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Utilization and Staff Perspectives on an On-Demand Telemedicine Model for People with Intellectual and Developmental Disabilities Who Reside in Certified Group Residences

Berry, Carolyn A; Kwok, Lorraine; Gofine, Miriam; Kaufman, Matthew; Williams, Debra A; Terlizzi, Kelly; Alvaro, Mike; Neighbors, Charles J
BACKGROUND/UNASSIGNED:Non-emergent medical problems that arise when a usual provider is unavailable can often result in emergency department or urgent care visits, which can be particularly distressing to people with intellectual and developmental disabilities (PIDD). On-demand, synchronous telemedicine may be a promising supplement when immediate care from usual sources is unavailable. Prior research demonstrated that high-quality telemedicine can be effectively delivered to PIDD. The aim of this article is to describe the utilization and staff perspectives on the implementation of the Telemedicine Triage Project (TTP), an innovative model that provides telemedicine consultations for PIDD who reside in state-certified group residences and present with an urgent but non-emergent medical concern when their usual provider is unavailable. METHODS/UNASSIGNED:Call frequency data for calendar years 2020 and 2021 were reviewed. The study team conducted semi-structured interviews, with 19 key informants representing organizational- and agency-level leadership and staff. The interview data were analyzed using a protocol-driven, rapid qualitative methodology. RESULTS/UNASSIGNED:Telemedicine consultations increased from 7953 in 2020 to 15,011 calls in 2021, and call volume peaked between 10 am and 1 pm. Key informants reported high satisfaction with TTP; universal benefits and a few barriers to implementation; and strong interest in maintaining the program beyond the grant period. DISCUSSION/UNASSIGNED:Over the first 2 years of its implementation, the TTP program was widely utilized and proved extremely feasible and acceptable to staff. This model is a promising and highly feasible way to provide equitable access to telemedicine for PIDD by addressing barriers to and disparities in access to health care that affect PIDD.
PMCID:10389255
PMID: 37529771
ISSN: 2692-4366
CID: 5734922

Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

de las Fuentes, Lisa; Schwander, Karen L; Brown, Michael R; Bentley, Amy R; Winkler, Thomas W; Sung, Yun Ju; Munroe, Patricia B; Miller, Clint L; Aschard, Hugo; Aslibekyan, Stella; Bartz, Traci M; Bielak, Lawrence F; Chai, Jin Fang; Cheng, Ching-Yu; Dorajoo, Rajkumar; Feitosa, Mary F; Guo, Xiuqing; Hartwig, Fernando P; Horimoto, Andrea; Kolčić, Ivana; Lim, Elise; Liu, Yongmei; Manning, Alisa K; Marten, Jonathan; Musani, Solomon K; Noordam, Raymond; Padmanabhan, Sandosh; Rankinen, Tuomo; Richard, Melissa A; Ridker, Paul M; Smith, Albert V; Vojinovic, Dina; Zonderman, Alan B; Alver, Maris; Boissel, Mathilde; Christensen, Kaare; Freedman, Barry I; Gao, Chuan; Giulianini, Franco; Harris, Sarah E; He, Meian; Hsu, Fang-Chi; Kühnel, Brigitte; Laguzzi, Federica; Li, Xiaoyin; Lyytikäinen, Leo-Pekka; Nolte, Ilja M; Poveda, Alaitz; Rauramaa, Rainer; Riaz, Muhammad; Robino, Antonietta; Sofer, Tamar; Takeuchi, Fumihiko; Tayo, Bamidele O; van der Most, Peter J; Verweij, Niek; Ware, Erin B; Weiss, Stefan; Wen, Wanqing; Yanek, Lisa R; Zhan, Yiqiang; Amin, Najaf; Arking, Dan E; Ballantyne, Christie; Boerwinkle, Eric; Brody, Jennifer A; Broeckel, Ulrich; Campbell, Archie; Canouil, Mickaël; Chai, Xiaoran; Chen, Yii-Der Ida; Chen, Xu; Chitrala, Kumaraswamy Naidu; Concas, Maria Pina; de Faire, Ulf; de Mutsert, Renée; de Silva, H Janaka; de Vries, Paul S; Do, Ahn; Faul, Jessica D; Fisher, Virginia; Floyd, James S; Forrester, Terrence; Friedlander, Yechiel; Girotto, Giorgia; Gu, C Charles; Hallmans, Göran; Heikkinen, Sami; Heng, Chew-Kiat; Homuth, Georg; Hunt, Steven; Ikram, M Arfan; Jacobs, David R; Kavousi, Maryam; Khor, Chiea Chuen; Kilpeläinen, Tuomas O; Koh, Woon-Puay; Komulainen, Pirjo; Langefeld, Carl D; Liang, Jingjing; Liu, Kiang; Liu, Jianjun; Lohman, Kurt; Mägi, Reedik; Manichaikul, Ani W; McKenzie, Colin A; Meitinger, Thomas; Milaneschi, Yuri; Nauck, Matthias; Nelson, Christopher P; O'Connell, Jeffrey R; Palmer, Nicholette D; Pereira, Alexandre C; Perls, Thomas; Peters, Annette; Polašek, Ozren; Raitakari, Olli T; Rice, Kenneth; Rice, Treva K; Rich, Stephen S; Sabanayagam, Charumathi; Schreiner, Pamela J; Shu, Xiao-Ou; Sidney, Stephen; Sims, Mario; Smith, Jennifer A; Starr, John M; Strauch, Konstantin; Tai, E Shyong; Taylor, Kent D; Tsai, Michael Y; Uitterlinden, André G; van Heemst, Diana; Waldenberger, Melanie; Wang, Ya-Xing; Wei, Wen-Bin; Wilson, Gregory; Xuan, Deng; Yao, Jie; Yu, Caizheng; Yuan, Jian-Min; Zhao, Wei; Becker, Diane M; Bonnefond, Amélie; Bowden, Donald W; Cooper, Richard S; Deary, Ian J; Divers, Jasmin; Esko, Tõnu; Franks, Paul W; Froguel, Philippe; Gieger, Christian; Jonas, Jost B; Kato, Norihiro; Lakka, Timo A; Leander, Karin; Lehtimäki, Terho; Magnusson, Patrik K E; North, Kari E; Ntalla, Ioanna; Penninx, Brenda; Samani, Nilesh J; Snieder, Harold; Spedicati, Beatrice; van der Harst, Pim; Völzke, Henry; Wagenknecht, Lynne E; Weir, David R; Wojczynski, Mary K; Wu, Tangchun; Zheng, Wei; Zhu, Xiaofeng; Bouchard, Claude; Chasman, Daniel I; Evans, Michele K; Fox, Ervin R; Gudnason, Vilmundur; Hayward, Caroline; Horta, Bernardo L; Kardia, Sharon L R; Krieger, Jose Eduardo; Mook-Kanamori, Dennis O; Peyser, Patricia A; Province, Michael M; Psaty, Bruce M; Rudan, Igor; Sim, Xueling; Smith, Blair H; van Dam, Rob M; van Duijn, Cornelia M; Wong, Tien Yin; Arnett, Donna K; Rao, Dabeeru C; Gauderman, James; Liu, Ching-Ti; Morrison, Alanna C; Rotter, Jerome I; Fornage, Myriam
PMCID:10651736
PMID: 38028628
ISSN: 1664-8021
CID: 5738322

Headache clinicians' perspectives on the remote monitoring of patients' electronic diary data: A qualitative study

Minen, Mia T; George, Alexis; Katara, Aarti; Lebowitz, Naomi; Snyder, Ivy Charlotte; Busis, Neil A; Lipchitz, Jessica M
OBJECTIVE:We assessed headache clinicians' viewpoints on potential remote access to patients' digital headache diary data and the practicalities of data utilization. BACKGROUND:With the ubiquitous nature of electronic medical records and the existence of remote monitoring (RM) for many medical conditions, there is now the potential for remote symptom monitoring for patients with headache disorders. While patients are asked to utilize headache diaries, clinicians may or may not have access to the data before patient visits, and their perspectives regarding this emerging technology are currently unknown. METHODS:After recruiting participants from the National Institutes of Health Pain Consortium Network, the American Headache Society Special Interest Section listservs, and Twitter and Facebook social media platforms, we conducted 20 semi-structured qualitative interviews of headache providers across the United States from various types of institutions and asked them their perspectives on remote access to patient headache diary data. We transcribed the interviews, which were then coded by two independent coders. Themes and sub-themes were developed using inductive content analysis. RESULTS:All clinicians felt the RM data needed to be integrated into the electronic medical record. Six themes emerged from the interviews: (i) Clinician perspectives on how RM could be beneficial but at other times could create obstacles/challenges, (ii) operationally, data integration could benefit headache care, (iii) there should be initial logistical considerations for bringing RM into clinical care, (iv) education may need to be provided to both patients and clinicians, (v) there are likely research benefits associated with RM, and (vi) additional suggestions for considering potential integration of RM into practice. CONCLUSIONS:While headache clinicians had mixed opinions on the benefits/challenges that RM presents to patient care, patient satisfaction, and visit time, new ideas emerged that may help advance the field.
PMID: 37313636
ISSN: 1526-4610
CID: 5506912

