2 deaths, 2 strokes and only 1 case requiring PCI. CONCLUSIONS:This study revealed that aggressive medical therapy can positively influence coronary plaque aiding in serial regression of calcium scores.

[...] Dr. Childs helped shape the understanding of inherited diseases as scientists learned more about so-called inborn errors of metabolism, biochemistry and molecular biology. If a mother's gene for the Factor VIII blood clotting agent is mutated, that could be harmful to a son, leading to hemophilia, because the gene is on the X that she has supplied to the boy (with the father having supplied the Y)