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Recommendations on Topical Fluoride Usage for Caries Management in East Asia

Zheng, Faith Miaomiao; Adiatman, Melissa; Chu, Chun Hung; Crystal, Yasmi O; Featherstone, John D; Hoang, Trong Hung; Kim, Baek Il; Ogawa, Hiroshi; Pitiphat, Waranuch; Kadir, Rahimah Abdul; Wong, Mun Loke; Zheng, Shuguo
Dental caries is a widespread oral health issue in Asia, affecting an estimated 30% to 90% of children and adults. Many caries cases remain untreated, resulting in pain and infection. In response, the Asian Academy of Preventive Dentistry (AAPD) emphasises comprehensive caries management and organised a fluoride workshop at the 15th International Conference of the AAPD in 2023. The AAPD invited a group of experts to form a fluoride working group to review existing literature and develop fluoride recommendations for stakeholders across Asian countries and regions. The working group assessed caries risk and identified commonly used topical fluoride products for home care, professional, and community settings in Asia. The working group concluded that fluoride is a safe and highly effective strategy to reduce caries prevalence and incidence. The working group provided key recommendations based on successful regional caries management practices: (1) use topical fluoride for prevention and control of dental caries; (2) encourage the use of fluoride toothpaste with a concentration of at least 1,000 ppm for effective caries reduction; (3) advise a 0.05% fluoride mouth rinse as soon as children can spit it out to prevent early childhood caries; (4) deliver professionally administered fluoride, such as 5% sodium fluoride varnish, 2% fluoride gel, or 1.23% acidulated phosphate fluoride preparations, to decrease dental caries in at-risk individuals; and (5) apply 38% silver diamine fluoride to arrest cavitated caries. These recommendations aim to help practitioners, health care providers, and parents/caregivers make informed decisions about fluoride use as part of comprehensive oral health care in the region.
PMID: 38871599
ISSN: 1875-595x
CID: 5669702

Effectiveness of buccal administration of dexmedetomidine and ketamine combination in paediatric dental sedation: A randomized controlled clinical trial

El-Rouby, Sara H; Crystal, Yasmi O; Elshafie, Ahmed M; Wahba, Nadia A; El-Tekeya, Magda M
BACKGROUND:Pain and anxiety can be considerable obstacles while treating paediatric dental patients. Moderate sedation is needed to treat uncooperative patients. AIM/OBJECTIVE:This study aimed to compare the effectiveness of buccal administration of dexmedetomidine-ketamine combination versus dexmedetomidine. DESIGN/METHODS:Fifty-six uncooperative children were randomly assigned into two groups: Group I received buccal dexmedetomidine (2 μg/kg) and ketamine (2 mg/kg) (DEX-KET), whereas Group II received buccal dexmedetomidine (4 μg/kg) (DEX). The effects of drugs were evaluated based on changes in vital signs, onset and duration of sedation, sedation level, analgesia, ease of treatment and procedural adverse effects. RESULTS:There were no significant differences in vital signs or sedation onset between the two groups. DEX-KET group showed shorter recovery time than DEX group (p < .0001). There were no statistically significant differences between both groups regarding sedation level at optimum sedation and during operative procedure (p = .064, p = .069 respectively). The ease of treatment was significantly better in DEX-KET group than in DEX group (p = .048). Procedural side effects and analgesic effects of the sedative drugs were comparable between both groups. CONCLUSION/CONCLUSIONS:The combination of dexmedetomidine and ketamine delivered buccally provided a better method of delivering care to uncooperative children with more rapid recovery than dexmedetomidine.
PMID: 39011758
ISSN: 1365-263x
CID: 5754692

A scoping review of the links between early childhood caries and clean water and sanitation: the Sustainable Development Goal 6

Crystal, Yasmi O; Luo, Yuanyuan Laura; Duangthip, Duangporn; Tantawi, Maha El; Benzian, Habib; Schroth, Robert J; Feldens, Carlos Alberto; Virtanen, Jorma I; Al-Batayneh, Ola B; Diaz, Aida Carolina Medina; Vukovic, Ana; Pavlic, Verica; Mfolo, Tshepiso; Daryanavard, Hamideh A; Gaffar, Balgis O; Shamala, Anas; Foláyan, Morẹ́nikẹ́ Oluwátóyìn; ,
INTRODUCTION:The United Nation's Sustainable Development Goal (SDG) 6 calls for universal access to clean water, sanitation and hygiene (WASH), which are crucial elements of health and well-being and fundamental for a life in dignity. Early childhood caries (ECC) is a preventable disease affecting health and quality of life of millions of young children worldwide. This scoping review aims to explore the connection between ECC and access to clean water and sanitation. METHODS:This scoping review, registered on the Open Science Framework and following PRISMA-ScR guidelines, conducted a thorough search in databases (PubMed, Web of Science, Embase, Google Scholar, SciELO) and websites (via Google) in November 2023. The search, without date limitations, targeted studies in English and Spanish linking ECC to SDG6. Exclusions were made for studies solely focusing on ECC without a direct connection to clean water and sanitation. Descriptive statistics summarized the retrieved papers. RESULTS:The initial search yielded 303 articles. After removing duplicates, 264 articles remained for title and abstract screening after which 244 were excluded and one report was added through citation searching. The 21 remaining articles underwent full text review. There were no studies on a direct association between access to clean water and sanitation and the prevalence of ECC. There were nine studies that showed indirect associations between ECC and access to clean water and sanitation through the links of: water and sanitation access as a marker for poverty (n = 1), water consumption as a feeding practice (n = 4), and the effectiveness of water fluoridation (n = 4). These were used to develop a conceptual model. CONCLUSIONS:While it is conceivable that a direct link exists between ECC and access to clean water and sanitation, the available body of research only offers evidence of indirect associations. The exploration of potential pathways connecting water access to ECC warrants further investigation in future research.
PMCID:11234638
PMID: 38982426
ISSN: 1472-6831
CID: 5698912

