Searched for: school:SOM
Department/Unit:Otolaryngology
A PHASE II, OPEN-LABEL, SINGLE ARM, MULTICENTER STUDY OF AVELUMAB WITH HYPOFRACTIONATED RE-IRRADIATION IN ADULT SUBJECTS WITH TRANSFORMED IDH MUTANT GLIOBLASTOMA [Meeting Abstract]
Chi, Andrew S; Eisele, Sylvia; Arrillaga-Romany, Isabel; Batchelor, Tracy; Cahill, Daniel; Taylor, Jennie; Cloughesy, Timothy F; Patel, Amie; Delara, Malcolm; Latchman, Sunita; Placantonakis, Dimitris; Pacione, Donato; Fatterpekar, Girish; Shepherd, Timothy; Jain, Rajan; Cordova, Christine; Schafrick, Jessica; Snuderl, Matija; Zagzag, David; Kondziolka, Douglas; Golfinos, John; Silverman, Joshua
ISI:000415152500099
ISSN: 1523-5866
CID: 2802502
MR IMAGING PHENOTYPE CORRELATES WITH EXTENT OF GENOME-WIDE COPY NUMBER ABUNDANCE IN IDH MUTATED GLIOMAS [Meeting Abstract]
Wu, Chih-Chun; Jain, Rajan; Patel, Seema; Neto, Lucidio; Zagzag, David; Placantonakis, Dimitris; Golfinos, John; Chi, Andrew S; Snuderl, Matija
ISI:000415152502232
ISSN: 1523-5866
CID: 2802402
CORRELATION BETWEEN IDH MUTATION STATUS, PATIENT SURVIVAL, AND BLOOD VOLUME ESTIMATES IN DIFFUSE GLIOMAS: A TCGA/TCIA PROJECT [Meeting Abstract]
Jain, Rajan; Poisson, Laila M; Littig, Ingrid; Neto, Lucidio; Wu, Chih-Chun; Ng, Victor; Patel, Sohil H; Snuderl, Matija; Zagzag, David; Golfinos, John; Chi, Andrew S
ISI:000415152502218
ISSN: 1523-5866
CID: 2802412
CHARACTERIZATION OF GPR133 EXPRESSION IN GLIOMA SUBTYPES [Meeting Abstract]
Kader, Michael; Frenster, Joshua; Liechty, Benjamin; Modrek, Aram; Tsirigos, Aristotelis; Golfinos, John; Eisele, Sylvia; Jain, Rajan; Shepherd, Timothy; Fatterpekar, Girish; MacNeil, Douglas; Shohdy, Nadim; Huang, Xinyan; Chi, Andrew S; Snuderl, Matija; Zagzag, David; Placantonakis, Dimitris
ISI:000415152500139
ISSN: 1523-5866
CID: 2802482
Endoscopic endonasal resection of cavernous hemangioma of the palate
Piastro, Kristina; Chen, Tiffany; Khatiwala, Roshni V.; Pinheiro-Neto, Carlos D.
ORIGINAL:0017541
ISSN: 2468-5488
CID: 5785272
H3 K27M MUTANT GLIOMAS ARE SELECTIVELY KILLED BY ONC201, A SMALL MOLECULE INHIBITOR OF DOPAMINE RECEPTOR D2 [Meeting Abstract]
Chi, Andrew S; Stafford, James M; Sen, Namita; Possemato, Richard; Placantonakis, Dimitris; Hidalgo, Eveline Teresa; Harter, David; Wisoff, Jeffrey; Golfinos, John; Arrillaga-Romany, Isabel; Batchelor, Tracy; Wen, Patrick; Wakimoto, Hiroaki; Cahill, Daniel; Allen, Joshua E; Oster, Wolfgang; Snuderl, Matija
ISI:000415152501151
ISSN: 1523-5866
CID: 2802442
Molecular Subgrouping of Pineal Tumors Reveals Distinct Classes Correlated with Clinical Parameters and Genetic Alterations [Meeting Abstract]
Pfaff, E; Snuder, M; Karajannis, MA; Chavez, L; Pfister, SM; Jones, DTW
ISI:000408978201054
ISSN: 1545-5017
CID: 2766992
GLOBAL REDUCTION IN H3K27me3, SIMILAR TO H3K27M MUTANT GLIOMAS, IS A MOLECULAR SURROGATE FOR PEDIATRIC POSTERIOR FOSSA- GROUP A EPENDYMOMAS [Meeting Abstract]
Vennneti, Sriram; Panwalkar, Pooja; Clark, Jonathan; Ramaswamy, Vijay; Hawes, Debra; Yang, Fusheng; Dunham, Christopher; Yip, Stephen; Hukin, Juliette; Sun, Yilun; Schipper, Matthew; Chavez, Lukas; Margol, Ashley; Pekmezci, Melike; Chung, Chan; Banda, Adam; Bayliss, Jill; Curry, Sarah; Santi, Mariarita; Rodriguez, Fausto; Snuderl, Matija; Karajannis, Matthias; Saratsis, Amanda; Horbinski, Craig M; Kool, Marcel; Pfister, Stefan M; Taylor, Michael; Hawkins, Cynthia; Korshunov, Andrey; Judkins, Alexander
ISI:000415152503174
ISSN: 1523-5866
CID: 2802362
Microsurgically assisted inguinal hernia repair and simultaneous male fertility procedures: Rationale, technique and outcomes
