Searched for: school:SOM
Department/Unit:Otolaryngology
MIDBRAIN GLIOMAS: A LARGE SERIES OF CLINICALLY AND RADIOGRAPHICALLY HETEROGENEOUS TUMORS [Meeting Abstract]
Segal, Devorah; Rao, Harini; Thomas, Cheddhi; Cohen, Benjamin; Snuderl, Matija; Karajannis, Matthias; Allen, Jeffrey
ISI:000379749000370
ISSN: 1522-8517
CID: 2964232
Generate Synthetic CT From Cone Beam CT for CBCT-Based Dose Calculation [Meeting Abstract]
Wang, H.; Barbee, D.; Wang, W.; Pennell, R.; Hu, K.; Osterman, K.
ISI:000401965400032
ISSN: 0094-2405
CID: 3589512
A PHASE 1 TRIAL OF LENALIDOMIDE PLUS RADIOTHERAPY IN CHILDREN WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMAS OR HIGH-GRADE GLIOMAS [Meeting Abstract]
Hipp, Sean; Goldman, Stewart; Kaushal, Aradhana; Glod, John; Shih, Joanna; Garvin, James; Karajannis, Matthias; Atlas, Mark; Camphausen, Kevin; Packer, Roger; Warren, Kathy
ISI:000379749000105
ISSN: 1522-8517
CID: 2964202
SUBGROUP-SPECIFIC OUTCOMES OF CHILDREN WITH MALIGNANT CHILDHOOD BRAIN TUMORS TREATED WITH AN IRRADIATION-SPARING PROTOCOL [Meeting Abstract]
Hidalgo, Eveline Teresa; Gardner, Sharon L.; Kvint, Svetlana; Wang, Shiyang; Thomas, Cheddhi; Liechty, Benjamin; Phillips, Sophie; Serrano, Jonathan; Jones, David T. W.; Hovestadt, Volker; Pfister, Stefan M.; Allen, Jeffrey C.; Wisoff, Jeffrey H.; Snuderl, Matija; Karajannis, Matthias A.
ISI:000379749000695
ISSN: 1522-8517
CID: 2964192
SAFETY AND FEASIBILITY OF A MULTI-INSTITUTIONAL PHASE II TRIAL INCOPORATING BIOPSY AND MOLECULARLY DETERMINED TREATMENT OF CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG) [Meeting Abstract]
Wright, Karen D.; Bandopadhayay, Pratiti; Gourmnerova, Liliana; Chi, Susan N.; Manley, Peter; Marcus, Karen; Kannan, Geoffrey; Banerjee, Anu; Becher, Oren; Bendel, Anne; Bowers, Daniel; Bredlau, Amy-Lee; Cohen, Kenneth; Comito, Melani; Elster, Jennifer D.; Etzl, Michael; Fisher, Paul G.; Gardner, Sharon; Goldman, Stewart; Gururangan, Sridharan; Handler, Michael H.; Jabado, Nada; Karajannis, Matthias; Khatib, Ziad; Leary, Sarah E.; MacDonald, Tobey J.; Monje, Michelle; Nazemi, Kellie; Robison, Nathan J.; Rubin, Joshua; Sandler, Eric S.; Snuderl, Matija; Wang, Zhihong Joanne; Sinai, Claire E.; Greenspan, Lianne; Lawler, Kristen; Neuberg, Donna; Filbin, Mariella; Segal, Rosalind; Suva, Mario L.; Beroukhim, Rameen; Ligon, Keith; Gupta, Nalin; Prados, Michael; Kieran, Markw.
ISI:000379749000248
ISSN: 1522-8517
CID: 2964252
Exome Sequencing Reveals Activation of STAT3 Pathway in non-VHL Tumors in Hemangioblastoma [Meeting Abstract]
Kannan, Kasthuri; Snuderl, Matija; Mashiach, Elad; Baitalmal, Rabaa; Aminova, Olga; Zappile, Paul; Karajannis, Matthias; Heguy, Adriana; Zagzag, David
ISI:000377665000041
ISSN: 0022-3069
CID: 2687532
Hyalinizing Clear Cell Carcinoma with Biopsy-Proven Spinal Metastasis: Case Report and Review of Literature [Case Report]
Newman, William C; Williams, Lindsay; Duvvuri, Umamaheswar; Clump, David A; Amankulor, Nduka
BACKGROUND:Hyalinizing clear cell carcinoma (HCCC) is a rare epithelial malignant neoplasm typically arising from the minor salivary glands. Although it has been described as a benign neoplasm, there are increasing reports of malignant features and metastases to the lungs; we present the first case of biopsy-proven spinal metastases from HCCC and an overview of the literature. CASE DESCRIPTION/METHODS:This is a single-patient case report in which we used immunohistochemistry and fluorescence in situ hybridization for Ewing sarcoma breakpoint region 1 translocation to confirm the diagnosis of HCCC in a spinal metastasis. The diagnosis of metastatic HCCC was confirmed on the basis of histopathology, immunohistochemistry, and fluorescence in situ hybridization studies. CONCLUSIONS:We present the first pathologically confirmed case of a spinal metastasis in HCCC. As increasing of metastatic HCCC arise, a reconsideration of HCCC as a potentially high-grade disease seems increasingly necessary as it may impact the current treatment paradigm.
