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Microrobotized blasting improves the bone-to-textured implant response. A preclinical in vivo biomechanical study

Coelho, Paulo G; Gil, Luiz F; Neiva, Rodrigo; Jimbo, Ryo; Tovar, Nick; Lilin, Thomas; Bonfante, Estevam A
This study evaluated the effect of microrobotized blasting of titanium endosteal implants relative to their manually blasted counterparts. Two different implant systems were utilized presenting two different implant surfaces. Control surfaces (Manual) were fabricated by manually grit blasting the implant surfaces while experimental surfaces (Microblasted) were fabricated through a microrobotized system that provided a one pass grit blasting routine. Both surfaces were created with the same ~50microm average particle size alumina powder at ~310KPa. Surfaces were then etched with 37% HCl for 20min, washed, and packaged through standard industry procedures. The surfaces were characterized through scanning electron microscopy (SEM) and optical interferometry, and were then placed in a beagle dog radius model remaining in vivo for 3 and 6 weeks. The implant removal torque was recorded and statistical analysis evaluated implant system and surface type torque levels as a function of time in vivo. Histologic sections were qualitatively evaluated for tissue response. Electron microscopy depicted textured surfaces for both manual and microblasted surfaces. Optical interferometry showed significantly higher Sa, Sq, values for the microblasted surface and no significant difference for Sds and Sdr values between surfaces. In vivo results depicted that statistically significant gains in biomechanical fixation were obtained for both implant systems tested at 6 weeks in vivo, while only one system presented significant biomechanical gain at 3 weeks. Histologic sections showed qualitative higher amounts of new bone forming around microblasted implants relative to the manually blasted group. Microrobotized blasting resulted in higher biomechanical fixation of endosteal dental implants and should be considered as an alternative for impant surface manufacturing.
PMID: 26703231
ISSN: 1878-0180
CID: 1884442

A Critical Perspective on Mechanical Testing of Implants and Prostheses

Bonfante, E A; Coelho, P G
The degree of interplay among variables in dental implant treatment presents a challenge to randomized clinical trials attempting to answer questions in a timely, unbiased, and economically feasible fashion. Further adding complexity to the different scenarios is the varied implant designs and related bone response, area of implantation, implant bulk material, restoration, abutments and related screws, fixation mode (screwed, fixed, or a combination), and horizontal implant-abutment matching geometry. This article critically appraises the most common mechanical testing methods used to characterize the implant-prostheses complex. It attempts to provide insight into the process of construction of an informed database of clinically relevant questions regarding preclinical evaluation of implant biomechanics and failure mechanisms. The use of single load to failure, fatigue life, fatigue limit, and step-stress accelerated life testing is discussed with emphasis on their deliverables, weaknesses, and strengths. Fractographic analysis and challenges in the correlation between laboratory- and in-service-produced failures of dental ceramics, resin composites, and titanium are introduced. In addition, examples are presented of mechanical characterization studies used in our laboratory to assess some implant-supported rehabilitation variables.
PMID: 26927484
ISSN: 1544-0737
CID: 2006472

Prospective Analysis of Payment per Hour in Head and Neck Reconstruction: Fiscally Feasible or Futile?

Smith, Benjamin D; Chandler, Ashley R; Braswell, Anthony; Knobel, Denis; Andrews, Brian T; Bastidas, Nicholas; Weichman, Katie E; Moon, Victor A; Kasabian, Armen K; Tanna, Neil
BACKGROUND: The authors assess the fiscal viability of complex head and neck reconstructive surgery by evaluating its financial reimbursement in the setting of resources used. METHODS: The authors prospectively assessed provider reimbursement for consecutive patients undergoing head and neck reconstruction. Total care time was determined by adding 15 minutes to the operative time for each postoperative hospital day and each postoperative follow-up appointment within the 90-day global period. Physician reimbursement was divided by total care time hours to determine an hourly rate of reimbursement. A control group of patients undergoing carpal tunnel release was evaluated using the same methods described. RESULTS: A total of 50 patients met the inclusion criteria for study. The payer was Medicaid for nine patients (18 percent), Medicare for 19 patients (38 percent), and commercial for 22 patients (44 percent). The average provider revenue per case was $3241.01 +/- $2500.65. For all patients, the mean operative time was 10.6 +/- 3.87 hours and the mean number of postoperative hospital days was 15.1 +/- 8.06. The mean reimbursement per total care time hour was $254 +/- $199.87. Statistical analysis demonstrated difference in reimbursement per total care time hour when grouped by insurance type (p = 0.002) or flap type (p = 0.033). Of the 50 most recent patients to undergo carpal tunnel release, the average revenue per case was $785.27. CONCLUSION: Total care time analysis demonstrates that physician reimbursement is not commensurate with resources used for complex head and neck reconstructive surgery.
PMID: 26910683
ISSN: 1529-4242
CID: 2045902

