Searched for: Department/Unit:Neurology
Editors' note: Pearls & Oy-sters: Challenging diagnosis of Gerstmann-Sträussler-Scheinker disease: Clinical and imaging findings [Comment]
Ganesh, Aravind; Galetta, Steven
PMID: 31988213
ISSN: 1526-632x
CID: 5092762
Editors' note: Miller Fisher syndrome and polyneuritis cranialis in COVID-19 [Comment]
Lewis, Ariane; Galetta, Steven
PMID: 32839298
ISSN: 1526-632x
CID: 5092792
Reader response: MT in anticoagulated patients: Direct oral anticoagulants versus vitamin K antagonists [Comment]
Frontera, Jennifer A
PMID: 33199530
ISSN: 1526-632x
CID: 5080152
WHEN YOU HEAR HOOFBEATS, THINK TWO ZEBRAS: THE DIAGNOSTIC VALUE OF NEUROMUSCULAR ULTRASOUND IN A PATIENT WITH CMT AND NF1 [Meeting Abstract]
Leavell, Yaowaree; Faktorovich, Svetlana; Zakin, Elina; Raynes, Hillary; Shin, Susan
ISI:000571222600023
ISSN: 0148-639x
CID: 5053442
CHARACTERISTICS AND OUTCOMES OF MYASTHENIA GRAVIS PATIENTS WITH COVID-19-A CASE SERIES [Meeting Abstract]
Kwon, P.; Granger, A.; Zakin, E.
ISI:000571222600226
ISSN: 0148-639x
CID: 5053462
RECURRENT NON-TRAUMATIC RHABDOMYOLYSIS AS PRESENTATION OF CARNITINE PALMITOYLE DEFICIENCY II IN A 65-YEAR-OLD MAN [Meeting Abstract]
Granger, Andre; Zakin, Elina
ISI:000571222600096
ISSN: 0148-639x
CID: 5053432
Measuring markers of aging and knee osteoarthritis gait using inertial measurement units
Hafer, Jocelyn F; Provenzano, Seraphina G; Kern, Kathy L; Agresta, Cristine E; Grant, John A; Zernicke, Ronald F
Differences in gait with age or knee osteoarthritis have been demonstrated in laboratory studies using optical motion capture (MoCap). While MoCap is accurate and reliable, it is impractical for assessment outside the laboratory. Inertial measurement units (IMUs) may be useful in these situations. Before IMUs are used as a surrogate for MoCap, methods that are reliable, repeatable, and that calculate metrics at similar accuracy to MoCap must be demonstrated. The purpose of this study was to compare spatiotemporal gait parameters and knee range of motion calculated via MoCap to IMU-derived variables and to compare the ability of these tools to discriminate between groups. MoCap and IMU data were collected from young, older, and adults with knee osteoarthritis during overground walking at three self-selected speeds. Walking velocity, stride length, cadence, percent of gait cycle in stance, and sagittal knee range of motion were calculated and compared between tools (MoCap and IMU), between participant groups, and across speed. There were no significant differences between MoCap and IMU outcomes, and root mean square error between tools was ≤0.05 m/s for walking velocity, ≤0.07 m for stride length, ≤0.5 strides/min for cadence, ≤5% for percent of gait cycle in stance, and ≤1.5° for knee range of motion. No interactions were present, suggesting that MoCap and IMU calculated metrics similarly across groups and speeds. These results demonstrate IMUs can accurately calculate spatiotemporal variables and knee range of motion during gait in young and older, asymptomatic and knee osteoarthritis cohorts.