Use of Vital Pulp Therapies in Primary Teeth 2024

Coll, James A; Dhar, Vineet; Chen, Chia-Yu; Crystal, Yasmi O; Guelmann, Marcio; Marghalani, Abdullah A; AlShamali, Shahad; Xu, Zheng; Glickman, Gerald N; Wedeward, Rachel
PMID: 38449041
ISSN: 1942-5473
CID: 5756102

Enhancing patient-provider encounters when proposing SDF therapy by utilizing a qualitative analysis of parental feedback

Crystal, Yasmi O; Jang, Jenny Hiyeji; Raveis, Victoria H
PURPOSE/UNASSIGNED:Silver Diamine Fluoride (SDF) is a minimally invasive option for caries arrest, part of a paradigm shift in the management of pediatric dental caries. The perspective of parents regarding the long-term pros and cons of this therapy should be understood in order to achieve optimal patient-centered care. METHODS/UNASSIGNED:This study used Constant comparative analysis as an analytic approach, applying the Precaution-Adoption Process Model (PAPM) as the Grounded Theory framework in the qualitative analysis of 30 parental unformatted, spontaneous comments collected at the end of a questionnaire to evaluate their satisfaction with treatment provided at a University Clinic. RESULTS/UNASSIGNED:Our analysis provided important insights about the factors that influenced the parents' decision to act and have their child receive SDF therapy, their perception of the outcomes, the necessary follow-ups after the therapy, and what impacted on their overall satisfaction with the completed procedure. Both positive and negative themes were identified. The positive themes point to SDF treatment's ease of application and addressing the immediate treatment needs on children with limited cooperation. The negative themes identified the adverse consequences of SDF treatment, specifically, the duration and appearance of the cosmetic consequences, as well as the parents' misunderstandings and incorrect expectations of the long-term sustainability of the treatment, which in many instances requires further interventions. It was also evident from the parents' comments that they needed additional educational guidance on other aspects of the treatment, such as the necessity for clinical follow-ups, information that impacted parents' overall satisfaction with the treatment their child received. CONCLUSION/UNASSIGNED:Our results highlight the need to discuss the short and long term benefits of the treatment, as well as, its short and long-term limitations. Specifically, while it is important to discuss immediate outcomes and consequences, such as the ease of treatment and the resultant staining, to ensure that parental consent for the treatment is truly well-informed, it is also important to prepare parents, when this procedure is initially proposed, of the likely need for additional oral care interventions in the future.
PMCID:11446903
PMID: 39364345
ISSN: 2673-4842
CID: 5739022

Primary Tooth Vital Pulp Treatment Interventions: Systematic Review and Meta-Analyses

Coll, James A; Dhar, Vineet; Chen, Chia-Yu; Crystal, Yasmi O; Guelmann, Marcio; Marghalani, Abdullah A; AlShamali, Shahad; Xu, Zheng; Glickman, Gerald; Wedeward, Rachel
PMID: 38129755
ISSN: 1942-5473
CID: 5611792

Effects of LED curing light on silver diamine fluoride penetration into dentin

Crystal, Yasmi O; Rabieh, Sasan; Janal, Malvin N; Cerezal, Gretchen; Hu, Bin; Bromage, Timothy G
This ex-vivo study investigated the effect of a light-emitting diode (LED) curing light on the depth of penetration of Silver Diamine Fluoride (SDF) into carious lesions. Twenty-four primary teeth with untreated caries lesions were allocated into groups and treated within 5 min after extraction: (1) n = 6 treated for 1 min with one drop of SDF followed by 10 sec rinse with tap water, (2) n = 6 treated for 10 sec with one drop of SDF and exposed to LED light for 20 sec (30 sec total SDF exposure) followed by 10 sec rinse with tap water, (3) n = 6 treated for 10 sec with one drop of SDF followed by a 10 sec rinse with tap water, (4) n = 3 untreated, and (5) n = 3 untreated but exposed to LED light for 20 sec. Samples were prepared, embedded, sectioned and silver penetration was measured using backscattered electron imaging in the scanning electron microscope and energy-dispersive X-ray spectroscopy analysis. Results were expressed as the average relative depth of penetration (%) = Ag depth/lesion depth × 100 from 5 sites in each lesion. Group means were compared using mixed model analysis. Mean ± standard deviation (SD) penetration was: 86.4 ± 20.7% in Group 1, 94.3 ± 13.7% in Group 2, and 26.7 ± 13.9% in Group 3. Groups 1 and 2 were statistically similar and different from Group 3 (p < 0.001). Groups 4 and 5 had no silver present. Use of LED light for 20 sec after 10 sec SDF application appears to facilitate silver penetration, similar to a 1 min SDF application. Clinical studies are needed to define the role of silver penetration in sustained caries arrest.
PMID: 37997234
ISSN: 1053-4628
CID: 5608992