Palliative Reconstruction for the Management of Incurable Head and Neck Cancer

Miglani, Amar; Patel, Viraj M; Stern, Carrie S; Weichman, Katie E; Haigentz, Missak Jr; Ow, Thomas J; Garfein, Evan S
Background Surgical management of head and neck cancer is resource intensive and physiologically demanding. In patients with incurable disease, although the indications for surgery are not well defined, palliative benefit can be significant. The goal of this investigation was to compare outcomes of patients who underwent resection and reconstruction of head and neck cancer with curative intent with those who underwent similar procedures with palliative intent. Methods A retrospective review of patients who underwent reconstruction for head and neck cancer between 2008 and 2014 was conducted. Patients were divided into curative and palliative groups. Outcomes assessed included postoperative complications and survival. Results A total of 147 patients who underwent 156 operations met inclusion criteria (27 palliative and 129 curative). In both cohorts, the most common histology was squamous cell carcinoma (SCC) and the most common primary tumor site was the oral cavity. There was no significant difference between the cohorts in the rates of systemic and reconstructive complications, postoperative hospital length of stay, 30-day mortality, and flap survival. Overall survival in palliative patients was significantly shorter compared with curative patients (median OS, 6.2 months vs. 56.1 months, respectively; p < 0.0001). Among patients undergoing palliative surgery, patients without carotid involvement and those with non-SCC were significantly more likely to have longer survival. Conclusion Surgical resection with reconstruction is possible in head and neck oncologic patients undergoing palliative treatment. Palliative patients have similar short-term outcomes when compared with patients undergoing resection for curative intent. Quality-of-life and economic implications of these approaches deserve closer scrutiny.
PMID: 26636886
ISSN: 1098-8947
CID: 2041192

Taking it back

Jerrold, Laurance
PMID: 26926031
ISSN: 1097-6752
CID: 1991772

On Track to Professorship? A Bibliometric Analysis of Early Scholarly Output

Milone, Michael T; Bernstein, Joseph
Academic productivity, demonstrated by a record of scholarly publication, is the main criterion for academic promotion. Nevertheless, there are no data on early-career productivity milestones to guide young faculty members aspiring to attain professor status. We performed a bibliometric analysis to determine the number of scholarly papers published by current professors of orthopedic surgery within 5 years after their having acquired American Board of Orthopaedic Surgery certification (termed early scholarly output). Median early scholarly output for all professors (N = 108) was 11 publications. We found medians of 5 first-author and 2 last-author publications, and 4 publications in Clinical Orthopaedics and Related Research or Journal of Bone and Joint Surgery. Median number of papers cited at least 50 times by year 5 was 2. The median number of total citations was 29.5, and median Hirsch index (h-index) was 3. Faculty who were clinical professors published fewer papers and acquired fewer citations than faculty who were promoted but did have the clinical descriptor. Professors certified after 1995 were more productive than those certified before 1990. This descriptive study provided benchmark data on early scholarly productivity of current professors of orthopedic surgery and demonstrated this benchmark has risen in more recent years.
PMID: 26991577
ISSN: 1934-3418
CID: 2051402

Survival Probability of Narrow and Standard-Diameter Implants with Different Implant-Abutment Connection Designs

