Faculty Bibliography
Searched for:
school:SOM
Department/Unit:Neurology
Total Results:
23427
3D Point Cloud Completion with Geometric-Aware Adversarial Augmentation [Meeting Abstract]
ISI:000897707604002
ISSN: 1051-4651
CID: 5440522
Impaired or invalid? Limitations of assessing performance validity using the Boston Naming Test
The Boston Naming Test (BNT) has been proposed as an embedded performance validity test (PVT), though replication is needed to provide further empirical support of its simultaneous use as a cognitive ability measure and embedded PVT. This cross-sectional study examined BNT performance in a mixed neuropsychiatric sample of 137 patients with/without cognitive impairment. Four independent criterion PVTs classified 109 (80%) as valid and 28 (20%) as invalid. BNT raw and demographically-corrected T-scores were significantly higher among the valid group with small effect sizes (ηp
PMID: 32538174
ISSN: 2327-9109
CID: 5592492
A Practical Approach to Early-Onset Parkinsonism
Early-onset parkinsonism (EO parkinsonism), defined as subjects with disease onset before the age of 40 or 50 years, can be the main clinical presentation of a variety of conditions that are important to differentiate. Although rarer than classical late-onset Parkinson's disease (PD) and not infrequently overlapping with forms of juvenile onset PD, a correct diagnosis of the specific cause of EO parkinsonism is critical for offering appropriate counseling to patients, for family and work planning, and to select the most appropriate symptomatic or etiopathogenic treatments. Clinical features, radiological and laboratory findings are crucial for guiding the differential diagnosis. Here we summarize the most important conditions associated with primary and secondary EO parkinsonism. We also proposed a practical approach based on the current literature and expert opinion to help movement disorders specialists and neurologists navigate this complex and challenging landscape.
PMID: 34569973
ISSN: 1877-718x
CID: 5152222
Higher body mass index is associated with worse hippocampal vasoreactivity to carbon dioxide
Background and objectives/UNASSIGNED:) in a group of cognitively normal middle-aged and older adults. Methods/UNASSIGNED:Our study was a retrospective analysis of prospectively collected data. Subjects were enrolled for studies assessing the role of hippocampal hemodynamics as a biomarker for AD among cognitively healthy elderly individuals (age > 50). Participants without cognitive impairment, stroke, and active substance abuse were recruited between January 2008 and November 2017 at the NYU Grossman School of Medicine, former Center for Brain Health. All subjects underwent medical, psychiatric, and neurological assessments, blood tests, and MRI examinations. To estimate CVR, we increased their carbon dioxide levels using a rebreathing protocol. Relationships between BMI and brain measures were tested using linear regression. Results/UNASSIGNED:in women (β = -0.20, unstandardized B = -0.08, 95% CI -0.13, -0.02). Discussion/UNASSIGNED:These findings lend support to the notion that obesity is a risk factor for hippocampal hemodynamic impairment and suggest targeting obesity as an important prevention strategy. Prospective studies assessing the effects of weight loss on brain hemodynamic measures and inflammation are warranted.
PMCID:9491849
PMID: 36158536
ISSN: 1663-4365
CID: 5333982
Access to investigational drugs for patients with amyotrophic lateral sclerosis in the USA [Editorial]
ISI:000833401200011
ISSN: 1474-4422
CID: 5874312
A Teleintervention Program for Multiple Sclerosis (MS) Mobility: Exercise with Transcranial Direct Current Stimulation (tDCS) [Meeting Abstract]
ISI:000894020500322
ISSN: 0028-3878
CID: 5441152
Usefulness of quantitative susceptibility mapping in ALS [Meeting Abstract]
ISI:000894020500844
ISSN: 0028-3878
CID: 5504412
Stroke. 2022:53.DOI:
Hemorrhagic Conversion Of Ischemic Stroke Is Associated With Hematoma Expansion [Meeting Abstract]
ISI:000788100600385
ISSN: 0039-2499
CID: 5243802
Editorial: Advances in Therapeutics for Hyperkinetic Movement Disorders [Editorial]
PMCID:8907508
PMID: 35280292
ISSN: 1664-2295
CID: 5190892
Perspective: Lumbar adhesive arachnoiditis (AA)/ Chronic AA (CAA) are clinical diagnoses that do not require radiographic confirmation
BACKGROUND/UNASSIGNED:Our hypothesis was that lumbar adhesive arachnoiditis (AA)/chronic lumbar AA (CAA) are clinical diagnoses that do not require radiographic confirmation. Therefore, patients with these syndromes do not necessarily have to demonstrate significant radiographic abnormalities on myelograms, MyeloCT studies, and/or MR examinations. When present, typical AA/CAA findings may include; central or peripheral nerve root/cauda equina thickening/clumping (i.e. latter empty sac sign), arachnoid cysts, soft tissue masses in the subarachnoid space, and/or failure of nerve roots to migrate ventrally on prone MR/Myelo-CT studies. METHODS/UNASSIGNED:We reviewed 3 articles and 7 clinical series that involved a total of 253 patients with AA/CAA to determine whether there was a significant correlation between these clinical syndromes, and myelographic, Myelo-CT, and/or MR imaging pathology. RESULTS/UNASSIGNED:We determined that patients with the clinical diagnoses of AA/CAA do not necessarily exhibit associated radiographic abnormalities. However, a subset of patients with AA/CAA may show the classical AA/CAA findings of; central or peripheral nerve root/cauda equina thickening/clumping (empty sac sign), arachnoid cysts, soft tissue masses in the subarachnoid space, and/or failure of nerve roots to migrate ventrally on prone MR/ Myelo-CT studies. CONCLUSION/UNASSIGNED:Patients with clinical diagnoses of AA/CAA do not necessary show associated neuroradiagnostic abnormalities on myelograms, Myelo-CT studies, or MR. Rather, the clinical syndromes of AA/CAA may exist alone without the requirement for radiolographic confirmation.
PMCID:9699873
PMID: 36447842
ISSN: 2229-5097
CID: 5383602
