Searched for: Department/Unit:Neuroscience Institute
Dynamic Changes in Risky Decision-Making Predict Imminent Heroin Use in Opioid Users Studied Longitudinally Through the First Months of Treatment [Meeting Abstract]
Konova, Anna; Lopez-Guzman, Silvia; Urmanche, Adelya; Ross, Stephen; Louie, Kenway; Rotrosen, John; Glimcher, Paul
ISI:000432466300077
ISSN: 0006-3223
CID: 3147812
Utilization of Immunotherapy in Head and Neck Cancers Pre-Food and Drug Administration Approval of Immune Checkpoint Inhibitors [Meeting Abstract]
Wu, S. P. P.; Tam, M.; Gerber, N. K.; Li, Z.; Schmidt, B.; Persky, M.; Sanfilippo, N. J.; Tran, T.; Jacobson, A.; DeLacure, M.; Hu, K. S.; Persky, M.; Schreiber, D. P.; Givi, B.
ISI:000428145600179
ISSN: 0360-3016
CID: 3035562
Molecular Dynamics and Docking Studies on Acetylcholinesterase (AChE) Inhibitors [Meeting Abstract]
Ali, Rejwan; Sadoqi, Mostafa; Moller, Simon; Boutajangout, Allal; Mezei, Mihaly
ISI:000430450000198
ISSN: 0006-3495
CID: 3127742
Perceptual and Executive Behavioral Deficits in ADHD and Their Differential Correlation With Microsaccade Rate [Meeting Abstract]
Mihali, Andra; Young, Allison G.; Adler, Lenard A.; Halassa, Michael; Ma, Wei Ji
ISI:000432466300500
ISSN: 0006-3223
CID: 3147712
Is Increased Response Time Variability Related to Deficient Emotional Self-Regulation in Children With ADHD? [Meeting Abstract]
Elmaghrabi, Shereen; Nahmias, Maria; Adamo, Nicoletta; Di Martino, Adriana; Somandepalli, Krishna; Patel, Varun; McLaughlin, Andrea; De Sanctis, Virginia; Castellanos, Francisco
ISI:000432466300381
ISSN: 0006-3223
CID: 3147732
Population-Based Mathematical Modeling to Deduce Disease-Causing Cardiac Na+ Channel Gating Defects [Meeting Abstract]
Campana, Chiara; Gando, Ivan; Tan, Reina Bianca; Cecchin, Frank; Coetzee, William A.; Sobie, Eric A.
ISI:000430563300167
ISSN: 0006-3495
CID: 3084792
Fluctuations in Craving and Mood State Bias Subjective Valuation in Addiction [Meeting Abstract]
Messinger, John; Lopez-Guzman, Silvia; Banavar, Nidhi; Rotrosen, John; Glimcher, Paul; Konova, Anna
ISI:000432466300579
ISSN: 0006-3223
CID: 3147702
Independent Control of Volitional and Reflexive Movements in Larval Zebrafish Locomotion [Meeting Abstract]
Ehrlich, D. E.; Schoppik, D.
ISI:000429309600223
ISSN: 1540-7063
CID: 3049352
Receptor Protein Tyrosine Phosphatases in Schizophrenia [Meeting Abstract]
Malaspina, Dolores; Kranz, Thorsten; Gonen, Oded; Harrock, Sheila; Chao, Moses
ISI:000432466300173
ISSN: 0006-3223
CID: 3147802
Thermal Transients Excite Neurons through Universal Intramembrane Mechanoelectrical Effects
Plaksin, Michael; Shapira, Einat; Kimmel, Eitan; Shoham, Shy
Modern advances in neurotechnology rely on effectively harnessing physical tools and insights towards remote neural control, thereby creating major new scientific and therapeutic opportunities. Specifically, rapid temperature pulses were shown to increase membrane capacitance, causing capacitive currents that explain neural excitation, but the underlying biophysics is not well understood. Here, we show that an intramembrane thermal-mechanical effect wherein the phospholipid bilayer undergoes axial narrowing and lateral expansion accurately predicts a potentially universal thermal capacitance increase rate of similar to 0.3%/degrees C. This capacitance increase and concurrent changes in the surface charge related fields lead to predictable exciting ionic displacement currents. The new MechanoElectrical Thermal Activation theory's predictions provide an excellent agreement with multiple experimental results and indirect estimates of latent biophysical quantities. Our results further highlight the role of electro-mechanics in neural excitation; they may also help illuminate subthreshold and novel physical cellular effects, and could potentially lead to advanced new methods for neural control. ISI:000427642300001
ISSN: 2160-3308
CID: 3015932