Freitas, Gileade P; Hirata, Ronaldo; Bonfante, Estevam A; Tovar, Nick; Coelho, Paulo G
PURPOSE: To investigate the probability of survival of different implant-abutment connection designs in narrow versus standard-diameter implants supporting anterior crowns. MATERIALS AND METHODS: A total of 108 implants of either 3.5-mm or 4.0-mm diameter (narrow and standard, respectively) (10 mm in length, Implacil de Bortoli) were divided into six groups (n = 18 each) as follows: external hexagon 3.5 mm or 4.0 mm (EH3.5 or EH4.0), internal hexagon 3.5 mm or 4.0 mm (IH3.5 or IH4.0), and Morse taper 3.5 mm or 4.0 mm (MT3.5 or MT4.0). The corresponding abutments were screwed to the implants, and standardized maxillary central incisor metal crowns were cemented and subjected to step-stress accelerated life testing in water. Use-level probability Weibull curves and reliability for a mission of 50,000 and 100,000 cycles at 100 N and 150 N (90% 2-sided confidence intervals [CI]) were calculated. Polarized-light and scanning electron microscopes were used to assess the failure modes. RESULTS: The calculated reliability with 90% CI for a mission of 50,000 cycles at 100 N and 150 N showed that cumulative damage from the respective loads would lead to ~93% and ~18% implant-supported restoration survival in group EH3.5, ~99% and ~1% in group IH3.5, ~97% and ~89% in the MT3.5, ~100% and ~99% in the group EH4.0, ~100% and ~100% in group IH4.0, and ~99% and ~99% in group MT4.0. For the 100,000-cycle mission, the probability of survival estimated at 100 N and 150 N was, respectively: 0% for EH3.5 and IH3.5 at both load levels, ~96% and ~87% for the MT3.5, 100% and ~99% for EH4.0, 100% and ~99% for IH4.0, and 98% and ~92% for the MT4.0. CONCLUSION: A significant decrease in the probability of survival as a function of elapsed fatigue cycles and load increase was observed for narrow implants only with EH and IH implant-abutment connections, but not on Morse taper.
PMID: 26929961
ISSN: 0893-2174
CID: 2046212

Online Patient Resources for Liposuction: A Comparative Analysis of Readability

Vargas, Christina R; Ricci, Joseph A; Chuang, Danielle J; Lee, Bernard T
BACKGROUND: As patients strive to become informed about health care, inadequate functional health literacy is a significant barrier. Nearly half of American adults have poor or marginal health literacy skills and the National Institutes of Health and American Medical Association have recommended that patient information should be written at a sixth grade level. The aim of this study is to identify the most commonly used online patient information about liposuction and to evaluate its readability relative to average American literacy. METHODS: An internet search of "liposuction" was performed and the 10 most popular websites identified. User and location data were disabled and sponsored results excluded. All relevant, patient-directed articles were downloaded and formatted into plain text. Articles were then analyzed using 10 established readability tests. A comparison group was constructed to identify the most popular online consumer information about tattooing. Mean readability scores and specific article characteristics were compared. RESULTS: A total of 80 articles were collected from websites about liposuction. Readability analysis revealed an overall 13.6 grade reading level (range, 10-16 grade); all articles exceeded the target sixth grade level. Consumer websites about tattooing were significantly easier to read, with a mean 7.8 grade level. These sites contained significantly fewer characters per word and words per sentence, as well as a smaller proportion of complex, long, and unfamiliar words. CONCLUSIONS: Online patient resources about liposuction are potentially too difficult for a large number of Americans to understand. Liposuction websites are significantly harder to read than consumer websites about tattooing. Aesthetic surgeons are advised to discuss with patients resources they use and guide patients to appropriate information for their skill level.
PMID: 25695442
ISSN: 1536-3708
CID: 2697762

Authors' response [Letter]

Jerrold, Laurance; Abdelkarim, Ahmad
PMID: 26926015
ISSN: 1097-6752
CID: 1991782

Commentary on: Treatment of Prominent Ears with an Implantable Clip System: A Pilot Study

Thorne, Charles H
PMCID:5127472
PMID: 26879300
ISSN: 1527-330x
CID: 1948822