Understanding depression treatment and perinatal service preferences of Kenyan pregnant adolescents: A discrete choice experiment

Kumar, Manasi; Tele, Albert; Kathono, Joseph; Nyongesa, Vincent; Yator, Obadia; Mwaniga, Shillah; Huang, Keng Yen; McKay, Mary; Lai, Joanna; Levy, Marcy; Cuijpers, Pim; Quaife, Matthew; Unutzer, Jurgen
BACKGROUND:Understanding mental health treatment preferences of adolescents and youth is particularly important for interventions to be acceptable and successful. Person-centered care mandates empowering individuals to take charge of their own health rather than being passive recipients of services. METHODS:We conducted a discrete choice experiment to quantitatively measure adolescent treatment preferences for different care characteristics and explore tradeoffs between these. A total of 153 pregnant adolescents were recruited from two primary healthcare facilities in the informal urban settlement of Nairobi. We selected eight attributes of depression treatment option models drawn from literature review and previous qualitative work. Bayesian d-efficient design was used to identify main effects. A total of ten choice tasks were solicited per respondent. We evaluated mean preferences using mixed logit models to adjust for within subject correlation and account for unobserved heterogeneity. RESULTS:Respondents showed a positive preference that caregivers be provided with information sheets, as opposed to co-participation with caregivers. With regards to treatment options, the respondents showed a positive preference for 8 sessions as compared to 4 sessions. With regards to intervention delivery agents, the respondents had a positive preference for facility nurses as compared to community health volunteers. In terms of support, the respondents showed positive preference for parenting skills as compared to peer support. Our respondents expressed negative preferences of ANC service combined with older mothers as compared to adolescent friendly services and of being offered refreshments alone. A positive preference was revealed for combined refreshments and travel allowance over travel allowance or refreshments alone. A number of these suggestions were about enhancing their experience of maternity clinical care experience. CONCLUSION/CONCLUSIONS:This study highlights unique needs of this population. Pregnant adolescents' value responsive maternity and depression care services offered by nurses. Participants shared preference for longer psychotherapy sessions and their preference was to have adolescent centered maternal mental health and child health services within primary care.
PMCID:9994687
PMID: 36888596
ISSN: 1932-6203
CID: 5432752

Associations of SARS-CoV-2 antibodies with birth outcomes: Results from three urban birth cohorts in the NIH environmental influences on child health outcomes program

Trasande, Leonardo; Comstock, Sarah S; Herbstman, Julie B; Margolis, Amy; Alcedo, Garry; Afanasyeva, Yelena; Yu, Keunhyung; Lee, William; Lawrence, David A; ,
Studies suggest perinatal infection with SARS-CoV-2 can induce adverse birth outcomes, but studies published to date have substantial limitations. We therefore conducted an observational study of 211 births occurring between January 2020-September 2021 in three urban cohorts participating in the Environmental Influences on Child Health Outcomes Program. Serology was assessed for IgG, IgM and IgA antibodies to nucleocapsid, S1 spike, S2 spike, and receptor-binding domain. There were no differences in gestational age (GA), birth weight, preterm birth (PTB) or low birth weight (LBW) among seropositive mothers. However, the few (n = 9) IgM seropositive mothers had children with lower BW (434g, 95% CI: 116-752), BW Z score-for-GA (0.73 SD, 95% CI 0.10-1.36) and were more likely to deliver preterm (OR 8.75, 95% CI 1.22-62.4). Though there are limits to interpretation, the data support efforts to prevent SARS-CoV-2 infections in pregnancy.
PMCID:10664934
PMID: 37992059
ISSN: 1932-6203
CID: 5608632