PMID: 31916999
ISSN: 1873-2380
CID: 5035762
The Prevalence and Clinical Implications of Comorbid Back Pain in Shoulder Instability: A Multicenter Orthopaedic Outcomes Network (MOON) Shoulder Instability Cohort Study
Cronin, Kevin J; Wolf, Brian R; Magnuson, Justin A; Jacobs, Cale A; Ortiz, Shannon; Bishop, Julie Y; Bollier, Matthew J; Baumgarten, Keith M; Bravman, Jonathan T; Brophy, Robert H; Cox, Charles L; Feeley, Brian T; Grant, John A; Jones, Grant L; Kuhn, John E; Benjamin Ma, C; Marx, Robert G; McCarty, Eric C; Miller, Bruce S; Seidl, Adam J; Smith, Matthew V; Wright, Rick W; Zhang, Alan L; Hettrich, Carolyn M
Background/UNASSIGNED:Understanding predictors of pain is critical, as recent literature shows that comorbid back pain is an independent risk factor for worse functional and patient-reported outcomes (PROs) as well as increased opioid dependence after total joint arthroplasty. Purpose/Hypothesis/UNASSIGNED:The purpose of this study was to evaluate whether comorbid back pain would be predictive of pain or self-reported instability symptoms at the time of stabilization surgery. We hypothesized that comorbid back pain will correlate with increased pain at the time of surgery as well as with worse scores on shoulder-related PRO measures. Study Design/UNASSIGNED:Cross-sectional study; Level of evidence, 3. Methods/UNASSIGNED:As part of the Multicenter Orthopaedic Outcomes Network (MOON) Shoulder Instability cohort, patients consented to participate in pre- and intraoperative data collection. Demographic characteristics, injury history, preoperative PRO scores, and radiologic and intraoperative findings were recorded for patients undergoing surgical shoulder stabilization. Patients were also asked, whether they had any back pain. Results/UNASSIGNED:< .01). Conclusion/UNASSIGNED:Despite having similar physical findings, patients with comorbid back pain had more severe preoperative pain and self-reported symptoms of instability as well as more frequent depression and lower mental health scores. The combination of disproportionate shoulder pain, comorbid back pain and mental health conditions, and inferior preoperative expectations may affect not only the patient's preoperative state but also postoperative pain control and/or postoperative outcomes.
PMCID:7000858
PMID: 32110679
ISSN: 2325-9671
CID: 5035782
Minimally Invasive Resection of Symptomatic Cervical Rib for Treatment of Thoracic Outlet Syndrome [Case Report]
Hawks, Charlotte; Herrera-Nicol, Sarah; Pruzansky, Mark E; Jenkins, Arthur L
BACKGROUND:Neurogenic thoracic outlet syndrome treatments have high morbidity and recurrence rates. We present for the first time to our knowledge a minimally invasive spine surgery technique for complete resection of a cervical rib via a costotransversectomy approach. CASE DESCRIPTION:A patient with an 8-year history of progressive thoracic outlet syndrome presented with right C8 pain, weakness, and atrophy of her right forearm and thenar eminence. After neurogenic thoracic outlet syndrome was confirmed via electromyography and imaging revealed bilateral cervical ribs (right more than left), the patient underwent a minimally invasive spine surgery resection of the rib via a costotransversectomy and was discharged home the same day. The patient's pain and weakness gradually improved over a 2-year follow-up period. CONCLUSIONS:Resection of a cervical rib via minimally invasive spine surgery costotransversectomy is safe and well tolerated compared with existing surgical treatments such as transaxillary, supraclavicular, and infraclavicular approaches.
PMID: 32194276
ISSN: 1878-8769
CID: 5036172
Does the Symmetry of Patellar Morphology Matter When Matching Osteochondral Allografts for Osteochondral Defects Involving the Central Ridge of the Patella?
Patel, Karan; Salka, Nabeel S; Ramme, Austin; Scott, Jaron C; Grant, John A
OBJECTIVE:The purpose of this study was to determine if differences in Wiberg classification play a role in the ability of donor patellar osteochondral allografts to match the native patellar surface when treating osteochondral defects of the patellar apex. DESIGN/METHODS:Twenty (10 Wiberg I and 10 Wiberg II/III) human patellae were designated as the recipient. Each recipient was size-matched to both a Wiberg I and a Wiberg II/III patellar donor. A 16-mm circular osteochondral "defect" was created on the central ridge of the recipient patella. The randomly ordered donor Wiberg I or Wiberg II/III plug was harvested from a homologous location and transplanted into the recipient. The recipient was then nano-CT (computed tomography) scanned, digitally reconstructed, registered to the initial nano-CT scan of the recipient patella, and processed to determine root mean squared circumferential step-off heights as well as surface height deviation. The process was then repeated for the other allograft plug. RESULTS:= 0.68). CONCLUSIONS:For osteochondral allograft sizes up to 16 mm there appears to be no advantage to match donor and recipient patellar morphology. Further study is warranted to evaluate defects requiring larger graft sizes.
PMID: 32819146
ISSN: 1947-6043
CID: 5035802