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Department/Unit:Cell Biology

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14241


Inhibition of TGF beta as a strategy to convert the irradiated tumor into in situ individualized vaccine [Meeting Abstract]

Vanpouille-Box, Claire I; Diamond, Julie M; Zavadil, Jiri; Babb, James; Schaue, Doerthe; Barcellos-Hoff, Mary Helen; McBride, William H; Formenti, Silvia C; Demaria, Sandra
ISI:000349906905095
ISSN: 1538-7445
CID: 1598452

Concomitant radiotherapy (RT) and TGF beta neutralizing antibodies alters tumor microenvironment and promotes tumor regression [Meeting Abstract]

Pellicciotta, Ilenia; Du, Shisuo; Formenti, Silvia; Barcellos-Hoff, Mary Helen
ISI:000349910205208
ISSN: 1538-7445
CID: 1599322

An open science resource for establishing reliability and reproducibility in functional connectomics

Zuo, Xi-Nian; Anderson, Jeffrey S; Bellec, Pierre; Birn, Rasmus M; Biswal, Bharat B; Blautzik, Janusch; Breitner, John C S; Buckner, Randy L; Calhoun, Vince D; Castellanos, F Xavier; Chen, Antao; Chen, Bing; Chen, Jiangtao; Chen, Xu; Colcombe, Stanley J; Courtney, William; Craddock, R Cameron; Di Martino, Adriana; Dong, Hao-Ming; Fu, Xiaolan; Gong, Qiyong; Gorgolewski, Krzysztof J; Han, Ying; He, Ye; He, Yong; Ho, Erica; Holmes, Avram; Hou, Xiao-Hui; Huckins, Jeremy; Jiang, Tianzi; Jiang, Yi; Kelley, William; Kelly, Clare; King, Margaret; LaConte, Stephen M; Lainhart, Janet E; Lei, Xu; Li, Hui-Jie; Li, Kaiming; Li, Kuncheng; Lin, Qixiang; Liu, Dongqiang; Liu, Jia; Liu, Xun; Liu, Yijun; Lu, Guangming; Lu, Jie; Luna, Beatriz; Luo, Jing; Lurie, Daniel; Mao, Ying; Margulies, Daniel S; Mayer, Andrew R; Meindl, Thomas; Meyerand, Mary E; Nan, Weizhi; Nielsen, Jared A; O'Connor, David; Paulsen, David; Prabhakaran, Vivek; Qi, Zhigang; Qiu, Jiang; Shao, Chunhong; Shehzad, Zarrar; Tang, Weijun; Villringer, Arno; Wang, Huiling; Wang, Kai; Wei, Dongtao; Wei, Gao-Xia; Weng, Xu-Chu; Wu, Xuehai; Xu, Ting; Yang, Ning; Yang, Zhi; Zang, Yu-Feng; Zhang, Lei; Zhang, Qinglin; Zhang, Zhe; Zhang, Zhiqiang; Zhao, Ke; Zhen, Zonglei; Zhou, Yuan; Zhu, Xing-Ting; Milham, Michael P
Efforts to identify meaningful functional imaging-based biomarkers are limited by the ability to reliably characterize inter-individual differences in human brain function. Although a growing number of connectomics-based measures are reported to have moderate to high test-retest reliability, the variability in data acquisition, experimental designs, and analytic methods precludes the ability to generalize results. The Consortium for Reliability and Reproducibility (CoRR) is working to address this challenge and establish test-retest reliability as a minimum standard for methods development in functional connectomics. Specifically, CoRR has aggregated 1,629 typical individuals' resting state fMRI (rfMRI) data (5,093 rfMRI scans) from 18 international sites, and is openly sharing them via the International Data-sharing Neuroimaging Initiative (INDI). To allow researchers to generate various estimates of reliability and reproducibility, a variety of data acquisition procedures and experimental designs are included. Similarly, to enable users to assess the impact of commonly encountered artifacts (for example, motion) on characterizations of inter-individual variation, datasets of varying quality are included.
PMCID:4421932
PMID: 25977800
ISSN: 2052-4463
CID: 1579592