A Phase II Trial Evaluating Rapid Mid-Treatment Nodal Shrinkage to Select for Adaptive Deescalation in p16+Oropharyngeal Cancer Patients Undergoing Definitive Chemoradiation [Meeting Abstract]

Kim, J. K.; Tam, M.; Karp, J. M.; Oh, C.; Kim, G.; Solomon, E.; Concert, C. M.; Vaezi, A. E.; Li, Z.; Tran, T.; Zan, E.; Corby, P.; Feron-Rigodon, M.; Fitz, C. Del Vecchio; Goldberg, J. D.; Hochman, T.; Givi, B.; Jacobson, A.; Persky, M.; Hu, K. S.
ISI:001079706803134
ISSN: 0360-3016
CID: 5591182

The impact of racially-targeted food marketing and attentional biases on consumption in Black adolescent females with and without obesity: Pilot data from the Black Adolescent & Entertainment (BAE) study

Cassidy, Omni; Tanofsky-Kraff, Marian; Waters, Andrew J; Shank, Lisa M; Pine, Abigail; Quattlebaum, Mary; DeLeon, Patrick H; Bragg, Marie; Sbrocco, Tracy
Unhealthy food advertisements ("advertisements" hereafter referred to as "ads") are linked to poor diet and obesity, and food companies disproportionally target Black youth. Little is known about the mechanisms whereby food ads influence diet. One possibility may be racially-targeted ads that appeal to Black youth. Those with food-related attentional biases may be especially vulnerable. The objective of this project was to assess the feasibility and initial effects of a pilot study testing the influence of racially-targeted food ads and food-related attentional biases on eating behaviors among a sample of Black adolescent females. Feasibility of recruitment, retention, and procedures were examined. Participants (N = 41, 12-17y) were randomized to view a television episode clip of the Big Bang Theory embedded with either four 30-second racially-targeted food ads or neutral ads. A computer dot probe task assessed food-related attentional biases. The primary outcome was caloric consumption from a laboratory test meal. Interactions based on weight and ethnic identity were also examined. Analyses of variance and regressions were used to assess main and interaction effects. Exposure to racially-targeted food ads (versus neutral ads) did not affect energy consumption (p > .99). Although not statistically significant, adolescents with obesity consumed nearly 240 kcal more than non-overweight adolescents (p = 0.10). There were no significant preliminary effects related to food-related attentional biases or ethnic identity (ps = 0.22-0.79). Despite a non-significant interaction, these data provide preliminary support that adolescents with obesity may be particularly vulnerable to racially-targeted food ads. An adequately powered trial is necessary to further elucidate the associations among racially-targeted food ads among Black adolescent girls with obesity.
PMCID:9858861
PMID: 36662840
ISSN: 1932-6203
CID: 5419292

Pod-based e-cigarette use among US college-aged adults: A survey on the perception of health effects, sociodemographic correlates, and interplay with other tobacco products

Obisesan, Olufunmilayo H; Uddin, S M Iftekhar; Boakye, Ellen; Osei, Albert D; Mirbolouk, Mohammadhassan; Orimoloye, Olusola A; Dzaye, Omar; El Shahawy, Omar; Stokes, Andrew; DeFilippis, Andrew P; Benjamin, Emelia J; Blaha, Michael J
INTRODUCTION/BACKGROUND:E-cigarette use among youth and young adults remains of public health concern. Pod-based e-cigarettes, including JUUL, significantly changed the e-cigarette landscape in the US. Using an online survey, we explored the socio-behavioral correlates, predisposing factors, and addictive behaviors, among young adult pod-mod users within a University in Maryland, USA. METHODS:In total, 112 eligible college students aged 18-24 years, recruited from a University in Maryland, who reported using pod-mods were included in this study. Participants were categorized into current/non-current users based on past-30-day use. Descriptive statistics were used to analyze participants' responses. RESULTS:The mean age of the survey participants was 20.5 ± 1.2 years, 56.3% were female, 48.2% White, and 40.2% reported past-30-day (current) use of pod-mods. The mean age of first experimentation with pod-mods was 17.8 ± 1.4 years, while the mean age of regular use was 18.5 ± 1.4 years, with the majority (67.9%) citing social influence as the reason for initiation. Of the current users, 62.2% owned their own devices, and 82.2% predominantly used JUUL and menthol flavor (37.8%). A significant proportion of current users (73.3%) reported buying pods in person, 45.5% of whom were aged <21 years. Among all participants, 67% had had a past serious quit attempt. Among them, 89.3% neither used nicotine replacement therapy nor prescription medications. Finally, current use (adjusted odds ratio, AOR=4.52; 95% CI: 1.76-11.64), JUUL use (AOR=2.56; 95% CI: 1.08-6.03), and menthol flavor (AOR=6.52; 95% CI: 1.38-30.89) were associated with reduced nicotine autonomy, a measure of addiction. CONCLUSIONS:Our findings provide specific data to inform the development of public health interventions targeted at college youth, including the need for more robust cessation support for pod-mod users.
PMCID:9983309
PMID: 36875734
ISSN: 1617-9625
CID: 5740462