Schulster, Michael L; Cohn, Matthew R; Najari, Bobby B; Goldstein, Marc
PURPOSE: Inguinal herniorrhaphy is the most common general surgical procedure. It is associated with frequent complications such as recurrence (1.9% with mesh), post-operative hematoma (4.5%), reduced sensation (0 - 42.8%), chronic post-operative pain (5.1%), vasal injury (0.1 - 0.53%) and infection (3 - 6%)1-5. Drawing on our experience utilizing the operating microscope for varicocelectomy, vasectomy reversal and repair of iatrogenic vasal obstruction from hernia repair, we employed it for inguinal hernia repair. This paper describes the rationale, technique and outcomes of microsurgically assisted inguinal hernia repair. MATERIALS AND METHODS: 291 microsurgically assisted inguinal hernia repairs were performed on 253 men by the same urologist (MG). Simultaneous microsurgical varicocelectomy or other testicular procedures were performed in 83% of cases. All were open repairs through an inguinal incision with the vas deferens, ilioinguinal nerve, genital branch of the genitofemoral nerve and spermatic vasculature identified and preserved. Median follow up was 8.6 months, and outcomes were assessed through examination, pain reporting and pathology reports. RESULTS: Chronic postoperative pain, sensory loss, infection, hematoma, vasal injury and recurrence were assessed. The incidence of hematoma was 0.85%. No hernia recurrences, chronic postoperative pain, sensory loss, infection or vasal injury was reported. CONCLUSIONS: Using an operating microscope, complications of inguinal hernia repair such as vasal obstruction, testicular atrophy, recurrence, infection, hematoma, chronic postoperative pain and loss of sensation are minimized. Microsurgically assisted hernia repair is a promising technique, especially when employed by a urologist performing simultaneous microsurgical varicocelectomy or procedures involving spermatic cord structures or testis.
PMID: 28642060
ISSN: 1527-3792
CID: 2604462
Oral Complications at Six Months after Radiation Therapy for Head and Neck Cancer
Lalla, Rajesh V; Treister, Nathaniel; Sollecito, Thomas; Schmidt, Brian; Patton, Lauren L; Mohammadi, Kusha; Hodges, James S; Brennan, Michael T
OBJECTIVE: Examine oral complications 6 months after modern radiation therapy (RT) for head and neck cancer (HNC). METHODS: Prospective multi-center cohort study of HNC patients receiving Intensity-Modulated Radiation Therapy (IMRT) or more advanced RT. Stimulated whole salivary flow, maximal mouth opening, oral mucositis, oral pain, oral health-related quality of life (OH-QOL), and oral hygiene practices, were measured in 372 subjects pre-RT and 216 at 6 months from start of RT. RESULTS: Mean stimulated whole salivary flow declined from 1.09 ml/min to 0.47 ml/min at 6 months (p < 0.0001). Mean maximal mouth opening reduced from 45.58 mm to 42.53 mm at 6 months (p < 0.0001). 8.1% of subjects had some oral mucositis at 6 months, including 3.8% with oral ulceration. Mean overall pain score was unchanged. OH-QOL was reduced at 6 months, with changes related to dry mouth, sticky saliva, swallowing solid foods, and sense of taste (p = 0.0001). At 6 months, there was greater frequency of using dental floss and greater proportion using supplemental fluoride (p < 0.0001). CONCLUSIONS: Despite advances in RT techniques, HNC patients experience oral complications 6 months after RT, with resulting negative impacts on oral function and quality of life
PMID: 28675770
ISSN: 1601-0825
CID: 2617062