Faculty Bibliography

Feeling should return to her face in six months, and most facial functions in about a year, leading to her ability to smile after physical therapy to help train the muscles for that function

Transplant pioneers say the psychological effects of facial damage from injuries, birth defects, burns and a number of diseases can be psychologically devastating. Though reconstructive surgery is possible in many cases, proponents say that in other cases, an experimental face transplant may be worth the risks if patients and donors and their families understand them. In 2006, Chinese doctors did a partial face transplant on a farmer who lost much of the right side of his face in a bear attack. In 2007, a French team performed the third partial facial transplant, on a 29-year-old man who had been disfigured by neurofibromatosis

Transplant pioneers say the psychological effects of facial damage from injuries, birth defects, burns and a number of diseases can be psychologically devastating. Though reconstructive surgery is possible in many cases, proponents say that in other cases, an experimental face transplant could be worth the risks if patients and donors and their families understand them. In November 2005, a team in Amiens, France, performed the first partial face transplant. The recipient, Isabelle Dinoire, then 38, was seriously disfigured when her Labrador retriever mauled her. In 2006, Chinese doctors did a partial face transplant on a farmer who lost much of the right side of his face in a bear attack. In 2007, a French team performed the third partial facial transplant, on a 29-year-old man. His face had been disfigured by neurofibromatosis, a genetic disorder of the nervous system that causes tumors to grow in tissues around nerves

[...] transplant pioneers say that the psychological effects of facial damage from injuries, birth defects, burns and a number of diseases can be psychologically devastating

Boston Legal [Television Program] -- Can a patient live for years like this? -- The reality 'Alzheimer's disease causes characteristic metabolic patterns of deficits which can be detected by PET scans,' says Dr. P. Murali Doraiswamy, chief of biological psychiatry at Duke University

Eli Stone [Television Program] -- Cooper wants to begin a clinical trial using medical marijuana as a cure for his son, and he is petitioning the Drug Enforcement Administration to allow him to grow his own marijuana for medical purposes (this is legal in California but not under federal law)

A 10-year-old boy with osteosarcoma and normal renal function manifested laboratory evidence of impending renal toxicity and extreme elevation of aspartate aminotrasferase and alanine aminotransferase within 2 hours after the completion of a 4-hour infusion of high-dose methotrexate (MTX) (12 g/m2), and went on to develop acute renal failure with life-threatening hyperkalemia 29 hours later. Although his renal function recovered completely with high-dose leucovorin, hemodialysis, charcoal hemoperfusion, and carboxypeptidase G2, we present this case to emphasize that signs of renal toxicity may be present as early as 2 hours after the completion of a 4-hour MTX infusion, and to suggest that monitoring for MTX toxicity should perhaps begin within a few hours after the completion of 4-hour MTX infusion.

OBJECTIVES: Workplace violence is a concerning issue. Healthcare workers represent a significant portion of the victims, especially those who work in the emergency department (ED). The objective of this study was to examine ED workplace violence and staff perceptions of physical safety. METHODS: Data were obtained from the National Emergency Department Safety Study (NEDSS), which surveyed staff across 69 U.S. EDs including physicians, residents, nurses, nurse practitioners, and physician assistants. The authors also conducted surveys of key informants (one from each site) including ED chairs, medical directors, nurse managers, and administrators. The main outcome measures included physical attacks against staff, frequency of guns or knives in the ED, and staff perceptions of physical safety. RESULTS: A total of 5,695 staff surveys were distributed, and 3,518 surveys from 65 sites were included in the final analysis. One-fourth of surveyed ED staff reported feeling safe sometimes, rarely, or never. Key informants at the sampled EDs reported a total of 3,461 physical attacks (median of 11 attacks per ED) over the 5-year period. Key informants at 20% of EDs reported that guns or knives were brought to the ED on a daily or weekly basis. In multivariate analysis, nurses were less likely to feel safe "most of the time" or "always" when compared to other surveyed staff. CONCLUSIONS: This study showed that violence and weapons in the ED are common, and nurses were less likely to feel safe than other ED staff.

Study purpose was to revise and examine the validity of the Medication Adherence Self-Efficacy Scale (MASES) in an independent sample of 168 hypertensive African Americans: mean age 54 years (SD = 12.36); 86% female; 76% high school education or greater. Participants provided demographic information; completed the MASES, self-report and electronic measures of medication adherence at baseline and three months. Confirmatory (CFA), exploratory (EFA) factor analyses, and classical test theory (CTT) analyses suggested that MASES is unidimensional and internally reliable. Item response theory (IRT) analyses led to a revised 13-item version of the scale: MASES-R. EFA, CTT, and IRT results provide a foundation of support for MASES-R reliability and validity for African Americans with hypertension. Research examining MASES-R psychometric properties in other ethnic groups will improve generalizability of findings and utility of the scale across groups. The MASES-R is brief, quick to administer, and can capture useful data on adherence self-efficacy