Abstract 33: Stress Offloading through Mechanomodulation is Associated with Down-Regulation of Inflammatory Pathways in a Large Animal Model

Januszyk, Michael; Wong, Victor W; Bhatt, Kirit; Vial, Ivan N; Dauskardt, Reinhold; Longaker, Michael T; Gurtner, Geoffrey C
PMID: 25942144
ISSN: 1529-4242
CID: 1569232

Abstract 10: Global and Endothelial Cell Specific Deletion of SDF-1 Results in Delayed Wound Healing

Maan, Zeshaan N; Ho, Natalie High School; Rennert, Robert C; Duscher, Dominik; Sorkin, Michael; Rodrigues, Melanie; Chen, Jerry; Vial, Ivan N; Januszyk, Michael; Findlay, Michael; Hu, Michael; Walmsley, Graham; Longaker, Michael T; Gurtner, Geoffrey C
PMID: 25942121
ISSN: 1529-4242
CID: 1569202

Abstract 15: Characterization of the Endothelial Progenitor Cell from Adult Tissue using Vav/Cre RFP-GFP Murine Model and Single Cell Microfluidics

Rodrigues, Melanie; Rennert, Robert C; Bishop, Sarah; Januszyk, Michael; Maan, Zeshaan; Sorkin, Michael; Duscher, Dominik; Gurtner, Geoffrey C
PMID: 25942126
ISSN: 1529-4242
CID: 1569212

Abstract 8: SDF-1 Regulates Adipose Niche Homeostasis and Adipose Derived Stromal Cell Function

Maan, Zeshaan N; Rennert, Robert C; Duscher, Dominik; Januszyk, Michael; Paik, Kevin; Chung, Michael T; Paik, Kevin; Fujiwara, Toshihiro; Rodrigues, Melanie; Ho, Natalie High School; Baker, Hutton High School; Perez, Marcelina; Hu, Michael; Sorkin, Michael; Longaker, Michael T; Gurtner, Geoffrey C
PMID: 25942119
ISSN: 1529-4242
CID: 1569192

Abstract 54: TGF Beta and BMP Signaling Pathways Influence Regenerative Capacity of Calvarial Bones via Cross-Talk and Modulation of Apoptosis: The Potential Therapeutic Role of Small Molecule Inhibitors of TGF Beta Signaling

Senarath-Yapa, Kshemendra; Meyer, Nathaniel; Li, Shuli; Longaker, Michael T; Quarto, Natalina
PMID: 25942165
ISSN: 1529-4242
CID: 1569252

Abstract 151: short hairpin RNA interference therapy for diabetic murine wound closure and hindlimb ischemia

Paik, Kevin J; Rennert, Robert; Chung, Michael T; Sorkin, Michael; Duscher, Dominik; Atashroo, David; Chen, Hsin-Han; Morrison, Shane D; Zimmermann, Andrew; Nauta, Allison; Ko, Sae-Hee; Tevlin, Ruth; Zielins, Elizabeth; Hu, Michael S; McArdle, Adrian; Walmsley, Graham; Senarath-Yapa, Kshemendra; Hong, Wan Xing; Garza, Rebecca M; Duldulao, Christopher; Wearda, Taylor; Momeni, Arash; Wu, Joseph C; Gurtner, Geoffrey C; Longaker, Michael T; Wan, Derrick C
PMID: 25942261
ISSN: 1529-4242
CID: 1569322

The separation of sexual activity and reproduction in human social evolution

Morin, Scott; Keefe, David; Naftolin, Frederick
In industrialized societies the progression of natural selection has been determined and in many cases superseded by social evolution. In the case of reproduction, there has been a decline and delay of childbearing without diminished sexual activity. While this has value for these societies, there are penalties associated with barren cycles. These include increases in endometriosis and breast and genital cancer. There also are associated issues regarding population movements that fill the "vacuums" left by underpopulation. These matters are of more than passing interest as we cope with unintended consequences of Man's dominance over the environment and other life forms.
PMID: 25015809
ISSN: 0065-2598
CID: 1565312