PMID: 26862022
ISSN: 1878-8769
CID: 5481612
Temporal Malignant Solitary Fibrous Tumor
Kamrava, Brandon; Mukherjee, Abir; Weaver, Michael; Roehm, Pamela C
PMID: 26927758
ISSN: 1537-4505
CID: 2046182
Revisiting the argument for 1- versus 2-vein outflow in head and neck free tissue transfers: A review of 317 microvascular reconstructions
Silverman, Dustin A; Przylecki, Wojciech H; Arganbright, Jill M; Shnayder, Yelizaveta; Kakarala, Kiran; Nazir, Niaman; Tsue, Terance T; Girod, Douglas A; Andrews, Brian T
BACKGROUND: The purpose of this study was to determine the benefit of 1-vein versus 2-vein outflow in microvascular free tissue transfers. METHODS: A retrospective review reflects the experience of 6 surgeons. Analysis included all patients who underwent reconstruction at a single institution between January 2004 and December 2012. RESULTS: Three hundred nine patients underwent a total of 317 microvascular free flap reconstructions for head and neck defects. Two hundred thirteen of 317 flaps (67.2%) used 1 venous anastomosis and 104 (32.8%) used 2 venous anastomoses. Venous congestion necessitated urgent take back in 37 of 57 patients (64.9%) requiring exploration for perioperative complications. Thirty of 37 flaps (81.1%) with venous congestion had 1 vein anastomosis, whereas 7 (18.9%) had dual vein outflow (p = .03). Overall flap success was 303 of 317 (95.6%), despite an 18.0% (57 of 317) perioperative take back rate. CONCLUSION: Coapting 2 veins was shown to minimize venous congestion. (c) 2015 Wiley Periodicals, Inc. Head Neck 38: 820-823, 2016.
PMID: 25546076
ISSN: 1097-0347
CID: 2541482
Expanding the Utilization of the Osteocutaneous Radial Forearm Free Flap beyond Mandibular Reconstruction
Silverman, Dustin A; Przylecki, Wojciech H; Shnayder, Yelizaveta; Tsue, Terance T; Girod, Douglas A; Andrews, Brian T
Background The osteocutaneous radial forearm free flap (OCRFFF) for mandibular reconstruction has been well described. Despite this flap's utility in the repair of such defects, the indications for the OCRFFF have continued to expand in recent years. The advantages of the OCRFFF allow for a high degree of versatility in the reconstruction of the various anatomical and aesthetic units of the head and neck. In this review, the authors aim to explore the successful utilization of the OCRFFF beyond the reconstruction of composite mandibular defects. Methods A retrospective chart review was performed. All subjects who underwent OCRFFF reconstruction at a tertiary academic center between January 2004 and December 2014 were identified. A total of six patients undergoing this procedure for indications other than composite mandibular defects of the head and neck were included. Results A total of six patients underwent OCRFFF reconstruction for correction of nonmandibular defects. Flap success was experienced in six of six cases (100%). Indications included midface maxillary reconstruction (N = 2), orbit reconstruction (N = 1), frontal sinus and forehead reconstruction (N = 2), and subglottic stenosis reconstruction (N = 1). There were no immediate perioperative complications. On long-term follow-up, one subject developed a nasocutaneous fistula following radiation and eventually required maxillary hardware removal. Conclusion As a result of its growing role and versatility, the OCRFFF should be incorporated as a multipurpose tool in the armamentarium of reconstructive microvascular surgeons in the repair of composite head and neck defects beyond the mandible.
PMID: 26848567
ISSN: 1098-8947
CID: 2541392