Searched for: Department/Unit:Otolaryngology
Modified Brief Fatigue Inventory in Head and Neck Cancer
Aynehchi, Behrad B; Obourn, Chelsea; Sundaram, Krishnamurthi; Bentsianov, Boris L; Rosenfeld, Richard M
Objective: The aim of this study is to validate the Modified Brief Fatigue Inventory (MBFI). This is the first instrument designed to measure intensity and frequency of fatigue specifically in head and neck cancer patients, potentially allowing objective measurement in addressing this common symptom in a concise yet thorough fashion. Method: The 9-item MBFI was administered to 52 consecutive cancer patients and 57 consecutive controls from the outpatient otolaryngology clinic of an academic tertiary medical center. Subject demographics, co-morbidities, cancer site, and cancer stage were recorded. Psychometric properties and predictors of the MBFI were analyzed. Results: MBFI 1-week test-retest reliability was excellent (r = 0.800, P < .001). Internal consistency was also excellent (Cronbach's alpha = .938). Construct validity of the MBFI compared to the previously validated Multidimensional Fatigue Symptom Inventory Short Form was excellent (r = 0.814, P < .001). Discriminant validity of cancer versus controls was significant (P = .027). Predictors of increased MBFI score included 1) American Society of Anesthesiologists (comorbidity) score (bivariate analysis r = 0.287, P = .039), 2) cancer stage (analysis of variance P = .007), and 3) adjuvant radiotherapy (t test P = .016). No significant relationship was found with age, gender, marital status, education, ethnicity, feeding tube, tracheostomy, or laryngectomy. Conclusion: The MBFI is a reliable and valid tool for measuring fatigue levels in head and neck cancer patients. In the context of initial assessment or posttreatment trending, this brief survey can be rapidly administered, providing valuable objective data on a very common and potentially debilitating symptom.
ORIGINAL:0011650
ISSN: 0194-5998
CID: 2368372
Newmouse models of melanoma metastasis and differences in brain tropism and metastatic growth pattern [Meeting Abstract]
Morsi, Amr M; Gazial-Sovran, Avital; Baig, Hana; Kerbel, Robert S; Golfinos, John; Wadghiri, Youssef Zaim; Hernando, Eva
ISI:000318009800369
ISSN: 0732-183x
CID: 2340752
Re: "Systematic review of complications of tonsillotomy versus tonsillectomy" [Letter]
Walton, Joanna; Ebner, Yaniv; Stewart, Michael G; April, Max M
PMID: 23197799
ISSN: 1097-6817
CID: 2348312
Non-invasive lab-on-a-chip characterization of potentially malignant oral disorders [Meeting Abstract]
Kerr, AR; Thornhill, MH; D'Apice, K; Murdoch, C; Speight, P; Hegarty, A; Redding, SW; Vigneswaran, N; Christodoulides, N; Floriano, PN; McDevitt, JT
ISI:000308718600017
ISSN: 1354-523x
CID: 2344592
Systematic review of randomized controlled trials comparing intracapsular tonsillectomy with total tonsillectomy in a pediatric population
Walton, Joanna; Ebner, Yaniv; Stewart, Michael G; April, Max M
OBJECTIVE: To perform a systematic literature review and data synthesis of level-1 evidence comparing recovery-related outcomes after intracapsular tonsillectomy (IT) (any technique) with those of total tonsillectomy (TT) (any technique) in a pediatric population. DATA SOURCES: Two independent reviewers searched the following databases: Ovid MEDLINE, including old MEDLINE and pre-MEDLINE, EBM reviews, Books@Ovid and Journals@Ovid, the Web of Science with Conference Proceedings, and references from indexed articles. STUDY SELECTION: Inclusion criteria were randomized controlled trials conducted on a pediatric population comparing IT performed by any technique of dissection with TT, also performed by any technique of dissection. Two independent reviewers determined included trials with difference of opinion resolved by a third reviewer. DATA EXTRACTION: Independent data extraction by 2 reviewers on the following outcomes: postoperative pain, analgesic use, recovery time, diet, bleeding rate, infection, and regrowth rate requiring further surgical intervention. DATA SYNTHESIS: Heterogeneity of outcome measures and lack of reporting of raw data precluded formal meta-analysis. For quantitative data that could be extracted, pooled data analysis was performed using nonparametric tests. CONCLUSION: Recovery-related outcomes for IT were superior to TT (secondary hemorrhage rate, number of days until pain free) in a pediatric population with obstructive symptoms (level-1 evidence).