A scoping review on the association of early childhood caries and maternal gender inequality

Sun, Ivy Guofang; Duangthip, Duangporn; Kwok, Charis Hiu-Kei; Chu, Chun Hung; Crystal, Yasmi O; Schroth, Robert J; Feldens, Carlos Alberto; Virtanen, Jorma I; Al-Batayneh, Ola Barakat; Gaffar, Balgis; Mfolo, Tshepiso; El Tantawi, Maha; Mohebbi, Simin Z; Daryanavard, Hamideh; Folayan, Morenike Oluwatoyin; ,
AIM:The objective of this scoping review is to present current evidence regarding the association between early childhood caries (ECC) and maternal-related gender inequality. METHODS:Two independent reviewers performed a comprehensive literature search using three databases: EMBASE, PubMed, and Web of Science. Literature published in English from 2012 to 2022 was included in the search and was restricted to only primary research by using the following key terms: "dental caries", "tooth decay", "gender", "sex", "preschool", "toddler," and "infant". The included studies were limited to those reporting an association between ECC and maternal aspects related to gender inequality. Titles and abstracts were screened, and irrelevant publications were excluded. The full text of the remaining papers was retrieved and used to perform the review. The critical appraisal of selected studies was guided by the Joanna Briggs Institute (JBI) Critical Appraisal Tools. RESULTS:Among 1,103 studies from the three databases, 425 articles were identified based on publication years between 2012 and 2022. After full-text screening, five articles were included in the qualitative analysis for this review. No published study was found regarding a direct association between ECC and maternal gender inequality at the level of individuals. Five included studies reported on the association between ECC and potential maternal-gender-related inequality factors, including the mother's education level (n = 4), employment status (n = 1), and age (n = 1). Regarding the quality of the included studies, out of five, two studies met all JBI criteria, while three partially met the criteria. CONCLUSIONS:Based on the findings of this scoping review, evidence demonstrating an association between gender inequality and ECC is currently limited.
PMCID:10369774
PMID: 37495986
ISSN: 1472-6831
CID: 5592362

Editorial: Frontiers in oral health: Highlights in preventive dentistry 2021/2

Crystal, Yasmi O.; Campus, Guglielmo; Cunha-Cruz, Joana
SCOPUS:85146826481
ISSN: 2673-4842
CID: 5423892

Factors that influence parental satisfaction with SDF treatment in healthy children and those with special health care needs

Crystal, Y. O.; Jang, J. H.; Janal, M. N.; Raveis, V. H.
Purpose: Silver diamine fluoride (SDF) is used as a caries management agent for the arrest of dentinal caries lesions. The purpose of this study was to evaluate the satisfaction with SDF treatment provided at a university pediatric dentistry clinic, and to identify factors that may contribute to parental dissatisfaction. Methods: We obtained retrospective data of children who received SDF treatment at our clinic from February 1st, 2019 to February 28th, 2021. Parents were contacted by phone to participate in a survey that evaluated their satisfaction with the treatment. Satisfaction was evaluated as a function of medical status, ease of treatment, outcome of SDF treatment, esthetics, and understanding of the treatment's goals and side effects using contingency tables and chi-square statistics. Results: From 209 children who received SDF treatment, we were able to contact 91 parents by telephone, and 79 agreed to participate. Special healthcare needs (SHCN) patients were over represented in our sample, comprising 22.3% of all treated and 36.7% of participants. More than 90% were satisfied with the treatment, would do it again and would recommend it to others. Among the 49 children who complained of pain, SDF treatment resolved 82% of these complaints. In the subsample with follow-up in our clinic, approximately half of the treated teeth later received restorative treatment or were extracted, and the other half presented without further treatment. Some children received further treatment elsewhere. Parental dissatisfaction was related to staining of the anterior teeth (p = 0.04), the need for further treatment (p = 0.02) and a lesser understanding of side effects (p = 0.002). Conclusion: Most parents were satisfied with SDF therapy as a dental treatment choice due to its easy application and desensitizing effects. Our findings indicate that parental understanding of the interim nature of the treatment and staining of the lesions are important to achieve parental satisfaction.
SCOPUS:85178006366
ISSN: 2673-4915
CID: 5623052