Changes in Breast Cancer Presentation during COVID-19: Experience in an Urban Academic Center

Diskin, Brian; Pourkey, Nakisa; Schnabel, Freya; Miah, Pabel; DiMaggio, Charles; Axelrod, Deborah; Shapiro, Richard; Guth, Amber A
The COVID-19 pandemic strained healthcare systems worldwide, delaying breast cancer screening and surgery. In 2019, approximately 80% of breast cancers in the U.S. were diagnosed on screening examinations, with 76.4% of eligible Medicare patients undergoing screening at least every two years. Since the start of the pandemic, many women have been reluctant to seek elective screening mammography, even with the lifting of pandemic-related restrictions in access to routine healthcare. We describe the effect of the COVID-19 pandemic on breast cancer presentation at a tertiary academic medical center greatly impacted by the pandemic.
PMCID:10275681
PMID: 37334101
ISSN: 2090-3170
CID: 5542532

Investigating the association of traditional and non-traditional tobacco product use with subclinical and clinical cardiovascular disease: The Cross-Cohort Collaboration-Tobacco working group rationale, design, and methodology

Tasdighi, Erfan; Jha, Kunal K; Dardari, Zeina A; Osuji, Ngozi; Rajan, Tanuja; Boakye, Ellen; Hall, Michael E; Rodriguez, Carlos J; Stokes, Andrew C; El Shahawy, Omar; Benjamin, Emelia J; Bhatnagar, Aruni; DeFilippis, Andrew P; Blaha, Michael J
While the impact of combustible cigarette smoking on cardiovascular disease (CVD) is well-established, the longitudinal association of non-traditional tobacco products with subclinical and clinical CVD has not been fully explored due to: 1) limited data availability; and 2) the lack of well-phenotyped prospective cohorts. Therefore, there is the need for sufficiently powered well-phenotyped datasets to fully elucidate the CVD risks associated with non-cigarette tobacco products. The Cross-Cohort Collaboration (CCC)-Tobacco is a harmonized dataset of 23 prospective cohort studies predominantly in the US. A priori defined variables collected from each cohort included baseline characteristics, details of traditional and non-traditional tobacco product use, inflammatory markers, and outcomes including subclinical and clinical CVD. The definitions of the variables in each cohort were systematically evaluated by a team of two physician-scientists and a biostatistician. Herein, we describe the method of data acquisition and harmonization and the baseline sociodemographic and risk profile of participants in the combined CCC-Tobacco dataset. The total number of participants in the pooled cohort is 322782 (mean age: 59.7 ± 11.8 years) of which 76% are women. White individuals make up the majority (73.1%), although there is good representation of other race and ethnicity groups including African American (15.6%) and Hispanic/Latino individuals (6.4%). The prevalence of participants who never smoked, formerly smoked, and currently smoke combustible cigarettes is 50%, 36%, and 14%, respectively. The prevalence of current and former cigar, pipe, and smokeless tobacco is 7.3%, 6.4%, and 8.6%, respectively. E-cigarette use was measured only in follow-up visits of select studies, totaling 1704 former and current users. CCC-Tobacco is a large, pooled cohort dataset that is uniquely designed with increased power to expand knowledge regarding the association of traditional and non-traditional tobacco use with subclinical and clinical CVD, with extension to understudied groups including women and individuals from underrepresented racial-ethnic groups.
PMCID:10326890
PMID: 37427074
ISSN: 1617-9625
CID: 5537422