PMID: 22431869
ISSN: 1538-361X
CID: 2348302
Treatment of laryngeal hyperfunction with flow phonation: A pilot study
McCullough, Gary H; Zraick, Richard I; Balou, Stamatela; Pickett, Hylan C; Rangarathnam, Balaji; Tulunay-Ugur, Ozlem E
Context: While clinical successes and descriptions have been reported in a few texts, no data exist to define the utility of flow phonation to improve voice quality in patients with laryngeal hyperfunction. Aims: To provide pilot data regarding the utility of three exercises (gargling, cup bubble blowing, and stretch-and-flow) to improve phonatory airflow during voicing in patients with laryngeal hyperfunction. Settings and Design: Outpatient Voice and Swallowing Center in a University Medical Center. Materials and Methods: Participants received five treatment sessions and were evaluated prior to treatment and after each session using a Phonatory Aerodynamic System to measure airflow during voicing tasks. Noise-to-harmonic ratio and perceptual voice measures were also obtained, as was self-perception of voice handicap. Statistical Analysis Used: Repeated All increased airflow and decreased laryngeal airway resistance over five sessions. Measures Analysis of Variance. Results: Six participants completed the protocol. All participants decreased self-perception of voice handicap and improved on noise-to-harmonic ratio and perceptual ratings of vocal quality. Conclusions: Data derived on a small sample of patients in an exploratory investigation suggest further research into the use of these three exercises to improve airflow with voicing and improve vocal quality in patients with laryngeal hyperfunction is warranted
ORIGINAL:0011643
ISSN: 2230-9748
CID: 2324852
Effects of age and exercise on neuromuscular junction plasticity in muscles of swallowing and voice
Johnson, Aaron Matthew
[Madison, Wis.] : [University of Wisconsin--Madison], 2012
Extent: xii, 164 p.
ISBN: n/a
CID: 2291952
Laser versus stapler: outcomes in endoscopic repair of Zenker diverticulum
Adam, Stewart I; Paskhover, Boris; Sasaki, Clarence T
OBJECTIVES/HYPOTHESIS: To analyze a single surgeon's experience with endoscopic CO(2) laser and stapler repair of Zenker diverticulum (ZD) by comparing dysphagia and regurgitation outcomes. STUDY DESIGN: Retrospective chart review of 148 patient charts. METHODS: Medical records of all patients receiving endoscopic repair of ZD with either CO(2) laser (61 patients) or stapler (67 patients) were reviewed. Additional data included demographics (age and sex), size (cm), preoperative and postoperative symptoms, need for revision, and complications. Symptoms of dysphagia were graded based on a modified Functional Oral Intake Scale 1 to 4 scale (1 = normal intake; 4 = severely limited/G-tube dependent). Regurgitation was also graded on a 1 to 4 scale (1 = no regurgitation; 4 = aspiration events). RESULTS: We noted no difference in patient age or defect size (laser, 3.26 cm; stapler, 3.53 cm; P .135). Significant differences were noted in return trips to the operating room for failed procedures (laser, 0; stapler, 7; P = .009), length of stay (laser, 3.19 days; stapler, 1.29 days; P < .001), time to oral intake (laser, 3.01 days; stapler, 1.22 days; P < .001). Significant improvement occurred in laser and staple patient symptom scales following surgery (P < .001). Laser dysphagia and regurgitation scores showed greater improvement when compared to stapler scores (P < .001). CONCLUSIONS: Endoscopic CO(2) laser and staple methods are effective in treating ZD. The laser can have greater efficacy and result in lower recurrence rates. Both methods are analyzed and compared.
PMID: 22870849
ISSN: 1531-4995
CID: 2207502
Criterion-based (proficiency) training to improve surgical performance
Fried, Marvin P; Kaye, Rachel J; Gibber, Marc J; Jackman, Alexis H; Paskhover, Boris P; Sadoughi, Babak; Schiff, Bradley; Fraioli, Rebecca E; Jacobs, Joseph B
OBJECTIVE To investigate whether training otorhinolaryngology residents to criterion performance levels (proficiency) on the Endoscopic Sinus Surgery Simulator produces individuals whose performance in the operating room is at least equal to those who are trained by performing a fixed number of surgical procedures. DESIGN Prospective cohort. SETTING Two academic medical centers in New York City. PARTICIPANTS Otorhinolaryngology junior residents composed of 8 experimental subjects and 6 control subjects and 6 attending surgeons. INTERVENTION Experimental subjects achieved benchmark proficiency criteria on the Endoscopic Sinus Surgery Simulator; control subjects repeated the surgical procedure twice. MAIN OUTCOME MEASURES Residents completed validated objective tests to assess baseline abilities. All subjects were videotaped performing an initial standardized surgical procedure. Residents were videotaped performing a final surgery. Videotapes were assessed for metrics by an expert panel. RESULTS Attendings outperformed the residents in most parameters on the initial procedure. Experimental and attending groups outperformed controls in some parameters on the final procedure. There was no difference between resident groups in initial performance, but the experimental subjects outperformed the control subjects in navigation in the final procedure. Most important, there was no difference in final performance between subgroups of the experimental group on the basis of the number of trials needed to attain proficiency. CONCLUSIONS Simulator training can improve resident technical skills so that each individual attains a proficiency level, despite the existence of an intrinsic range of abilities. This proficiency level translates to at least equal, if not superior, operative performance compared with that of current conventional training with finite repetition of live surgical procedures.
PMID: 23069788
ISSN: 1538-361x
CID: 2207512
IMPACT OF THE REVISED WHO SEMEN ANALYSIS REFERENCE LIMITS ON SELECTION CRITERIA FOR MICROSURGICAL VARICOCELECTOMY [Meeting Abstract]
Mehta, Akanksha; Najari, Bobby B; Rosoff, James S; Goldstein, Marc
ISI:000302912504012
ISSN: 0022-5347
CID: 2189902